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The map label for this gene is metH

Identifier: 221230154

GI number: 221230154

Start: 1556874

End: 1560494

Strand: Direct

Name: metH

Synonym: MLBr_01307

Alternate gene names: 221230154

Gene position: 1556874-1560494 (Clockwise)

Preceding gene: 221230150

Following gene: 221230155

Centisome position: 47.64

GC content: 58.63

Gene sequence:

>3621_bases
ATGCGTGTAACTGCCGCTAACCAACATCAGTACGACACCGATCTCCTCGAGACTTTGGCGCAGCGTGTGATGGTGGGTGA
CGGCGCAATGGGTACTCAGCTCCAGGACGCGGAACTTACGTTAGATGATTTCCGCGGCCTGGAGGGCTGCAACGAGATTC
TCAACGAAACGCGTCCTGACGTGCTGGAAACCATCCACCGACGCTACTTCGAGGCAGGTGCGGACCTCGTCGAGACCAAC
ACTTTCGGCTGCAACCTGTCCAACCTTGGTGACTACGACATCGCCGACAAGATCAGGGACTTGTCGCAGCGGGGCACCGT
GATTGCGCGACGGGTCGCCGACGAGCTGACCACCCCCGACCACAAGCGATACGTGCTGGGGTCGATGGGACCAGGCACCA
AGTTGCCCACCCTGGGCCACACCGAGTACCGGGTCGTTCGAGACGCCTACACCGAGTCGGCGTTAGGCATGCTGGACGGT
GGCGCTGACGCCGTACTGGTTGAAACCTGTCAGGACTTGCTGCAGCTCAAGGCTGCGGTGCTGGGCTCGCGGCGCGCGAT
GACACAGGCCGGTCGGCACATTCCGGTCTTCGTCCACGTGACTGTCGAGACGACCGGAACGATGCTGCTGGGAAGTGAGA
TCGGCGCTGCACTGGCTGCCGTCGAGCCGCTCGGTGTCGACATGATCGGTTTGAACTGCGCAACGGGCCCCGCTGAGATG
AGTGAGCATCTGCGGCACTTGTCCAAGCATGCCCGCATCCCGGTGTCGGTGATGCCCAACGCCGGGCTGCCGGTGCTGGG
TGCCAAGGGAGCTGAATACCCGCTGCAGCCCGACGAATTGGCCGAAGCTTTGGCTGGGTTCATCGCTGAATTTGGTCTTT
CGTTGGTAGGTGGCTGCTGTGGTACCACCCCGGACCACATCCGGGAAGTGGCCGCAGCGGTAGCCAGATGCAACGACGGG
ACAGTGCCACGCGGTGAGCGTCATGTGACCTATGAGCCGTCGGTATCGTCGCTGTATACAGCCATTCCATTCGCCCAAAA
ACCCTCGGTTCTGATGATCGGTGAGCGTACGAATGCCAACGGCTCCAAGGTTTTTCGTGAGGCAATGATCGCCGAGGACT
ATCAAAAGTGTCTAGATATCGCCAAGGACCAAACCCGTGGCGGCGCACACCTGCTGGATCTGTGTGTCGATTACGTCGGC
CGCAACGGTGTGGCCGACATGAAGGCGTTGGCCGGTCGGCTTGCAACGGTGTCGACATTGCCGATCATGCTGGACTCTAC
CGAAATACCGGTGCTGCAGGCAGGTTTGGAGCACCTGGGCGGGCGCTGCGTGATCAATTCCGTCAACTACGAGGACGGTG
ACGGTCCCGAGTCACGGTTTGTCAAGACCATGGAGCTGGTCGCCGAGCACGGAGCGGCGGTGGTTGCGCTGACCATCGAC
GAACAGGGTCAGGCCCGCACCGTTGAGAAGAAGGTCGAAGTCGCGGAGCGGCTTATCAATGACATTACGAGTAACTGGGG
CGTTGATAAATCGGCGATTCTCATCGATTGCTTGACTTTTACTATTGCCACTGGCCAGGAGGAGTCACGCAAAGACGGCA
TTGAGACCATCGACGCGATTCGTGAGCTGAAGAAGCGGCACCCAGCGGTGCAGACTACGCTGGGGTTGTCCAACATCTCC
TTCGGTCTCAATCCTTCTGCACGCCAAGTTCTTAACTCTGTTTTTCTACATGAATGTCAGGAAGCAGGACTGGATTCGGC
GATTGTGCACGCTTCAAAGATATTGCCCATCAACCGGATACCCGAAGAACAGCGCCAGGCTGCGCTGGATCTAGTGTATG
ACCGCCGTCGCGAAGGCTACGACCCATTGCAGAAGCTGATGTGGTTATTCAAAGGTGTGTCGTCGCCATCGTCGAAGGAA
ACACGGGAGGCAGAACTCGCTAAGCTGCCGTTGTTCGACCGGTTAGCACAGCGGATCGTCGACGGCGAGCGCAACGGGTT
AGATGTTGATCTCGACGAGGCAATGACCCAGAAACCGCCGTTGGCGATCATCAACGAGAACCTGCTGGACGGCATGAAGA
CAGTCGGTGAATTGTTCGGCTCTGGGCAGATGCAGCTGCCTTTCGTGTTGCAGTCGGCCGAGGTTATGAAAGCAGCGGTG
GCTTATCTAGAACCGCACATGGAGAAATCCGACTGTGACTTCGGTAAGGGGTTAGCCAAAGGACGGATTGTGCTGGCTAC
CGTCAAAGGAGATGTGCACGATATTGGCAAAAACCTCGTCGATATCATTCTGAGCAACAACGGCTACGAAGTGGTAAACC
TCGGCATCAAGCAGCCGATTACCAACATTCTCGAGGTGGCCGAGGACAAAAGCGCCGACGTAGTCGGGATGTCGGGCTTG
CTGGTGAAATCGACTGTGATCATGAAGGAAAACCTCGAGGAGATGAACACTCGCGGAGTCGCTGAGAAATTCCCAGTGCT
GCTCGGCGGCGCGGCGTTGACCCGCAGCTATGTGGAAAACGACCTGGCCGAAGTCTATGAGGGCGAAGTGCATTACGCAC
GAGACGCTTTCGAGGGTTTGAAGTTGATGGACACCATTATGAGCGCCAAGCGCGGCGAGGCGCTTGCGCCGGGGAGCCCG
GAGTCCTTAGCTGCAGAAGCAGACCGCAATAAGGAAACTGAGCGCAAGGCACGTCATGAGCGGTCCAAACGCATTGCAGT
GCAGCGTAAGGCTGCCGAAGAGCCAGTTGAGGTTCCCGAACGCTCCGATGTTCCGAGTGATGTCGAGGTTCCGGCGCCGC
CGTTCTGGGGTTCGCGGATCATCAAGGGTCTGGCGGTGGCCGACTATACCGGGTTCCTCGACGAGCGCGCGTTGTTCTTG
GGTCAGTGGGGATTACGTGGTGTGCGCGGCGGTGCGGGGCCCTCGTACGAGGATTTGGTGCAGACCGAGGGCCGGCCGCG
GTTGCGCTACTGGCTAGACCGATTGTCCACCTACGGCGTCTTGGCGTACGCCGCCGTGGTGTACGGTTACTTCCCGGCGG
TGTCCGAAGACAACGATATTGTCGTGCTCGCTGAGCCGAGACCGGACGCCGAGCAGCGGTACCGGTTCACCTTCCCGCGT
CAGCAACGCGGTCGGTTCCTGTGCATTGCCGATTTTATTCGATCCCGGGATCTGGCGACCGAGCGGAGTGAGGTGGATGT
TTTGCCGTTCCAGCTGGTGACCATGGGTCAACCCATTGCTGACTTCGTTGGCGAGTTGTTCGTGTCCAATTCCTATCGTG
ATTATCTTGAAGTGCATGGCATCGGTGTGCAGCTAACCGAGGCGCTGGCCGAATACTGGCACCGGCGCATTCGTGAAGAG
CTGAAATTCTCCGGAAACCGGACGATGTCGGCTGACGATCCCGAGGCCGTCGAGGACTATTTCAAGCTCGGCTACCGAGG
TGCCCGCTTCGCGTTCGGGTATGGAGCATGCCCGGACCTGGAGGACCGGATCAAGATGATGGAGCTGCTTCAACCCGAAC
GCATCGGTGTAACGATATCTGAAGAGTTGCAGTTACATCCCGAGCAATCGACTGATGCGTTCGTGCTGCACCATCCGGCG
GCTAAGTACTTCAACGTCTGA

Upstream 100 bases:

>100_bases
TAACGGCTCGATGAGGGGGCACTTCACCGTACGTACGAGGTACTGCGGGGCAGTATTAGGTAACTAAGCGATTTGTATAG
GTCCACTATCCTTATGCCTT

Downstream 100 bases:

>100_bases
GGGCTACCTCGACTCGTCAGCCTTTCAGGTGTGCTGCAGCATTGGCTCCTGGGAAGTTTCACCTATATGGAATTTTCCCA
ACAGAAAGACTCCTTTAGCT

Product: 5-methyltetrahydrofolate-homocysteine methyltransferase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS

Number of amino acids: Translated: 1206; Mature: 1206

Protein sequence:

>1206_residues
MRVTAANQHQYDTDLLETLAQRVMVGDGAMGTQLQDAELTLDDFRGLEGCNEILNETRPDVLETIHRRYFEAGADLVETN
TFGCNLSNLGDYDIADKIRDLSQRGTVIARRVADELTTPDHKRYVLGSMGPGTKLPTLGHTEYRVVRDAYTESALGMLDG
GADAVLVETCQDLLQLKAAVLGSRRAMTQAGRHIPVFVHVTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEM
SEHLRHLSKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVGGCCGTTPDHIREVAAAVARCNDG
TVPRGERHVTYEPSVSSLYTAIPFAQKPSVLMIGERTNANGSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVDYVG
RNGVADMKALAGRLATVSTLPIMLDSTEIPVLQAGLEHLGGRCVINSVNYEDGDGPESRFVKTMELVAEHGAAVVALTID
EQGQARTVEKKVEVAERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAIRELKKRHPAVQTTLGLSNIS
FGLNPSARQVLNSVFLHECQEAGLDSAIVHASKILPINRIPEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSSKE
TREAELAKLPLFDRLAQRIVDGERNGLDVDLDEAMTQKPPLAIINENLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAV
AYLEPHMEKSDCDFGKGLAKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPITNILEVAEDKSADVVGMSGL
LVKSTVIMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSP
ESLAAEADRNKETERKARHERSKRIAVQRKAAEEPVEVPERSDVPSDVEVPAPPFWGSRIIKGLAVADYTGFLDERALFL
GQWGLRGVRGGAGPSYEDLVQTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSEDNDIVVLAEPRPDAEQRYRFTFPR
QQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQPIADFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREE
LKFSGNRTMSADDPEAVEDYFKLGYRGARFAFGYGACPDLEDRIKMMELLQPERIGVTISEELQLHPEQSTDAFVLHHPA
AKYFNV

Sequences:

>Translated_1206_residues
MRVTAANQHQYDTDLLETLAQRVMVGDGAMGTQLQDAELTLDDFRGLEGCNEILNETRPDVLETIHRRYFEAGADLVETN
TFGCNLSNLGDYDIADKIRDLSQRGTVIARRVADELTTPDHKRYVLGSMGPGTKLPTLGHTEYRVVRDAYTESALGMLDG
GADAVLVETCQDLLQLKAAVLGSRRAMTQAGRHIPVFVHVTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEM
SEHLRHLSKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVGGCCGTTPDHIREVAAAVARCNDG
TVPRGERHVTYEPSVSSLYTAIPFAQKPSVLMIGERTNANGSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVDYVG
RNGVADMKALAGRLATVSTLPIMLDSTEIPVLQAGLEHLGGRCVINSVNYEDGDGPESRFVKTMELVAEHGAAVVALTID
EQGQARTVEKKVEVAERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAIRELKKRHPAVQTTLGLSNIS
FGLNPSARQVLNSVFLHECQEAGLDSAIVHASKILPINRIPEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSSKE
TREAELAKLPLFDRLAQRIVDGERNGLDVDLDEAMTQKPPLAIINENLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAV
AYLEPHMEKSDCDFGKGLAKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPITNILEVAEDKSADVVGMSGL
LVKSTVIMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSP
ESLAAEADRNKETERKARHERSKRIAVQRKAAEEPVEVPERSDVPSDVEVPAPPFWGSRIIKGLAVADYTGFLDERALFL
GQWGLRGVRGGAGPSYEDLVQTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSEDNDIVVLAEPRPDAEQRYRFTFPR
QQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQPIADFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREE
LKFSGNRTMSADDPEAVEDYFKLGYRGARFAFGYGACPDLEDRIKMMELLQPERIGVTISEELQLHPEQSTDAFVLHHPA
AKYFNV
>Mature_1206_residues
MRVTAANQHQYDTDLLETLAQRVMVGDGAMGTQLQDAELTLDDFRGLEGCNEILNETRPDVLETIHRRYFEAGADLVETN
TFGCNLSNLGDYDIADKIRDLSQRGTVIARRVADELTTPDHKRYVLGSMGPGTKLPTLGHTEYRVVRDAYTESALGMLDG
GADAVLVETCQDLLQLKAAVLGSRRAMTQAGRHIPVFVHVTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEM
SEHLRHLSKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVGGCCGTTPDHIREVAAAVARCNDG
TVPRGERHVTYEPSVSSLYTAIPFAQKPSVLMIGERTNANGSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVDYVG
RNGVADMKALAGRLATVSTLPIMLDSTEIPVLQAGLEHLGGRCVINSVNYEDGDGPESRFVKTMELVAEHGAAVVALTID
EQGQARTVEKKVEVAERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAIRELKKRHPAVQTTLGLSNIS
FGLNPSARQVLNSVFLHECQEAGLDSAIVHASKILPINRIPEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSSKE
TREAELAKLPLFDRLAQRIVDGERNGLDVDLDEAMTQKPPLAIINENLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAV
AYLEPHMEKSDCDFGKGLAKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPITNILEVAEDKSADVVGMSGL
LVKSTVIMKENLEEMNTRGVAEKFPVLLGGAALTRSYVENDLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSP
ESLAAEADRNKETERKARHERSKRIAVQRKAAEEPVEVPERSDVPSDVEVPAPPFWGSRIIKGLAVADYTGFLDERALFL
GQWGLRGVRGGAGPSYEDLVQTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSEDNDIVVLAEPRPDAEQRYRFTFPR
QQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQPIADFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREE
LKFSGNRTMSADDPEAVEDYFKLGYRGARFAFGYGACPDLEDRIKMMELLQPERIGVTISEELQLHPEQSTDAFVLHHPA
AKYFNV

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain

Homologues:

Organism=Homo sapiens, GI169790923, Length=1270, Percent_Identity=31.0236220472441, Blast_Score=496, Evalue=1e-140,
Organism=Escherichia coli, GI1790450, Length=1239, Percent_Identity=30.9927360774818, Blast_Score=527, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17535405, Length=1273, Percent_Identity=31.1861743912019, Blast_Score=505, Evalue=1e-143,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): METH_MYCLE (Q49775)

Other databases:

- EMBL:   U00017
- EMBL:   AL035310
- EMBL:   AL583921
- PIR:   E87072
- PIR:   S72842
- RefSeq:   NP_301940.1
- ProteinModelPortal:   Q49775
- EnsemblBacteria:   EBMYCT00000029082
- GeneID:   910429
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1307
- NMPDR:   fig|272631.1.peg.812
- Leproma:   ML1307
- GeneTree:   EBGT00050000017538
- HOGENOM:   HBG289648
- OMA:   YVTDASR
- ProtClustDB:   CLSK872016
- BioCyc:   MLEP272631:ML1307-MONOMER
- BRENDA:   2.1.1.13
- GO:   GO:0005622
- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223
- Gene3D:   G3DSA:3.40.50.280
- Gene3D:   G3DSA:3.20.20.20
- Gene3D:   G3DSA:3.10.196.10
- Gene3D:   G3DSA:1.10.1240.10
- Gene3D:   G3DSA:3.20.20.330
- PIRSF:   PIRSF000381
- TIGRFAMs:   TIGR02082

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans; SSF52242 Cbl-bd; SSF51717 DHP_synth_like; SSF56507 Met_synth_B12; SSF47644 Met_synth_Cbl-bd; SSF82282 S_methyl_trans

EC number: =2.1.1.13

Molecular weight: Translated: 132394; Mature: 132394

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50974 ADOMET_ACTIVATION; PS51332 B12_BINDING; PS51337 B12_BINDING_NTER; PS50970 HCY; PS50972 PTERIN_BINDING; PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 798-798 BINDING 954-954 BINDING 1149-1149 BINDING 1153-1153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTAANQHQYDTDLLETLAQRVMVGDGAMGTQLQDAELTLDDFRGLEGCNEILNETRPD
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCHH
VLETIHRRYFEAGADLVETNTFGCNLSNLGDYDIADKIRDLSQRGTVIARRVADELTTPD
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HKRYVLGSMGPGTKLPTLGHTEYRVVRDAYTESALGMLDGGADAVLVETCQDLLQLKAAV
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LGSRRAMTQAGRHIPVFVHVTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEM
HHHHHHHHHCCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCCHHHH
SEHLRHLSKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVGGCC
HHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GTTPDHIREVAAAVARCNDGTVPRGERHVTYEPSVSSLYTAIPFAQKPSVLMIGERTNAN
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCC
GSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVDYVGRNGVADMKALAGRLATVSTL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
PIMLDSTEIPVLQAGLEHLGGRCVINSVNYEDGDGPESRFVKTMELVAEHGAAVVALTID
EEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEC
EQGQARTVEKKVEVAERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RELKKRHPAVQTTLGLSNISFGLNPSARQVLNSVFLHECQEAGLDSAIVHASKILPINRI
HHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSSKETREAELAKLPLFDRLAQRIV
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
DGERNGLDVDLDEAMTQKPPLAIINENLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAV
CCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
AYLEPHMEKSDCDFGKGLAKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPI
HHHHCCCCCCCCCHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCHHHHH
TNILEVAEDKSADVVGMSGLLVKSTVIMKENLEEMNTRGVAEKFPVLLGGAALTRSYVEN
HHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCHHHHHHHHHHH
DLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSPESLAAEADRNKETERKARHE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
RSKRIAVQRKAAEEPVEVPERSDVPSDVEVPAPPFWGSRIIKGLAVADYTGFLDERALFL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GQWGLRGVRGGAGPSYEDLVQTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSEDNDI
HHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VVLAEPRPDAEQRYRFTFPRQQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQPIA
EEEECCCCCHHHCEEECCCHHHCCCEEEHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHH
DFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGNRTMSADDPEAVEDY
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FKLGYRGARFAFGYGACPDLEDRIKMMELLQPERIGVTISEELQLHPEQSTDAFVLHHPA
HHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEHHHHEECCCCCCCEEEEECCC
AKYFNV
HHHCCC
>Mature Secondary Structure
MRVTAANQHQYDTDLLETLAQRVMVGDGAMGTQLQDAELTLDDFRGLEGCNEILNETRPD
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCHH
VLETIHRRYFEAGADLVETNTFGCNLSNLGDYDIADKIRDLSQRGTVIARRVADELTTPD
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HKRYVLGSMGPGTKLPTLGHTEYRVVRDAYTESALGMLDGGADAVLVETCQDLLQLKAAV
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LGSRRAMTQAGRHIPVFVHVTVETTGTMLLGSEIGAALAAVEPLGVDMIGLNCATGPAEM
HHHHHHHHHCCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCCHHHH
SEHLRHLSKHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALAGFIAEFGLSLVGGCC
HHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GTTPDHIREVAAAVARCNDGTVPRGERHVTYEPSVSSLYTAIPFAQKPSVLMIGERTNAN
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCC
GSKVFREAMIAEDYQKCLDIAKDQTRGGAHLLDLCVDYVGRNGVADMKALAGRLATVSTL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
PIMLDSTEIPVLQAGLEHLGGRCVINSVNYEDGDGPESRFVKTMELVAEHGAAVVALTID
EEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEC
EQGQARTVEKKVEVAERLINDITSNWGVDKSAILIDCLTFTIATGQEESRKDGIETIDAI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RELKKRHPAVQTTLGLSNISFGLNPSARQVLNSVFLHECQEAGLDSAIVHASKILPINRI
HHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PEEQRQAALDLVYDRRREGYDPLQKLMWLFKGVSSPSSKETREAELAKLPLFDRLAQRIV
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
DGERNGLDVDLDEAMTQKPPLAIINENLLDGMKTVGELFGSGQMQLPFVLQSAEVMKAAV
CCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
AYLEPHMEKSDCDFGKGLAKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNLGIKQPI
HHHHCCCCCCCCCHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEECCHHHHH
TNILEVAEDKSADVVGMSGLLVKSTVIMKENLEEMNTRGVAEKFPVLLGGAALTRSYVEN
HHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCHHHHHHHHHHH
DLAEVYEGEVHYARDAFEGLKLMDTIMSAKRGEALAPGSPESLAAEADRNKETERKARHE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
RSKRIAVQRKAAEEPVEVPERSDVPSDVEVPAPPFWGSRIIKGLAVADYTGFLDERALFL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GQWGLRGVRGGAGPSYEDLVQTEGRPRLRYWLDRLSTYGVLAYAAVVYGYFPAVSEDNDI
HHCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
VVLAEPRPDAEQRYRFTFPRQQRGRFLCIADFIRSRDLATERSEVDVLPFQLVTMGQPIA
EEEECCCCCHHHCEEECCCHHHCCCEEEHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHH
DFVGELFVSNSYRDYLEVHGIGVQLTEALAEYWHRRIREELKFSGNRTMSADDPEAVEDY
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FKLGYRGARFAFGYGACPDLEDRIKMMELLQPERIGVTISEELQLHPEQSTDAFVLHHPA
HHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEHHHHEECCCCCCCEEEEECCC
AKYFNV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002