Click here to switch to the map view.

The map label for this gene is murI

Identifier: 221230068

GI number: 221230068

Start: 1369245

End: 1370063

Strand: Direct

Name: murI

Synonym: MLBr_01172

Alternate gene names: 221230068

Gene position: 1369245-1370063 (Clockwise)

Preceding gene: 221230067

Following gene: 221230069

Centisome position: 41.9

GC content: 62.39

Gene sequence:

>819_bases
ATGAGCTCGCCGCTGTTGCCCGTTGGGGTCTTTGACTCCGGCGTCGGCGGCTTGACAGTCGCGCGGGCGATCATCGACCA
GCTGCCTGACGAGGATATTGTGTATGTGGGTGACACCGGCAACGGCCCGTACGGACCGCTCTCTATCCCTGAGATTCGTG
CGCACGCGTTGGCTATCTGTGACGACCTAGTAGGCCGCGGCGTAAAGATACTGGTGATTGCATGCAACACGGCGTCTGCA
GCGTGCCTGCGAGACGCTCGTGAGCGCTACGATGTGCCCGTAGTCGAGGTCATTTTGCCGGCAGTGCGCCGCGCGGTTGC
CGCCACCCGCAACGGCCGCATTGGGGTCATCGGCACCCGGGCCACCATAGCCTCGCACGCGTACCAAGATGCGTTTGCTG
CTGCCCGCGACACCGAGATCACCGCGGTGGCGTGCCCACGCTTTGTCGACTTCGTCGAGTGCGGTGTGACCAGCGGTCGT
CAGGTGCTCGGACTGGCTGAAGGGTATCTGGAGCCGCTGCAGCGTTCCGGGGTTGACACGCTGGTGTTGGGTTGCACACA
CTACCCACTGCTGGCTGGACTGATTCAACTGGCGATGGGAGAAAACGTCACGCTGGTCTCCAGCGCCGAGGAGACCGCCA
AGGAAGTGCTGCGGGTGCTTACCGAAAGAGACCTGTTGCGTCGACATGACGCGCCGCCCGTTAACCGGGTTTTCGAAGCT
ACCGGTGACCCCGAAGCGTTCATTCAGTTGGCTGCGCGATTTCTCGGTCCAGCGGTGAGTGGTGTTCAACCTGCGCGACT
TCATTCTCGTGTCCGTTAG

Upstream 100 bases:

>100_bases
GCGCGATCTCAGGTGTCGTGGCCGCATATCTGTTGTCCGCGCCGGAACGTAAGACCCGCGCGCTCAAAGAAGCCGGCACC
GATTCGCCGCGTCTGAAGAC

Downstream 100 bases:

>100_bases
ATGAGTGCAAGAGATTCTGATCACCTTAATGGGCAATGTTTTCCTCATCCTGGTATCGGGCATGGCACAGTAGTGACCGT
GCGCATAACCGTGCTCGGCT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAICDDLVGRGVKILVIACNTASA
ACLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTRATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGR
QVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEA
TGDPEAFIQLAARFLGPAVSGVQPARLHSRVR

Sequences:

>Translated_272_residues
MSSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAICDDLVGRGVKILVIACNTASA
ACLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTRATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGR
QVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEA
TGDPEAFIQLAARFLGPAVSGVQPARLHSRVR
>Mature_271_residues
SSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAICDDLVGRGVKILVIACNTASAA
CLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTRATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGRQ
VLGLAEGYLEPLQRSGVDTLVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEAT
GDPEAFIQLAARFLGPAVSGVQPARLHSRVR

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=235, Percent_Identity=34.468085106383, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_MYCLB (B8ZR57)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503484.1
- ProteinModelPortal:   B8ZR57
- SMR:   B8ZR57
- EnsemblBacteria:   EBMYCT00000085158
- GeneID:   7327047
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016063
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- ProtClustDB:   PRK00865
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 28855; Mature: 28724

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAIC
CCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
DDLVGRGVKILVIACNTASAACLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTR
HHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECH
ATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGRQVLGLAEGYLEPLQRSGVDT
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCE
LVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEA
EEECCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
TGDPEAFIQLAARFLGPAVSGVQPARLHSRVR
CCCHHHHHHHHHHHHCHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
SSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAIC
CCCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
DDLVGRGVKILVIACNTASAACLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTR
HHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECH
ATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGRQVLGLAEGYLEPLQRSGVDT
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCE
LVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEA
EEECCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
TGDPEAFIQLAARFLGPAVSGVQPARLHSRVR
CCCHHHHHHHHHHHHCHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA