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The map label for this gene is atpH

Identifier: 221230050

GI number: 221230050

Start: 1332096

End: 1333436

Strand: Direct

Name: atpH

Synonym: MLBr_01142

Alternate gene names: 221230050

Gene position: 1332096-1333436 (Clockwise)

Preceding gene: 221230049

Following gene: 221230051

Centisome position: 40.76

GC content: 60.18

Gene sequence:

>1341_bases
ATGTCAACATTCATTGGTCAGTTGGTTGGCTTCGCTGCCATCGTCTATTTGGTGTGGTGGTATGTAGTGCCGCCGGTGTG
CCGTTTGATGAGAGCTCGGCGGGACGCGGTGCGCCAGCAGTTGACTGAGGCGGCCGAGGCCGCAGATCGGCTAGTTGAAG
CGAGCCAGGCCCATACCAAGGCCACCGAAGACGCCAAGGTCGAGGCCCAGCGTGTCGTCAAAGAGGCTGTCGAAGACGCC
AAGCGCATTGTTGAGCAATTGCAAGCCCAGGCCGATGTCGAGGCGGAACGCATCAAGCTACAGGGAGCTCGCCAAGTCGA
ACTGCTACGGGCCCAGTTGACCCGTCAGCTTCGCCTGAAGTTTGGCCACGAATCTGTGCGCCAGGCAGCAGAATTGGTGC
GCAATCACGTTGCCGATGCGGTGCAGCAGTCAGCCACTGTTGATCGCTTTCTCGATGACCTCGATGCCATGACTCCCAAG
GGCGCCGACGTTGAGTATCCGTTGTTGGCGAAAATGCGTTCGGCCAGTCGGCGGGCGCTGGTCGACTTGGCGGATCGGTT
CGGTGCCATCGCCAAGAGTCTGGACAATCAAGCGCTATATACTCTTGCCGGCGAACTGGTGTCGGTTGCCAAAATGCTGG
ACCGCGAAATCGTGGTGACTCGGTATCTCACCGTGCCCGTCGAGGATGAGGCGCCCCGGGTCAAGTTGATCGACCGATTG
GTATCCGCCCATGTCGGCGACCCGACGATGGAGATACTGCGGGCGGCCGTATCGGAGCGTTGGTCGGCCAATACCGACCT
GGTCGATGCCCTCGAGCACATCTCGCGCCAAGCGCTATTGGAAGTCGCCGAACGTGAGGACCAGATCGACGAGGTCGAAG
ACCAGGTGTTCCGGTTTTCTCGCATTCTCGACGTTGCGCCGCGACTTGCCATCTTGTTGGATGACTACGCGGTGCCAGCC
GACAGTCGGGTTCGGTTGCTGTGCAATGTGCTGCAGAGCGCGAGTAGCGTGGTCAATCCGATCGCGGTCGCCCTGTTGTC
CCAGACAGTCGAGTTATTAAGAGGTCAGCCGGCCAAGGAAGCCATACTGTTTTTGGCCGAAGTTGCCGTGGCTCGGCGTG
GTGAAGTCGTAGCGCAAGTCAGTGCGGCGGCCGAGATCAGCGATGCCCAGCGCACGCGGCTTACCGAAGTGCTCAGTCGC
ATCTATGGCCATCCCGTGACCGTGCAGATGCAAATCGACGCTGCACTGCTGGGTGGGCTCTCAATCGTGGTGGGTGATGA
GGTGATCGACGGTACTCTCTCGTCTTGTCTGGTCGCCGCTGAGGCTGCGTTGCCCGACTGA

Upstream 100 bases:

>100_bases
AACTGGATCTGCGCGCCAAAGCAGGCGCCATGTCGCTGATCCTGGCCAGTCGAATCCTGGGCGTTGACATCACCGCTTCC
GTTGTGACGAGATAGCGTCA

Downstream 100 bases:

>100_bases
ACACGAACTAGTCACTAAATCCGCGCGAAAGACGAAAATCAAGTAGGAAGACGAAAAAGCCATGGCCGAGTTGACAATCT
CCGCTGACGACATTCAGAAC

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase subunit b; ATP synthase F(0) sector subunit b 2; ATPase subunit I 2; F-type ATPase subunit b 2; F-ATPase subunit b 2; ATP synthase subunit delta; ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSTFIGQLVGFAAIVYLVWWYVVPPVCRLMRARRDAVRQQLTEAAEAADRLVEASQAHTKATEDAKVEAQRVVKEAVEDA
KRIVEQLQAQADVEAERIKLQGARQVELLRAQLTRQLRLKFGHESVRQAAELVRNHVADAVQQSATVDRFLDDLDAMTPK
GADVEYPLLAKMRSASRRALVDLADRFGAIAKSLDNQALYTLAGELVSVAKMLDREIVVTRYLTVPVEDEAPRVKLIDRL
VSAHVGDPTMEILRAAVSERWSANTDLVDALEHISRQALLEVAEREDQIDEVEDQVFRFSRILDVAPRLAILLDDYAVPA
DSRVRLLCNVLQSASSVVNPIAVALLSQTVELLRGQPAKEAILFLAEVAVARRGEVVAQVSAAAEISDAQRTRLTEVLSR
IYGHPVTVQMQIDAALLGGLSIVVGDEVIDGTLSSCLVAAEAALPD

Sequences:

>Translated_446_residues
MSTFIGQLVGFAAIVYLVWWYVVPPVCRLMRARRDAVRQQLTEAAEAADRLVEASQAHTKATEDAKVEAQRVVKEAVEDA
KRIVEQLQAQADVEAERIKLQGARQVELLRAQLTRQLRLKFGHESVRQAAELVRNHVADAVQQSATVDRFLDDLDAMTPK
GADVEYPLLAKMRSASRRALVDLADRFGAIAKSLDNQALYTLAGELVSVAKMLDREIVVTRYLTVPVEDEAPRVKLIDRL
VSAHVGDPTMEILRAAVSERWSANTDLVDALEHISRQALLEVAEREDQIDEVEDQVFRFSRILDVAPRLAILLDDYAVPA
DSRVRLLCNVLQSASSVVNPIAVALLSQTVELLRGQPAKEAILFLAEVAVARRGEVVAQVSAAAEISDAQRTRLTEVLSR
IYGHPVTVQMQIDAALLGGLSIVVGDEVIDGTLSSCLVAAEAALPD
>Mature_445_residues
STFIGQLVGFAAIVYLVWWYVVPPVCRLMRARRDAVRQQLTEAAEAADRLVEASQAHTKATEDAKVEAQRVVKEAVEDAK
RIVEQLQAQADVEAERIKLQGARQVELLRAQLTRQLRLKFGHESVRQAAELVRNHVADAVQQSATVDRFLDDLDAMTPKG
ADVEYPLLAKMRSASRRALVDLADRFGAIAKSLDNQALYTLAGELVSVAKMLDREIVVTRYLTVPVEDEAPRVKLIDRLV
SAHVGDPTMEILRAAVSERWSANTDLVDALEHISRQALLEVAEREDQIDEVEDQVFRFSRILDVAPRLAILLDDYAVPAD
SRVRLLCNVLQSASSVVNPIAVALLSQTVELLRGQPAKEAILFLAEVAVARRGEVVAQVSAAAEISDAQRTRLTEVLSRI
YGHPVTVQMQIDAALLGGLSIVVGDEVIDGTLSSCLVAAEAALPD

Specific function: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral "stator" stalk which links F(1) to F(0)

COG id: COG0711

COG function: function code C; F0F1-type ATP synthase, subunit b

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATPase delta chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPFD_MYCLB (B8ZR39)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503466.1
- ProteinModelPortal:   B8ZR39
- SMR:   B8ZR39
- EnsemblBacteria:   EBMYCT00000085742
- GeneID:   7327250
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016867
- HOGENOM:   HBG566588
- OMA:   YVVPPVR
- ProtClustDB:   PRK13428
- HAMAP:   MF_01398
- HAMAP:   MF_01416
- InterPro:   IPR002146
- InterPro:   IPR000711
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00430 ATP-synt_B; PF00213 OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 48940; Mature: 48808

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00389 ATPASE_DELTA; PS01094 UPF0076

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x297f39f0)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFIGQLVGFAAIVYLVWWYVVPPVCRLMRARRDAVRQQLTEAAEAADRLVEASQAHTK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATEDAKVEAQRVVKEAVEDAKRIVEQLQAQADVEAERIKLQGARQVELLRAQLTRQLRLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
FGHESVRQAAELVRNHVADAVQQSATVDRFLDDLDAMTPKGADVEYPLLAKMRSASRRAL
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VDLADRFGAIAKSLDNQALYTLAGELVSVAKMLDREIVVTRYLTVPVEDEAPRVKLIDRL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHH
VSAHVGDPTMEILRAAVSERWSANTDLVDALEHISRQALLEVAEREDQIDEVEDQVFRFS
HHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILDVAPRLAILLDDYAVPADSRVRLLCNVLQSASSVVNPIAVALLSQTVELLRGQPAKE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AILFLAEVAVARRGEVVAQVSAAAEISDAQRTRLTEVLSRIYGHPVTVQMQIDAALLGGL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCC
SIVVGDEVIDGTLSSCLVAAEAALPD
HHEECCHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
STFIGQLVGFAAIVYLVWWYVVPPVCRLMRARRDAVRQQLTEAAEAADRLVEASQAHTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATEDAKVEAQRVVKEAVEDAKRIVEQLQAQADVEAERIKLQGARQVELLRAQLTRQLRLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
FGHESVRQAAELVRNHVADAVQQSATVDRFLDDLDAMTPKGADVEYPLLAKMRSASRRAL
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VDLADRFGAIAKSLDNQALYTLAGELVSVAKMLDREIVVTRYLTVPVEDEAPRVKLIDRL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHH
VSAHVGDPTMEILRAAVSERWSANTDLVDALEHISRQALLEVAEREDQIDEVEDQVFRFS
HHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILDVAPRLAILLDDYAVPADSRVRLLCNVLQSASSVVNPIAVALLSQTVELLRGQPAKE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AILFLAEVAVARRGEVVAQVSAAAEISDAQRTRLTEVLSRIYGHPVTVQMQIDAALLGGL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCC
SIVVGDEVIDGTLSSCLVAAEAALPD
HHEECCHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA