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The map label for this gene is 221229599

Identifier: 221229599

GI number: 221229599

Start: 492723

End: 493832

Strand: Reverse

Name: 221229599

Synonym: MLBr_00396

Alternate gene names: NA

Gene position: 493832-492723 (Counterclockwise)

Preceding gene: 221229600

Following gene: 221229597

Centisome position: 15.11

GC content: 58.65

Gene sequence:

>1110_bases
ATGAGTGAGCACAACCCAGCAGGGGCGCCAGGGGCGTCGACTGAGGTAAGAGTAGCCATTGTCGGCGTGGGCAACTGCGC
GTCCTCGCTAGTTCAAGGTATCGAGTACTACCAGAACGCTGACGACACATCGACAGTGCCCGGTCTTATGCACGTGCGGT
TCGGACCCTACCATGTGCGTGATGTTAAATTCGTGGCGGCCTTCGACGTAGACGCCAAGAAGGTCGGCGTAGACTTGTCG
GACGCGATCTTCACCTCAGAGAACAACACCATCAAGATCGCCGACGTGCCACCCACCAATGTGGTGGTGCAGCGCGGCCC
AACACTGGACGGCATCGGCAAGTACTACACCGACACCATTGAGCTGTCAGACGTTCCACCCGTCGACGTAGTCCAGGCAC
TAACAGAAGCCAAGACAGACGTGCTGGTGTCCTACCTGCCGGTGGGTTCCGAAGAAGCCGACAAGTTCTATGCCCAGTGC
GCCATCAACGCCCGCGTAGCGTTCGTGAACGCGCTGCCGGTGTTCATCGCCTCCGACCCAGTGTGGGCCAAAAAATTCGC
CGACGCCAGGGTACCGATCGTAGGTGATGACATTAAGAGCCAGGTCGGCGCAACCATCACTCACCGGGTGATGGCCAAGC
TGTTTGAGGACCGCGGGGTGCAGCTGGACCGCACCATGCAACTCAACGTGGGCGGCAACATGGACTTCCTGAATATGCTC
GAGCGCGAACGGGTGCAATCCAAGAAGATCTCCAAGACCCAGGCCGTAACGTCGAACGTGCATCGGGAATTCAATACCAA
AGACATCCACATCGGTCCGTCAGACCACGTCGGCTGGCTCGATGACCGCAAATGGGCCTACGTCCGACTGGAAGGCCGTG
GTTTCGGCGATGTGCCGCTGAACCTCGAATACAAGCTCGAGGTATGGGACTCACCGAACTCAGCGGGCGTCATCATCGAC
GCGGTACGGGCAGCAAAGATAGCCAAGGACCGAGGGATCGGTGGACCAGTGATCCCGGCTTCATCCTACCTGATGAAAAG
CCCGCCGCAACAGCTACCCGACGAGATCGCGCGTGCCCAGCTCGAAGAGTTCATCATCGACACCAAATAA

Upstream 100 bases:

>100_bases
CCGAGTCAGCGGCACTAAAGCCAGTGCGGTCATTCACCCTGCTTAGCTAACTCCCTGTACCAAACAACAAACACCTGAAA
CAAAGTTTTGAGAACGCCCT

Downstream 100 bases:

>100_bases
CGGTTCCGCATTCACCGGCAACCCTGAGCGCCCGAGGAGCGCCAGCGACGTGATGTCATTCCGGAAAGTTTTCGGCGACC
GCTATTCCCACTCGATGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGVDLS
DAIFTSENNTIKIADVPPTNVVVQRGPTLDGIGKYYTDTIELSDVPPVDVVQALTEAKTDVLVSYLPVGSEEADKFYAQC
AINARVAFVNALPVFIASDPVWAKKFADARVPIVGDDIKSQVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNML
ERERVQSKKISKTQAVTSNVHREFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPLNLEYKLEVWDSPNSAGVIID
AVRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIARAQLEEFIIDTK

Sequences:

>Translated_369_residues
MSEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGVDLS
DAIFTSENNTIKIADVPPTNVVVQRGPTLDGIGKYYTDTIELSDVPPVDVVQALTEAKTDVLVSYLPVGSEEADKFYAQC
AINARVAFVNALPVFIASDPVWAKKFADARVPIVGDDIKSQVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNML
ERERVQSKKISKTQAVTSNVHREFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPLNLEYKLEVWDSPNSAGVIID
AVRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIARAQLEEFIIDTK
>Mature_368_residues
SEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGVDLSD
AIFTSENNTIKIADVPPTNVVVQRGPTLDGIGKYYTDTIELSDVPPVDVVQALTEAKTDVLVSYLPVGSEEADKFYAQCA
INARVAFVNALPVFIASDPVWAKKFADARVPIVGDDIKSQVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNMLE
RERVQSKKISKTQAVTSNVHREFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPLNLEYKLEVWDSPNSAGVIIDA
VRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIARAQLEEFIIDTK

Specific function: Unknown

COG id: COG1260

COG function: function code I; Myo-inositol-1-phosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the myo-inositol-1-phosphate synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y396_MYCLE (Q57240)

Other databases:

- EMBL:   U00015
- EMBL:   L39923
- EMBL:   AL583918
- EMBL:   AL583926
- PIR:   S72835
- RefSeq:   NP_301384.1
- RefSeq:   NP_302718.1
- ProteinModelPortal:   Q57240
- SMR:   Q57240
- EnsemblBacteria:   EBMYCT00000028373
- EnsemblBacteria:   EBMYCT00000029017
- GeneID:   908264
- GeneID:   909120
- GenomeReviews:   AL450380_GR
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0396
- KEGG:   mle:ML2692
- Leproma:   ML0396
- Leproma:   ML2692
- GeneTree:   EBGT00050000016696
- HOGENOM:   HBG284345
- OMA:   ASSYFMK
- ProtClustDB:   CLSK2517953
- BioCyc:   MLEP272631:ML0396-MONOMER
- BioCyc:   MLEP272631:ML2692-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002587
- InterPro:   IPR017815
- InterPro:   IPR013021
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11510
- PIRSF:   PIRSF015578
- TIGRFAMs:   TIGR03450

Pfam domain/function: PF01658 Inos-1-P_synth; PF07994 NAD_binding_5

EC number: NA

Molecular weight: Translated: 40278; Mature: 40147

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLMHVRFGPYHVR
CCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEE
DVKFVAAFDVDAKKVGVDLSDAIFTSENNTIKIADVPPTNVVVQRGPTLDGIGKYYTDTI
EEEEEEEECCCHHHHCCCHHHHEEECCCCEEEEEECCCCCEEEECCCCCCCCHHHHCCEE
ELSDVPPVDVVQALTEAKTDVLVSYLPVGSEEADKFYAQCAINARVAFVNALPVFIASDP
EECCCCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHEECCEEEEEEEEEEEEECCC
VWAKKFADARVPIVGDDIKSQVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNML
HHHHHHCCCCCCEECCHHHHHHCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
ERERVQSKKISKTQAVTSNVHREFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCC
NLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIARAQ
EEEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH
LEEFIIDTK
HHHHHCCCC
>Mature Secondary Structure 
SEHNPAGAPGASTEVRVAIVGVGNCASSLVQGIEYYQNADDTSTVPGLMHVRFGPYHVR
CCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEE
DVKFVAAFDVDAKKVGVDLSDAIFTSENNTIKIADVPPTNVVVQRGPTLDGIGKYYTDTI
EEEEEEEECCCHHHHCCCHHHHEEECCCCEEEEEECCCCCEEEECCCCCCCCHHHHCCEE
ELSDVPPVDVVQALTEAKTDVLVSYLPVGSEEADKFYAQCAINARVAFVNALPVFIASDP
EECCCCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHEECCEEEEEEEEEEEEECCC
VWAKKFADARVPIVGDDIKSQVGATITHRVMAKLFEDRGVQLDRTMQLNVGGNMDFLNML
HHHHHHCCCCCCEECCHHHHHHCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
ERERVQSKKISKTQAVTSNVHREFNTKDIHIGPSDHVGWLDDRKWAYVRLEGRGFGDVPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCC
NLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVIPASSYLMKSPPQQLPDEIARAQ
EEEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH
LEEFIIDTK
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969512; 11234002