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The map label for this gene is yafC [H]

Identifier: 220918753

GI number: 220918753

Start: 4082623

End: 4083576

Strand: Direct

Name: yafC [H]

Synonym: A2cp1_3664

Alternate gene names: 220918753

Gene position: 4082623-4083576 (Clockwise)

Preceding gene: 220918747

Following gene: 220918754

Centisome position: 81.18

GC content: 77.78

Gene sequence:

>954_bases
ATGGCCCATGGCGACGGCAACCGGCTGTACGAGATGGAGGCGTTCGCGGCCGTCGCGGAGCTGGGCGGCTTCTCCGCCGC
CGGGCGCGCGCTCGGGAAGACCCCCTCCGCGCTGAACAAGCTGGTCGCGCGCCTCGAGGCGCGGCTCGGGGCGCGGCTGC
TCACGCGCACCACGCGCGCGGTCCGGCTCACCGCCGAGGGCGAGGCGTTTCACCAGCGGGCGCTCCGGATCCTGGCGGAG
GTGGAGGAGGCCGAGAGCGAGGCACGGGGCGGCGCGCCGCGCGGCCGGGTGCGCGTGAACGCGAACCTCCCGTTCGGCGT
GCACTGCCTGCTGCCGGTGGTGCGGAGCTTCCTCGAGGCGAACCCGGGCGTCACGCTCGACCTGGTGCTCACCGACGAGG
TGGTCGACCTGGTGGAGCGGCGCGCCGACGTCGCCATCCGCGTGGGCCCGCTGCGCGCCTCCGGGCTGCTCGCGCGCAAG
CTGGGCGAGAGCCCGGTGGCCGTGGTCGCGTCACCCGACTACCTCGCGCGCCGCGGGACGCCGCACACGCCGGCCGACCT
CGGCGCGCACGAGCGGATCGGCTTCACGTTCGCGCGCACCCTCCAGGACTGGCCGTTCCGCCAGGGCGGCGAGGAGGTGC
GGGTGCCGGTGCGCGGCGCCGTGCGCGCGGGCGACGGCGAGACTGCGCGGCGGCTGGCGCTCGCGGGCGCGGGCCTCGCG
CGCCTCGCGCTCTTCCAGGTCACGGACGACCTCGAGGCAGGGCGCCTCGTGCGCGTCCTCGAGGCGTTCGAGCCCGGAGA
CGCCCTCGAGATCCACGCGCTGTTCCTGGGCCCCGCCGGCTCGGTGCCGGCGCGGGTCCGCGCGTTCGTGGAGTTCCTCG
CATCCGCCCTGGGCAGCGGGCGCGGCGCCGGGGCGCGGGCCGGCCGCTCTCGCGAGGGGGCGTCGGGGCGGTGA

Upstream 100 bases:

>100_bases
CGAGCCCTGGCCGGCCTGCGCGTCGCGCGGAAAGGATGCGCGGCGCCCCCCCTCCCCGCTAGCACTCTCCAGGCACAACA
CCTGTGAACCGAGCTCATCG

Downstream 100 bases:

>100_bases
ACCGGCCCGGGGCGCGGCCGGCGGCGCGAGCAGGCCGCTGCACCGGGCGCGTTTGACACGGCCGGCGTCGGACGCATGTT
CTGCTCATGGCCTCGCCCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAHGDGNRLYEMEAFAAVAELGGFSAAGRALGKTPSALNKLVARLEARLGARLLTRTTRAVRLTAEGEAFHQRALRILAE
VEEAESEARGGAPRGRVRVNANLPFGVHCLLPVVRSFLEANPGVTLDLVLTDEVVDLVERRADVAIRVGPLRASGLLARK
LGESPVAVVASPDYLARRGTPHTPADLGAHERIGFTFARTLQDWPFRQGGEEVRVPVRGAVRAGDGETARRLALAGAGLA
RLALFQVTDDLEAGRLVRVLEAFEPGDALEIHALFLGPAGSVPARVRAFVEFLASALGSGRGAGARAGRSREGASGR

Sequences:

>Translated_317_residues
MAHGDGNRLYEMEAFAAVAELGGFSAAGRALGKTPSALNKLVARLEARLGARLLTRTTRAVRLTAEGEAFHQRALRILAE
VEEAESEARGGAPRGRVRVNANLPFGVHCLLPVVRSFLEANPGVTLDLVLTDEVVDLVERRADVAIRVGPLRASGLLARK
LGESPVAVVASPDYLARRGTPHTPADLGAHERIGFTFARTLQDWPFRQGGEEVRVPVRGAVRAGDGETARRLALAGAGLA
RLALFQVTDDLEAGRLVRVLEAFEPGDALEIHALFLGPAGSVPARVRAFVEFLASALGSGRGAGARAGRSREGASGR
>Mature_316_residues
AHGDGNRLYEMEAFAAVAELGGFSAAGRALGKTPSALNKLVARLEARLGARLLTRTTRAVRLTAEGEAFHQRALRILAEV
EEAESEARGGAPRGRVRVNANLPFGVHCLLPVVRSFLEANPGVTLDLVLTDEVVDLVERRADVAIRVGPLRASGLLARKL
GESPVAVVASPDYLARRGTPHTPADLGAHERIGFTFARTLQDWPFRQGGEEVRVPVRGAVRAGDGETARRLALAGAGLAR
LALFQVTDDLEAGRLVRVLEAFEPGDALEIHALFLGPAGSVPARVRAFVEFLASALGSGRGAGARAGRSREGASGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=36.9127516778523, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=30.7958477508651, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1787589, Length=260, Percent_Identity=33.0769230769231, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI145693193, Length=304, Percent_Identity=30.2631578947368, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=31.864406779661, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789440, Length=307, Percent_Identity=27.3615635179153, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=29.0102389078498, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789173, Length=246, Percent_Identity=27.6422764227642, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790262, Length=196, Percent_Identity=27.0408163265306, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI157672245, Length=191, Percent_Identity=29.3193717277487, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788706, Length=221, Percent_Identity=22.1719457013575, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33505; Mature: 33374

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHGDGNRLYEMEAFAAVAELGGFSAAGRALGKTPSALNKLVARLEARLGARLLTRTTRA
CCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
VRLTAEGEAFHQRALRILAEVEEAESEARGGAPRGRVRVNANLPFGVHCLLPVVRSFLEA
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHC
NPGVTLDLVLTDEVVDLVERRADVAIRVGPLRASGLLARKLGESPVAVVASPDYLARRGT
CCCCEEEEEECHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEECCHHHHHCCC
PHTPADLGAHERIGFTFARTLQDWPFRQGGEEVRVPVRGAVRAGDGETARRLALAGAGLA
CCCCHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHCCCHH
RLALFQVTDDLEAGRLVRVLEAFEPGDALEIHALFLGPAGSVPARVRAFVEFLASALGSG
HHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
RGAGARAGRSREGASGR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AHGDGNRLYEMEAFAAVAELGGFSAAGRALGKTPSALNKLVARLEARLGARLLTRTTRA
CCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
VRLTAEGEAFHQRALRILAEVEEAESEARGGAPRGRVRVNANLPFGVHCLLPVVRSFLEA
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHC
NPGVTLDLVLTDEVVDLVERRADVAIRVGPLRASGLLARKLGESPVAVVASPDYLARRGT
CCCCEEEEEECHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEECCHHHHHCCC
PHTPADLGAHERIGFTFARTLQDWPFRQGGEEVRVPVRGAVRAGDGETARRLALAGAGLA
CCCCHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHCCCHH
RLALFQVTDDLEAGRLVRVLEAFEPGDALEIHALFLGPAGSVPARVRAFVEFLASALGSG
HHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
RGAGARAGRSREGASGR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]