Click here to switch to the map view.

The map label for this gene is pheS [H]

Identifier: 220918674

GI number: 220918674

Start: 4000339

End: 4001475

Strand: Direct

Name: pheS [H]

Synonym: A2cp1_3582

Alternate gene names: 220918674

Gene position: 4000339-4001475 (Clockwise)

Preceding gene: 220918673

Following gene: 220918675

Centisome position: 79.54

GC content: 76.96

Gene sequence:

>1137_bases
ATGTCGAAGCTCCCCGTCCTGTCCCCCGGCGCGCTGGAACGCGCGCTCGCCCTCCGCGATCTCACCGACCCGGCGCAGGG
GCCGCACGCCGTGCAGCTCGTGCTGCGCAAGGTGGTGGACGCGCTCTCCGGCGCCTGGCGCTGCCCGGTCGCCGTCGAGC
GCGCCAGCCCGGTGGTCGCGGTCGCCGACAACTACGACCGGCTCCACTACCCGCCCGGCGGCGCGGCCCGCGACGCGCGC
CACACCCGCTACGTCTCCGACACGCACCTGCTCCGCACCCAGACCACCGCCCTGGTGCCGCCGGCGCTCCGCAGGCTCGC
CGCGGCGCCGCCGCAGGACGTGCTGCTGGTCTGCCCGGGCATGGTGTACCGGCGCGACGCCATCGACCGCCTCCACACCG
GCGAGCCGCACCAGGTGGATCTGTGGCGGATCCGCCGCGGCCCGCCGCTCGGCGTGCACGAGCTGGCGGAGATGATCGCC
GGCGCGGTCCGGGCGGTGCTGCCCGAGCTCACGCTCTCCGTGGTGCCATCGCCGCACCCGTACACGCGCGAGGGCCGCCA
GATCGACGTCCGCGTGCGCGGCGAGTGGATCGAGATCGGCGAGTGCGGCCTCGTCACGCCCGAGGTGCTCGCCGAGGCCG
GGCTGCCCGAGGACGCGAGCGGGCTCGCCATGGGGCTCGGGCTCGACCGCCTGGTGATGCTGGCGAAGGGGCTCGACGAC
ATCCGCCTGCTCCGCTCCGACGACCCGCGCATCGCGGCCCAGATGCAGGACCTCTCGCCGTGGCGGCCGGTGTCGCGCCA
CCCGCCGATGCGCCGCGACCTCTCGGTGGCGGTGGCGGCGGACGCGGGCGCGGAGGCGCTCGGCGACCGCGTGCGCGAGG
CGCTCGGGCCGCGCGCCGCCGACGTCGAGGACATCGAGGTCCGGTCGGAGACGCCCTGGGAGGCGCTGCCGGAGTCGGCC
CGGGCGCGGCTGGGGATGCGCCCGGGACAGAAGAACGTGCTGCTCCGGCTCGTGCTGCGCGCGCTGGGGCGGACGCTCAC
CGACGACGAGGCCAACCGGCTCCGCGACGCCGTCTACGCCGCGGTGCACGAGGGCACCGAGCACGCCTGGGCCTGCGGCG
CGGTCCCCGCCTCCTAG

Upstream 100 bases:

>100_bases
CGAGATCGTTCGGGCCGTGGCGGGGGGAGTCGTCGCTCCACCCTTCCATCCACGGGCGCGCCCGCCGCGCGGCGCGCCGC
CGCCTCTCGAGGTCCGAACC

Downstream 100 bases:

>100_bases
CTTCCGCCCCCGGCGGGGGTGCGGAGGCCCGCGGGCACCCCGCGCCCCGGCCCGGGGCTATCCTGGGAGGTGACGTCCCC
CGGGAGGCCACGCCGTGCGA

Product: phenylalanyl-tRNA synthetase class IIc

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSKLPVLSPGALERALALRDLTDPAQGPHAVQLVLRKVVDALSGAWRCPVAVERASPVVAVADNYDRLHYPPGGAARDAR
HTRYVSDTHLLRTQTTALVPPALRRLAAAPPQDVLLVCPGMVYRRDAIDRLHTGEPHQVDLWRIRRGPPLGVHELAEMIA
GAVRAVLPELTLSVVPSPHPYTREGRQIDVRVRGEWIEIGECGLVTPEVLAEAGLPEDASGLAMGLGLDRLVMLAKGLDD
IRLLRSDDPRIAAQMQDLSPWRPVSRHPPMRRDLSVAVAADAGAEALGDRVREALGPRAADVEDIEVRSETPWEALPESA
RARLGMRPGQKNVLLRLVLRALGRTLTDDEANRLRDAVYAAVHEGTEHAWACGAVPAS

Sequences:

>Translated_378_residues
MSKLPVLSPGALERALALRDLTDPAQGPHAVQLVLRKVVDALSGAWRCPVAVERASPVVAVADNYDRLHYPPGGAARDAR
HTRYVSDTHLLRTQTTALVPPALRRLAAAPPQDVLLVCPGMVYRRDAIDRLHTGEPHQVDLWRIRRGPPLGVHELAEMIA
GAVRAVLPELTLSVVPSPHPYTREGRQIDVRVRGEWIEIGECGLVTPEVLAEAGLPEDASGLAMGLGLDRLVMLAKGLDD
IRLLRSDDPRIAAQMQDLSPWRPVSRHPPMRRDLSVAVAADAGAEALGDRVREALGPRAADVEDIEVRSETPWEALPESA
RARLGMRPGQKNVLLRLVLRALGRTLTDDEANRLRDAVYAAVHEGTEHAWACGAVPAS
>Mature_377_residues
SKLPVLSPGALERALALRDLTDPAQGPHAVQLVLRKVVDALSGAWRCPVAVERASPVVAVADNYDRLHYPPGGAARDARH
TRYVSDTHLLRTQTTALVPPALRRLAAAPPQDVLLVCPGMVYRRDAIDRLHTGEPHQVDLWRIRRGPPLGVHELAEMIAG
AVRAVLPELTLSVVPSPHPYTREGRQIDVRVRGEWIEIGECGLVTPEVLAEAGLPEDASGLAMGLGLDRLVMLAKGLDDI
RLLRSDDPRIAAQMQDLSPWRPVSRHPPMRRDLSVAVAADAGAEALGDRVREALGPRAADVEDIEVRSETPWEALPESAR
ARLGMRPGQKNVLLRLVLRALGRTLTDDEANRLRDAVYAAVHEGTEHAWACGAVPAS

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=186, Percent_Identity=30.6451612903226, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788007, Length=196, Percent_Identity=33.1632653061224, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32566635, Length=408, Percent_Identity=25, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17508957, Length=225, Percent_Identity=28, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563657, Length=223, Percent_Identity=27.8026905829596, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325304, Length=214, Percent_Identity=28.5046728971963, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17137424, Length=400, Percent_Identity=24.25, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18858079, Length=176, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 41071; Mature: 40939

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLPVLSPGALERALALRDLTDPAQGPHAVQLVLRKVVDALSGAWRCPVAVERASPVVA
CCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEE
VADNYDRLHYPPGGAARDARHTRYVSDTHLLRTQTTALVPPALRRLAAAPPQDVLLVCPG
EECCCCEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCC
MVYRRDAIDRLHTGEPHQVDLWRIRRGPPLGVHELAEMIAGAVRAVLPELTLSVVPSPHP
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YTREGRQIDVRVRGEWIEIGECGLVTPEVLAEAGLPEDASGLAMGLGLDRLVMLAKGLDD
CCCCCCEEEEEEECCEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCHHHHHHHHCCCHH
IRLLRSDDPRIAAQMQDLSPWRPVSRHPPMRRDLSVAVAADAGAEALGDRVREALGPRAA
HHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
DVEDIEVRSETPWEALPESARARLGMRPGQKNVLLRLVLRALGRTLTDDEANRLRDAVYA
CCCCEEECCCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVHEGTEHAWACGAVPAS
HHHCCCCCCEECCCCCCC
>Mature Secondary Structure 
SKLPVLSPGALERALALRDLTDPAQGPHAVQLVLRKVVDALSGAWRCPVAVERASPVVA
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEE
VADNYDRLHYPPGGAARDARHTRYVSDTHLLRTQTTALVPPALRRLAAAPPQDVLLVCPG
EECCCCEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCC
MVYRRDAIDRLHTGEPHQVDLWRIRRGPPLGVHELAEMIAGAVRAVLPELTLSVVPSPHP
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YTREGRQIDVRVRGEWIEIGECGLVTPEVLAEAGLPEDASGLAMGLGLDRLVMLAKGLDD
CCCCCCEEEEEEECCEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCHHHHHHHHCCCHH
IRLLRSDDPRIAAQMQDLSPWRPVSRHPPMRRDLSVAVAADAGAEALGDRVREALGPRAA
HHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCC
DVEDIEVRSETPWEALPESARARLGMRPGQKNVLLRLVLRALGRTLTDDEANRLRDAVYA
CCCCEEECCCCCHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVHEGTEHAWACGAVPAS
HHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA