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The map label for this gene is aidB [H]

Identifier: 220918318

GI number: 220918318

Start: 3579045

End: 3580724

Strand: Direct

Name: aidB [H]

Synonym: A2cp1_3222

Alternate gene names: 220918318

Gene position: 3579045-3580724 (Clockwise)

Preceding gene: 220918316

Following gene: 220918320

Centisome position: 71.16

GC content: 77.92

Gene sequence:

>1680_bases
ATGACCGCCTTCCATCAGGATCCCCCGATCCTGCCGCACGCCTTCGACGCCGACCCGCTCCTGCAGGAGTATCTCGCGAG
GACGCTGCCGCCCGAGGTCCTGTCCGAGATCTCGCCGGAGCTGCGCGAGCTTGGCGCGCTCGCATCGGGCCCGCTCGCGG
CGCAGCAGCTCGCCGAGCGGCTGGTGGAGCCCACCCTGGTGCAGTGGGATCCCTGGGGGCGCCGCGTGGACCGCATCGAG
CCCACGCCGCTCTGGCGCGAGGCGGCCCGGCTCGCCGCACGCCACGGGCTCGTGGCCGCGGCCTACGAGCGGCGCCACGG
CATCCTCTCGCGCGTGCACCAGATGGCCATGGTGTACCTGCTCGAGCCCTCGATGGACGTGTACGCGTGCCCGCTCGCCA
TGACGGACGGCGCGGCGCGCACGCTGCTCGACCTCGCCCCGCGCGCGCTGGTGGAGCGGGCCGTCCCGCGGCTCACCTCC
CGCGATCCGGCGCGCACGTGGACGAGCGGCCAGTGGATGACCGAGCGCGCCGGCGGCTCCGACGTGTCCGGGACCGAGAC
GGTGGCCCGCCCCGACGGCGAGGCGTTCCGGCTCTGGGGCACGAAGTGGTTCAGCTCCGCCACGACCGCGGAGATGGCGC
TCGCCCTGGCGCGCCCCGAGGGCAACCCGCCCGGCTCGGCGGGCCTGGCCCTGTTCTACCTGGAGACGCGCTTGCCGGAC
GGCGCGTCCAACGGGATCCTGGTGAACCGGCTGAAGGACAAGCTCGGCACGCGCAAGCTCCCCACGGCCGAGCTGACGCT
GGACGGGGCGCTGGCGCTCCCGGTGGTGGGGCTCTCCGGCGGCGTGCGCGCGATCAGCCCCATGCTGAACGTGACCCGCA
CCTGGAACGCGCTCGTCGCGGCCGCGTACATGGCGCGCGCGGTGGCGCTGGCGCGCGACTACGCCGGGCGGCGGCGCGCC
TTCGGGACGCCGCTGCGGGCGCGCCCGCTCCACGCCGACACCCTGGCGGCGCTCGAGGCCGAGCGCGAGGCCGGGTTCCT
GCTCGCGTTCCGCGCGGTGGAGCTGCTCGGGCGCGCCGAGGCGGGCGAGGCCGATGCGGGCGCGCGCGCGCTGCTCCGCG
CGGTGACGCCGCTCGCGAAGCTCACCACCGGGAAGCAGGCGGTGGCGGTCGCCTCGGACGCGATCGAGGCGTTCGGCGGC
GCCGGCTACGTGGAGGACACCGGCCTGCCGCGCCTGCTCCGCGACGCGCAGGTGCTGCCGATCTGGGAGGGGACCACGAA
CGTCCTCGCGCTCGAGGCGCAGCGCGCGCTCGCCGCCGAGGGCGCGGCCGAGGCGCTCGCGGCGGAGATCCAGGAGCGGC
TCTCGCAGGCGCGCGACCCGGCGCTCCGCCCGGCGGTGCAGGCCGCCACCGGCGCGCTCGCCCGGGCGCGGGCCGCGCTC
GCGGCGGGCGACGCGCCGGAGGTGCGGGAGGCGGGAGCGCGCCGGCTGGCGCTCACGCTGGGACGGACGCTGGCGCTCGC
CCACCTCGCCGCGCACGCGCAGTGGGCCCTCGACGCCGGGCGCGGGCGCCGGGCGACGGCCGCGGCGCGGCGGTTCGCCC
GCAACGGCGTGGACCTGCTCGGCCCCGCCGGCGAGGACCTGGAGGACTCGGCGCTGCTCGTCGCCGCGCCCGACGCCTGA

Upstream 100 bases:

>100_bases
CCGGCTCGCCCGGGGTGGATCGGGTTCCTTTCGGGCGCGCGCAGAGGGGGCGTCCGGGCCTGGCGCTGCCCCGCGGGCCG
TGCGGCGTTATCGGCTCGGG

Downstream 100 bases:

>100_bases
CGGCTACTCCATGGCCGCGCCGGGCTGCCCCGCCGCCGCGGCGGCGTCCTGCAGCACGACCGTCTTCAGGTTCACGAACT
CGCGGATGCCCTCGCGCGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MTAFHQDPPILPHAFDADPLLQEYLARTLPPEVLSEISPELRELGALASGPLAAQQLAERLVEPTLVQWDPWGRRVDRIE
PTPLWREAARLAARHGLVAAAYERRHGILSRVHQMAMVYLLEPSMDVYACPLAMTDGAARTLLDLAPRALVERAVPRLTS
RDPARTWTSGQWMTERAGGSDVSGTETVARPDGEAFRLWGTKWFSSATTAEMALALARPEGNPPGSAGLALFYLETRLPD
GASNGILVNRLKDKLGTRKLPTAELTLDGALALPVVGLSGGVRAISPMLNVTRTWNALVAAAYMARAVALARDYAGRRRA
FGTPLRARPLHADTLAALEAEREAGFLLAFRAVELLGRAEAGEADAGARALLRAVTPLAKLTTGKQAVAVASDAIEAFGG
AGYVEDTGLPRLLRDAQVLPIWEGTTNVLALEAQRALAAEGAAEALAAEIQERLSQARDPALRPAVQAATGALARARAAL
AAGDAPEVREAGARRLALTLGRTLALAHLAAHAQWALDAGRGRRATAAARRFARNGVDLLGPAGEDLEDSALLVAAPDA

Sequences:

>Translated_559_residues
MTAFHQDPPILPHAFDADPLLQEYLARTLPPEVLSEISPELRELGALASGPLAAQQLAERLVEPTLVQWDPWGRRVDRIE
PTPLWREAARLAARHGLVAAAYERRHGILSRVHQMAMVYLLEPSMDVYACPLAMTDGAARTLLDLAPRALVERAVPRLTS
RDPARTWTSGQWMTERAGGSDVSGTETVARPDGEAFRLWGTKWFSSATTAEMALALARPEGNPPGSAGLALFYLETRLPD
GASNGILVNRLKDKLGTRKLPTAELTLDGALALPVVGLSGGVRAISPMLNVTRTWNALVAAAYMARAVALARDYAGRRRA
FGTPLRARPLHADTLAALEAEREAGFLLAFRAVELLGRAEAGEADAGARALLRAVTPLAKLTTGKQAVAVASDAIEAFGG
AGYVEDTGLPRLLRDAQVLPIWEGTTNVLALEAQRALAAEGAAEALAAEIQERLSQARDPALRPAVQAATGALARARAAL
AAGDAPEVREAGARRLALTLGRTLALAHLAAHAQWALDAGRGRRATAAARRFARNGVDLLGPAGEDLEDSALLVAAPDA
>Mature_558_residues
TAFHQDPPILPHAFDADPLLQEYLARTLPPEVLSEISPELRELGALASGPLAAQQLAERLVEPTLVQWDPWGRRVDRIEP
TPLWREAARLAARHGLVAAAYERRHGILSRVHQMAMVYLLEPSMDVYACPLAMTDGAARTLLDLAPRALVERAVPRLTSR
DPARTWTSGQWMTERAGGSDVSGTETVARPDGEAFRLWGTKWFSSATTAEMALALARPEGNPPGSAGLALFYLETRLPDG
ASNGILVNRLKDKLGTRKLPTAELTLDGALALPVVGLSGGVRAISPMLNVTRTWNALVAAAYMARAVALARDYAGRRRAF
GTPLRARPLHADTLAALEAEREAGFLLAFRAVELLGRAEAGEADAGARALLRAVTPLAKLTTGKQAVAVASDAIEAFGGA
GYVEDTGLPRLLRDAQVLPIWEGTTNVLALEAQRALAAEGAAEALAAEIQERLSQARDPALRPAVQAATGALARARAALA
AGDAPEVREAGARRLALTLGRTLALAHLAAHAQWALDAGRGRRATAAARRFARNGVDLLGPAGEDLEDSALLVAAPDA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=288, Percent_Identity=28.125, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI7656849, Length=389, Percent_Identity=24.1645244215938, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI187960098, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557231, Length=266, Percent_Identity=27.8195488721804, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557235, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI226958412, Length=295, Percent_Identity=25.7627118644068, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI226958414, Length=295, Percent_Identity=25.7627118644068, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI76496475, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082384, Length=400, Percent_Identity=33.75, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081958, Length=271, Percent_Identity=28.7822878228782, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=528, Percent_Identity=41.6666666666667, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI86563381, Length=528, Percent_Identity=41.6666666666667, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17533517, Length=390, Percent_Identity=25.3846153846154, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=273, Percent_Identity=29.3040293040293, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=270, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=269, Percent_Identity=27.1375464684015, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=276, Percent_Identity=28.9855072463768, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=298, Percent_Identity=24.496644295302, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356377, Length=278, Percent_Identity=28.0575539568345, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=284, Percent_Identity=28.8732394366197, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363737, Length=270, Percent_Identity=27.037037037037, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666513, Length=290, Percent_Identity=26.8965517241379, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646207, Length=282, Percent_Identity=28.0141843971631, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59291; Mature: 59160

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFHQDPPILPHAFDADPLLQEYLARTLPPEVLSEISPELRELGALASGPLAAQQLAER
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
LVEPTLVQWDPWGRRVDRIEPTPLWREAARLAARHGLVAAAYERRHGILSRVHQMAMVYL
HCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LEPSMDVYACPLAMTDGAARTLLDLAPRALVERAVPRLTSRDPARTWTSGQWMTERAGGS
CCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
DVSGTETVARPDGEAFRLWGTKWFSSATTAEMALALARPEGNPPGSAGLALFYLETRLPD
CCCCCCCCCCCCCCEEEEECHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
GASNGILVNRLKDKLGTRKLPTAELTLDGALALPVVGLSGGVRAISPMLNVTRTWNALVA
CCCCCEEHHHHHHHHCCCCCCCCEEEECCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHH
AAYMARAVALARDYAGRRRAFGTPLRARPLHADTLAALEAEREAGFLLAFRAVELLGRAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
AGEADAGARALLRAVTPLAKLTTGKQAVAVASDAIEAFGGAGYVEDTGLPRLLRDAQVLP
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEE
IWEGTTNVLALEAQRALAAEGAAEALAAEIQERLSQARDPALRPAVQAATGALARARAAL
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AAGDAPEVREAGARRLALTLGRTLALAHLAAHAQWALDAGRGRRATAAARRFARNGVDLL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
GPAGEDLEDSALLVAAPDA
CCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
TAFHQDPPILPHAFDADPLLQEYLARTLPPEVLSEISPELRELGALASGPLAAQQLAER
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
LVEPTLVQWDPWGRRVDRIEPTPLWREAARLAARHGLVAAAYERRHGILSRVHQMAMVYL
HCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LEPSMDVYACPLAMTDGAARTLLDLAPRALVERAVPRLTSRDPARTWTSGQWMTERAGGS
CCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCC
DVSGTETVARPDGEAFRLWGTKWFSSATTAEMALALARPEGNPPGSAGLALFYLETRLPD
CCCCCCCCCCCCCCEEEEECHHHHCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
GASNGILVNRLKDKLGTRKLPTAELTLDGALALPVVGLSGGVRAISPMLNVTRTWNALVA
CCCCCEEHHHHHHHHCCCCCCCCEEEECCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHH
AAYMARAVALARDYAGRRRAFGTPLRARPLHADTLAALEAEREAGFLLAFRAVELLGRAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
AGEADAGARALLRAVTPLAKLTTGKQAVAVASDAIEAFGGAGYVEDTGLPRLLRDAQVLP
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEE
IWEGTTNVLALEAQRALAAEGAAEALAAEIQERLSQARDPALRPAVQAATGALARARAAL
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AAGDAPEVREAGARRLALTLGRTLALAHLAAHAQWALDAGRGRRATAAARRFARNGVDLL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
GPAGEDLEDSALLVAAPDA
CCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]