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The map label for this gene is ribD [H]

Identifier: 220918025

GI number: 220918025

Start: 3239491

End: 3240669

Strand: Reverse

Name: ribD [H]

Synonym: A2cp1_2926

Alternate gene names: 220918025

Gene position: 3240669-3239491 (Counterclockwise)

Preceding gene: 220918026

Following gene: 220918024

Centisome position: 64.44

GC content: 79.47

Gene sequence:

>1179_bases
GTGACCGCACGCGCGGCGCCGTCGGGGTGGCGGGCGAGCGCCCGCGCGCCCGCGCCCGTCGCCGGCGCGGAGGCGGAGCG
CTTCATGCGCCTGGCCGTGCGCGAGGCGGCGCGCGGGCTGGGGCGCACCAGCCCGAACCCCGCGGTGGGCGCGGTGGTGG
TCCGCGACGGGCGCGTGGTCGGGCGAGGCCACCACGCGCGCGCCGGCGGGCCGCACGCCGAGGTGGTGGCGCTCCGGGCC
GCCGGGGCGCTGGCGCGCGGGGCGGACGTGTACACCACGCTCGAGCCCTGCGATCACTTCGGCAAGACGCCGCCCTGCTC
GGTGGCGCTGCTCGAGGCCGGGGTGCGGCGGGTGTTCGTGGGCTCGAGCGACCCGAACCCGCTGGTGAACGGGCGCGGGA
TGGCCCGGCTCCGCCGGCACGGCGTGGCGGTGGTGAAGGGCGTGCTGCGCGACGCGTGCGACCGCCTCAACGCGCCCTGG
TTCACGTTCATCACCGAGGGTCGGCCGTTCGTGACGCTGAAGGCGGCGGTGACGCTCGACGGCCGCATCGCCACCCGCAC
CGGCGACGCGCGCTGGGTGAGCGGCGAGGCGGCGCGCGCCTGGGTGCACCGGCTCCGCGACCGGGTGGACGCGGTGCTGG
TGGGCGCCGGGACGGCCCGGGCCGACGACCCGCGGCTCACCACGCGCCTGCCGCGCGGCGGCCGCGACCCGATCCGCGTC
GTGCTCGACAGCGATCTCTCGCTGCCGCGGACGCTGGCGCTGTTCCGCGGCGGCTCGCCGGCCCCGACGCTCGTGGCGCA
CGCGTCTGCCGCGCCGGCGCGCCGGTACGGGCCCGGCGTGGAGCTCGTGCGCTGCCGCCGCGGGAAGGGCGGGGTGGACC
TGCGGGACCTGCTCGCGAAGCTCGCCGCGCGCGGCGTCGCGCACCTGCTCGTGGAGGGCGGCGCGCACGTCCACGCGCGC
TTCCTCGAGGCCGGCCTGGTGGACCGGGTGGCCGTCTTCGTCGCGCCGAAGATCGCGGGCGGGGACGGCGTGCCGCTCGT
GGCGGGCCGCGGGCCGGCGCGGATGGCGGACGCGCTGCGCCTGGAGCAGGTGGCGTTCGAGCGGGTGGGCGACGACCTGC
TCGTCACGGGCGTCCCCGCGCGCCGCGCCGCGTTGGCCAAAAACCCCCAACGAGGCTAG

Upstream 100 bases:

>100_bases
TCGCCTACGTGCGCTTCGCCTCGGTGTACCGGGCCTTTCGCGACGTGGGCGAGTTCATGACCGAGCTGGCCGGGCTGGCG
CGGAAGGACGGGGAGGAGCG

Downstream 100 bases:

>100_bases
GATTCGCGCGAAATGTTCACCGGACTCGTCGCCGACGTCGGCGTGGTGGAGCGGATCGTCCCCCGGCAGGGAGGCGCTCG
CCTGACGCTCCGCCCGGCGC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTARAAPSGWRASARAPAPVAGAEAERFMRLAVREAARGLGRTSPNPAVGAVVVRDGRVVGRGHHARAGGPHAEVVALRA
AGALARGADVYTTLEPCDHFGKTPPCSVALLEAGVRRVFVGSSDPNPLVNGRGMARLRRHGVAVVKGVLRDACDRLNAPW
FTFITEGRPFVTLKAAVTLDGRIATRTGDARWVSGEAARAWVHRLRDRVDAVLVGAGTARADDPRLTTRLPRGGRDPIRV
VLDSDLSLPRTLALFRGGSPAPTLVAHASAAPARRYGPGVELVRCRRGKGGVDLRDLLAKLAARGVAHLLVEGGAHVHAR
FLEAGLVDRVAVFVAPKIAGGDGVPLVAGRGPARMADALRLEQVAFERVGDDLLVTGVPARRAALAKNPQRG

Sequences:

>Translated_392_residues
MTARAAPSGWRASARAPAPVAGAEAERFMRLAVREAARGLGRTSPNPAVGAVVVRDGRVVGRGHHARAGGPHAEVVALRA
AGALARGADVYTTLEPCDHFGKTPPCSVALLEAGVRRVFVGSSDPNPLVNGRGMARLRRHGVAVVKGVLRDACDRLNAPW
FTFITEGRPFVTLKAAVTLDGRIATRTGDARWVSGEAARAWVHRLRDRVDAVLVGAGTARADDPRLTTRLPRGGRDPIRV
VLDSDLSLPRTLALFRGGSPAPTLVAHASAAPARRYGPGVELVRCRRGKGGVDLRDLLAKLAARGVAHLLVEGGAHVHAR
FLEAGLVDRVAVFVAPKIAGGDGVPLVAGRGPARMADALRLEQVAFERVGDDLLVTGVPARRAALAKNPQRG
>Mature_391_residues
TARAAPSGWRASARAPAPVAGAEAERFMRLAVREAARGLGRTSPNPAVGAVVVRDGRVVGRGHHARAGGPHAEVVALRAA
GALARGADVYTTLEPCDHFGKTPPCSVALLEAGVRRVFVGSSDPNPLVNGRGMARLRRHGVAVVKGVLRDACDRLNAPWF
TFITEGRPFVTLKAAVTLDGRIATRTGDARWVSGEAARAWVHRLRDRVDAVLVGAGTARADDPRLTTRLPRGGRDPIRVV
LDSDLSLPRTLALFRGGSPAPTLVAHASAAPARRYGPGVELVRCRRGKGGVDLRDLLAKLAARGVAHLLVEGGAHVHARF
LEAGLVDRVAVFVAPKIAGGDGVPLVAGRGPARMADALRLEQVAFERVGDDLLVTGVPARRAALAKNPQRG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=364, Percent_Identity=37.9120879120879, Blast_Score=237, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41140; Mature: 41009

Theoretical pI: Translated: 11.98; Mature: 11.98

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARAAPSGWRASARAPAPVAGAEAERFMRLAVREAARGLGRTSPNPAVGAVVVRDGRVV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEE
GRGHHARAGGPHAEVVALRAAGALARGADVYTTLEPCDHFGKTPPCSVALLEAGVRRVFV
ECCCCCCCCCCCHHEEEEEHHHHHHCCCCEEEECHHHHHCCCCCCHHHHHHHHCCCEEEE
GSSDPNPLVNGRGMARLRRHGVAVVKGVLRDACDRLNAPWFTFITEGRPFVTLKAAVTLD
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEC
GRIATRTGDARWVSGEAARAWVHRLRDRVDAVLVGAGTARADDPRLTTRLPRGGRDPIRV
CEEEECCCCCEEECCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCEECCCCCCCCCEEE
VLDSDLSLPRTLALFRGGSPAPTLVAHASAAPARRYGPGVELVRCRRGKGGVDLRDLLAK
EECCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHH
LAARGVAHLLVEGGAHVHARFLEAGLVDRVAVFVAPKIAGGDGVPLVAGRGPARMADALR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECEECCCCCCEEEECCCHHHHHHHHH
LEQVAFERVGDDLLVTGVPARRAALAKNPQRG
HHHHHHHHCCCCEEEECCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TARAAPSGWRASARAPAPVAGAEAERFMRLAVREAARGLGRTSPNPAVGAVVVRDGRVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEE
GRGHHARAGGPHAEVVALRAAGALARGADVYTTLEPCDHFGKTPPCSVALLEAGVRRVFV
ECCCCCCCCCCCHHEEEEEHHHHHHCCCCEEEECHHHHHCCCCCCHHHHHHHHCCCEEEE
GSSDPNPLVNGRGMARLRRHGVAVVKGVLRDACDRLNAPWFTFITEGRPFVTLKAAVTLD
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEC
GRIATRTGDARWVSGEAARAWVHRLRDRVDAVLVGAGTARADDPRLTTRLPRGGRDPIRV
CEEEECCCCCEEECCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCEECCCCCCCCCEEE
VLDSDLSLPRTLALFRGGSPAPTLVAHASAAPARRYGPGVELVRCRRGKGGVDLRDLLAK
EECCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHH
LAARGVAHLLVEGGAHVHARFLEAGLVDRVAVFVAPKIAGGDGVPLVAGRGPARMADALR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECEECCCCCCEEEECCCHHHHHHHHH
LEQVAFERVGDDLLVTGVPARRAALAKNPQRG
HHHHHHHHCCCCEEEECCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]