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The map label for this gene is coaE [H]

Identifier: 220917969

GI number: 220917969

Start: 3171019

End: 3171654

Strand: Direct

Name: coaE [H]

Synonym: A2cp1_2870

Alternate gene names: 220917969

Gene position: 3171019-3171654 (Clockwise)

Preceding gene: 220917968

Following gene: 220917970

Centisome position: 63.05

GC content: 78.3

Gene sequence:

>636_bases
GTGCGCGTCATCGGCCTGACCGGCGGGATCGCCACCGGCAAGAGCACCTTCGCCGCGCTCCTGCGCGCGCGGGGCGCGCC
GGTGGTGGACGCGGACGCGCTGGCGCGGGCCGCGGTCGAGCCGGGGACGCCGGCGTTGGCGGAGATCGCCCGCACCTTCG
GCGCGGAGGTGCTGCGCGAGGACGGCGCGCTCGATCGGAAGGCGCTCGCCGCCCGCGTGTTCGCGGACCCGGAGGCGCGG
CGGCGGCTCGAGGCCATCACCCACCCCGCGGTCCGCCGCGCCATGCGCGAGGCGACCGATCGCCTGGCCGCGCAGGGCCA
CCCGCTCGCGTTCTACGACACGCCGCTGCTCTACGAGGTCGGGCTGGAGGCCCTGCTCGACGCGGTGGTGGTGGTGTGGG
CGCCGCGCGACGTGCAGCGCGAGCGCCTGATCCGCCGCGACCGGCTCGACGCCGCCGACGTCGACGCGCGCCTGGCCGCG
CAGCTCCCCGTGGACGAGAAGGCGGCCCGCGCGGACTTCGTGATCGACAACGCCGGCGCCCCCGAGGCGCTGGCCGGCAA
GGCCGACCGCCTGCTCGCGGACCTCCGCGCGGGCCGGGGGCGCAGGCTTCCCAACGCGCCCCCCGTGCGCTATTGA

Upstream 100 bases:

>100_bases
GAGCGTCGAGGCGCTCTCGTTCGCGGCGGGGCGGCAGAAGGCCGCGCCGGCAGCCGCCAGGCCGGCCGCGGCCGAGGCCG
CCGCGGCGCGCTGAGGGGGC

Downstream 100 bases:

>100_bases
CCGCGGCATGGGCGCGCGCGTCCACTTCGTCACGGGGTACCCGGGCTTCATCGGGAAGCGGCTGGTGCGCCGCCTCCTCG
AGGACGCGCTGCGGGCCGAC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MRVIGLTGGIATGKSTFAALLRARGAPVVDADALARAAVEPGTPALAEIARTFGAEVLREDGALDRKALAARVFADPEAR
RRLEAITHPAVRRAMREATDRLAAQGHPLAFYDTPLLYEVGLEALLDAVVVVWAPRDVQRERLIRRDRLDAADVDARLAA
QLPVDEKAARADFVIDNAGAPEALAGKADRLLADLRAGRGRRLPNAPPVRY

Sequences:

>Translated_211_residues
MRVIGLTGGIATGKSTFAALLRARGAPVVDADALARAAVEPGTPALAEIARTFGAEVLREDGALDRKALAARVFADPEAR
RRLEAITHPAVRRAMREATDRLAAQGHPLAFYDTPLLYEVGLEALLDAVVVVWAPRDVQRERLIRRDRLDAADVDARLAA
QLPVDEKAARADFVIDNAGAPEALAGKADRLLADLRAGRGRRLPNAPPVRY
>Mature_211_residues
MRVIGLTGGIATGKSTFAALLRARGAPVVDADALARAAVEPGTPALAEIARTFGAEVLREDGALDRKALAARVFADPEAR
RRLEAITHPAVRRAMREATDRLAAQGHPLAFYDTPLLYEVGLEALLDAVVVVWAPRDVQRERLIRRDRLDAADVDARLAA
QLPVDEKAARADFVIDNAGAPEALAGKADRLLADLRAGRGRRLPNAPPVRY

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=42.7777777777778, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=42.7777777777778, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI110227607, Length=206, Percent_Identity=30.5825242718447, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI110227605, Length=206, Percent_Identity=30.5825242718447, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110227603, Length=206, Percent_Identity=30.5825242718447, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110227601, Length=206, Percent_Identity=30.5825242718447, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI205277394, Length=206, Percent_Identity=30.5825242718447, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786292, Length=191, Percent_Identity=40.3141361256544, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=39.5939086294416, Blast_Score=161, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25143409, Length=194, Percent_Identity=27.8350515463918, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=214, Percent_Identity=36.4485981308411, Blast_Score=135, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24644728, Length=204, Percent_Identity=37.7450980392157, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24658602, Length=190, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22662; Mature: 22662

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIGLTGGIATGKSTFAALLRARGAPVVDADALARAAVEPGTPALAEIARTFGAEVLRE
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DGALDRKALAARVFADPEARRRLEAITHPAVRRAMREATDRLAAQGHPLAFYDTPLLYEV
CCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
GLEALLDAVVVVWAPRDVQRERLIRRDRLDAADVDARLAAQLPVDEKAARADFVIDNAGA
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCHHHHHCCCCCHHHHHHCEEEECCCC
PEALAGKADRLLADLRAGRGRRLPNAPPVRY
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVIGLTGGIATGKSTFAALLRARGAPVVDADALARAAVEPGTPALAEIARTFGAEVLRE
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DGALDRKALAARVFADPEARRRLEAITHPAVRRAMREATDRLAAQGHPLAFYDTPLLYEV
CCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
GLEALLDAVVVVWAPRDVQRERLIRRDRLDAADVDARLAAQLPVDEKAARADFVIDNAGA
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCHHHHHCCCCCHHHHHHCEEEECCCC
PEALAGKADRLLADLRAGRGRRLPNAPPVRY
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA