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The map label for this gene is purN [H]

Identifier: 220917802

GI number: 220917802

Start: 2983604

End: 2984281

Strand: Direct

Name: purN [H]

Synonym: A2cp1_2703

Alternate gene names: 220917802

Gene position: 2983604-2984281 (Clockwise)

Preceding gene: 220917801

Following gene: 220917803

Centisome position: 59.32

GC content: 77.29

Gene sequence:

>678_bases
GTGACCCGGCTCGGCGTCCTCGCCTCGGGCGGCGGCACGAACCTCCAGGCGCTGCTCGACGCCTGCGCGGCCGGGCGCGT
GGACGCGCAGGTCGCGGTGGTGCTCTCGAACGTGCCGGGCGCCGGCGCGCTGGAGCGGGCGCGCCGGGCGGGCGCGCCGG
CGGAGATCCTGCCGTCGAAGGGCGTCGCCGACCGCGCCGCCTACGACCTCACGCTGGTCGAGGCGCTCCGCGCCCACCGC
GTGGACCTGGTGTGCCTGGCCGGCTACATGCGGCTCGTCACGCCCGGCTTCCTCCGGGCCTTCGGGCCGGACGCCGCCAG
CCGCGGCTGCCCGCGGGTGATGAACATCCACCCCGGCCTGCTCCCGTCGTTCCCCGGCCTGCACGCCGCCCGGCAGGCGC
TGGAGTACGGCGCCCGCATCGCCGGCTGCACGGTCCACTTCGTGGACGAGGGCACCGACACCGGGCCGATCATCGCCCAG
GCGGTGGTCCCGGTGCTGCAGGGCGACGACGAGGCGGCCCTGTCCGCCCGCATCCAGGCCGAGGAGCACCGCCTCTACCC
GCAGGCGGTGCAGTGGTTCGCGCAGGGGCGCCTCTCGCTGGAGGGGCGCAGGGTCCGGCTCGATCGCTGCGCGCCGCACG
GCCCGTCGCCGCTGCGGAACCCGCCGCTGGAAGGATAG

Upstream 100 bases:

>100_bases
CGGCGGCGCACGCGGCGCTCCGGGCGCGCGGGCTGGAGGCGTGGACGGTCGGCGCCATCGAGGCGGGCGGGCCCGGGGAG
GCCACCTGCGAGGTGGTGCG

Downstream 100 bases:

>100_bases
ACCGGACCGCGCCCGGCCCTGGGCTCGATCGGCTAGGTCGTCCGAGTGGGAGCGTCCCTCGACCGCGGGACGAGATCGTT
TGGCGCCCGGGCGCCCTCGA

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTRLGVLASGGGTNLQALLDACAAGRVDAQVAVVLSNVPGAGALERARRAGAPAEILPSKGVADRAAYDLTLVEALRAHR
VDLVCLAGYMRLVTPGFLRAFGPDAASRGCPRVMNIHPGLLPSFPGLHAARQALEYGARIAGCTVHFVDEGTDTGPIIAQ
AVVPVLQGDDEAALSARIQAEEHRLYPQAVQWFAQGRLSLEGRRVRLDRCAPHGPSPLRNPPLEG

Sequences:

>Translated_225_residues
MTRLGVLASGGGTNLQALLDACAAGRVDAQVAVVLSNVPGAGALERARRAGAPAEILPSKGVADRAAYDLTLVEALRAHR
VDLVCLAGYMRLVTPGFLRAFGPDAASRGCPRVMNIHPGLLPSFPGLHAARQALEYGARIAGCTVHFVDEGTDTGPIIAQ
AVVPVLQGDDEAALSARIQAEEHRLYPQAVQWFAQGRLSLEGRRVRLDRCAPHGPSPLRNPPLEG
>Mature_224_residues
TRLGVLASGGGTNLQALLDACAAGRVDAQVAVVLSNVPGAGALERARRAGAPAEILPSKGVADRAAYDLTLVEALRAHRV
DLVCLAGYMRLVTPGFLRAFGPDAASRGCPRVMNIHPGLLPSFPGLHAARQALEYGARIAGCTVHFVDEGTDTGPIIAQA
VVPVLQGDDEAALSARIQAEEHRLYPQAVQWFAQGRLSLEGRRVRLDRCAPHGPSPLRNPPLEG

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=198, Percent_Identity=41.4141414141414, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI209869995, Length=198, Percent_Identity=41.4141414141414, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI209869993, Length=198, Percent_Identity=41.4141414141414, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1788846, Length=211, Percent_Identity=44.0758293838863, Blast_Score=181, Evalue=2e-47,
Organism=Escherichia coli, GI1787483, Length=163, Percent_Identity=33.7423312883436, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567511, Length=188, Percent_Identity=41.4893617021277, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320616, Length=205, Percent_Identity=28.2926829268293, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582400, Length=196, Percent_Identity=48.9795918367347, Blast_Score=182, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 23657; Mature: 23526

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLGVLASGGGTNLQALLDACAAGRVDAQVAVVLSNVPGAGALERARRAGAPAEILPSK
CCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHCCCC
GVADRAAYDLTLVEALRAHRVDLVCLAGYMRLVTPGFLRAFGPDAASRGCPRVMNIHPGL
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHCCCCHHCCCCCEEEECCCCC
LPSFPGLHAARQALEYGARIAGCTVHFVDEGTDTGPIIAQAVVPVLQGDDEAALSARIQA
CCCCCCHHHHHHHHHHCCEEECCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
EEHRLYPQAVQWFAQGRLSLEGRRVRLDRCAPHGPSPLRNPPLEG
HHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRLGVLASGGGTNLQALLDACAAGRVDAQVAVVLSNVPGAGALERARRAGAPAEILPSK
CCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHCCCC
GVADRAAYDLTLVEALRAHRVDLVCLAGYMRLVTPGFLRAFGPDAASRGCPRVMNIHPGL
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHCCCCHHCCCCCEEEECCCCC
LPSFPGLHAARQALEYGARIAGCTVHFVDEGTDTGPIIAQAVVPVLQGDDEAALSARIQA
CCCCCCHHHHHHHHHHCCEEECCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
EEHRLYPQAVQWFAQGRLSLEGRRVRLDRCAPHGPSPLRNPPLEG
HHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]