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The map label for this gene is cat1 [H]

Identifier: 220917767

GI number: 220917767

Start: 2944471

End: 2946003

Strand: Direct

Name: cat1 [H]

Synonym: A2cp1_2668

Alternate gene names: 220917767

Gene position: 2944471-2946003 (Clockwise)

Preceding gene: 220917766

Following gene: 220917768

Centisome position: 58.55

GC content: 65.82

Gene sequence:

>1533_bases
ATGTCGGATCGGATTCTCCACAAGGGCCTCAAGGCGAAGGTGATGTCCGCCGAAGAAGCCGCCGGGCTCATCCCCAACGG
CGCCATCCTCGGCATGTCGGGCTTCACCGGCGCCGGCTATCCCAAGGCCGTCCCCATCGCGCTCTCCAAGCGCGCGATCG
AGGAGCGGATGAAGGGCAAGCCCTTCAAGATCACCGCCCTCACCGGCGCGTCGACGGGCCCCGAGCTCGACCAGGCCATG
GGCCTGACGGAGTCGGTCAGCTTCCGCTTCCCGTACAACGGCGACGCGGTCATGCGGCAGAAGATCAACGAGGGCGTGAT
CGAGTACCAGGACATGCACCTGAGCCACGCCGGCTCGCTGGTGCGCTACGGGTACTACGGGCGCCCCGACAACAAGATCG
ACTTCGCCGTCATCGAGGTCACGAAGATCAAGGAGGACGGCTCGCTCGTCTTCTCGTCCTCGTGCGGCGCGAACACCGCG
TACTTCGACGTCGCGGAGAAGTACATCCTCGAGGTCAACGAGTGGCAGGACGAGCGGATGGAGGGGATGCACGACATCCT
CGGCGTGACCGGCCGTCACGGTGAGCGGACGCCGATCCCGATCCTCCGCGCCGACGACCGCGTCGGGTCGCCCACGCTGA
AGATCGACGTGTCGAAGGTCGCGGCGGTGGTGGTCACGAACAACCCCGACCGCAACGCGCCGTTCAAGGCCCCCGAGGCC
GATCACAAGCGGATCGCCCAGCACATCCTCGACTTCCTCGACGGCGAGGTGAAGGCCGGCCGGCTCCCGAAGAGCCTCAC
CCCGCTGCAGTCGGGCGTCGGGAACATCGCGAACGCGGTGCTCGTCGGCCTGAACGAGGGGCACTTCGAGAACATGATGA
GCTACACCGAGGTGATCCAGGACGGCATGCTGGACCTCCTCGACTCCGGCAAGCTCAAGATCGCGTCCGCGACGGCGTTC
TCGGTCTCGCCCGAGGGCCAGGAGCGGTTCAACAAGAACATCGACCGCTACCGCAAGCAGATCATCCTGCGCCCGCAGGA
CGTGTCGAACCACCCCGAGGTCATCCGGCGCCTCGGCTGCATCGCGATGAACGGGTTCGTCGAGGCCGACATCTACGGCC
ACGTGAACTCGACCCACATCGTGGGCAAGGGCATCGAGAACGGCATCGGCGGGTCGGGCGACTTCGCCCGCAACTCGGCG
TACACGATCTTCATGTCCCCGTCGGTCGCGAAGGGCGGGAAGATCTCGGCCATCGTCCCGTTCGCGTCGCACATCGACCA
CACGGAGCACGAGGTCAACGGCATCGTGACCGAGTACGGCTTCGCCGACCTGCGCGGGAAGAGCCCGAAGCAGAAGGCGA
AGGAAGTCATCGAGAAGTGCGCGCACCCGGACTGGCGCCCGATCCTCTGGGACTACTACAACCGCTCGCTGAAGGGCGGC
AGCTTCGGGAAGCACACGCCGCACATGCTCAAGGAGGCGTTCTCGTTCCACACGCGCTACCTCGAGACGGGCGACATGCG
CCCGAAGAAGTAG

Upstream 100 bases:

>100_bases
CTCGCGTTACTCTGCGCCACCCACAGCAGGTGTGTCGCAGCACTCTCGGTCGTACCCGCGCTTTCCGTGACAAGCAGCAG
GAACCTAGGAGGCTGAACGC

Downstream 100 bases:

>100_bases
CCGGCCTCCGAGAGACCGTCGCAGCCGCGGCGGCCGTCCTCCCGGGCGGCCGCCGTTCCATTTTCCGGCGGCGCCTCGCC
GCCGCCGCGCTAGGCTCCCG

Product: succinate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSDRILHKGLKAKVMSAEEAAGLIPNGAILGMSGFTGAGYPKAVPIALSKRAIEERMKGKPFKITALTGASTGPELDQAM
GLTESVSFRFPYNGDAVMRQKINEGVIEYQDMHLSHAGSLVRYGYYGRPDNKIDFAVIEVTKIKEDGSLVFSSSCGANTA
YFDVAEKYILEVNEWQDERMEGMHDILGVTGRHGERTPIPILRADDRVGSPTLKIDVSKVAAVVVTNNPDRNAPFKAPEA
DHKRIAQHILDFLDGEVKAGRLPKSLTPLQSGVGNIANAVLVGLNEGHFENMMSYTEVIQDGMLDLLDSGKLKIASATAF
SVSPEGQERFNKNIDRYRKQIILRPQDVSNHPEVIRRLGCIAMNGFVEADIYGHVNSTHIVGKGIENGIGGSGDFARNSA
YTIFMSPSVAKGGKISAIVPFASHIDHTEHEVNGIVTEYGFADLRGKSPKQKAKEVIEKCAHPDWRPILWDYYNRSLKGG
SFGKHTPHMLKEAFSFHTRYLETGDMRPKK

Sequences:

>Translated_510_residues
MSDRILHKGLKAKVMSAEEAAGLIPNGAILGMSGFTGAGYPKAVPIALSKRAIEERMKGKPFKITALTGASTGPELDQAM
GLTESVSFRFPYNGDAVMRQKINEGVIEYQDMHLSHAGSLVRYGYYGRPDNKIDFAVIEVTKIKEDGSLVFSSSCGANTA
YFDVAEKYILEVNEWQDERMEGMHDILGVTGRHGERTPIPILRADDRVGSPTLKIDVSKVAAVVVTNNPDRNAPFKAPEA
DHKRIAQHILDFLDGEVKAGRLPKSLTPLQSGVGNIANAVLVGLNEGHFENMMSYTEVIQDGMLDLLDSGKLKIASATAF
SVSPEGQERFNKNIDRYRKQIILRPQDVSNHPEVIRRLGCIAMNGFVEADIYGHVNSTHIVGKGIENGIGGSGDFARNSA
YTIFMSPSVAKGGKISAIVPFASHIDHTEHEVNGIVTEYGFADLRGKSPKQKAKEVIEKCAHPDWRPILWDYYNRSLKGG
SFGKHTPHMLKEAFSFHTRYLETGDMRPKK
>Mature_509_residues
SDRILHKGLKAKVMSAEEAAGLIPNGAILGMSGFTGAGYPKAVPIALSKRAIEERMKGKPFKITALTGASTGPELDQAMG
LTESVSFRFPYNGDAVMRQKINEGVIEYQDMHLSHAGSLVRYGYYGRPDNKIDFAVIEVTKIKEDGSLVFSSSCGANTAY
FDVAEKYILEVNEWQDERMEGMHDILGVTGRHGERTPIPILRADDRVGSPTLKIDVSKVAAVVVTNNPDRNAPFKAPEAD
HKRIAQHILDFLDGEVKAGRLPKSLTPLQSGVGNIANAVLVGLNEGHFENMMSYTEVIQDGMLDLLDSGKLKIASATAFS
VSPEGQERFNKNIDRYRKQIILRPQDVSNHPEVIRRLGCIAMNGFVEADIYGHVNSTHIVGKGIENGIGGSGDFARNSAY
TIFMSPSVAKGGKISAIVPFASHIDHTEHEVNGIVTEYGFADLRGKSPKQKAKEVIEKCAHPDWRPILWDYYNRSLKGGS
FGKHTPHMLKEAFSFHTRYLETGDMRPKK

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=493, Percent_Identity=43.0020283975659, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17538151, Length=494, Percent_Identity=26.1133603238866, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32563853, Length=234, Percent_Identity=31.6239316239316, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=521, Percent_Identity=43.3781190019194, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 56000; Mature: 55868

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRILHKGLKAKVMSAEEAAGLIPNGAILGMSGFTGAGYPKAVPIALSKRAIEERMKGK
CCCHHHHHCCHHHHHCHHHHCCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCC
PFKITALTGASTGPELDQAMGLTESVSFRFPYNGDAVMRQKINEGVIEYQDMHLSHAGSL
CEEEEEEECCCCCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCE
VRYGYYGRPDNKIDFAVIEVTKIKEDGSLVFSSSCGANTAYFDVAEKYILEVNEWQDERM
EECCCCCCCCCCEEEEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHH
EGMHDILGVTGRHGERTPIPILRADDRVGSPTLKIDVSKVAAVVVTNNPDRNAPFKAPEA
HHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEEHHHEEEEEEECCCCCCCCCCCCCH
DHKRIAQHILDFLDGEVKAGRLPKSLTPLQSGVGNIANAVLVGLNEGHFENMMSYTEVIQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHH
DGMLDLLDSGKLKIASATAFSVSPEGQERFNKNIDRYRKQIILRPQDVSNHPEVIRRLGC
HHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHH
IAMNGFVEADIYGHVNSTHIVGKGIENGIGGSGDFARNSAYTIFMSPSVAKGGKISAIVP
HHCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEC
FASHIDHTEHEVNGIVTEYGFADLRGKSPKQKAKEVIEKCAHPDWRPILWDYYNRSLKGG
HHHHCCCHHHHHHCEEECCCCHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
SFGKHTPHMLKEAFSFHTRYLETGDMRPKK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDRILHKGLKAKVMSAEEAAGLIPNGAILGMSGFTGAGYPKAVPIALSKRAIEERMKGK
CCHHHHHCCHHHHHCHHHHCCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCC
PFKITALTGASTGPELDQAMGLTESVSFRFPYNGDAVMRQKINEGVIEYQDMHLSHAGSL
CEEEEEEECCCCCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCE
VRYGYYGRPDNKIDFAVIEVTKIKEDGSLVFSSSCGANTAYFDVAEKYILEVNEWQDERM
EECCCCCCCCCCEEEEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHH
EGMHDILGVTGRHGERTPIPILRADDRVGSPTLKIDVSKVAAVVVTNNPDRNAPFKAPEA
HHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEEHHHEEEEEEECCCCCCCCCCCCCH
DHKRIAQHILDFLDGEVKAGRLPKSLTPLQSGVGNIANAVLVGLNEGHFENMMSYTEVIQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHH
DGMLDLLDSGKLKIASATAFSVSPEGQERFNKNIDRYRKQIILRPQDVSNHPEVIRRLGC
HHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHH
IAMNGFVEADIYGHVNSTHIVGKGIENGIGGSGDFARNSAYTIFMSPSVAKGGKISAIVP
HHCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEC
FASHIDHTEHEVNGIVTEYGFADLRGKSPKQKAKEVIEKCAHPDWRPILWDYYNRSLKGG
HHHHCCCHHHHHHCEEECCCCHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
SFGKHTPHMLKEAFSFHTRYLETGDMRPKK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]