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The map label for this gene is plsB [H]

Identifier: 220917766

GI number: 220917766

Start: 2941738

End: 2944338

Strand: Direct

Name: plsB [H]

Synonym: A2cp1_2667

Alternate gene names: 220917766

Gene position: 2941738-2944338 (Clockwise)

Preceding gene: 220917765

Following gene: 220917767

Centisome position: 58.49

GC content: 75.51

Gene sequence:

>2601_bases
GTGACGAAGGCCTCGGATCCCCAGCCGGACGGCTCGACGCCGCCGCCGTCCGCGCCTGAGGGCACCGGGCTCGGCGAGGG
CGGCGGCGTGCTGGGGCGGTGGTTCGCGCCGGTCAAGATCCCCCGCGACGCGATCGCCACGCTGCGCGCGCTCGCCGCGC
GCGGCAGCCTGGTGTTCGTGATGCGCTCGCCGGGCCTGCTCGGCTTCCTGTACCTGCGCTGGTTCCTGCGCCGCGCCGGC
CTGCCCCCGCTCCGCGCGGCGCAGGGCTTCCACGGCCTCACCGGCTGGCTCGCCCGGGTGCGGCGCACCCGCCGCGCGTT
CGAGGACGCGGTCGCCGCCGGCGAGTCGAGCCTCGTGTTCCTCGGGCGCCCGGACGCCGAGAAGAACCCGCTCGCCGCGC
TGGTGCGGCAGCAGCGGGACTTGTTCCAGCCGGTGTTCCTCGTCCCGGTGCTGCTGGTGTGGAGCCGGCGGGCGCAGCGG
CTGCAGGGCTCGATCTGGGACGTGCTGTACGGCTCGCCCGAGTCGCCGAGCGCCTTCGCGAACGCGATCGCGTTCCTGCG
CGCGTTCCGGCGGGCGGTCTTCGACGTGGGGCGCGCGCTCGACCTCAAGGAGTACCTGGCCCAGCGCGCCGCCGAGCCGG
ACGCCTCGGTGGCCCTGCGCGTGCGCGGCGCGCTCCACCAGCACCTCGCCCGCGAGTTCCGCACCGCGGTCGGCCCGCCG
CTCAAGGCGCCGTCCCGGGTGCGCGAGAAGGTGCTGCGCGATCGCTCGCTGCGCGCCGCCATCGAGGCGGTCGCCGCCGG
GACCGGCCGGCCCGCGCAGGCGGTGGTGGCCGAGGCCGAGAAGGACCTGCGCGAGATCGCGAGCAACTACGACCCGGTCT
TCGTCGGGGTGATGCGGGCGCTGCTCTCGCGGTTCTTCCGGCGGCTCTACACCAGCGTGGAGGTGGACGAGGAGGGCCTG
GCCCGGCTGCGCCGCGCGGCGGGCGAGGCGCCCTTCGTGCTGTGCCCCAGCCACAAGAGCCACGTGGACTACCTGGTCCT
CTCCTGGCTCCTCTACGAGAACGGCATGACGCCGCCGCACATCGCGGCCGGCATCAACCTCGCGTTCTGGCCGTTCGGCG
CGATCGCCCGCCGCGGCGGCGCGTTCTTCATCCGGCGCAAGGTGAAGGGCGACCGCGTCTACACCGCGGTGCTGCGCGCC
TACGTGAAGCACCTGCTGCGCGACCGCTTCCCGCAGGAGTTCTACGTGGAGGGCGGGCGCAGCCGCACCGGCAAGCTCCT
GTTCCCGAAGACCGGCCTGGTGTCGATGGAGGTGGACGCCTGGCTGGACGGCGCCGCCGACGACGTGCTGTTCGTGCCGG
TGGCGATCGACTACGAGCGGCTCATCGAGGCGTCCAGCTACGCGAACGAGCTGGCGGGCGGCGAGAAGCGCAAGGAGAGC
CTGCGCGGCCTGCTGGGCGCGGCCCGCGTGCTCCTGCGGCGGTACGAGCGGCTGTACGTCCAGTTCGAGACGCCCATCTC
GCTGCGCCAGGTGGCGGCCGAGCGGCTGGGGGCGCGCGCGGCGTCGCTGGCGGTGGACGAGGCCTGGGGCGGCGAGGCGG
AGCGGCGCGCCGCGCCCGGCGCCGCCGGGGCGGGCGACGACGCCGAGGCGAAGCGGCAGCTGGTGCAGGGGCTCGCGAAC
CGCATCGCCTACGGGATCAGCCGCGCCGTCACCATCACGCCGGTCGGGCTGGTGGCGGCGGCGCTCCTCTCGCACGTGCG
GCGCGGCCTCGGGTCCGAGGAGGTGGCGCGGCGGGTCGAGCTGCTCCGCTACGTGGCCGCCGAGGGCGGGGCCCGCTTCG
CGCGCGACCTCGCCGGCGCGCCCTCCGATCCGCGGCAGGCCGGGCCCATCGCAGACGCGGTGCGGCGCCTGGCGCGCGAC
GGGCTGGTGCGGGTGGAGGTCGCGGCGGGCGACACCATCTACCAGGTGGTCGACGAGAAGCGCCCCCTGCTCGACTACCA
CCGCAACGCGGTGATCCACCGCTACGTCGCGCCCGCGCTGGTGGCCTCGGCGGCGCGCGCCGGCGGGACGGGCGGCTCGA
CGGCGGCGGAGGTCCGCGATCGGGCGCTGTGGCTGTCCCGCCTGTTCAAGCTCGAGTTCATGTACCGGAGCGGCGCGAGC
TTCGACGAGATCTTCGAGTCGAACCTCGCGTTCCTGGTGCGGGTGCGGGCGGTGGACTGCGACGCGGGCCGGGTGCTGCC
CGGACCGGAGACCACCGCCCTCGCCTTCCTCGCCGACCTGGTCCGCGCGTACCTCGAGGCCTACCACCTCGCCGCCGCGG
CCGCCCTCGCCGCCCTCGGGTCCGACGCGCCGCGGCAGGCGCCGCTCGACCGGCGGGCGCTGGTCCGGGAGGCGCTCGAG
CGAGGCCGGGGCGAGTTCCTCTCCGGCCGGATCGCGCTCCGCGAGACGCTCTCCAAAGCCACGCTGGAGAACGCGGTGGA
GTGGCTCATGGCGCAGCGCGTGATCGCCGAGGAGGCGGGCAAGCTGCGCCTCGCCAGCCCGGCCTCGGTCGCGGAACTCC
GCGCCATCATGGACGGAATCGCTCCGCATCTGGCGATGTGA

Upstream 100 bases:

>100_bases
AAGCGCGGGTGACCGCGGACCCGCTCTCCGGCCCGCAGGCCAGGGATTTCCGGGCGGAATCCGCCCGCCAGCCGCCACCG
CTGTAATACACTCGCGCGCC

Downstream 100 bases:

>100_bases
GAAGCGTTCCGCCCCTTCCCCACGGGGCCGCGCTCGCGTTACTCTGCGCCACCCACAGCAGGTGTGTCGCAGCACTCTCG
GTCGTACCCGCGCTTTCCGT

Product: glycerol-3-phosphate O-acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 866; Mature: 865

Protein sequence:

>866_residues
MTKASDPQPDGSTPPPSAPEGTGLGEGGGVLGRWFAPVKIPRDAIATLRALAARGSLVFVMRSPGLLGFLYLRWFLRRAG
LPPLRAAQGFHGLTGWLARVRRTRRAFEDAVAAGESSLVFLGRPDAEKNPLAALVRQQRDLFQPVFLVPVLLVWSRRAQR
LQGSIWDVLYGSPESPSAFANAIAFLRAFRRAVFDVGRALDLKEYLAQRAAEPDASVALRVRGALHQHLAREFRTAVGPP
LKAPSRVREKVLRDRSLRAAIEAVAAGTGRPAQAVVAEAEKDLREIASNYDPVFVGVMRALLSRFFRRLYTSVEVDEEGL
ARLRRAAGEAPFVLCPSHKSHVDYLVLSWLLYENGMTPPHIAAGINLAFWPFGAIARRGGAFFIRRKVKGDRVYTAVLRA
YVKHLLRDRFPQEFYVEGGRSRTGKLLFPKTGLVSMEVDAWLDGAADDVLFVPVAIDYERLIEASSYANELAGGEKRKES
LRGLLGAARVLLRRYERLYVQFETPISLRQVAAERLGARAASLAVDEAWGGEAERRAAPGAAGAGDDAEAKRQLVQGLAN
RIAYGISRAVTITPVGLVAAALLSHVRRGLGSEEVARRVELLRYVAAEGGARFARDLAGAPSDPRQAGPIADAVRRLARD
GLVRVEVAAGDTIYQVVDEKRPLLDYHRNAVIHRYVAPALVASAARAGGTGGSTAAEVRDRALWLSRLFKLEFMYRSGAS
FDEIFESNLAFLVRVRAVDCDAGRVLPGPETTALAFLADLVRAYLEAYHLAAAAALAALGSDAPRQAPLDRRALVREALE
RGRGEFLSGRIALRETLSKATLENAVEWLMAQRVIAEEAGKLRLASPASVAELRAIMDGIAPHLAM

Sequences:

>Translated_866_residues
MTKASDPQPDGSTPPPSAPEGTGLGEGGGVLGRWFAPVKIPRDAIATLRALAARGSLVFVMRSPGLLGFLYLRWFLRRAG
LPPLRAAQGFHGLTGWLARVRRTRRAFEDAVAAGESSLVFLGRPDAEKNPLAALVRQQRDLFQPVFLVPVLLVWSRRAQR
LQGSIWDVLYGSPESPSAFANAIAFLRAFRRAVFDVGRALDLKEYLAQRAAEPDASVALRVRGALHQHLAREFRTAVGPP
LKAPSRVREKVLRDRSLRAAIEAVAAGTGRPAQAVVAEAEKDLREIASNYDPVFVGVMRALLSRFFRRLYTSVEVDEEGL
ARLRRAAGEAPFVLCPSHKSHVDYLVLSWLLYENGMTPPHIAAGINLAFWPFGAIARRGGAFFIRRKVKGDRVYTAVLRA
YVKHLLRDRFPQEFYVEGGRSRTGKLLFPKTGLVSMEVDAWLDGAADDVLFVPVAIDYERLIEASSYANELAGGEKRKES
LRGLLGAARVLLRRYERLYVQFETPISLRQVAAERLGARAASLAVDEAWGGEAERRAAPGAAGAGDDAEAKRQLVQGLAN
RIAYGISRAVTITPVGLVAAALLSHVRRGLGSEEVARRVELLRYVAAEGGARFARDLAGAPSDPRQAGPIADAVRRLARD
GLVRVEVAAGDTIYQVVDEKRPLLDYHRNAVIHRYVAPALVASAARAGGTGGSTAAEVRDRALWLSRLFKLEFMYRSGAS
FDEIFESNLAFLVRVRAVDCDAGRVLPGPETTALAFLADLVRAYLEAYHLAAAAALAALGSDAPRQAPLDRRALVREALE
RGRGEFLSGRIALRETLSKATLENAVEWLMAQRVIAEEAGKLRLASPASVAELRAIMDGIAPHLAM
>Mature_865_residues
TKASDPQPDGSTPPPSAPEGTGLGEGGGVLGRWFAPVKIPRDAIATLRALAARGSLVFVMRSPGLLGFLYLRWFLRRAGL
PPLRAAQGFHGLTGWLARVRRTRRAFEDAVAAGESSLVFLGRPDAEKNPLAALVRQQRDLFQPVFLVPVLLVWSRRAQRL
QGSIWDVLYGSPESPSAFANAIAFLRAFRRAVFDVGRALDLKEYLAQRAAEPDASVALRVRGALHQHLAREFRTAVGPPL
KAPSRVREKVLRDRSLRAAIEAVAAGTGRPAQAVVAEAEKDLREIASNYDPVFVGVMRALLSRFFRRLYTSVEVDEEGLA
RLRRAAGEAPFVLCPSHKSHVDYLVLSWLLYENGMTPPHIAAGINLAFWPFGAIARRGGAFFIRRKVKGDRVYTAVLRAY
VKHLLRDRFPQEFYVEGGRSRTGKLLFPKTGLVSMEVDAWLDGAADDVLFVPVAIDYERLIEASSYANELAGGEKRKESL
RGLLGAARVLLRRYERLYVQFETPISLRQVAAERLGARAASLAVDEAWGGEAERRAAPGAAGAGDDAEAKRQLVQGLANR
IAYGISRAVTITPVGLVAAALLSHVRRGLGSEEVARRVELLRYVAAEGGARFARDLAGAPSDPRQAGPIADAVRRLARDG
LVRVEVAAGDTIYQVVDEKRPLLDYHRNAVIHRYVAPALVASAARAGGTGGSTAAEVRDRALWLSRLFKLEFMYRSGASF
DEIFESNLAFLVRVRAVDCDAGRVLPGPETTALAFLADLVRAYLEAYHLAAAAALAALGSDAPRQAPLDRRALVREALER
GRGEFLSGRIALRETLSKATLENAVEWLMAQRVIAEEAGKLRLASPASVAELRAIMDGIAPHLAM

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=551, Percent_Identity=28.8566243194192, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI190358539, Length=490, Percent_Identity=26.530612244898, Blast_Score=159, Evalue=1e-38,
Organism=Escherichia coli, GI87082362, Length=476, Percent_Identity=32.3529411764706, Blast_Score=214, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71988723, Length=627, Percent_Identity=25.9968102073365, Blast_Score=166, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71988728, Length=579, Percent_Identity=26.0794473229706, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25147672, Length=510, Percent_Identity=26.078431372549, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI17864692, Length=555, Percent_Identity=26.3063063063063, Blast_Score=183, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24650754, Length=317, Percent_Identity=29.6529968454259, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21357731, Length=317, Percent_Identity=29.6529968454259, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24650752, Length=317, Percent_Identity=29.6529968454259, Blast_Score=157, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 94291; Mature: 94159

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS00265 PANCREATIC_HORMONE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKASDPQPDGSTPPPSAPEGTGLGEGGGVLGRWFAPVKIPRDAIATLRALAARGSLVFV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
MRSPGLLGFLYLRWFLRRAGLPPLRAAQGFHGLTGWLARVRRTRRAFEDAVAAGESSLVF
EECCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LGRPDAEKNPLAALVRQQRDLFQPVFLVPVLLVWSRRAQRLQGSIWDVLYGSPESPSAFA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHH
NAIAFLRAFRRAVFDVGRALDLKEYLAQRAAEPDASVALRVRGALHQHLAREFRTAVGPP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LKAPSRVREKVLRDRSLRAAIEAVAAGTGRPAQAVVAEAEKDLREIASNYDPVFVGVMRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LLSRFFRRLYTSVEVDEEGLARLRRAAGEAPFVLCPSHKSHVDYLVLSWLLYENGMTPPH
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCH
IAAGINLAFWPFGAIARRGGAFFIRRKVKGDRVYTAVLRAYVKHLLRDRFPQEFYVEGGR
HHHCCCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
SRTGKLLFPKTGLVSMEVDAWLDGAADDVLFVPVAIDYERLIEASSYANELAGGEKRKES
CCCCCEECCCCCCEEEEHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHH
LRGLLGAARVLLRRYERLYVQFETPISLRQVAAERLGARAASLAVDEAWGGEAERRAAPG
HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCC
AAGAGDDAEAKRQLVQGLANRIAYGISRAVTITPVGLVAAALLSHVRRGLGSEEVARRVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLRYVAAEGGARFARDLAGAPSDPRQAGPIADAVRRLARDGLVRVEVAAGDTIYQVVDEK
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCC
RPLLDYHRNAVIHRYVAPALVASAARAGGTGGSTAAEVRDRALWLSRLFKLEFMYRSGAS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDEIFESNLAFLVRVRAVDCDAGRVLPGPETTALAFLADLVRAYLEAYHLAAAAALAALG
HHHHHHCCHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDAPRQAPLDRRALVREALERGRGEFLSGRIALRETLSKATLENAVEWLMAQRVIAEEAG
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KLRLASPASVAELRAIMDGIAPHLAM
CEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKASDPQPDGSTPPPSAPEGTGLGEGGGVLGRWFAPVKIPRDAIATLRALAARGSLVFV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
MRSPGLLGFLYLRWFLRRAGLPPLRAAQGFHGLTGWLARVRRTRRAFEDAVAAGESSLVF
EECCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LGRPDAEKNPLAALVRQQRDLFQPVFLVPVLLVWSRRAQRLQGSIWDVLYGSPESPSAFA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHH
NAIAFLRAFRRAVFDVGRALDLKEYLAQRAAEPDASVALRVRGALHQHLAREFRTAVGPP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LKAPSRVREKVLRDRSLRAAIEAVAAGTGRPAQAVVAEAEKDLREIASNYDPVFVGVMRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LLSRFFRRLYTSVEVDEEGLARLRRAAGEAPFVLCPSHKSHVDYLVLSWLLYENGMTPPH
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCH
IAAGINLAFWPFGAIARRGGAFFIRRKVKGDRVYTAVLRAYVKHLLRDRFPQEFYVEGGR
HHHCCCCCCCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
SRTGKLLFPKTGLVSMEVDAWLDGAADDVLFVPVAIDYERLIEASSYANELAGGEKRKES
CCCCCEECCCCCCEEEEHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHH
LRGLLGAARVLLRRYERLYVQFETPISLRQVAAERLGARAASLAVDEAWGGEAERRAAPG
HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCC
AAGAGDDAEAKRQLVQGLANRIAYGISRAVTITPVGLVAAALLSHVRRGLGSEEVARRVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLRYVAAEGGARFARDLAGAPSDPRQAGPIADAVRRLARDGLVRVEVAAGDTIYQVVDEK
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCC
RPLLDYHRNAVIHRYVAPALVASAARAGGTGGSTAAEVRDRALWLSRLFKLEFMYRSGAS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
FDEIFESNLAFLVRVRAVDCDAGRVLPGPETTALAFLADLVRAYLEAYHLAAAAALAALG
HHHHHHCCHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDAPRQAPLDRRALVREALERGRGEFLSGRIALRETLSKATLENAVEWLMAQRVIAEEAG
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KLRLASPASVAELRAIMDGIAPHLAM
CEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA