Click here to switch to the map view.

The map label for this gene is metG [H]

Identifier: 220917741

GI number: 220917741

Start: 2914749

End: 2916833

Strand: Reverse

Name: metG [H]

Synonym: A2cp1_2642

Alternate gene names: 220917741

Gene position: 2916833-2914749 (Counterclockwise)

Preceding gene: 220917742

Following gene: 220917740

Centisome position: 58.0

GC content: 72.13

Gene sequence:

>2085_bases
TTGAGCCAGCGTCTCCTCGTCACGAGCGCGCTGCCGTACGCGAACGGCCCCATCCACCTCGGCCACCTGGTCGAGTACGT
CCAGACCGACGTCTACGTGCGCTTCCGGCGCGCCTGCGGAGACGACGTCGCCTACGTGTGCGCCGCCGACTCCCACGGCA
CGCCCATCGAGGTGAACGCCGCCAAGGTCGGGATGACGCCGAAGGCGTTCGTGGAGAAGTACCGCGCCGAGCAGCACGCC
GACTTCCACGCGTTCGGGGTGGAGTTCTCGACCTACTACACCACCGACTCCGACGAGAACCGCCGCTGGGCCTACCGCGT
GTACGACGCGCTCAAGGCGAAGGGGCTCATCTACAAGAAGTCGGTCGAGCAGCTCTACTGCGAGGTCGATCGGCGCTTCC
TGCCCGACCGGTTCGTGAAGGGCACCTGCCCGAAGTGCGGGACGCCCGACCAGTACGGCGACGTCTGCGAGCACTGCGGG
ACCACCTACGATCCCCGCGAGCTGAAGGACCCGTACTGCGCCATCTGCCGCTCGTCGCCGGTGGTGCGCGCCAGCGACCA
CGCGTACGTCAACCTCCGCAAGCCCGACGTGAACGCGGTCATCCACGAGTGGGTGAACGCGGAGGGGCACCTCGAGCCGG
CGGTGCGCGAGCAGGTGAAGGGCTGGCTCGCCGACCTGCAGGACTGGTGCATCACCCGCGACGCGCCGTACTTCGGCTTC
CCGGTGACCGACCCCGAGTTCCCGGGCAAGTTCCTCTACGTGTGGGTGGACGCGCCCATCGGCTACCTGTCCTCCGCCGA
GCACTACTTCGCGGCCGAGGCGCCGGACGGCGAGCGGCTGGCGCCGGCCGAGTTCGAGCGGCGCTACCTCGCGGTGGGCG
CGCCGGCCCGGCTCGAGCACTTCATCGGCAAGGACATCCTGCGCTTCCACGCGGTGTTCTGGCCGGCGATGCTCTGGGCC
ACCGGCCTGAAGCGCCCGGACCGGATGCCGGTCCACGGGCACCTCACCGTCAACGGCGAGAAGATGTCGAAGTCCCGCGG
CACCTTCGTCACCGGCCGGACCTACCTCGAGTCCGGGCTCGACCCGGAGCTGCTGCGCTACTTCTACGCGGCGAACCTGG
GCAGCGGCGTCTCCGACCTCGACCTGTCGCTGGACGAGTTCCGCAACCGCATCAACGCCGACCTCGCGAACAACGTCGCG
AACCTGGCCTCGCGCGTGGCCGCGCTGCTGCAGCGGCTGCCCGGCGGCGTCACCGCGCCGCTCGACCCCGAGATCGCCGC
CGCGACGCGCGAGGCGGTGAAGGGCGCCCGCGCCGCGTACCAGGTGCTCGAGACCCGCGACGTGGTCCGCCTGGTGAGCC
AGGCCGCCAGCGTCTGCAACCGCCGCGTGCAGGAGACGAAGCCCTGGGAGAACCCGGCCGGCGACGCGGAGCGGAGCGTG
CTCTACACCACCGGCAAGGCGCTCCTCGGCCTCGCCCGCGTGCTCGCGCCCATCCTGCCGCGCTTCTCGGCGGCGCTCGC
CGCGGCCTACGGGCGGCCCGAGCTGCCGGCCTGGACGCCGGACCTCGAGCCGTTCGACGGCGCGCCGGTGCAGGTGGTCG
AGAAGCCGCCGCAGATCGCGCGGGTGGACGCGAAGCAGGTGCAGAGGCTGATCGTGCCGGCCGCCGAGGCGGCGCCGGCG
AAGGTCGCGCGCGCCCAGAGCCCCGCCGAGACGGCCACCCGCGCCAGCGCCAAGCCGGCGCCCCCGCCGGTCCCCGGGGT
CATCCAGTACGACGACTTCGCGAAGGTGGAGCTGCGGGTCGGGCTGGTGAAGGCCGCCGAGAAGGTGGAGAAGGCCGACA
AGCTGCTGAAGCTCTCGGTGGACGTGGGCGAGCCGGAGCCGCGCACGATCGTGGCCGGCATCGCGCAGGCCTACCCGGAG
CCGCAGGCGCTGGTGGGCCGGCGCATCGTGGTGGTCGCGAACCTCGCGCCCCGTCCGCTGCGCGGGATCACCTCCCACGG
GATGCTGCTCGCCGCCGGCGAGCCGCCGAACCTCCAGGTGGTGACCGTGGGCGAGGGCATCGCGCCCGGGACACGGGTCA
AGTAG

Upstream 100 bases:

>100_bases
AGGCCGACGTCGCCATGAAGAGCGGGCAGGACGGGCGCGTGCGCCTGGAGCGGGTGCTGATCGGCCTGCTCGCCCGCGAC
AACCGGGAAAGGAGCACCCC

Downstream 100 bases:

>100_bases
CGCCTCGCACGGTCCGCCCGCCCGCCTTGCGGGCGGGGCGGACCGGGTTAGATCCGCCCGATGCTGATCGACTCGCACGC
CCACCTCGATCTCGACGACT

Product: methionyl-tRNA synthetase

Products: NA

Alternate protein names: Methionine--tRNA ligase; MetRS [H]

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MSQRLLVTSALPYANGPIHLGHLVEYVQTDVYVRFRRACGDDVAYVCAADSHGTPIEVNAAKVGMTPKAFVEKYRAEQHA
DFHAFGVEFSTYYTTDSDENRRWAYRVYDALKAKGLIYKKSVEQLYCEVDRRFLPDRFVKGTCPKCGTPDQYGDVCEHCG
TTYDPRELKDPYCAICRSSPVVRASDHAYVNLRKPDVNAVIHEWVNAEGHLEPAVREQVKGWLADLQDWCITRDAPYFGF
PVTDPEFPGKFLYVWVDAPIGYLSSAEHYFAAEAPDGERLAPAEFERRYLAVGAPARLEHFIGKDILRFHAVFWPAMLWA
TGLKRPDRMPVHGHLTVNGEKMSKSRGTFVTGRTYLESGLDPELLRYFYAANLGSGVSDLDLSLDEFRNRINADLANNVA
NLASRVAALLQRLPGGVTAPLDPEIAAATREAVKGARAAYQVLETRDVVRLVSQAASVCNRRVQETKPWENPAGDAERSV
LYTTGKALLGLARVLAPILPRFSAALAAAYGRPELPAWTPDLEPFDGAPVQVVEKPPQIARVDAKQVQRLIVPAAEAAPA
KVARAQSPAETATRASAKPAPPPVPGVIQYDDFAKVELRVGLVKAAEKVEKADKLLKLSVDVGEPEPRTIVAGIAQAYPE
PQALVGRRIVVVANLAPRPLRGITSHGMLLAAGEPPNLQVVTVGEGIAPGTRVK

Sequences:

>Translated_694_residues
MSQRLLVTSALPYANGPIHLGHLVEYVQTDVYVRFRRACGDDVAYVCAADSHGTPIEVNAAKVGMTPKAFVEKYRAEQHA
DFHAFGVEFSTYYTTDSDENRRWAYRVYDALKAKGLIYKKSVEQLYCEVDRRFLPDRFVKGTCPKCGTPDQYGDVCEHCG
TTYDPRELKDPYCAICRSSPVVRASDHAYVNLRKPDVNAVIHEWVNAEGHLEPAVREQVKGWLADLQDWCITRDAPYFGF
PVTDPEFPGKFLYVWVDAPIGYLSSAEHYFAAEAPDGERLAPAEFERRYLAVGAPARLEHFIGKDILRFHAVFWPAMLWA
TGLKRPDRMPVHGHLTVNGEKMSKSRGTFVTGRTYLESGLDPELLRYFYAANLGSGVSDLDLSLDEFRNRINADLANNVA
NLASRVAALLQRLPGGVTAPLDPEIAAATREAVKGARAAYQVLETRDVVRLVSQAASVCNRRVQETKPWENPAGDAERSV
LYTTGKALLGLARVLAPILPRFSAALAAAYGRPELPAWTPDLEPFDGAPVQVVEKPPQIARVDAKQVQRLIVPAAEAAPA
KVARAQSPAETATRASAKPAPPPVPGVIQYDDFAKVELRVGLVKAAEKVEKADKLLKLSVDVGEPEPRTIVAGIAQAYPE
PQALVGRRIVVVANLAPRPLRGITSHGMLLAAGEPPNLQVVTVGEGIAPGTRVK
>Mature_693_residues
SQRLLVTSALPYANGPIHLGHLVEYVQTDVYVRFRRACGDDVAYVCAADSHGTPIEVNAAKVGMTPKAFVEKYRAEQHAD
FHAFGVEFSTYYTTDSDENRRWAYRVYDALKAKGLIYKKSVEQLYCEVDRRFLPDRFVKGTCPKCGTPDQYGDVCEHCGT
TYDPRELKDPYCAICRSSPVVRASDHAYVNLRKPDVNAVIHEWVNAEGHLEPAVREQVKGWLADLQDWCITRDAPYFGFP
VTDPEFPGKFLYVWVDAPIGYLSSAEHYFAAEAPDGERLAPAEFERRYLAVGAPARLEHFIGKDILRFHAVFWPAMLWAT
GLKRPDRMPVHGHLTVNGEKMSKSRGTFVTGRTYLESGLDPELLRYFYAANLGSGVSDLDLSLDEFRNRINADLANNVAN
LASRVAALLQRLPGGVTAPLDPEIAAATREAVKGARAAYQVLETRDVVRLVSQAASVCNRRVQETKPWENPAGDAERSVL
YTTGKALLGLARVLAPILPRFSAALAAAYGRPELPAWTPDLEPFDGAPVQVVEKPPQIARVDAKQVQRLIVPAAEAAPAK
VARAQSPAETATRASAKPAPPPVPGVIQYDDFAKVELRVGLVKAAEKVEKADKLLKLSVDVGEPEPRTIVAGIAQAYPEP
QALVGRRIVVVANLAPRPLRGITSHGMLLAAGEPPNLQVVTVGEGIAPGTRVK

Specific function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation [H]

COG id: COG0143

COG function: function code J; Methionyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI14043022, Length=602, Percent_Identity=29.2358803986711, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI24308436, Length=544, Percent_Identity=27.2058823529412, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI4507947, Length=103, Percent_Identity=42.7184466019417, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI215490011, Length=102, Percent_Identity=34.3137254901961, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI215490009, Length=102, Percent_Identity=34.3137254901961, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI45006986, Length=102, Percent_Identity=34.3137254901961, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1788432, Length=702, Percent_Identity=40.4558404558405, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI1786861, Length=150, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540794, Length=594, Percent_Identity=27.6094276094276, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI212645096, Length=533, Percent_Identity=24.202626641651, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71992781, Length=290, Percent_Identity=27.2413793103448, Blast_Score=102, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321704, Length=429, Percent_Identity=31.9347319347319, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6321610, Length=548, Percent_Identity=22.992700729927, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24655311, Length=536, Percent_Identity=30.9701492537313, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI21358483, Length=597, Percent_Identity=25.7956448911223, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: 871 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR015413
- InterPro:   IPR004495
- InterPro:   IPR014758
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR014729
- InterPro:   IPR002547
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09334 tRNA-synt_1g; PF01588 tRNA_bind [H]

EC number: =6.1.1.10 [H]

Molecular weight: Translated: 76114; Mature: 75983

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS50886 TRBD ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRLLVTSALPYANGPIHLGHLVEYVQTDVYVRFRRACGDDVAYVCAADSHGTPIEVNA
CCCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEH
AKVGMTPKAFVEKYRAEQHADFHAFGVEFSTYYTTDSDENRRWAYRVYDALKAKGLIYKK
HHCCCCHHHHHHHHHHHHCCCEEEECEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHH
SVEQLYCEVDRRFLPDRFVKGTCPKCGTPDQYGDVCEHCGTTYDPRELKDPYCAICRSSP
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCHHHHHHCCCC
VVRASDHAYVNLRKPDVNAVIHEWVNAEGHLEPAVREQVKGWLADLQDWCITRDAPYFGF
CEEECCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PVTDPEFPGKFLYVWVDAPIGYLSSAEHYFAAEAPDGERLAPAEFERRYLAVGAPARLEH
CCCCCCCCCCEEEEEEECCCCHHCCCCCEEEECCCCCCCCCCHHHHCCEEEECCHHHHHH
FIGKDILRFHAVFWPAMLWATGLKRPDRMPVHGHLTVNGEKMSKSRGTFVTGRTYLESGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHCCCCCEEECHHHHHCCC
DPELLRYFYAANLGSGVSDLDLSLDEFRNRINADLANNVANLASRVAALLQRLPGGVTAP
CHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LDPEIAAATREAVKGARAAYQVLETRDVVRLVSQAASVCNRRVQETKPWENPAGDAERSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LYTTGKALLGLARVLAPILPRFSAALAAAYGRPELPAWTPDLEPFDGAPVQVVEKPPQIA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCHHH
RVDAKQVQRLIVPAAEAAPAKVARAQSPAETATRASAKPAPPPVPGVIQYDDFAKVELRV
HCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEECCCCEEEEEHH
GLVKAAEKVEKADKLLKLSVDVGEPEPRTIVAGIAQAYPEPQALVGRRIVVVANLAPRPL
HHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCC
RGITSHGMLLAAGEPPNLQVVTVGEGIAPGTRVK
CCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SQRLLVTSALPYANGPIHLGHLVEYVQTDVYVRFRRACGDDVAYVCAADSHGTPIEVNA
CCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEH
AKVGMTPKAFVEKYRAEQHADFHAFGVEFSTYYTTDSDENRRWAYRVYDALKAKGLIYKK
HHCCCCHHHHHHHHHHHHCCCEEEECEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHH
SVEQLYCEVDRRFLPDRFVKGTCPKCGTPDQYGDVCEHCGTTYDPRELKDPYCAICRSSP
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCHHHHHHCCCC
VVRASDHAYVNLRKPDVNAVIHEWVNAEGHLEPAVREQVKGWLADLQDWCITRDAPYFGF
CEEECCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PVTDPEFPGKFLYVWVDAPIGYLSSAEHYFAAEAPDGERLAPAEFERRYLAVGAPARLEH
CCCCCCCCCCEEEEEEECCCCHHCCCCCEEEECCCCCCCCCCHHHHCCEEEECCHHHHHH
FIGKDILRFHAVFWPAMLWATGLKRPDRMPVHGHLTVNGEKMSKSRGTFVTGRTYLESGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHCCCCCEEECHHHHHCCC
DPELLRYFYAANLGSGVSDLDLSLDEFRNRINADLANNVANLASRVAALLQRLPGGVTAP
CHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LDPEIAAATREAVKGARAAYQVLETRDVVRLVSQAASVCNRRVQETKPWENPAGDAERSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LYTTGKALLGLARVLAPILPRFSAALAAAYGRPELPAWTPDLEPFDGAPVQVVEKPPQIA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCHHH
RVDAKQVQRLIVPAAEAAPAKVARAQSPAETATRASAKPAPPPVPGVIQYDDFAKVELRV
HCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEECCCCEEEEEHH
GLVKAAEKVEKADKLLKLSVDVGEPEPRTIVAGIAQAYPEPQALVGRRIVVVANLAPRPL
HHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCC
RGITSHGMLLAAGEPPNLQVVTVGEGIAPGTRVK
CCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA