Click here to switch to the map view.

The map label for this gene is yabD [H]

Identifier: 220917740

GI number: 220917740

Start: 2913912

End: 2914688

Strand: Reverse

Name: yabD [H]

Synonym: A2cp1_2641

Alternate gene names: 220917740

Gene position: 2914688-2913912 (Counterclockwise)

Preceding gene: 220917741

Following gene: 220917737

Centisome position: 57.95

GC content: 75.8

Gene sequence:

>777_bases
ATGCTGATCGACTCGCACGCCCACCTCGATCTCGACGACTACCGGGGCGACCTCGACGCGGTCATCGCCCGCGCCCGCGA
GGCCGGCCTGGCGCGGGTGGTCTGCGTCGGCCTCTGGCGGGGGCCCGGCGACTTCGGCAACGCGCTGGCGCTCGCCGACC
GGGACCCCCGGTACTTCGCCGCGACCATCGGGATCCACCCGCACGAGGCCGCGCGCGTGCCGGAGGAGGACTGGGCCCGT
CACGAGGCGCTGGCGCGCGACCCGCGCGTCGCCGCGGTGGGCGAGACCGGCCTCGACTTCCACTACGACCACTCGCCGCG
CGACGTGCAGGAGTCCGCGTTCCGCCGGTCGCTGCGGACCGCGCGCGCCGCCGGGAAGCCGGTGGTGATCCACGTGCGCG
AGGCGGACGCCGCCTGCCTGCGCGTGCTGCGCGAGGAGGGCGTCCCCGAGGCGGGCGGGGTGATCCACTGCTTCACCGGC
GACGCCCCGGCGGCGCGCGCCTATCTCGACCTCGGCCTGTACGTCTCGGTGGCGGGCATCGTGACCTTCAAGACCGCCGA
GCCCATCCGCGAGGCGGTGCGCATCGTCCCGCGCGACCGGCTGCTGGTCGAGACCGACAGCCCGTTCCTCGCCCCGGTCC
CGTTCCGCGGCAAGCGGAACGAGCCCGCGCACGTGGTCGAGACCGCGCGCAAGGTGGCCGAGCTGTGGGGCGCGCCGCTC
GAGGAGGTGGCCGCGCGAACCGCCGAGAACACCCGGCGGCTGTTCCGGCTCGCCTGA

Upstream 100 bases:

>100_bases
CGTGGGCGAGGGCATCGCGCCCGGGACACGGGTCAAGTAGCGCCTCGCACGGTCCGCCCGCCCGCCTTGCGGGCGGGGCG
GACCGGGTTAGATCCGCCCG

Downstream 100 bases:

>100_bases
GCTGCGGCGGGCCGGCCCCGCCCCACCGTCAGCCCTCCCAGCTCCCCCACTCGTCGGCGAGGTCGGGCTCGGCGCCGGGC
CGGTTGCGCTCCTTCCAGGT

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLIDSHAHLDLDDYRGDLDAVIARAREAGLARVVCVGLWRGPGDFGNALALADRDPRYFAATIGIHPHEAARVPEEDWAR
HEALARDPRVAAVGETGLDFHYDHSPRDVQESAFRRSLRTARAAGKPVVIHVREADAACLRVLREEGVPEAGGVIHCFTG
DAPAARAYLDLGLYVSVAGIVTFKTAEPIREAVRIVPRDRLLVETDSPFLAPVPFRGKRNEPAHVVETARKVAELWGAPL
EEVAARTAENTRRLFRLA

Sequences:

>Translated_258_residues
MLIDSHAHLDLDDYRGDLDAVIARAREAGLARVVCVGLWRGPGDFGNALALADRDPRYFAATIGIHPHEAARVPEEDWAR
HEALARDPRVAAVGETGLDFHYDHSPRDVQESAFRRSLRTARAAGKPVVIHVREADAACLRVLREEGVPEAGGVIHCFTG
DAPAARAYLDLGLYVSVAGIVTFKTAEPIREAVRIVPRDRLLVETDSPFLAPVPFRGKRNEPAHVVETARKVAELWGAPL
EEVAARTAENTRRLFRLA
>Mature_258_residues
MLIDSHAHLDLDDYRGDLDAVIARAREAGLARVVCVGLWRGPGDFGNALALADRDPRYFAATIGIHPHEAARVPEEDWAR
HEALARDPRVAAVGETGLDFHYDHSPRDVQESAFRRSLRTARAAGKPVVIHVREADAACLRVLREEGVPEAGGVIHCFTG
DAPAARAYLDLGLYVSVAGIVTFKTAEPIREAVRIVPRDRLLVETDSPFLAPVPFRGKRNEPAHVVETARKVAELWGAPL
EEVAARTAENTRRLFRLA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=268, Percent_Identity=30.5970149253731, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI14042943, Length=277, Percent_Identity=28.158844765343, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI225903439, Length=241, Percent_Identity=27.3858921161826, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI110349734, Length=274, Percent_Identity=27.7372262773723, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI110349730, Length=274, Percent_Identity=27.7372262773723, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061853, Length=279, Percent_Identity=27.2401433691756, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=27.2373540856031, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=26.4957264957265, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787342, Length=263, Percent_Identity=44.106463878327, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI48994985, Length=267, Percent_Identity=32.2097378277154, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=29.8449612403101, Blast_Score=114, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=30.1418439716312, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17543026, Length=220, Percent_Identity=33.1818181818182, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17565396, Length=221, Percent_Identity=33.4841628959276, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=27.4074074074074, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=32.2916666666667, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221330018, Length=275, Percent_Identity=30.5454545454545, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24586117, Length=275, Percent_Identity=30.5454545454545, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28322; Mature: 28322

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSHAHLDLDDYRGDLDAVIARAREAGLARVVCVGLWRGPGDFGNALALADRDPRYFA
CEECCCCCCCHHHHCCCHHHHHHHHHHCCHHEEEEEEEECCCCCCCCEEEECCCCCCEEE
ATIGIHPHEAARVPEEDWARHEALARDPRVAAVGETGLDFHYDHSPRDVQESAFRRSLRT
EEECCCCHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
ARAAGKPVVIHVREADAACLRVLREEGVPEAGGVIHCFTGDAPAARAYLDLGLYVSVAGI
HHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHEEEEHH
VTFKTAEPIREAVRIVPRDRLLVETDSPFLAPVPFRGKRNEPAHVVETARKVAELWGAPL
EEECCHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCH
EEVAARTAENTRRLFRLA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIDSHAHLDLDDYRGDLDAVIARAREAGLARVVCVGLWRGPGDFGNALALADRDPRYFA
CEECCCCCCCHHHHCCCHHHHHHHHHHCCHHEEEEEEEECCCCCCCCEEEECCCCCCEEE
ATIGIHPHEAARVPEEDWARHEALARDPRVAAVGETGLDFHYDHSPRDVQESAFRRSLRT
EEECCCCHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
ARAAGKPVVIHVREADAACLRVLREEGVPEAGGVIHCFTGDAPAARAYLDLGLYVSVAGI
HHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHEEEEHH
VTFKTAEPIREAVRIVPRDRLLVETDSPFLAPVPFRGKRNEPAHVVETARKVAELWGAPL
EEECCHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCH
EEVAARTAENTRRLFRLA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]