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The map label for this gene is norB [H]

Identifier: 220917649

GI number: 220917649

Start: 2825767

End: 2828055

Strand: Reverse

Name: norB [H]

Synonym: A2cp1_2550

Alternate gene names: 220917649

Gene position: 2828055-2825767 (Counterclockwise)

Preceding gene: 220917650

Following gene: 220917648

Centisome position: 56.23

GC content: 71.17

Gene sequence:

>2289_bases
ATGAGCCCGAAGGCCCGCGCAGTCTCGCTGTTCGTCATCGTCGCCTGCTTCACCGTCCTCATCTTCGGCGGCGCCCAGAT
CTCGAAGCACAAGCCGCCCATCCCCGCCCGCGCGGTCGCGCCGTCCGGCGAGGTGATCTTCACCGCCGAGGACGTGGCCC
TCGGCCAGCGCCAGTACCTGTCCCGCGGCGGCCAGCAGACCGGCTCGGTGTGGGGCCACGGCGCGTACCTCGCGCCGGAC
TGGTCGGCCGACGCGCTCCACCGGACCGGCCTCGTCACCGCCGGCCTGAAGCGCGGCCTCACCCCGGGCGCGGCCGCCGG
CTTCACGCAGGCGGACCTCGCCGCGCTGCCCGCCGGTGAGCGCGGCCGCGTCCAGGCCGAGGTGGCCGAGGAGCTGCGGC
AGAACCGCTACGACCCCGCCAGCGACACGCTGACGCTGTCGCCCGGCCAGGTCGCGGCGTACCCGGCGCTGGTGGCGTAC
TACACGCGGCTGTTCCGCGACGGCAACGACCCCATGTCGATCCCGGCCGGCTTCGTGCCGGACGCGGCCGACGCGAAGGC
CATCACCGCGTTCTTCTTCTGGACCGCCTGGGCCGCCGGCACCAACCGGCCCGGCGAGACGTTCACGTACACCGCGAACT
TCCCGTTCGACCCGCTGGTCGGCAACGGCCCGCTGCCCTCGTCGCTGGTCTGGTCGATCGTCTCGATGGTGCTGCTCATC
CTCGGCACCGCGCTCGCGATCTTCTACTACCTGCGCCTGCGCGCGAAGGACCCCGAGCACCACGTCAAGATCGCGCCGCT
GCAGGAGCCGAAGCCCACGCCCAGCCAGCGCGCCGCGCTGCCGTACTTCGCGGTCGCCATCGTCCTCTTCATCCTGCAGG
CCGCGCTCGGCTCGCTGACCGGCCACTTCGCCGTCGAGGGCAACAAGCTGTTCGGCATCGACCTCGGCATGCTGCTGCCG
TACGCCGCCACCCGCGGCTGGCACCTGCAGCTCGCCGTGTTCTGGATCGCGACCTGCTGGCTCGCCACCGGCCTGTTCAT
CGGCCCGGCGGTCGCGGGCGGCCACGAGCCGAAGGGCCAGAAGGCGCTGGTCTGGACGCTTCTCGGCGCGCTGGTGGTGG
TCGTGGTCGGCGCGCTCGCCGGCACCTACCTCGGCGTCCGCGGCAAGCTCTCCGGCCCGAACGGCTGGCTCGTCGGCAAC
CAGGGCTACGAGTACATCGAGCTGGGCCGCGTGTGGCAGGTGGCGCTCATCGCCGGCATGCTGCTGTGGCTGTTCCTGGT
GTACCGCGCCATCAAGCCGGCGCTGAAGGCCGAGCAGGACCGCGGCGGCCTCACGCACCTGCTGCTCTACGCCTCGGTCT
CCATCCCGCTGTTCTACTCGGTGGGCCTGTTCTACACGCCGGGCACGCACATCGCCGTCGCCGACTACTGGCGCTGGTGG
GTGGTGCACCTGTGGGTCGAGAACTTCTTCGAGGTGTTCGCGACCGTCGCGCTCGCCTTCATCCTCTCGAAGATCGGCGC
GGTGGGCGAGCGGTCCGCGACGCGCGCCACCCACTTCTCCATCCTGCTGTACCTGGGCGCCGGCATCATCGGCACGTTCC
ACCACCTGTACTTCACCGGCTCGCCGCTGTTCATCACCGCGCTCGGCGCCACGTTCTCCGCGCTGGAGATCGTCCCGCTC
ACGCTGCTCGGGTTCGAGGTGTACGAGAACCTGAAGCTGGCCCGCAGCGGCGGGAACGCCACGCCGTGGAAGTGGCCGCT
CTACTTCTTCGTGGCGGTGGCGTTCTGGAACGCGGTGGGCGCGGGCGTGCTGGGCTTCCTCATCAACCCGCCCATCGTGC
TGTACTACGCGCAGGGCCTGAACACGACGCCCATCCACTCGCACGGCGCGCTGTTCGGCGTGTACGGCTTCCTCGCCATC
GCGCTGATGCTGTTCTCGATGCGCAACATCGTGCGGACCGCGGCCTGGAGCGACCGGCTCCTCAAGATCGCGTTCTGGGG
CCTCAACGCGGGCCTGGCGGGCATGATCGTCCTCTCGCTCCTGCCCGCCGGCATCTACCAGCTCGTCATCGCGGTGCGCG
AGGGCCTCTGGTACGCGCGCAGCCCCGAGGTCACCGGCAGCGCCTTCATCCACGCGGTCACCTGGGCCCGCGTGCTGCCC
GACCTGGTGTTCGTCGGCGGCGCGCTCGCGCTCCTCGGCTTCGTGCTCCGGGCCATCGTGCTCGACGTGAAGCTGCGCCG
CGCCGATCCCGCGGACGGCGAGGCGGCGACCGTGCGCAAGGCGGCCTAG

Upstream 100 bases:

>100_bases
CGTCACGCCGGCTCCATCCACCCCGGCGCCCAGCCGTCCACCGCGCACCGCTTCGGCTGCGCCGGCTAACCCACTTCACG
CACCAGGAGAGACGTCCGAC

Downstream 100 bases:

>100_bases
ACCGCACGCGGCGCGAGCCGCCGAGTGCTCCTCCCCGGCCGGCCGGGGGTGGGACCGGGTTCCTCCGGCCCGCCCCCGGC
CGTTCCCGTCTGCGGTGACC

Product: Nitric-oxide reductase

Products: NA

Alternate protein names: NOR large subunit; Nitric oxide reductase cytochrome b subunit [H]

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MSPKARAVSLFVIVACFTVLIFGGAQISKHKPPIPARAVAPSGEVIFTAEDVALGQRQYLSRGGQQTGSVWGHGAYLAPD
WSADALHRTGLVTAGLKRGLTPGAAAGFTQADLAALPAGERGRVQAEVAEELRQNRYDPASDTLTLSPGQVAAYPALVAY
YTRLFRDGNDPMSIPAGFVPDAADAKAITAFFFWTAWAAGTNRPGETFTYTANFPFDPLVGNGPLPSSLVWSIVSMVLLI
LGTALAIFYYLRLRAKDPEHHVKIAPLQEPKPTPSQRAALPYFAVAIVLFILQAALGSLTGHFAVEGNKLFGIDLGMLLP
YAATRGWHLQLAVFWIATCWLATGLFIGPAVAGGHEPKGQKALVWTLLGALVVVVVGALAGTYLGVRGKLSGPNGWLVGN
QGYEYIELGRVWQVALIAGMLLWLFLVYRAIKPALKAEQDRGGLTHLLLYASVSIPLFYSVGLFYTPGTHIAVADYWRWW
VVHLWVENFFEVFATVALAFILSKIGAVGERSATRATHFSILLYLGAGIIGTFHHLYFTGSPLFITALGATFSALEIVPL
TLLGFEVYENLKLARSGGNATPWKWPLYFFVAVAFWNAVGAGVLGFLINPPIVLYYAQGLNTTPIHSHGALFGVYGFLAI
ALMLFSMRNIVRTAAWSDRLLKIAFWGLNAGLAGMIVLSLLPAGIYQLVIAVREGLWYARSPEVTGSAFIHAVTWARVLP
DLVFVGGALALLGFVLRAIVLDVKLRRADPADGEAATVRKAA

Sequences:

>Translated_762_residues
MSPKARAVSLFVIVACFTVLIFGGAQISKHKPPIPARAVAPSGEVIFTAEDVALGQRQYLSRGGQQTGSVWGHGAYLAPD
WSADALHRTGLVTAGLKRGLTPGAAAGFTQADLAALPAGERGRVQAEVAEELRQNRYDPASDTLTLSPGQVAAYPALVAY
YTRLFRDGNDPMSIPAGFVPDAADAKAITAFFFWTAWAAGTNRPGETFTYTANFPFDPLVGNGPLPSSLVWSIVSMVLLI
LGTALAIFYYLRLRAKDPEHHVKIAPLQEPKPTPSQRAALPYFAVAIVLFILQAALGSLTGHFAVEGNKLFGIDLGMLLP
YAATRGWHLQLAVFWIATCWLATGLFIGPAVAGGHEPKGQKALVWTLLGALVVVVVGALAGTYLGVRGKLSGPNGWLVGN
QGYEYIELGRVWQVALIAGMLLWLFLVYRAIKPALKAEQDRGGLTHLLLYASVSIPLFYSVGLFYTPGTHIAVADYWRWW
VVHLWVENFFEVFATVALAFILSKIGAVGERSATRATHFSILLYLGAGIIGTFHHLYFTGSPLFITALGATFSALEIVPL
TLLGFEVYENLKLARSGGNATPWKWPLYFFVAVAFWNAVGAGVLGFLINPPIVLYYAQGLNTTPIHSHGALFGVYGFLAI
ALMLFSMRNIVRTAAWSDRLLKIAFWGLNAGLAGMIVLSLLPAGIYQLVIAVREGLWYARSPEVTGSAFIHAVTWARVLP
DLVFVGGALALLGFVLRAIVLDVKLRRADPADGEAATVRKAA
>Mature_761_residues
SPKARAVSLFVIVACFTVLIFGGAQISKHKPPIPARAVAPSGEVIFTAEDVALGQRQYLSRGGQQTGSVWGHGAYLAPDW
SADALHRTGLVTAGLKRGLTPGAAAGFTQADLAALPAGERGRVQAEVAEELRQNRYDPASDTLTLSPGQVAAYPALVAYY
TRLFRDGNDPMSIPAGFVPDAADAKAITAFFFWTAWAAGTNRPGETFTYTANFPFDPLVGNGPLPSSLVWSIVSMVLLIL
GTALAIFYYLRLRAKDPEHHVKIAPLQEPKPTPSQRAALPYFAVAIVLFILQAALGSLTGHFAVEGNKLFGIDLGMLLPY
AATRGWHLQLAVFWIATCWLATGLFIGPAVAGGHEPKGQKALVWTLLGALVVVVVGALAGTYLGVRGKLSGPNGWLVGNQ
GYEYIELGRVWQVALIAGMLLWLFLVYRAIKPALKAEQDRGGLTHLLLYASVSIPLFYSVGLFYTPGTHIAVADYWRWWV
VHLWVENFFEVFATVALAFILSKIGAVGERSATRATHFSILLYLGAGIIGTFHHLYFTGSPLFITALGATFSALEIVPLT
LLGFEVYENLKLARSGGNATPWKWPLYFFVAVAFWNAVGAGVLGFLINPPIVLYYAQGLNTTPIHSHGALFGVYGFLAIA
LMLFSMRNIVRTAAWSDRLLKIAFWGLNAGLAGMIVLSLLPAGIYQLVIAVREGLWYARSPEVTGSAFIHAVTWARVLPD
LVFVGGALALLGFVLRAIVLDVKLRRADPADGEAATVRKAA

Specific function: Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen red

COG id: COG3256

COG function: function code P; Nitric oxide reductase large subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.7.99.7 [H]

Molecular weight: Translated: 82060; Mature: 81928

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPKARAVSLFVIVACFTVLIFGGAQISKHKPPIPARAVAPSGEVIFTAEDVALGQRQYL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
SRGGQQTGSVWGHGAYLAPDWSADALHRTGLVTAGLKRGLTPGAAAGFTQADLAALPAGE
HCCCCCCCCCCCCCCEECCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCC
RGRVQAEVAEELRQNRYDPASDTLTLSPGQVAAYPALVAYYTRLFRDGNDPMSIPAGFVP
CCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DAADAKAITAFFFWTAWAAGTNRPGETFTYTANFPFDPLVGNGPLPSSLVWSIVSMVLLI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
LGTALAIFYYLRLRAKDPEHHVKIAPLQEPKPTPSQRAALPYFAVAIVLFILQAALGSLT
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GHFAVEGNKLFGIDLGMLLPYAATRGWHLQLAVFWIATCWLATGLFIGPAVAGGHEPKGQ
CCEEEECCEEEEEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KALVWTLLGALVVVVVGALAGTYLGVRGKLSGPNGWLVGNQGYEYIELGRVWQVALIAGM
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
LLWLFLVYRAIKPALKAEQDRGGLTHLLLYASVSIPLFYSVGLFYTPGTHIAVADYWRWW
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHEECCEEECCCCCEEHHHHHHHH
VVHLWVENFFEVFATVALAFILSKIGAVGERSATRATHFSILLYLGAGIIGTFHHLYFTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPLFITALGATFSALEIVPLTLLGFEVYENLKLARSGGNATPWKWPLYFFVAVAFWNAVG
CCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AGVLGFLINPPIVLYYAQGLNTTPIHSHGALFGVYGFLAIALMLFSMRNIVRTAAWSDRL
HHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
LKIAFWGLNAGLAGMIVLSLLPAGIYQLVIAVREGLWYARSPEVTGSAFIHAVTWARVLP
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
DLVFVGGALALLGFVLRAIVLDVKLRRADPADGEAATVRKAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPKARAVSLFVIVACFTVLIFGGAQISKHKPPIPARAVAPSGEVIFTAEDVALGQRQYL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
SRGGQQTGSVWGHGAYLAPDWSADALHRTGLVTAGLKRGLTPGAAAGFTQADLAALPAGE
HCCCCCCCCCCCCCCEECCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCC
RGRVQAEVAEELRQNRYDPASDTLTLSPGQVAAYPALVAYYTRLFRDGNDPMSIPAGFVP
CCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DAADAKAITAFFFWTAWAAGTNRPGETFTYTANFPFDPLVGNGPLPSSLVWSIVSMVLLI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
LGTALAIFYYLRLRAKDPEHHVKIAPLQEPKPTPSQRAALPYFAVAIVLFILQAALGSLT
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
GHFAVEGNKLFGIDLGMLLPYAATRGWHLQLAVFWIATCWLATGLFIGPAVAGGHEPKGQ
CCEEEECCEEEEEEHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KALVWTLLGALVVVVVGALAGTYLGVRGKLSGPNGWLVGNQGYEYIELGRVWQVALIAGM
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
LLWLFLVYRAIKPALKAEQDRGGLTHLLLYASVSIPLFYSVGLFYTPGTHIAVADYWRWW
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHEECCEEECCCCCEEHHHHHHHH
VVHLWVENFFEVFATVALAFILSKIGAVGERSATRATHFSILLYLGAGIIGTFHHLYFTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPLFITALGATFSALEIVPLTLLGFEVYENLKLARSGGNATPWKWPLYFFVAVAFWNAVG
CCCEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AGVLGFLINPPIVLYYAQGLNTTPIHSHGALFGVYGFLAIALMLFSMRNIVRTAAWSDRL
HHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
LKIAFWGLNAGLAGMIVLSLLPAGIYQLVIAVREGLWYARSPEVTGSAFIHAVTWARVLP
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
DLVFVGGALALLGFVLRAIVLDVKLRRADPADGEAATVRKAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7508388; 2542222; 9521721 [H]