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The map label for this gene is otsA [H]

Identifier: 220917606

GI number: 220917606

Start: 2766736

End: 2769009

Strand: Reverse

Name: otsA [H]

Synonym: A2cp1_2506

Alternate gene names: 220917606

Gene position: 2769009-2766736 (Counterclockwise)

Preceding gene: 220917607

Following gene: 220917603

Centisome position: 55.06

GC content: 74.8

Gene sequence:

>2274_bases
ATGCGCGCGGTCCTGAAGGTCCTCGTCCCGCTGATGCTCCTCCTGGGCGCCATCGCCTGGGGGGCGTCGGTCCTCGTCGA
GCACACGGCCCGGCGCTGGTTCGATCGTGACACCCGCATGCGGGCCGAGCTGGCGGTCTCCGGCGCCCGCGACGGGCTCG
AGCGCGCGCTCCGCAAGGGCGAGCGCGCGCGGGTGCGCCGTATCCTGGGCGAGGTGGCGCGCGACGAGCGGGTGCTCGGC
GCGGCGGCCTGCGATCCGGAGGGGGCGCTGGTCGCGAGCACGTCCGAGTACCCGGAGCCGTTCGACTGCGGGCGGATCCG
GGCGCACGCGGCGGCGGGCGCGGCCGCGCCCGTCACCTCGGCGTTCGAGGCGCCGTACGGGGAGACGCGGGTGCACCTCA
CCGCGGTGCCGCTGGCGGACGAGGAGGGGCCGCTCGGGTTCGTGGCGCTCGTGCACGACATGAGCTGGGTCGCGACGCGC
GAGGAGCAGACGCGCGGCTTCCTGGCGGTCGCGTTCGCGATCGTGGCGCTCGCCGCGGCGGTGGCGACGACGCTCGCGGC
GCGCTTCTCGTGGCGCGGGTGGAGCGCGGAGCTGCAGCGGGTGCTCCGGGCCACCTGGCTGATGCCGGGCCCCTCGGCCC
CGCCGCGCACCCGGCGCGAGTTCCAGCCGCTCCTGTCCGACGTGCGCGCCCTGGTGTCGGAGCTCGCGTCGGAGCAGTCG
GAGGGCAGGGCGGGGCTCTGGTCGCCGGCCCGCCTGCGCGACGCGCTCGCCCGGCACCTCCCCGGCAGCGAGGTGATCGT
GGTCGCGAACCGCGAGCCCTACATCCACGAGCGACGCGACGGCGTGCTCCGGGTGCAGCACCCGGCCAGCGGCCTCGTCA
CCGCGCTCGAGCCCGTGGTCCAAGCCACCGGCGGGACCTGGATCGCGCACGGCAGCGGCGCCGCCGATCGCGAGGTGGTG
GACCGGCACGCCCGCGTGCGCGTACCGCCCGACGACCCCGCCTACACGCTGCGGCGCGTGTGGCTGACCGCAGCCGAGGA
GGAGGGCTACTACTACGGCTTCTCGAACGAGGGGCTGTGGCCGCTGTGCCACGTGGCGCACACCCGGCCCACCTTCCGCG
GCGGGGACTTCGCCGCGTACCGCGACGCGAACCGCAAGTTCGCCGACGCGGTGTGCGAGGAGGCGAACGGCCCGGACCCG
GTGGTGCTGGTGCAGGACTACCACTTCGCGCTGCTGCCCCGGATGATCCGCGAGCGGCTGCCGCGCGCGACCATCATCAC
GTTCTGGCACATCCCCTGGCCCAACTCCGAGCGCTTCGGGATCTGCCCGTGGGGCCCGGAGATCCTGGAGGGCATGCTCG
GCTCGAGCATCCTCGGGTTCCACGTCCAGGCGCACTGCAACAACTTCCTCGACTCGGTGGACCGCTACCTCGAGGCGCGG
CTCGACCGCGAGCGCCAGAGCGTGGTGCTGGGCGGCCAGGAGACGCTGATCCGCGCGTACCCGATCTCCATCGACTGGCC
CACCCGCTGGGCGGCGGACGCGCCGGCGGCGCCCCTCTGCCGCGAGCGCGTGTTCGCGGACCTCGGCCTCGCGCCCGACG
CGCTGCTGGGCGTCGGCATCGACCGGCTCGACTACACCAAGGGGATCGAGGAGCGGCTGCTGGCGGTGGAGCGGCTGCTG
GAGCGCTTCCCGCAGTTCCGCGGCCGGTTCACGTTCGCTCAGCTCGCCGCCCCCAGCCGCACGCGCATCCCGCGCTACCA
GGAGCTGAACCGCAACGTCGAGGAGGTCGCGCGCCGGGTGAACGAGCGGTTCGGCGAGGGCGACTACCGGCCCATCGTGC
TGCTCCGCGAGCACCACGAGCCGCCCACCGTGTTCCGCTACTACCGCGCCGCGGACCTCTGCTACGTGTCGTCGCTGCAC
GACGGCATGAACCTGGTGGCGAAGGAGTTCGTGGCGGCCCGCGACGACGAGGCGGGCGTGCTGGTGCTGTCGCGGTTCAC
CGGCGCCTCGCGCGAGCTGGGCGAGGCGCTGCTGGTGAACCCGTACGACCTCGAGGAGGCCAGCTCGGCCCTGGCGGCGG
CGCTGGCCATGCCGCGCGAGGAGCAGCGGGAGCGGATGCGGGCGCTGCGGACGTTCGTGTCCGAGTTCAACGTGTACCGC
TGGGCGGGGCGCATGCTGGTGGACGCGGGGCGGCTGCGCAAGCGGGACCGGGTCTCCGGGCGCATCACCGTGCCGTTCCG
GACCGTGCCCGGCGAGGCCGGCGGCCGGCGCTGA

Upstream 100 bases:

>100_bases
CCGGGCGGGCATCGGAGGGACCCCACGACCGTGCGTCCTCCTGGCGCAGGGTCCCCCGCAGGCGGTTGGAGGGCCAACCG
ACCGGACATAGGATGCTCCG

Downstream 100 bases:

>100_bases
CGCGGGGCCGCTGCGTCAGTCGCAGTCGTCGCCGCCCTCCGGGCAGCGCCCGGAGCGGTGCGGCGCCGGGCTGCTCAGGC
CCAGCGCGGCGTTGACCAGC

Product: Alpha,alpha-trehalose-phosphate synthase

Products: UDP; alpha,alpha'-Trehalose 6-phosphate

Alternate protein names: TPS; Trehalose-6-phosphate synthase [H]

Number of amino acids: Translated: 757; Mature: 757

Protein sequence:

>757_residues
MRAVLKVLVPLMLLLGAIAWGASVLVEHTARRWFDRDTRMRAELAVSGARDGLERALRKGERARVRRILGEVARDERVLG
AAACDPEGALVASTSEYPEPFDCGRIRAHAAAGAAAPVTSAFEAPYGETRVHLTAVPLADEEGPLGFVALVHDMSWVATR
EEQTRGFLAVAFAIVALAAAVATTLAARFSWRGWSAELQRVLRATWLMPGPSAPPRTRREFQPLLSDVRALVSELASEQS
EGRAGLWSPARLRDALARHLPGSEVIVVANREPYIHERRDGVLRVQHPASGLVTALEPVVQATGGTWIAHGSGAADREVV
DRHARVRVPPDDPAYTLRRVWLTAAEEEGYYYGFSNEGLWPLCHVAHTRPTFRGGDFAAYRDANRKFADAVCEEANGPDP
VVLVQDYHFALLPRMIRERLPRATIITFWHIPWPNSERFGICPWGPEILEGMLGSSILGFHVQAHCNNFLDSVDRYLEAR
LDRERQSVVLGGQETLIRAYPISIDWPTRWAADAPAAPLCRERVFADLGLAPDALLGVGIDRLDYTKGIEERLLAVERLL
ERFPQFRGRFTFAQLAAPSRTRIPRYQELNRNVEEVARRVNERFGEGDYRPIVLLREHHEPPTVFRYYRAADLCYVSSLH
DGMNLVAKEFVAARDDEAGVLVLSRFTGASRELGEALLVNPYDLEEASSALAAALAMPREEQRERMRALRTFVSEFNVYR
WAGRMLVDAGRLRKRDRVSGRITVPFRTVPGEAGGRR

Sequences:

>Translated_757_residues
MRAVLKVLVPLMLLLGAIAWGASVLVEHTARRWFDRDTRMRAELAVSGARDGLERALRKGERARVRRILGEVARDERVLG
AAACDPEGALVASTSEYPEPFDCGRIRAHAAAGAAAPVTSAFEAPYGETRVHLTAVPLADEEGPLGFVALVHDMSWVATR
EEQTRGFLAVAFAIVALAAAVATTLAARFSWRGWSAELQRVLRATWLMPGPSAPPRTRREFQPLLSDVRALVSELASEQS
EGRAGLWSPARLRDALARHLPGSEVIVVANREPYIHERRDGVLRVQHPASGLVTALEPVVQATGGTWIAHGSGAADREVV
DRHARVRVPPDDPAYTLRRVWLTAAEEEGYYYGFSNEGLWPLCHVAHTRPTFRGGDFAAYRDANRKFADAVCEEANGPDP
VVLVQDYHFALLPRMIRERLPRATIITFWHIPWPNSERFGICPWGPEILEGMLGSSILGFHVQAHCNNFLDSVDRYLEAR
LDRERQSVVLGGQETLIRAYPISIDWPTRWAADAPAAPLCRERVFADLGLAPDALLGVGIDRLDYTKGIEERLLAVERLL
ERFPQFRGRFTFAQLAAPSRTRIPRYQELNRNVEEVARRVNERFGEGDYRPIVLLREHHEPPTVFRYYRAADLCYVSSLH
DGMNLVAKEFVAARDDEAGVLVLSRFTGASRELGEALLVNPYDLEEASSALAAALAMPREEQRERMRALRTFVSEFNVYR
WAGRMLVDAGRLRKRDRVSGRITVPFRTVPGEAGGRR
>Mature_757_residues
MRAVLKVLVPLMLLLGAIAWGASVLVEHTARRWFDRDTRMRAELAVSGARDGLERALRKGERARVRRILGEVARDERVLG
AAACDPEGALVASTSEYPEPFDCGRIRAHAAAGAAAPVTSAFEAPYGETRVHLTAVPLADEEGPLGFVALVHDMSWVATR
EEQTRGFLAVAFAIVALAAAVATTLAARFSWRGWSAELQRVLRATWLMPGPSAPPRTRREFQPLLSDVRALVSELASEQS
EGRAGLWSPARLRDALARHLPGSEVIVVANREPYIHERRDGVLRVQHPASGLVTALEPVVQATGGTWIAHGSGAADREVV
DRHARVRVPPDDPAYTLRRVWLTAAEEEGYYYGFSNEGLWPLCHVAHTRPTFRGGDFAAYRDANRKFADAVCEEANGPDP
VVLVQDYHFALLPRMIRERLPRATIITFWHIPWPNSERFGICPWGPEILEGMLGSSILGFHVQAHCNNFLDSVDRYLEAR
LDRERQSVVLGGQETLIRAYPISIDWPTRWAADAPAAPLCRERVFADLGLAPDALLGVGIDRLDYTKGIEERLLAVERLL
ERFPQFRGRFTFAQLAAPSRTRIPRYQELNRNVEEVARRVNERFGEGDYRPIVLLREHHEPPTVFRYYRAADLCYVSSLH
DGMNLVAKEFVAARDDEAGVLVLSRFTGASRELGEALLVNPYDLEEASSALAAALAMPREEQRERMRALRTFVSEFNVYR
WAGRMLVDAGRLRKRDRVSGRITVPFRTVPGEAGGRR

Specific function: Catalyzes the transfer of glucose from a nucleoside diphosphate-glucose to glucose-6-phosphate to form trehalose-6- phosphate and nucleoside diphosphate [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=468, Percent_Identity=31.1965811965812, Blast_Score=198, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71987012, Length=429, Percent_Identity=26.8065268065268, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI115533558, Length=367, Percent_Identity=26.7029972752044, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533560, Length=367, Percent_Identity=26.7029972752044, Blast_Score=106, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319602, Length=482, Percent_Identity=31.3278008298755, Blast_Score=240, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6323537, Length=394, Percent_Identity=28.4263959390863, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323917, Length=389, Percent_Identity=27.5064267352185, Blast_Score=150, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320279, Length=387, Percent_Identity=26.6149870801034, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19920676, Length=499, Percent_Identity=35.6713426853707, Blast_Score=264, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: 2.4.1.15

Molecular weight: Translated: 84489; Mature: 84489

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLKVLVPLMLLLGAIAWGASVLVEHTARRWFDRDTRMRAELAVSGARDGLERALRKG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
ERARVRRILGEVARDERVLGAAACDPEGALVASTSEYPEPFDCGRIRAHAAAGAAAPVTS
HHHHHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCHHH
AFEAPYGETRVHLTAVPLADEEGPLGFVALVHDMSWVATREEQTRGFLAVAFAIVALAAA
HHCCCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VATTLAARFSWRGWSAELQRVLRATWLMPGPSAPPRTRREFQPLLSDVRALVSELASEQS
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
EGRAGLWSPARLRDALARHLPGSEVIVVANREPYIHERRDGVLRVQHPASGLVTALEPVV
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCEEEEECCCCHHHHHHHHHH
QATGGTWIAHGSGAADREVVDRHARVRVPPDDPAYTLRRVWLTAAEEEGYYYGFSNEGLW
HHCCCEEEECCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHEECCCCEEEECCCCCCC
PLCHVAHTRPTFRGGDFAAYRDANRKFADAVCEEANGPDPVVLVQDYHFALLPRMIRERL
HHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHC
PRATIITFWHIPWPNSERFGICPWGPEILEGMLGSSILGFHVQAHCNNFLDSVDRYLEAR
CCEEEEEEEECCCCCCCCEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDRERQSVVLGGQETLIRAYPISIDWPTRWAADAPAAPLCRERVFADLGLAPDALLGVGI
HCCCHHHEEECCCHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCC
DRLDYTKGIEERLLAVERLLERFPQFRGRFTFAQLAAPSRTRIPRYQELNRNVEEVARRV
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHCCCHHHHHHHH
NERFGEGDYRPIVLLREHHEPPTVFRYYRAADLCYVSSLHDGMNLVAKEFVAARDDEAGV
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LVLSRFTGASRELGEALLVNPYDLEEASSALAAALAMPREEQRERMRALRTFVSEFNVYR
EEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WAGRMLVDAGRLRKRDRVSGRITVPFRTVPGEAGGRR
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRAVLKVLVPLMLLLGAIAWGASVLVEHTARRWFDRDTRMRAELAVSGARDGLERALRKG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
ERARVRRILGEVARDERVLGAAACDPEGALVASTSEYPEPFDCGRIRAHAAAGAAAPVTS
HHHHHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCCCHHH
AFEAPYGETRVHLTAVPLADEEGPLGFVALVHDMSWVATREEQTRGFLAVAFAIVALAAA
HHCCCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VATTLAARFSWRGWSAELQRVLRATWLMPGPSAPPRTRREFQPLLSDVRALVSELASEQS
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
EGRAGLWSPARLRDALARHLPGSEVIVVANREPYIHERRDGVLRVQHPASGLVTALEPVV
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCEEEEECCCCHHHHHHHHHH
QATGGTWIAHGSGAADREVVDRHARVRVPPDDPAYTLRRVWLTAAEEEGYYYGFSNEGLW
HHCCCEEEECCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHEECCCCEEEECCCCCCC
PLCHVAHTRPTFRGGDFAAYRDANRKFADAVCEEANGPDPVVLVQDYHFALLPRMIRERL
HHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHC
PRATIITFWHIPWPNSERFGICPWGPEILEGMLGSSILGFHVQAHCNNFLDSVDRYLEAR
CCEEEEEEEECCCCCCCCEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDRERQSVVLGGQETLIRAYPISIDWPTRWAADAPAAPLCRERVFADLGLAPDALLGVGI
HCCCHHHEEECCCHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCC
DRLDYTKGIEERLLAVERLLERFPQFRGRFTFAQLAAPSRTRIPRYQELNRNVEEVARRV
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEHHHHCCCCCCCCCCHHHHCCCHHHHHHHH
NERFGEGDYRPIVLLREHHEPPTVFRYYRAADLCYVSSLHDGMNLVAKEFVAARDDEAGV
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LVLSRFTGASRELGEALLVNPYDLEEASSALAAALAMPREEQRERMRALRTFVSEFNVYR
EEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
WAGRMLVDAGRLRKRDRVSGRITVPFRTVPGEAGGRR
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Monovalent cations [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; D-glucose 6-phosphate

Specific reaction: UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate

General reaction: Hexosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA