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The map label for this gene is pgl [H]

Identifier: 220917607

GI number: 220917607

Start: 2769129

End: 2769860

Strand: Reverse

Name: pgl [H]

Synonym: A2cp1_2507

Alternate gene names: 220917607

Gene position: 2769860-2769129 (Counterclockwise)

Preceding gene: 220917608

Following gene: 220917606

Centisome position: 55.07

GC content: 80.87

Gene sequence:

>732_bases
GTGGCGCGTCCCCCGGGGCCGGCGCTGGTGCGGGCCGCGGACGCGGCGGCCCTGGCGCGCGTGGCCGCCGAGGAGGTGGC
GCGGCGGGCCGAGGAGGCCGTCGCGGCGCGCGGGCGCTTCGCGATCGCGCTCGCCGGAGGAAGCACCCCGCGGGCGCTGT
ACGCGCTCCTCGCCGATCCCGCCGCGCCCTGGCGCGAGCGGGTGCCGTGGGCCCGCACCGAGATCTGGTTCGGCGACGAG
CGCTGCGTCCCGCCCGACCACCCCGACTCGAACTATCGGACCGCGGGCGAGGCGCTGCTGGAGCACGTCCCCGCCGCCGC
CGTGCATCGGATCGAGGGCGAGCGACCGCCCGCGGAGGCGGCCGCCGGCTACGAGGCGGCGCTGCGGCGGGCGGCCGATC
CCGACGGGAGCCCGCCGCGCCTCGACCTGGTGCTGCTCGGCCTCGGGGCCGACGGCCACACCGCGTCGCTGTTCCCGGGG
AGCCCCGCGCTCGACGAGCGCGCGCGCTGGGTGGCGGCGCCCTTCGTGCCCGCCGTCGGCGCCCACCGCATCACCCTCAC
GCTGCCGGTGCTGGAGCGGGCGCGCGCGATCGCGTTCCTCGTGTCCGGCGCCGAGAAGCGGGCGGCGCTCGGGCGGCTCC
TCGCCCCCGGCACGCCCTCGATCCCGGCGGCGCGGGTGCGTCCGCTCGACGGCGCGCTCCTCGTGCTGGCCGACCGCGCG
GCGGCAGGGTAG

Upstream 100 bases:

>100_bases
GCGACTTCCCGAACTACGCCGCGGGGAGCTGGGGGCCCGCGGCGGCGTCCGAGCTGCTCGCGCGCGACGGGCGGCGCTGG
GCGGACCGGGAGTGACCCCG

Downstream 100 bases:

>100_bases
GCGCTCGCCCGGTGGGCCTCCGGGCGGGCATCGGAGGGACCCCACGACCGTGCGTCCTCCTGGCGCAGGGTCCCCCGCAG
GCGGTTGGAGGGCCAACCGA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MARPPGPALVRAADAAALARVAAEEVARRAEEAVAARGRFAIALAGGSTPRALYALLADPAAPWRERVPWARTEIWFGDE
RCVPPDHPDSNYRTAGEALLEHVPAAAVHRIEGERPPAEAAAGYEAALRRAADPDGSPPRLDLVLLGLGADGHTASLFPG
SPALDERARWVAAPFVPAVGAHRITLTLPVLERARAIAFLVSGAEKRAALGRLLAPGTPSIPAARVRPLDGALLVLADRA
AAG

Sequences:

>Translated_243_residues
MARPPGPALVRAADAAALARVAAEEVARRAEEAVAARGRFAIALAGGSTPRALYALLADPAAPWRERVPWARTEIWFGDE
RCVPPDHPDSNYRTAGEALLEHVPAAAVHRIEGERPPAEAAAGYEAALRRAADPDGSPPRLDLVLLGLGADGHTASLFPG
SPALDERARWVAAPFVPAVGAHRITLTLPVLERARAIAFLVSGAEKRAALGRLLAPGTPSIPAARVRPLDGALLVLADRA
AAG
>Mature_242_residues
ARPPGPALVRAADAAALARVAAEEVARRAEEAVAARGRFAIALAGGSTPRALYALLADPAAPWRERVPWARTEIWFGDER
CVPPDHPDSNYRTAGEALLEHVPAAAVHRIEGERPPAEAAAGYEAALRRAADPDGSPPRLDLVLLGLGADGHTASLFPGS
PALDERARWVAAPFVPAVGAHRITLTLPVLERARAIAFLVSGAEKRAALGRLLAPGTPSIPAARVRPLDGALLVLADRAA
AG

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=247, Percent_Identity=40.4858299595142, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI52145310, Length=240, Percent_Identity=35.4166666666667, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI115533058, Length=244, Percent_Identity=31.5573770491803, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115533060, Length=244, Percent_Identity=31.5573770491803, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321957, Length=227, Percent_Identity=34.8017621145374, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321687, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319918, Length=200, Percent_Identity=33.5, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324362, Length=199, Percent_Identity=31.6582914572864, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24641119, Length=232, Percent_Identity=31.8965517241379, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25314; Mature: 25183

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPPGPALVRAADAAALARVAAEEVARRAEEAVAARGRFAIALAGGSTPRALYALLADP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC
AAPWRERVPWARTEIWFGDERCVPPDHPDSNYRTAGEALLEHVPAAAVHRIEGERPPAEA
CCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCHHH
AAGYEAALRRAADPDGSPPRLDLVLLGLGADGHTASLFPGSPALDERARWVAAPFVPAVG
HCCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEECCCCCCHHHHHHEECCCCCCCCC
AHRITLTLPVLERARAIAFLVSGAEKRAALGRLLAPGTPSIPAARVRPLDGALLVLADRA
CEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEEEECCC
AAG
CCC
>Mature Secondary Structure 
ARPPGPALVRAADAAALARVAAEEVARRAEEAVAARGRFAIALAGGSTPRALYALLADP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCC
AAPWRERVPWARTEIWFGDERCVPPDHPDSNYRTAGEALLEHVPAAAVHRIEGERPPAEA
CCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCHHH
AAGYEAALRRAADPDGSPPRLDLVLLGLGADGHTASLFPGSPALDERARWVAAPFVPAVG
HCCHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEECCCCCCHHHHHHEECCCCCCCCC
AHRITLTLPVLERARAIAFLVSGAEKRAALGRLLAPGTPSIPAARVRPLDGALLVLADRA
CEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEEEECCC
AAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]