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The map label for this gene is degP [H]

Identifier: 220917503

GI number: 220917503

Start: 2661344

End: 2662195

Strand: Reverse

Name: degP [H]

Synonym: A2cp1_2403

Alternate gene names: 220917503

Gene position: 2662195-2661344 (Counterclockwise)

Preceding gene: 220917504

Following gene: 220917501

Centisome position: 52.93

GC content: 76.64

Gene sequence:

>852_bases
GTGCCCCGCTATCGACTCCTCTCCAGCCTTGGCGGCGCGGCCCTGGTCGCCGGCCTCTTCCTCCTCGCCTCCCCGCTGCT
GGGGCTCACCACGCCGCGCGCGGGCAACCCGCGCGCCGAGACCGTGCACAAGGTCTTCCCCTCGGCGGTCCGGCTCCAGA
TCGTCGCCGGCGAGCAGGTGGTGCGGAGCGCCTCCGGCATCGCGTTCGCGCACGACGGCGGCCGCACGTACGTGCTCACC
AACGCGCACGTGGTCGAGCCGGCCCGCGAGTGGCCGGAGGGCGCGGCGCTGCGGGTGCTCCCCTCCGACGGCTCCGCCGG
CGTGGCGGCGAACGTGGTCGCGCGCGGGCGGGTGCCCGAGGCCGACCTGGCCGTCCTCGAGGTGCAGGCGACGCTGCCGG
TGACGCCGCTCGCGGGCGACGACCGGATGGAGCTCGGCGACGACCTGGTGGTGATCGGCGCGCCCTTCGGGAAGGGGCTG
TCGGTGGCGGCCGGGATCGTGTCGCAGGTCGAGTACGAGCTCGCCGAGAACGCCGCCGCCCCGCGGCGCGCCCGGGCGCT
CAAGACCGACGCGGCCATCGGCTACGGCAGCTCGGGCGGCGGCGTCTTCGACGTGCCGGGCGGCCGCCTCATCGGGCTGG
TCGAGGGGTACCGCACCGCGCGCGTCGCGTTCGGCAAGGACGCCGAGCAGTACGCGTTCGACGTCCCCATGCCCGGCGAG
ACGTTCGTCGCGCCGGCGGCGAAGATCCGCCGCTTCCTGGTCGAGAAGGGCCTCGGGCGGCTCGCGCCCGCCGAGGCCGT
GGCCGGCGCCCAGGGGCCGGTGGCCACGCCGGCCGCGGCGAAGCAGTTCTAG

Upstream 100 bases:

>100_bases
CGACGCGCCCGCCTGACGGCCGAGTGAGCGCACGCCGTGGTCGCGAGTCCGTCCGCAAAGGCGAGGGAATTGCCTGTTCG
GGTCCGCCGTTCCGGATTTC

Downstream 100 bases:

>100_bases
CGCGCCTGCGCCGGCCTTCCGGCGCGTCCTGCACCTGCCGTCACCGCCCGGGCCCGCCGGGCGGCGGGGAGGGCGGGCCG
GGCGAGGTGCTGCCCGGGGC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MPRYRLLSSLGGAALVAGLFLLASPLLGLTTPRAGNPRAETVHKVFPSAVRLQIVAGEQVVRSASGIAFAHDGGRTYVLT
NAHVVEPAREWPEGAALRVLPSDGSAGVAANVVARGRVPEADLAVLEVQATLPVTPLAGDDRMELGDDLVVIGAPFGKGL
SVAAGIVSQVEYELAENAAAPRRARALKTDAAIGYGSSGGGVFDVPGGRLIGLVEGYRTARVAFGKDAEQYAFDVPMPGE
TFVAPAAKIRRFLVEKGLGRLAPAEAVAGAQGPVATPAAAKQF

Sequences:

>Translated_283_residues
MPRYRLLSSLGGAALVAGLFLLASPLLGLTTPRAGNPRAETVHKVFPSAVRLQIVAGEQVVRSASGIAFAHDGGRTYVLT
NAHVVEPAREWPEGAALRVLPSDGSAGVAANVVARGRVPEADLAVLEVQATLPVTPLAGDDRMELGDDLVVIGAPFGKGL
SVAAGIVSQVEYELAENAAAPRRARALKTDAAIGYGSSGGGVFDVPGGRLIGLVEGYRTARVAFGKDAEQYAFDVPMPGE
TFVAPAAKIRRFLVEKGLGRLAPAEAVAGAQGPVATPAAAKQF
>Mature_282_residues
PRYRLLSSLGGAALVAGLFLLASPLLGLTTPRAGNPRAETVHKVFPSAVRLQIVAGEQVVRSASGIAFAHDGGRTYVLTN
AHVVEPAREWPEGAALRVLPSDGSAGVAANVVARGRVPEADLAVLEVQATLPVTPLAGDDRMELGDDLVVIGAPFGKGLS
VAAGIVSQVEYELAENAAAPRRARALKTDAAIGYGSSGGGVFDVPGGRLIGLVEGYRTARVAFGKDAEQYAFDVPMPGET
FVAPAAKIRRFLVEKGLGRLAPAEAVAGAQGPVATPAAAKQF

Specific function: Serine protease that is required at high temperature. Involved in the degradation of damaged proteins. Shared specificity with hhoA/degQ [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=239, Percent_Identity=29.2887029288703, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI24308541, Length=231, Percent_Identity=30.7359307359307, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1786356, Length=151, Percent_Identity=35.7615894039735, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 29049; Mature: 28917

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYRLLSSLGGAALVAGLFLLASPLLGLTTPRAGNPRAETVHKVFPSAVRLQIVAGEQV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEEECHHH
VRSASGIAFAHDGGRTYVLTNAHVVEPAREWPEGAALRVLPSDGSAGVAANVVARGRVPE
HHHCCCEEEEECCCEEEEEECCEEECCHHHCCCCCEEEEEECCCCCCEEEHEEECCCCCC
ADLAVLEVQATLPVTPLAGDDRMELGDDLVVIGAPFGKGLSVAAGIVSQVEYELAENAAA
CCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
PRRARALKTDAAIGYGSSGGGVFDVPGGRLIGLVEGYRTARVAFGKDAEQYAFDVPMPGE
CHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHEEEECCCCCC
TFVAPAAKIRRFLVEKGLGRLAPAEAVAGAQGPVATPAAAKQF
CEECCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
PRYRLLSSLGGAALVAGLFLLASPLLGLTTPRAGNPRAETVHKVFPSAVRLQIVAGEQV
CHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEEECHHH
VRSASGIAFAHDGGRTYVLTNAHVVEPAREWPEGAALRVLPSDGSAGVAANVVARGRVPE
HHHCCCEEEEECCCEEEEEECCEEECCHHHCCCCCEEEEEECCCCCCEEEHEEECCCCCC
ADLAVLEVQATLPVTPLAGDDRMELGDDLVVIGAPFGKGLSVAAGIVSQVEYELAENAAA
CCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
PRRARALKTDAAIGYGSSGGGVFDVPGGRLIGLVEGYRTARVAFGKDAEQYAFDVPMPGE
CHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHEEEECCCCCC
TFVAPAAKIRRFLVEKGLGRLAPAEAVAGAQGPVATPAAAKQF
CEECCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1645840; 11677609 [H]