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The map label for this gene is yacO [H]

Identifier: 220917468

GI number: 220917468

Start: 2626004

End: 2626774

Strand: Reverse

Name: yacO [H]

Synonym: A2cp1_2368

Alternate gene names: 220917468

Gene position: 2626774-2626004 (Counterclockwise)

Preceding gene: 220917469

Following gene: 220917467

Centisome position: 52.23

GC content: 76.13

Gene sequence:

>771_bases
ATGCGCGTCGTCTACGGCGTGAACCCGGTGCGCGAGCTGCTCCGCGCCGGGGGCGGCGACGTCGCCGAGGTGTGGCTGGC
CGAGGGCGGCACCCGCGGCGCCGCGTTCGCCGAGCTGGAACGGCTCGGGCGGGGGGCGGGCGCCAAGGTGCGCGCGGCGC
CCCGCGCCAAGCTCGACCGGCTGGCCGGCACCGACCGGCACCAGGGCGTCGTCGCGGTGGTGGCCGACTTCCGTTACGCG
GAGCTGGAGGATCTGCTCGCGCGCGCGCAGGCCGGCGGCCGCCCGCCGCTCCTGGTGGTGCTCGACGGCGTCGAGGACCC
GCACAACCTCGGCGCCATCATCCGCTCGGCGCACGCGCTCGGCTCGCACGGCGTCGTCATCCCGCGAGACCGCGCCGTGG
GCGTCACGCCCGCGGTCGCGAAGGCGTCGGCCGGCGCGGTGGAGCGCTGCCCGGTGGCGCGCGTCACCAACGTGGCGAAG
ACCCTCGAGCGGCTGAAGGAGGCGGGCATCTGGTCGGTCGCGCTCGCAGCGGACGGCGAACGCCCCCTCGGCGAGGTCGA
TCTCAAGGGCCCCACGGCGCTCGTCCTCGGCAGCGAGGGGGAGGGGATCCGGCCGCTGGTGCGCCGCACCTGCGACCTCT
CCGCGCGGATCCCCATGTCGGGTGATCTCGACAGCTTGTCGGTGTCCGCGTCGGCCGCGGTCGCCCTGTACGAGGCCGCG
CGGCAGCGCGCGGGGACGCCGTCGAAATCAGCGGTCGAAATGCGTCCTTGA

Upstream 100 bases:

>100_bases
CAGGAGGCGCGGGCGAAGGTGGACTTCTTCATCTGCTCCGACCAGTGGTGCGTGAAGCAGGCGCGCGACGTGTCGGTCCC
GGTCAAGGTCGAGTAGCGCG

Downstream 100 bases:

>100_bases
CAAGATGGGGCCACTCATTTTAAAGACCGCCCTCCACAACGGACGGCGGTGGGTTCGCCCGAGCCGTGCCCGAGGGACGA
CGGTCGTGGATTCGGGAAGG

Product: TrmH family RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRVVYGVNPVRELLRAGGGDVAEVWLAEGGTRGAAFAELERLGRGAGAKVRAAPRAKLDRLAGTDRHQGVVAVVADFRYA
ELEDLLARAQAGGRPPLLVVLDGVEDPHNLGAIIRSAHALGSHGVVIPRDRAVGVTPAVAKASAGAVERCPVARVTNVAK
TLERLKEAGIWSVALAADGERPLGEVDLKGPTALVLGSEGEGIRPLVRRTCDLSARIPMSGDLDSLSVSASAAVALYEAA
RQRAGTPSKSAVEMRP

Sequences:

>Translated_256_residues
MRVVYGVNPVRELLRAGGGDVAEVWLAEGGTRGAAFAELERLGRGAGAKVRAAPRAKLDRLAGTDRHQGVVAVVADFRYA
ELEDLLARAQAGGRPPLLVVLDGVEDPHNLGAIIRSAHALGSHGVVIPRDRAVGVTPAVAKASAGAVERCPVARVTNVAK
TLERLKEAGIWSVALAADGERPLGEVDLKGPTALVLGSEGEGIRPLVRRTCDLSARIPMSGDLDSLSVSASAAVALYEAA
RQRAGTPSKSAVEMRP
>Mature_256_residues
MRVVYGVNPVRELLRAGGGDVAEVWLAEGGTRGAAFAELERLGRGAGAKVRAAPRAKLDRLAGTDRHQGVVAVVADFRYA
ELEDLLARAQAGGRPPLLVVLDGVEDPHNLGAIIRSAHALGSHGVVIPRDRAVGVTPAVAKASAGAVERCPVARVTNVAK
TLERLKEAGIWSVALAADGERPLGEVDLKGPTALVLGSEGEGIRPLVRRTCDLSARIPMSGDLDSLSVSASAAVALYEAA
RQRAGTPSKSAVEMRP

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=268, Percent_Identity=32.8358208955224, Blast_Score=104, Evalue=9e-23,
Organism=Escherichia coli, GI1790623, Length=245, Percent_Identity=37.5510204081633, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1790083, Length=171, Percent_Identity=35.672514619883, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788935, Length=239, Percent_Identity=26.3598326359833, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555908, Length=257, Percent_Identity=28.7937743190661, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26575; Mature: 26575

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVYGVNPVRELLRAGGGDVAEVWLAEGGTRGAAFAELERLGRGAGAKVRAAPRAKLDR
CEEEECCCHHHHHHHCCCCCEEEHEECCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHH
LAGTDRHQGVVAVVADFRYAELEDLLARAQAGGRPPLLVVLDGVEDPHNLGAIIRSAHAL
HCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHC
GSHGVVIPRDRAVGVTPAVAKASAGAVERCPVARVTNVAKTLERLKEAGIWSVALAADGE
CCCCEEEECCCCCCCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
RPLGEVDLKGPTALVLGSEGEGIRPLVRRTCDLSARIPMSGDLDSLSVSASAAVALYEAA
CCCCCEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RQRAGTPSKSAVEMRP
HHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRVVYGVNPVRELLRAGGGDVAEVWLAEGGTRGAAFAELERLGRGAGAKVRAAPRAKLDR
CEEEECCCHHHHHHHCCCCCEEEHEECCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHH
LAGTDRHQGVVAVVADFRYAELEDLLARAQAGGRPPLLVVLDGVEDPHNLGAIIRSAHAL
HCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHC
GSHGVVIPRDRAVGVTPAVAKASAGAVERCPVARVTNVAKTLERLKEAGIWSVALAADGE
CCCCEEEECCCCCCCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
RPLGEVDLKGPTALVLGSEGEGIRPLVRRTCDLSARIPMSGDLDSLSVSASAAVALYEAA
CCCCCEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RQRAGTPSKSAVEMRP
HHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]