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The map label for this gene is yfhA [H]

Identifier: 220916726

GI number: 220916726

Start: 1813068

End: 1813451

Strand: Direct

Name: yfhA [H]

Synonym: A2cp1_1620

Alternate gene names: 220916726

Gene position: 1813068-1813451 (Clockwise)

Preceding gene: 220916725

Following gene: 220916727

Centisome position: 36.05

GC content: 72.92

Gene sequence:

>384_bases
ATGGAGCAGAGCGGGGTACGGGTCCTCCTCGTCGAGGACGACGACGACAACCGGGAGCTGATGGCGGAGGTGCTCACCGC
CTCCGGGTGCCTGGTCCTGTCCGCCGCGAGCGGGCAGGAGGGGCTGAAGACCCTGTCCGAGCACTCGATCGACGTGGTGG
TCACCGACGTCGGCATGCCCGGCATGGGCGGGCTGGAGATGGCCCGGGCGGCGAAGGCCATCGCGCCCACCGTCCCGGTG
GTCATCGTCACCGGCTGGGCGGAGCGCGACGACATCGCGCGGGCGCGCGGCCGCGACGTGGACGCGGTGCTCATCAAGCC
GGTGGACCCGGACGCGCTCACCGCCGCAGTGAACGACGCGGTGCAGACGCACGGGCGCGCGTAG

Upstream 100 bases:

>100_bases
CCGAGTAGCCGTCGCCCCCACGAGGCGGTCGCGCCCCGGGGCGCCGAGTGCTTAACTGACCCCGGGGTGCCAGGTCGCGC
GGCCGCCCGGCGAGGGGATC

Downstream 100 bases:

>100_bases
CGGCGGCCGGGCCGGCTTGACACTCCCGGATCCGCCCAATACGTTGCGCTCTCCCCAGGCTTGATTCTGGAATCAGCGGC
CGCCGAGCGGCTCCGAGGGT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MEQSGVRVLLVEDDDDNRELMAEVLTASGCLVLSAASGQEGLKTLSEHSIDVVVTDVGMPGMGGLEMARAAKAIAPTVPV
VIVTGWAERDDIARARGRDVDAVLIKPVDPDALTAAVNDAVQTHGRA

Sequences:

>Translated_127_residues
MEQSGVRVLLVEDDDDNRELMAEVLTASGCLVLSAASGQEGLKTLSEHSIDVVVTDVGMPGMGGLEMARAAKAIAPTVPV
VIVTGWAERDDIARARGRDVDAVLIKPVDPDALTAAVNDAVQTHGRA
>Mature_127_residues
MEQSGVRVLLVEDDDDNRELMAEVLTASGCLVLSAASGQEGLKTLSEHSIDVVVTDVGMPGMGGLEMARAAKAIAPTVPV
VIVTGWAERDDIARARGRDVDAVLIKPVDPDALTAAVNDAVQTHGRA

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=35.2459016393443, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=106, Percent_Identity=33.9622641509434, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=30.952380952381, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.1475409836066, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 13231; Mature: 13231

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSGVRVLLVEDDDDNRELMAEVLTASGCLVLSAASGQEGLKTLSEHSIDVVVTDVGMP
CCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCEEEEEEECCCC
GMGGLEMARAAKAIAPTVPVVIVTGWAERDDIARARGRDVDAVLIKPVDPDALTAAVNDA
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
VQTHGRA
HHHCCCC
>Mature Secondary Structure
MEQSGVRVLLVEDDDDNRELMAEVLTASGCLVLSAASGQEGLKTLSEHSIDVVVTDVGMP
CCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCEEEEEEECCCC
GMGGLEMARAAKAIAPTVPVVIVTGWAERDDIARARGRDVDAVLIKPVDPDALTAAVNDA
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
VQTHGRA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]