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The map label for this gene is tolQ [H]

Identifier: 220916712

GI number: 220916712

Start: 1795073

End: 1795738

Strand: Reverse

Name: tolQ [H]

Synonym: A2cp1_1606

Alternate gene names: 220916712

Gene position: 1795738-1795073 (Counterclockwise)

Preceding gene: 220916713

Following gene: 220916711

Centisome position: 35.71

GC content: 77.03

Gene sequence:

>666_bases
ATGACGAACGCACTGTTCCACCTGTTCACCCGCGCCGGCGCGGAGTGGGTGATGTTCCTGCTCGCCGCGCTCTCCGTGGC
GTCGGTGACGCTGATCCTCGAGCGGCTCGCCTGGTTCGCGCGGCGCCGCGCGCCGGTCCCGGGGCTGCTGCCGCTGCTGC
GCGCGGGGCGCCTGGAGGAGGCGCGGCTCCGGGTCGGGCAGCTGCGGGGCCTCGAGGCCGAGGTGGCGCGCGCCGCCATC
GACGCCGCCGAGGGCGGCCCGGCGTCGGTGCACGAGGCGGTCGCGTGCGCGATCGCCGAGGCGCGGCCCGGCTACGAGCG
CGCGCTGTCGTTCCTCGGGACGCTCGGGAACAACGCCCCCTTCCTCGGGCTGTTCGGCACCGTGATCGGCGTCATCCAGG
CGTTCTCCGACCTGGCGGTGGGCGGGCCACGGGGCGCGGGCGCCGCGGCGGTGATGGCCGGCATCTCGGAGGCCCTGGTC
GCGACCGCGGCGGGCATCCTGGTGGCGATCCCGGCGGTGGTCGCGTTCAACGGCTACCAGCGCTGGCTGAAGGCGTTGGT
GCAGCGGGCGGAGGCGATCGAGCACGCGCTCGCCGCCCACCTCGAGCGCGACGAGGTCCGCCAGGCCGCGCTGGCGCGGG
CGCGCCCGCCCGTCACCGCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGGGCCGGAGCTCCTGCGCGCCCGCGGTAGCGCGGCCGCGGGGCAGCGGTGTTTCGCGCTCGACGGCGGCCGCAGGCG
CGGTCGCCCCGGAGCGAGAC

Downstream 100 bases:

>100_bases
CCCGGAGCCCGCCATGGCCGCGCACTCCAACGACCCCGACGACGCGATCACCGGCATCAACGTGACGCCGCTGGTGGACG
TCACGCTGGTGCTGCTGGTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTNALFHLFTRAGAEWVMFLLAALSVASVTLILERLAWFARRRAPVPGLLPLLRAGRLEEARLRVGQLRGLEAEVARAAI
DAAEGGPASVHEAVACAIAEARPGYERALSFLGTLGNNAPFLGLFGTVIGVIQAFSDLAVGGPRGAGAAAVMAGISEALV
ATAAGILVAIPAVVAFNGYQRWLKALVQRAEAIEHALAAHLERDEVRQAALARARPPVTAA

Sequences:

>Translated_221_residues
MTNALFHLFTRAGAEWVMFLLAALSVASVTLILERLAWFARRRAPVPGLLPLLRAGRLEEARLRVGQLRGLEAEVARAAI
DAAEGGPASVHEAVACAIAEARPGYERALSFLGTLGNNAPFLGLFGTVIGVIQAFSDLAVGGPRGAGAAAVMAGISEALV
ATAAGILVAIPAVVAFNGYQRWLKALVQRAEAIEHALAAHLERDEVRQAALARARPPVTAA
>Mature_220_residues
TNALFHLFTRAGAEWVMFLLAALSVASVTLILERLAWFARRRAPVPGLLPLLRAGRLEEARLRVGQLRGLEAEVARAAID
AAEGGPASVHEAVACAIAEARPGYERALSFLGTLGNNAPFLGLFGTVIGVIQAFSDLAVGGPRGAGAAAVMAGISEALVA
TAAGILVAIPAVVAFNGYQRWLKALVQRAEAIEHALAAHLERDEVRQAALARARPPVTAA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=222, Percent_Identity=28.8288288288288, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789381, Length=75, Percent_Identity=44, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23055; Mature: 22924

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNALFHLFTRAGAEWVMFLLAALSVASVTLILERLAWFARRRAPVPGLLPLLRAGRLEE
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHH
ARLRVGQLRGLEAEVARAAIDAAEGGPASVHEAVACAIAEARPGYERALSFLGTLGNNAP
HHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
FLGLFGTVIGVIQAFSDLAVGGPRGAGAAAVMAGISEALVATAAGILVAIPAVVAFNGYQ
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWLKALVQRAEAIEHALAAHLERDEVRQAALARARPPVTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TNALFHLFTRAGAEWVMFLLAALSVASVTLILERLAWFARRRAPVPGLLPLLRAGRLEE
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHH
ARLRVGQLRGLEAEVARAAIDAAEGGPASVHEAVACAIAEARPGYERALSFLGTLGNNAP
HHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
FLGLFGTVIGVIQAFSDLAVGGPRGAGAAAVMAGISEALVATAAGILVAIPAVVAFNGYQ
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWLKALVQRAEAIEHALAAHLERDEVRQAALARARPPVTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]