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The map label for this gene is yhfN [H]

Identifier: 220916713

GI number: 220916713

Start: 1795902

End: 1797152

Strand: Reverse

Name: yhfN [H]

Synonym: A2cp1_1607

Alternate gene names: 220916713

Gene position: 1797152-1795902 (Counterclockwise)

Preceding gene: 220916720

Following gene: 220916712

Centisome position: 35.73

GC content: 73.86

Gene sequence:

>1251_bases
ATGGGACCGCTGGTCGTGCCCGTCTTCCTGGCGCTGTTCGCCGTCCAGCTGGCGGTGGAGACCGGCCTGCTCGCGCTCAA
CCTCCGCCACGTCCGGCGCGAGCGGGGCGTGCCGTCGCCGCTCGCGGGCCAGGTGAGCGACGAGACCGCGGCGCGGAGCC
GCGCCTACACGCTCGCGAACGGGCGGCTGGCGCTCGTGGACGGGCTGTTCTCGGCGGCGGCCACGCTCGCGGTGCTGTTC
TCGGGCCTGCTGCCCTGGCTCGACCGCGCCGTCTCGGCGCGCCTGGCGGGTCCCCACCGCTTCGTGGCGTACCTGATGCT
GCTCGCCATGGGGGGCGCCGCGATCGCGCTCCCCTTCTCCGCCTGGCGCACGTTCGTCACCGAGGCCCGCTTCGGCTTCA
ACCGGACCAGCCTGGCGACCTGGCTCGGCGACCGCGCCCGGGGCGTCGCGCTCCAGGCGCTGATCGGGATCCCCGTCCTC
TACGCGGTCTACGGGTTCATGCGCTTCGCCGGCGCGCACTGGTGGCTGTGGCTGTTCGCGTTCCTGGTGGTGGTGCAGGT
GCTGCTGCTCTGGGCCTGGCCCACGCTCATCGCGCCGCTGTTCAACCGGTTCCAGCCGCTGCCGGAGGGGCCGCTCCGCG
ACCGGCTCGACGCGCTGGCGCGCGAGGCGGGGTTCGCGAACCGGGGGCTGTTCGTGATGGACGCGTCGCGCCGCTCCGGC
CACTCGAACGCGTACTTCACCGGGATCTTCCGGCCGCGCATCGTGCTGTTCGACACGCTGGTGGCGAGCATGAGCGTGGA
CGAGGCGGCGAGCGTGCTGGCGCACGAGATCGGCCACTACCGGCGGCACCACGTGCACCGCGGCCTGGCGCTGTCGCTCG
CCGGCACGCTCGTCATGCTGTTCGTGCTCTCGCGGATCGTGCCGTGGCCGCCGCTCTACACCGCCTTCGGCTTCGACGGC
CCCTCGCTCCACGCGGCGGTCGCGCTGCTCTCGCTGTGCGGCGGCGCGTTCGTGTTCTGGCTCGCGCCGCTCGCGGCGCA
GATGTCCCGACGCCACGAGTACGAGGCGGACCGCTACGCGATCGCGCTGGCGCGGGCCCCGGACGCGCTCGCGAGCGCGC
TGGTGCGGCTGAACGGCGAGAACCTCTCCAACCTGCACCCGCACCCCTGGTACAGCGCCTGGCACTACAGCCACCCGACC
CTGGTCGAGCGGCTCGAGGCCATCCGCTCCCAGCCCGCCCCGGCCCGCTGA

Upstream 100 bases:

>100_bases
AGGGCGTCCACCCGGCGAGTCTAACCGGACCGGCCGGGCGGCGCGGCGGGACGGCGGGGCCGGCTGCGCGCGCGGCGGGG
CCGGTGTATGACGGGAGGTC

Downstream 100 bases:

>100_bases
GGCTCCGCGGCGCCCACCGGGCGATCACCGCCAGCGCCCGGACCGCCGCCCGCCTCCCGGAGGGTCGGGCCGGAGCTCCT
GCGCGCCCGCGGTAGCGCGG

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MGPLVVPVFLALFAVQLAVETGLLALNLRHVRRERGVPSPLAGQVSDETAARSRAYTLANGRLALVDGLFSAAATLAVLF
SGLLPWLDRAVSARLAGPHRFVAYLMLLAMGGAAIALPFSAWRTFVTEARFGFNRTSLATWLGDRARGVALQALIGIPVL
YAVYGFMRFAGAHWWLWLFAFLVVVQVLLLWAWPTLIAPLFNRFQPLPEGPLRDRLDALAREAGFANRGLFVMDASRRSG
HSNAYFTGIFRPRIVLFDTLVASMSVDEAASVLAHEIGHYRRHHVHRGLALSLAGTLVMLFVLSRIVPWPPLYTAFGFDG
PSLHAAVALLSLCGGAFVFWLAPLAAQMSRRHEYEADRYAIALARAPDALASALVRLNGENLSNLHPHPWYSAWHYSHPT
LVERLEAIRSQPAPAR

Sequences:

>Translated_416_residues
MGPLVVPVFLALFAVQLAVETGLLALNLRHVRRERGVPSPLAGQVSDETAARSRAYTLANGRLALVDGLFSAAATLAVLF
SGLLPWLDRAVSARLAGPHRFVAYLMLLAMGGAAIALPFSAWRTFVTEARFGFNRTSLATWLGDRARGVALQALIGIPVL
YAVYGFMRFAGAHWWLWLFAFLVVVQVLLLWAWPTLIAPLFNRFQPLPEGPLRDRLDALAREAGFANRGLFVMDASRRSG
HSNAYFTGIFRPRIVLFDTLVASMSVDEAASVLAHEIGHYRRHHVHRGLALSLAGTLVMLFVLSRIVPWPPLYTAFGFDG
PSLHAAVALLSLCGGAFVFWLAPLAAQMSRRHEYEADRYAIALARAPDALASALVRLNGENLSNLHPHPWYSAWHYSHPT
LVERLEAIRSQPAPAR
>Mature_415_residues
GPLVVPVFLALFAVQLAVETGLLALNLRHVRRERGVPSPLAGQVSDETAARSRAYTLANGRLALVDGLFSAAATLAVLFS
GLLPWLDRAVSARLAGPHRFVAYLMLLAMGGAAIALPFSAWRTFVTEARFGFNRTSLATWLGDRARGVALQALIGIPVLY
AVYGFMRFAGAHWWLWLFAFLVVVQVLLLWAWPTLIAPLFNRFQPLPEGPLRDRLDALAREAGFANRGLFVMDASRRSGH
SNAYFTGIFRPRIVLFDTLVASMSVDEAASVLAHEIGHYRRHHVHRGLALSLAGTLVMLFVLSRIVPWPPLYTAFGFDGP
SLHAAVALLSLCGGAFVFWLAPLAAQMSRRHEYEADRYAIALARAPDALASALVRLNGENLSNLHPHPWYSAWHYSHPTL
VERLEAIRSQPAPAR

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=441, Percent_Identity=30.6122448979592, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17505484, Length=442, Percent_Identity=26.2443438914027, Blast_Score=150, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6322577, Length=404, Percent_Identity=36.1386138613861, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI19922414, Length=429, Percent_Identity=30.5361305361305, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI78707252, Length=399, Percent_Identity=25.31328320802, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78707254, Length=399, Percent_Identity=25.31328320802, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24654305, Length=425, Percent_Identity=24.4705882352941, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 45737; Mature: 45606

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLVVPVFLALFAVQLAVETGLLALNLRHVRRERGVPSPLAGQVSDETAARSRAYTLAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEECC
GRLALVDGLFSAAATLAVLFSGLLPWLDRAVSARLAGPHRFVAYLMLLAMGGAAIALPFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHHHH
AWRTFVTEARFGFNRTSLATWLGDRARGVALQALIGIPVLYAVYGFMRFAGAHWWLWLFA
HHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVVVQVLLLWAWPTLIAPLFNRFQPLPEGPLRDRLDALAREAGFANRGLFVMDASRRSG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
HSNAYFTGIFRPRIVLFDTLVASMSVDEAASVLAHEIGHYRRHHVHRGLALSLAGTLVML
CCCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSRIVPWPPLYTAFGFDGPSLHAAVALLSLCGGAFVFWLAPLAAQMSRRHEYEADRYA
HHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
IALARAPDALASALVRLNGENLSNLHPHPWYSAWHYSHPTLVERLEAIRSQPAPAR
EEHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GPLVVPVFLALFAVQLAVETGLLALNLRHVRRERGVPSPLAGQVSDETAARSRAYTLAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEECC
GRLALVDGLFSAAATLAVLFSGLLPWLDRAVSARLAGPHRFVAYLMLLAMGGAAIALPFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHHHH
AWRTFVTEARFGFNRTSLATWLGDRARGVALQALIGIPVLYAVYGFMRFAGAHWWLWLFA
HHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVVVQVLLLWAWPTLIAPLFNRFQPLPEGPLRDRLDALAREAGFANRGLFVMDASRRSG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
HSNAYFTGIFRPRIVLFDTLVASMSVDEAASVLAHEIGHYRRHHVHRGLALSLAGTLVML
CCCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSRIVPWPPLYTAFGFDGPSLHAAVALLSLCGGAFVFWLAPLAAQMSRRHEYEADRYA
HHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
IALARAPDALASALVRLNGENLSNLHPHPWYSAWHYSHPTLVERLEAIRSQPAPAR
EEHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]