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The map label for this gene is scoA [H]

Identifier: 220916701

GI number: 220916701

Start: 1783029

End: 1783730

Strand: Direct

Name: scoA [H]

Synonym: A2cp1_1595

Alternate gene names: 220916701

Gene position: 1783029-1783730 (Clockwise)

Preceding gene: 220916700

Following gene: 220916702

Centisome position: 35.45

GC content: 70.51

Gene sequence:

>702_bases
ATGAACAAGCTGGTCGAGTCGGCCGACGCCGCGGTCGCGGACGTGAAGGACGGGGCCACCATCATGGTGGGCGGGTTCGG
CCTGTGCGGGAACCCGGAGAACCTCATCCTCGCGCTCCACCGCAAGGGCGTGCGCGACCTCGTGCTCGTCTCGAACAACT
GCGGCACGACCGAGCTCGGGCTGGGCGTGCTGCTGAAGGCGCGGCAGATCCGCAAGATCGTCGCGTCGTACGTGGGCGAG
AACAAGGAGTTCGAGCGGCAGTTCCTCTCCGGCGAGCTGGAGGTGGAGCTGGTGCCGCAGGGCACGCTCGCCGAGCGCAT
CCGCGCCGGCGGCGCCGGCATCGGCGGCTTCTACACCGCCACGGGCGTCGGCACGCAGGTGGCGGAGGGCAAGGAGACGC
GGCTGCTCTCCGGCCGCGAGTACCTGCTGGAGTTGCCGCTCAAGGCCGACTTCGCGTTCCTGAAGGCCTGGAAGGCCGAC
ACCTGGGGCAACCTCGTGTACCGGAAGACCACCCGCAACTTCCAGCCGATGATGGCCGCCGCGGCGGCGGTCACGGTGGC
GGAGGCGGAGGAGGTGGTCGAGCCGGGCGCGCTCGACCCGGACCGGATCCACACGCCCAGCATCTACGTGAGGCGGGTGG
TCCGCGGGGAGCGGTACGAGAAGTGGATCGAGCGGCGGACGATCCGTCCGGCGACGGCGTAG

Upstream 100 bases:

>100_bases
TCCAGGCCATGAAGGACCTCGATCGCCGGCGCGGCCTGGCGTCGCTCTGCATCGGCGGCGGCGAGGCCGTCGCGCTCGTG
GTGGAGCGGTAGGAGGGCGG

Downstream 100 bases:

>100_bases
GGAGGATCGGAACGATGCCGCTCAAGCGAGAGCAGATCGCCGCGCGCGTGGCCCGCGAGCTCCGCGACGGCTTCTACGTG
AACCTCGGCATCGGGATGCC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNKLVESADAAVADVKDGATIMVGGFGLCGNPENLILALHRKGVRDLVLVSNNCGTTELGLGVLLKARQIRKIVASYVGE
NKEFERQFLSGELEVELVPQGTLAERIRAGGAGIGGFYTATGVGTQVAEGKETRLLSGREYLLELPLKADFAFLKAWKAD
TWGNLVYRKTTRNFQPMMAAAAAVTVAEAEEVVEPGALDPDRIHTPSIYVRRVVRGERYEKWIERRTIRPATA

Sequences:

>Translated_233_residues
MNKLVESADAAVADVKDGATIMVGGFGLCGNPENLILALHRKGVRDLVLVSNNCGTTELGLGVLLKARQIRKIVASYVGE
NKEFERQFLSGELEVELVPQGTLAERIRAGGAGIGGFYTATGVGTQVAEGKETRLLSGREYLLELPLKADFAFLKAWKAD
TWGNLVYRKTTRNFQPMMAAAAAVTVAEAEEVVEPGALDPDRIHTPSIYVRRVVRGERYEKWIERRTIRPATA
>Mature_233_residues
MNKLVESADAAVADVKDGATIMVGGFGLCGNPENLILALHRKGVRDLVLVSNNCGTTELGLGVLLKARQIRKIVASYVGE
NKEFERQFLSGELEVELVPQGTLAERIRAGGAGIGGFYTATGVGTQVAEGKETRLLSGREYLLELPLKADFAFLKAWKAD
TWGNLVYRKTTRNFQPMMAAAAAVTVAEAEEVVEPGALDPDRIHTPSIYVRRVVRGERYEKWIERRTIRPATA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=237, Percent_Identity=56.1181434599156, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI11545841, Length=235, Percent_Identity=56.1702127659575, Blast_Score=249, Evalue=2e-66,
Organism=Escherichia coli, GI1788551, Length=213, Percent_Identity=48.8262910798122, Blast_Score=208, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17531517, Length=257, Percent_Identity=49.4163424124514, Blast_Score=253, Evalue=5e-68,
Organism=Drosophila melanogaster, GI21358325, Length=244, Percent_Identity=52.8688524590164, Blast_Score=253, Evalue=8e-68,
Organism=Drosophila melanogaster, GI24655794, Length=244, Percent_Identity=52.8688524590164, Blast_Score=253, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25416; Mature: 25416

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVESADAAVADVKDGATIMVGGFGLCGNPENLILALHRKGVRDLVLVSNNCGTTELG
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCCCCHHHH
LGVLLKARQIRKIVASYVGENKEFERQFLSGELEVELVPQGTLAERIRAGGAGIGGFYTA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCEEC
TGVGTQVAEGKETRLLSGREYLLELPLKADFAFLKAWKADTWGNLVYRKTTRNFQPMMAA
CCCCCHHCCCCCCEECCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
AAAVTVAEAEEVVEPGALDPDRIHTPSIYVRRVVRGERYEKWIERRTIRPATA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKLVESADAAVADVKDGATIMVGGFGLCGNPENLILALHRKGVRDLVLVSNNCGTTELG
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCCCCHHHH
LGVLLKARQIRKIVASYVGENKEFERQFLSGELEVELVPQGTLAERIRAGGAGIGGFYTA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCEEC
TGVGTQVAEGKETRLLSGREYLLELPLKADFAFLKAWKADTWGNLVYRKTTRNFQPMMAA
CCCCCHHCCCCCCEECCCCCEEEECCCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
AAAVTVAEAEEVVEPGALDPDRIHTPSIYVRRVVRGERYEKWIERRTIRPATA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]