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The map label for this gene is soxB [H]

Identifier: 220916581

GI number: 220916581

Start: 1645427

End: 1646929

Strand: Reverse

Name: soxB [H]

Synonym: A2cp1_1475

Alternate gene names: 220916581

Gene position: 1646929-1645427 (Counterclockwise)

Preceding gene: 220916582

Following gene: 220916580

Centisome position: 32.75

GC content: 75.25

Gene sequence:

>1503_bases
GTGGGTAAGCGGCTGGTGTGCGCGTGCGAGGACGTGTCGCTGGAGGAGGTGCGCCGCGCGTTCGCGGCGGGCCACCGCGA
CCTCGAGTCGGTGAAGCGGGTCACCGGGCTCGGCACCGGGCCATGCCAGGGCAAGTCCTGCGTGACGCGCGTCGCGCAGG
AGCTGCTCCGGCTCGGGGCCACGCCGGCCGAGATCCAGCCGTTCACCGCCCGCACCCCGGTCCAGCCGGTGCCGCTCGCG
GCGCTGGCCGCGCTCGATCCCGCCGGGCTGCCGCTCGACGACGGCGTGCCGCTCCCGCCGCCCGCCGCGGATGCCTCGTC
GGGCCCGCCCTCCCCGGCCGCGCACCCGCAGCCGGACCCGCTCCCGGCCCGCGCGGACGTGGTGATCGTGGGCGGCGGGA
TCCAGGGGCTGGCGATCGCGTACGAGCTGGCGCGGCGGGGCGTGCGCGACGTGCTGGTGCTGGAGCAGGGATACCTGAAC
GCCGGCGCCTCCGGGCGGAACGGCGGCGGGGTCCGCGCGCAGTGGACCACCCCGACCATGATCCGCCTCGCCCGCCGCTC
GCTCGAGCTGTGCGACCGGTTCGCGGTGGAGATGGGCATCAACGTCTGGTTCCGCCGCAGCGGCTACCTGTTCCTCGCGC
CCACCGCCGAGCAGGTGACGCGGATCGAGAAGAACGCCGAGCTGCACCGGCGCGAGGGGCTGCGCACCCGGGTGATCGGG
CCGGACGAGGCGCTGCAGGTGGTGCCGGAGCTGGACCCGCGCCGGTTCCGCGCCGCGGCCTGGAACCCGGACGACGGCGT
GGTGTTCCCCTGGCCGTTCCTGTGGGGCTACGCGTCGCGGGCCGAGGCGCTCGGCGCGAAGGTCCGGACGTTCACCCGCG
TCACGGGCTTCGACACCGCGGGCGCGCGCGTGACCGCGGTGCGCACCGATCGCGGCCGGGTGGCGTGCGAGCTGGTGGTG
GTGGCCGCCGGCGCGTGGTCTCGCGACGTGGCCGCGCTCGCCGGGGTCTCGCTCCCGAACCGCCCCACCCGCCACGAGAT
CCTGGTGACCGAGCCGCTCAAGCCCTGGCTCGGGCCGCTCGTGTCCGTGCTGGGGAACGGCCTGTACTTCTCGCAGTCGC
AGCGCGGCGAGATCGTGGGCGGCATGGGCGATCCCGAGGAGCCCGAGGGCGTGGTGCAGGGCTCGACCCTGCGCTTCCTG
GCCCGCTTCGCCCGCGCCGCGGTGGAGACCGTGCCGCGGCTCGGCGAGGTGAAGGTGATCCGCCAGTGGGCGGGCTGCTA
CGACGTCACCCCGGACAACAACCCGGTGCTGGGCCCGGCCGGCTTCGAGAACTTCCACCAGTGCTCCGGCTTCGTCGGGC
ACGGGTTCATGATGGCGCCGGCGGTGGCCGAGCGGTACGCGGACTGGCTCGCCGGCCGGGGCAAGGACGAGATCTTCGAG
CGCTTCACCCTGGGCCGATTCGAGTCCGGCGCGGTCGCCCGGGAGGACTTCATCATCGGGTAG

Upstream 100 bases:

>100_bases
CACACGGGGGTCCCGGGGCTCCTCGCCGCGGGCGAGGTGACCGGGGCGATGGACGCGGCGCGCGCGGCCGAGGCCGGGCG
GCGCGCGGGGGAGGCGGCCC

Downstream 100 bases:

>100_bases
CGGTAATCTGCCCGGATGCCACTCGGGAAGAAGATCGCGTTCCTCGGGACGGGGAACATGGCCGAGGCCCTGGTGAAGGG
CCTGCTGCGGGCCGGGACCG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MGKRLVCACEDVSLEEVRRAFAAGHRDLESVKRVTGLGTGPCQGKSCVTRVAQELLRLGATPAEIQPFTARTPVQPVPLA
ALAALDPAGLPLDDGVPLPPPAADASSGPPSPAAHPQPDPLPARADVVIVGGGIQGLAIAYELARRGVRDVLVLEQGYLN
AGASGRNGGGVRAQWTTPTMIRLARRSLELCDRFAVEMGINVWFRRSGYLFLAPTAEQVTRIEKNAELHRREGLRTRVIG
PDEALQVVPELDPRRFRAAAWNPDDGVVFPWPFLWGYASRAEALGAKVRTFTRVTGFDTAGARVTAVRTDRGRVACELVV
VAAGAWSRDVAALAGVSLPNRPTRHEILVTEPLKPWLGPLVSVLGNGLYFSQSQRGEIVGGMGDPEEPEGVVQGSTLRFL
ARFARAAVETVPRLGEVKVIRQWAGCYDVTPDNNPVLGPAGFENFHQCSGFVGHGFMMAPAVAERYADWLAGRGKDEIFE
RFTLGRFESGAVAREDFIIG

Sequences:

>Translated_500_residues
MGKRLVCACEDVSLEEVRRAFAAGHRDLESVKRVTGLGTGPCQGKSCVTRVAQELLRLGATPAEIQPFTARTPVQPVPLA
ALAALDPAGLPLDDGVPLPPPAADASSGPPSPAAHPQPDPLPARADVVIVGGGIQGLAIAYELARRGVRDVLVLEQGYLN
AGASGRNGGGVRAQWTTPTMIRLARRSLELCDRFAVEMGINVWFRRSGYLFLAPTAEQVTRIEKNAELHRREGLRTRVIG
PDEALQVVPELDPRRFRAAAWNPDDGVVFPWPFLWGYASRAEALGAKVRTFTRVTGFDTAGARVTAVRTDRGRVACELVV
VAAGAWSRDVAALAGVSLPNRPTRHEILVTEPLKPWLGPLVSVLGNGLYFSQSQRGEIVGGMGDPEEPEGVVQGSTLRFL
ARFARAAVETVPRLGEVKVIRQWAGCYDVTPDNNPVLGPAGFENFHQCSGFVGHGFMMAPAVAERYADWLAGRGKDEIFE
RFTLGRFESGAVAREDFIIG
>Mature_499_residues
GKRLVCACEDVSLEEVRRAFAAGHRDLESVKRVTGLGTGPCQGKSCVTRVAQELLRLGATPAEIQPFTARTPVQPVPLAA
LAALDPAGLPLDDGVPLPPPAADASSGPPSPAAHPQPDPLPARADVVIVGGGIQGLAIAYELARRGVRDVLVLEQGYLNA
GASGRNGGGVRAQWTTPTMIRLARRSLELCDRFAVEMGINVWFRRSGYLFLAPTAEQVTRIEKNAELHRREGLRTRVIGP
DEALQVVPELDPRRFRAAAWNPDDGVVFPWPFLWGYASRAEALGAKVRTFTRVTGFDTAGARVTAVRTDRGRVACELVVV
AAGAWSRDVAALAGVSLPNRPTRHEILVTEPLKPWLGPLVSVLGNGLYFSQSQRGEIVGGMGDPEEPEGVVQGSTLRFLA
RFARAAVETVPRLGEVKVIRQWAGCYDVTPDNNPVLGPAGFENFHQCSGFVGHGFMMAPAVAERYADWLAGRGKDEIFER
FTLGRFESGAVAREDFIIG

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=369, Percent_Identity=27.6422764227642, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI8923708, Length=428, Percent_Identity=29.6728971962617, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI194306651, Length=399, Percent_Identity=25.31328320802, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI197927446, Length=385, Percent_Identity=24.6753246753247, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI21361378, Length=385, Percent_Identity=24.6753246753247, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1787438, Length=324, Percent_Identity=25.3086419753086, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994045, Length=366, Percent_Identity=24.5901639344262, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994052, Length=373, Percent_Identity=23.8605898123324, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20130091, Length=381, Percent_Identity=27.5590551181102, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129729, Length=391, Percent_Identity=29.6675191815857, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571104, Length=268, Percent_Identity=27.2388059701493, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 53785; Mature: 53654

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRLVCACEDVSLEEVRRAFAAGHRDLESVKRVTGLGTGPCQGKSCVTRVAQELLRLGA
CCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
TPAEIQPFTARTPVQPVPLAALAALDPAGLPLDDGVPLPPPAADASSGPPSPAAHPQPDP
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPARADVVIVGGGIQGLAIAYELARRGVRDVLVLEQGYLNAGASGRNGGGVRAQWTTPTM
CCCCCCEEEECCCCHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCEEEEECCHHH
IRLARRSLELCDRFAVEMGINVWFRRSGYLFLAPTAEQVTRIEKNAELHRREGLRTRVIG
HHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHCCCEEEECC
PDEALQVVPELDPRRFRAAAWNPDDGVVFPWPFLWGYASRAEALGAKVRTFTRVTGFDTA
CHHHHHHCCCCCCHHEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHEECCCCCC
GARVTAVRTDRGRVACELVVVAAGAWSRDVAALAGVSLPNRPTRHEILVTEPLKPWLGPL
CCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHH
VSVLGNGLYFSQSQRGEIVGGMGDPEEPEGVVQGSTLRFLARFARAAVETVPRLGEVKVI
HHHHCCCEEECCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RQWAGCYDVTPDNNPVLGPAGFENFHQCSGFVGHGFMMAPAVAERYADWLAGRGKDEIFE
HHHHCEECCCCCCCCEECCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCHHHHHH
RFTLGRFESGAVAREDFIIG
HHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GKRLVCACEDVSLEEVRRAFAAGHRDLESVKRVTGLGTGPCQGKSCVTRVAQELLRLGA
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
TPAEIQPFTARTPVQPVPLAALAALDPAGLPLDDGVPLPPPAADASSGPPSPAAHPQPDP
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPARADVVIVGGGIQGLAIAYELARRGVRDVLVLEQGYLNAGASGRNGGGVRAQWTTPTM
CCCCCCEEEECCCCHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCCCCCCEEEEECCHHH
IRLARRSLELCDRFAVEMGINVWFRRSGYLFLAPTAEQVTRIEKNAELHRREGLRTRVIG
HHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHCCCEEEECC
PDEALQVVPELDPRRFRAAAWNPDDGVVFPWPFLWGYASRAEALGAKVRTFTRVTGFDTA
CHHHHHHCCCCCCHHEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHEECCCCCC
GARVTAVRTDRGRVACELVVVAAGAWSRDVAALAGVSLPNRPTRHEILVTEPLKPWLGPL
CCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHH
VSVLGNGLYFSQSQRGEIVGGMGDPEEPEGVVQGSTLRFLARFARAAVETVPRLGEVKVI
HHHHCCCEEECCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RQWAGCYDVTPDNNPVLGPAGFENFHQCSGFVGHGFMMAPAVAERYADWLAGRGKDEIFE
HHHHCEECCCCCCCCEECCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCHHHHHH
RFTLGRFESGAVAREDFIIG
HHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]