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The map label for this gene is truD2 [H]

Identifier: 220916569

GI number: 220916569

Start: 1636199

End: 1637566

Strand: Reverse

Name: truD2 [H]

Synonym: A2cp1_1463

Alternate gene names: 220916569

Gene position: 1637566-1636199 (Counterclockwise)

Preceding gene: 220916571

Following gene: 220916562

Centisome position: 32.56

GC content: 73.03

Gene sequence:

>1368_bases
ATGAGGCTCAAGCAGCGACCGGAGGACTTCCAGGTGACGGAGTCCTGGAAGTTCGACGAGGACCCCCGCGGCGCCTGGTT
CGTCTACCTGATGGACAAGCAGAAGCTGTCGACCTTCGAGGCGGTCGACCGCATCTGCACGCGCTTCAAGATCCCGCGGG
CGTCGGTGAGCTACTGCGGGCTGAAGGACAAGCAGGGGCGCACCACCCAGCTCGTCGCCCTCGAGCGCCGCGAGATCGAG
CTGCAGGACACCGACCTGCGCCTCAAGCCGCTGGGCCGGAGCCGCACGCGGCTGTCCGCCGCGAACACCACCTCCAACCG
CTTCGCGGTGACGGTGCGCGACCTCGGCGAGGACGACGTGGCGCGCCTGCCCGCGTCGGTGGCCGAGGTGCGCCGGCTCG
GGGTGGTGAACTACTTCGACTCGCAGCGCTTCGGCTCGCTGAAGCACGGCCAGGGCTTCATCGTGAAGGACCTGATGCGC
GGCGACTTCGAGATCGCGCTGCGCAACGTCCTGGCCCGCCCGAGCGAGCTGGACCAGTCCGGCGACGCGAAGGTGAAGGC
GTTCTGGAAGGAGCACTGGGGCGAGTGGGACCGGCGCAACCCGAACCCGGGCGCCGAGCGCTACCAGGCGGTGGTGAAGT
GGCTGCGCGATCACCCGGAGGACTACCGGGGCGCGCTGCTCCGCACCGAGCCGCGCTGGCGCGGGCTGCAGGTGTTCGCC
TACCAGAGCTGGCTCTGGAACGAGGGCGTGAAGCAGTACCTGCGCGAGGTGGTGGGGATCCAGCGGCTCGTGTCCCTGCG
CTACCAGGCCGGGTCGCTCCTGTTCCCGCGCGAGCTGGACGCGGCGCTGGTGCGGCTGCTCTCGTCGAAGACCTTCCCGC
TGCTCGCGCCGTCCACCCGCTTCGACGACCCGGCGGTGGAGCGCGCCGCGCTGTCGGTGCTCGGCCGCGAGGACATGGGG
CTCGCGGACCTGGCGGTGCCGGGGACGCCGGAGATCCACTTCGACCCCGAGGAGCGGCCGTTGTTCTCGTTCCCGGGCCG
CCTCGCGGTGGGCGAGGCGCGCCCGGACGAGCTGAACCGCGACCGGTTCCGGGTGAACGTCGCCTTCACGCTGCCGCCCG
GCGCGTACGCGACGCTGGTGGTGAAGCGGCTGTTCCACTGGACGCTCGAGCCGCGCCGCGCGCGCGAGGGCGTCCGGTCC
CGGGCGCCCGCGCCGTCCACGCGGGGCGCGCCGGAGGCGGAACAGCCGGTCGAGGCGCCGCGGGCGCCCGCCGCGCCGAA
GGGCTTCCTGGCCCGGAAGCGCGCCGAGAAGGCGGCGCGCGCGGAGCGTCGCGCGGCGGGCAAGGCGACGGCGAAGCCGA
GGCGCTGA

Upstream 100 bases:

>100_bases
CGGTTTCGATACACTCGTTCGGGCTGGCGCGCCAGCGCCGCAGCGCGCGCCCCTTCCGTTCGACCCCCACGCCGCGGCGC
GCGCGTGGTACGGAGCGGCC

Downstream 100 bases:

>100_bases
GCCGCGGGGCGAGCGGGGCCGAGGTCCTCAGCACGGCCGCGGGTCGGCCCACTCCCACACCAGCGTGCCCTCGCGCGCCC
GGTCCTGGAGCAGCTCGGCG

Product: tRNA pseudouridine synthase D TruD

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D 2; tRNA-uridine isomerase D 2 [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MRLKQRPEDFQVTESWKFDEDPRGAWFVYLMDKQKLSTFEAVDRICTRFKIPRASVSYCGLKDKQGRTTQLVALERREIE
LQDTDLRLKPLGRSRTRLSAANTTSNRFAVTVRDLGEDDVARLPASVAEVRRLGVVNYFDSQRFGSLKHGQGFIVKDLMR
GDFEIALRNVLARPSELDQSGDAKVKAFWKEHWGEWDRRNPNPGAERYQAVVKWLRDHPEDYRGALLRTEPRWRGLQVFA
YQSWLWNEGVKQYLREVVGIQRLVSLRYQAGSLLFPRELDAALVRLLSSKTFPLLAPSTRFDDPAVERAALSVLGREDMG
LADLAVPGTPEIHFDPEERPLFSFPGRLAVGEARPDELNRDRFRVNVAFTLPPGAYATLVVKRLFHWTLEPRRAREGVRS
RAPAPSTRGAPEAEQPVEAPRAPAAPKGFLARKRAEKAARAERRAAGKATAKPRR

Sequences:

>Translated_455_residues
MRLKQRPEDFQVTESWKFDEDPRGAWFVYLMDKQKLSTFEAVDRICTRFKIPRASVSYCGLKDKQGRTTQLVALERREIE
LQDTDLRLKPLGRSRTRLSAANTTSNRFAVTVRDLGEDDVARLPASVAEVRRLGVVNYFDSQRFGSLKHGQGFIVKDLMR
GDFEIALRNVLARPSELDQSGDAKVKAFWKEHWGEWDRRNPNPGAERYQAVVKWLRDHPEDYRGALLRTEPRWRGLQVFA
YQSWLWNEGVKQYLREVVGIQRLVSLRYQAGSLLFPRELDAALVRLLSSKTFPLLAPSTRFDDPAVERAALSVLGREDMG
LADLAVPGTPEIHFDPEERPLFSFPGRLAVGEARPDELNRDRFRVNVAFTLPPGAYATLVVKRLFHWTLEPRRAREGVRS
RAPAPSTRGAPEAEQPVEAPRAPAAPKGFLARKRAEKAARAERRAAGKATAKPRR
>Mature_455_residues
MRLKQRPEDFQVTESWKFDEDPRGAWFVYLMDKQKLSTFEAVDRICTRFKIPRASVSYCGLKDKQGRTTQLVALERREIE
LQDTDLRLKPLGRSRTRLSAANTTSNRFAVTVRDLGEDDVARLPASVAEVRRLGVVNYFDSQRFGSLKHGQGFIVKDLMR
GDFEIALRNVLARPSELDQSGDAKVKAFWKEHWGEWDRRNPNPGAERYQAVVKWLRDHPEDYRGALLRTEPRWRGLQVFA
YQSWLWNEGVKQYLREVVGIQRLVSLRYQAGSLLFPRELDAALVRLLSSKTFPLLAPSTRFDDPAVERAALSVLGREDMG
LADLAVPGTPEIHFDPEERPLFSFPGRLAVGEARPDELNRDRFRVNVAFTLPPGAYATLVVKRLFHWTLEPRRAREGVRS
RAPAPSTRGAPEAEQPVEAPRAPAAPKGFLARKRAEKAARAERRAAGKATAKPRR

Specific function: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 51865; Mature: 51865

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKQRPEDFQVTESWKFDEDPRGAWFVYLMDKQKLSTFEAVDRICTRFKIPRASVSYCG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHCC
LKDKQGRTTQLVALERREIELQDTDLRLKPLGRSRTRLSAANTTSNRFAVTVRDLGEDDV
CCCCCCCCEEEEEEHHHEEEEECCCEEEECCCCCHHHEEECCCCCCEEEEEEECCCCHHH
ARLPASVAEVRRLGVVNYFDSQRFGSLKHGQGFIVKDLMRGDFEIALRNVLARPSELDQS
HHCCHHHHHHHHHCCHHHHCCHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCHHCCCC
GDAKVKAFWKEHWGEWDRRNPNPGAERYQAVVKWLRDHPEDYRGALLRTEPRWRGLQVFA
CCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCEEEEE
YQSWLWNEGVKQYLREVVGIQRLVSLRYQAGSLLFPRELDAALVRLLSSKTFPLLAPSTR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCC
FDDPAVERAALSVLGREDMGLADLAVPGTPEIHFDPEERPLFSFPGRLAVGEARPDELNR
CCCHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCEEECCCCCCCCCC
DRFRVNVAFTLPPGAYATLVVKRLFHWTLEPRRAREGVRSRAPAPSTRGAPEAEQPVEAP
CEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RAPAAPKGFLARKRAEKAARAERRAAGKATAKPRR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRLKQRPEDFQVTESWKFDEDPRGAWFVYLMDKQKLSTFEAVDRICTRFKIPRASVSYCG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHCC
LKDKQGRTTQLVALERREIELQDTDLRLKPLGRSRTRLSAANTTSNRFAVTVRDLGEDDV
CCCCCCCCEEEEEEHHHEEEEECCCEEEECCCCCHHHEEECCCCCCEEEEEEECCCCHHH
ARLPASVAEVRRLGVVNYFDSQRFGSLKHGQGFIVKDLMRGDFEIALRNVLARPSELDQS
HHCCHHHHHHHHHCCHHHHCCHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCHHCCCC
GDAKVKAFWKEHWGEWDRRNPNPGAERYQAVVKWLRDHPEDYRGALLRTEPRWRGLQVFA
CCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCEEEEE
YQSWLWNEGVKQYLREVVGIQRLVSLRYQAGSLLFPRELDAALVRLLSSKTFPLLAPSTR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCC
FDDPAVERAALSVLGREDMGLADLAVPGTPEIHFDPEERPLFSFPGRLAVGEARPDELNR
CCCHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCEEECCCCCCCCCC
DRFRVNVAFTLPPGAYATLVVKRLFHWTLEPRRAREGVRSRAPAPSTRGAPEAEQPVEAP
CEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RAPAAPKGFLARKRAEKAARAERRAAGKATAKPRR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]