Click here to switch to the map view.

The map label for this gene is nuoB1

Identifier: 220916483

GI number: 220916483

Start: 1542986

End: 1543507

Strand: Reverse

Name: nuoB1

Synonym: A2cp1_1377

Alternate gene names: 220916483

Gene position: 1543507-1542986 (Counterclockwise)

Preceding gene: 220916484

Following gene: 220916482

Centisome position: 30.69

GC content: 70.5

Gene sequence:

>522_bases
ATGGCGGCACGCATGGACCCGGGGATCGGCGGCGACGTCACGCTGCTCCACACGAGCCAGCTGGACAACCTCATCAACCT
CGCGCGCGCGAGCTCGCTCTACTACCTGACGTTCGGCCTGGCCTGCTGCGGCATCGAGCTGATGCAGACCGGCGGCCCGC
GCGCCGACGTGATGCGCTTCGGCGCGATCCCCCGCGCCTCCCCGCGCCAGGCCGACTTCATGATCGTGGCCGGCACGCTC
ACCTACAAGATGGCCGAGCGCGCCCGCCTGCTCTACGACCAGATGCCCGAGCCGAAGTACGTCATCTCGATGGGCTCCTG
CTCGAACTGCGGCGGCCTCTTCCAGCTCGGCTACTCGGTCTGCAAGGGCGTCGACAAGGTCATCCCGGTGGACGTCTACG
TCCCGGGCTGCCCGCCGCGGCCGGAGGCGCTCACCGAGGGCCTCCTCCGGCTCCAGGAGATCGTCCGGAGCGAGCCCTGG
TCCACCAAGCGTCGCCCGGCAGCGCAGGCGGAGGGTGCCTAG

Upstream 100 bases:

>100_bases
CCGCGCCGCGCGGCCTGACGGAACAACTCGGGCGGCACCGGCGGTTCATCAACTGATCGCGGTCAAACGCAGGACGCGCA
AGGCAGGAGGCGGTTCGCAC

Downstream 100 bases:

>100_bases
CGGCCTCCCTTCCACCACTCGTAGCTCGCTGACCGGCAGTTTCAGGACGGGGCGGGGCGGAACGCTCGGATGGGGCGTAC
CGCTTCGCCCTGTACCGTAG

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B 1; NDH-1 subunit B 1

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAARMDPGIGGDVTLLHTSQLDNLINLARASSLYYLTFGLACCGIELMQTGGPRADVMRFGAIPRASPRQADFMIVAGTL
TYKMAERARLLYDQMPEPKYVISMGSCSNCGGLFQLGYSVCKGVDKVIPVDVYVPGCPPRPEALTEGLLRLQEIVRSEPW
STKRRPAAQAEGA

Sequences:

>Translated_173_residues
MAARMDPGIGGDVTLLHTSQLDNLINLARASSLYYLTFGLACCGIELMQTGGPRADVMRFGAIPRASPRQADFMIVAGTL
TYKMAERARLLYDQMPEPKYVISMGSCSNCGGLFQLGYSVCKGVDKVIPVDVYVPGCPPRPEALTEGLLRLQEIVRSEPW
STKRRPAAQAEGA
>Mature_172_residues
AARMDPGIGGDVTLLHTSQLDNLINLARASSLYYLTFGLACCGIELMQTGGPRADVMRFGAIPRASPRQADFMIVAGTLT
YKMAERARLLYDQMPEPKYVISMGSCSNCGGLFQLGYSVCKGVDKVIPVDVYVPGCPPRPEALTEGLLRLQEIVRSEPWS
TKRRPAAQAEGA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family

Homologues:

Organism=Homo sapiens, GI187281616, Length=141, Percent_Identity=58.1560283687943, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1788624, Length=154, Percent_Identity=51.9480519480519, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1789074, Length=156, Percent_Identity=37.8205128205128, Blast_Score=97, Evalue=4e-22,
Organism=Escherichia coli, GI1788834, Length=126, Percent_Identity=36.5079365079365, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509685, Length=140, Percent_Identity=56.4285714285714, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI18859983, Length=138, Percent_Identity=58.695652173913, Blast_Score=180, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24642371, Length=138, Percent_Identity=58.695652173913, Blast_Score=180, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24651058, Length=138, Percent_Identity=58.695652173913, Blast_Score=179, Evalue=1e-45,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOB1_ANASK (B4UIA4)

Other databases:

- EMBL:   CP001131
- RefSeq:   YP_002133638.1
- ProteinModelPortal:   B4UIA4
- SMR:   B4UIA4
- GeneID:   6786593
- GenomeReviews:   CP001131_GR
- KEGG:   ank:AnaeK_1276
- HOGENOM:   HBG553221
- OMA:   NYDLERF
- ProtClustDB:   PRK14818
- GO:   GO:0006810
- HAMAP:   MF_01356
- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406
- PANTHER:   PTHR11995:SF2
- PANTHER:   PTHR11995
- TIGRFAMs:   TIGR01957

Pfam domain/function: PF01058 Oxidored_q6

EC number: =1.6.99.5

Molecular weight: Translated: 18758; Mature: 18627

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARMDPGIGGDVTLLHTSQLDNLINLARASSLYYLTFGLACCGIELMQTGGPRADVMRF
CCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GAIPRASPRQADFMIVAGTLTYKMAERARLLYDQMPEPKYVISMGSCSNCGGLFQLGYSV
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHH
CKGVDKVIPVDVYVPGCPPRPEALTEGLLRLQEIVRSEPWSTKRRPAAQAEGA
HCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AARMDPGIGGDVTLLHTSQLDNLINLARASSLYYLTFGLACCGIELMQTGGPRADVMRF
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GAIPRASPRQADFMIVAGTLTYKMAERARLLYDQMPEPKYVISMGSCSNCGGLFQLGYSV
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHH
CKGVDKVIPVDVYVPGCPPRPEALTEGLLRLQEIVRSEPWSTKRRPAAQAEGA
HCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA