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The map label for this gene is nuoC [H]

Identifier: 220916482

GI number: 220916482

Start: 1542284

End: 1542874

Strand: Reverse

Name: nuoC [H]

Synonym: A2cp1_1376

Alternate gene names: 220916482

Gene position: 1542874-1542284 (Counterclockwise)

Preceding gene: 220916483

Following gene: 220916481

Centisome position: 30.68

GC content: 71.4

Gene sequence:

>591_bases
ATGACGACTCATGAAATCCACGAGCGGCTGAAGGCGCGGTTCGGAGACGACGTCGGCCCGCTGTCCGAGCCGAAGATCGA
CGCGTTCTGCGTGGTGAAGGCGGAGCGGATCGTCGAGGTCTCCCGCTTCCTCGCCACCGAGCCCGGCCTCGAGATGGACT
TCCTCGAGGACCTGACCGCGGTGGACTGGCCGAAGCGGAACGTGATCGAGGTCGTCTACCACCTGCTCTCGTACCGGCAC
CGCCACGCGATCGTGCTGAAGGTCGAGGCGGACCGCGCCGCGCCGGTCGTCCCGACCGTCGAGGCCGTCTGGAAGACCGC
GAACTGGTTCGAGCGCGAGGTCTACGACCTGTTCGGCGTGAGCTTCCCCGGCCACCCGGACCTGCGCCGGCTGATGCTGC
CGGACGACTGGGTGGGCCACCCGCTCCGCAAGGACTACCAGGAGGCGGGCGGCTGGCACGGCATCTCCAACGTCCGCGAG
AACCCGCTCGTCGAGCTGAAGCGGCTCGACGACCAGCGCCGCGCCGAGGCCGCCGCCAGGGCGGCGCCGCCGGCCGCGCC
CGACGCCGCCGCGGCCGCCCCCAAGGCGTAG

Upstream 100 bases:

>100_bases
CCACCACTCGTAGCTCGCTGACCGGCAGTTTCAGGACGGGGCGGGGCGGAACGCTCGGATGGGGCGTACCGCTTCGCCCT
GTACCGTAGAAGAGGGACGA

Downstream 100 bases:

>100_bases
GGAGACGACATGGAAAAGCTCATCCTCCGCCGCGTGGACCGCCAGAACGAGGAGATGATCCTCAACTTCGGCCCGCAGCA
CCCGTCCACCCACGGCGTCA

Product: NADH (or F420H2) dehydrogenase, subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTTHEIHERLKARFGDDVGPLSEPKIDAFCVVKAERIVEVSRFLATEPGLEMDFLEDLTAVDWPKRNVIEVVYHLLSYRH
RHAIVLKVEADRAAPVVPTVEAVWKTANWFEREVYDLFGVSFPGHPDLRRLMLPDDWVGHPLRKDYQEAGGWHGISNVRE
NPLVELKRLDDQRRAEAAARAAPPAAPDAAAAAPKA

Sequences:

>Translated_196_residues
MTTHEIHERLKARFGDDVGPLSEPKIDAFCVVKAERIVEVSRFLATEPGLEMDFLEDLTAVDWPKRNVIEVVYHLLSYRH
RHAIVLKVEADRAAPVVPTVEAVWKTANWFEREVYDLFGVSFPGHPDLRRLMLPDDWVGHPLRKDYQEAGGWHGISNVRE
NPLVELKRLDDQRRAEAAARAAPPAAPDAAAAAPKA
>Mature_195_residues
TTHEIHERLKARFGDDVGPLSEPKIDAFCVVKAERIVEVSRFLATEPGLEMDFLEDLTAVDWPKRNVIEVVYHLLSYRHR
HAIVLKVEADRAAPVVPTVEAVWKTANWFEREVYDLFGVSFPGHPDLRRLMLPDDWVGHPLRKDYQEAGGWHGISNVREN
PLVELKRLDDQRRAEAAARAAPPAAPDAAAAAPKA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=154, Percent_Identity=37.6623376623377, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI145693162, Length=146, Percent_Identity=40.4109589041096, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1789076, Length=119, Percent_Identity=39.4957983193277, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32563621, Length=134, Percent_Identity=40.2985074626866, Blast_Score=90, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=134, Percent_Identity=40.2985074626866, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24656494, Length=145, Percent_Identity=36.551724137931, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22114; Mature: 21983

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHEIHERLKARFGDDVGPLSEPKIDAFCVVKAERIVEVSRFLATEPGLEMDFLEDLTA
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VDWPKRNVIEVVYHLLSYRHRHAIVLKVEADRAAPVVPTVEAVWKTANWFEREVYDLFGV
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
SFPGHPDLRRLMLPDDWVGHPLRKDYQEAGGWHGISNVRENPLVELKRLDDQRRAEAAAR
CCCCCCCHHEECCCCCCCCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHCCHHHHHHHHHH
AAPPAAPDAAAAAPKA
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTHEIHERLKARFGDDVGPLSEPKIDAFCVVKAERIVEVSRFLATEPGLEMDFLEDLTA
CHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VDWPKRNVIEVVYHLLSYRHRHAIVLKVEADRAAPVVPTVEAVWKTANWFEREVYDLFGV
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
SFPGHPDLRRLMLPDDWVGHPLRKDYQEAGGWHGISNVRENPLVELKRLDDQRRAEAAAR
CCCCCCCHHEECCCCCCCCCHHHHHHHHCCCCCCHHHCCCCHHHHHHHCCHHHHHHHHHH
AAPPAAPDAAAAAPKA
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA