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The map label for this gene is speB1 [H]

Identifier: 220916471

GI number: 220916471

Start: 1529202

End: 1530227

Strand: Reverse

Name: speB1 [H]

Synonym: A2cp1_1365

Alternate gene names: 220916471

Gene position: 1530227-1529202 (Counterclockwise)

Preceding gene: 220916472

Following gene: 220916470

Centisome position: 30.43

GC content: 76.32

Gene sequence:

>1026_bases
ATGACCTTCGATCCTTCCGCCGCCGCGCAGCCCGGCTCCGGCGTGTTCGGCCTCCCCCACTCCGAGCGCGACGCCGGCGT
GGTGCTCGTCCCGGTGCCGTTCGAGGCGACCACCTCCTACGGCGGCGGCACCTCGCGCGGCCCGGAGGCGATCCTCGACG
CGAGCCGGCAGGTGGACCTGTTCGACGTGGAGACCGGCCGCCCGTACGAGGCCGGCATCCACATGCTGCCCGTCCCCGAG
GAGATCGCGCGGCTCGACCGCGAGGCGCGCGCCGCCGCCGAGCCGGTCATCGCCGCCGGCGGGCTCGTGCCCGGCCGCCA
GGACCTGGCCCGGGCGGTCGCCGAGGTGGACGAGGCCTGCGGGCGCGTGAACGCCTGGGTCGAGGAGCGCGTCGCCGGCC
TGCTCGCCCGCGGCAAGACCGTCGGCCTGGTGGGCGGCGACCACTCCACCGCGCTCGGCGCGATCGCCGCGCACGCGCGC
CGCCACCCGGGCATGGGTCTGCTGCACGTGGACGCCCACGCCGACCTGCGGGTCGCGTTCGAGGGGTTCACGTACAGCCA
CGCGTCGGTGATCTACAACGCGGCCGAGCGGCTCCCGGAGCTGTCGCGGATCGTCCAGGTCGGCCTGCGCGACCTCTCCG
AGGAGGAGCACGCCTACGCGGCCGCGTCGGGGGGCCGCGTCGTGCAGCACCACGACGCCCCGCTGGCGCGCGCGCGCTTC
GAGGGCGAGCCCTGGGCGGCGCAGGTCCGGCGCATCGTCGAGCCGCTGCCGCGCGAGGTGTACGTCAGCTTCGACGTGGA
CGGGCTCGACCCCACGCTCTGCCCGCACACCGGCACGCCGGTGCCGGGCGGCCTCTCGTTCCAGGAGGCCGCGTACCTGA
TCGGCGCCGTGGTGCGCAGCGGCAGGCGCATCGTCGGCTTCGACCTGGTGGAGGTGTCGCCCGGGCCCGACGGCGGCGAC
TGGGACGGCAACGTGGGCGCCCGCCTGCTCTACAAGCTGATCGGCTGGGCGCTGGCCGGGCGCTGA

Upstream 100 bases:

>100_bases
CTCGCGCGAGGTCCCCGCGGGCGCGCCTGACGGCGCGCGGTCAGCGACGCGATCGGATCCTCACGGGCTGCGCCCCGTCC
GGCCGCGTTAGACTCCGGCC

Downstream 100 bases:

>100_bases
GCGGCGCCGCGTCCCGGCGCGCGCCCGGCACGTCGTTGCCGCGGCGCCGTCCGGCCATACCGTTCAGGGTGTGAAGCCGC
CGCTGCGCCTCGACGAGCCG

Product: Arginase/agmatinase/formiminoglutamase

Products: NA

Alternate protein names: Agmatine ureohydrolase 1; AUH 1 [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTFDPSAAAQPGSGVFGLPHSERDAGVVLVPVPFEATTSYGGGTSRGPEAILDASRQVDLFDVETGRPYEAGIHMLPVPE
EIARLDREARAAAEPVIAAGGLVPGRQDLARAVAEVDEACGRVNAWVEERVAGLLARGKTVGLVGGDHSTALGAIAAHAR
RHPGMGLLHVDAHADLRVAFEGFTYSHASVIYNAAERLPELSRIVQVGLRDLSEEEHAYAAASGGRVVQHHDAPLARARF
EGEPWAAQVRRIVEPLPREVYVSFDVDGLDPTLCPHTGTPVPGGLSFQEAAYLIGAVVRSGRRIVGFDLVEVSPGPDGGD
WDGNVGARLLYKLIGWALAGR

Sequences:

>Translated_341_residues
MTFDPSAAAQPGSGVFGLPHSERDAGVVLVPVPFEATTSYGGGTSRGPEAILDASRQVDLFDVETGRPYEAGIHMLPVPE
EIARLDREARAAAEPVIAAGGLVPGRQDLARAVAEVDEACGRVNAWVEERVAGLLARGKTVGLVGGDHSTALGAIAAHAR
RHPGMGLLHVDAHADLRVAFEGFTYSHASVIYNAAERLPELSRIVQVGLRDLSEEEHAYAAASGGRVVQHHDAPLARARF
EGEPWAAQVRRIVEPLPREVYVSFDVDGLDPTLCPHTGTPVPGGLSFQEAAYLIGAVVRSGRRIVGFDLVEVSPGPDGGD
WDGNVGARLLYKLIGWALAGR
>Mature_340_residues
TFDPSAAAQPGSGVFGLPHSERDAGVVLVPVPFEATTSYGGGTSRGPEAILDASRQVDLFDVETGRPYEAGIHMLPVPEE
IARLDREARAAAEPVIAAGGLVPGRQDLARAVAEVDEACGRVNAWVEERVAGLLARGKTVGLVGGDHSTALGAIAAHARR
HPGMGLLHVDAHADLRVAFEGFTYSHASVIYNAAERLPELSRIVQVGLRDLSEEEHAYAAASGGRVVQHHDAPLARARFE
GEPWAAQVRRIVEPLPREVYVSFDVDGLDPTLCPHTGTPVPGGLSFQEAAYLIGAVVRSGRRIVGFDLVEVSPGPDGGDW
DGNVGARLLYKLIGWALAGR

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=214, Percent_Identity=29.4392523364486, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI37537722, Length=230, Percent_Identity=31.7391304347826, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4502215, Length=255, Percent_Identity=27.0588235294118, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1789306, Length=297, Percent_Identity=31.986531986532, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325146, Length=321, Percent_Identity=25.2336448598131, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24638886, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 36039; Mature: 35908

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDPSAAAQPGSGVFGLPHSERDAGVVLVPVPFEATTSYGGGTSRGPEAILDASRQVDL
CCCCCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEE
FDVETGRPYEAGIHMLPVPEEIARLDREARAAAEPVIAAGGLVPGRQDLARAVAEVDEAC
EECCCCCCHHHCEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHH
GRVNAWVEERVAGLLARGKTVGLVGGDHSTALGAIAAHARRHPGMGLLHVDAHADLRVAF
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEE
EGFTYSHASVIYNAAERLPELSRIVQVGLRDLSEEEHAYAAASGGRVVQHHDAPLARARF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCEEEECCCCHHHHHC
EGEPWAAQVRRIVEPLPREVYVSFDVDGLDPTLCPHTGTPVPGGLSFQEAAYLIGAVVRS
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GRRIVGFDLVEVSPGPDGGDWDGNVGARLLYKLIGWALAGR
CCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFDPSAAAQPGSGVFGLPHSERDAGVVLVPVPFEATTSYGGGTSRGPEAILDASRQVDL
CCCCCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEE
FDVETGRPYEAGIHMLPVPEEIARLDREARAAAEPVIAAGGLVPGRQDLARAVAEVDEAC
EECCCCCCHHHCEEECCCCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHH
GRVNAWVEERVAGLLARGKTVGLVGGDHSTALGAIAAHARRHPGMGLLHVDAHADLRVAF
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEE
EGFTYSHASVIYNAAERLPELSRIVQVGLRDLSEEEHAYAAASGGRVVQHHDAPLARARF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCEEEECCCCHHHHHC
EGEPWAAQVRRIVEPLPREVYVSFDVDGLDPTLCPHTGTPVPGGLSFQEAAYLIGAVVRS
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GRRIVGFDLVEVSPGPDGGDWDGNVGARLLYKLIGWALAGR
CCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]