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The map label for this gene is cheW [H]

Identifier: 220915746

GI number: 220915746

Start: 703245

End: 703829

Strand: Reverse

Name: cheW [H]

Synonym: A2cp1_0627

Alternate gene names: 220915746

Gene position: 703829-703245 (Counterclockwise)

Preceding gene: 220915747

Following gene: 220915745

Centisome position: 13.99

GC content: 73.16

Gene sequence:

>585_bases
ATGGCCGAGAGCACCGAGAGCGCGCAGCGCGCACAGTACCTGTCCTTCTCGCTGGGGGGCGCCGAGTACGGCGTCGGCAT
CCTCAAGGTGAAGGAGATCCTGCAGTACGAGGCGATCACGCGCGTGCCTTCCACGCCGCGCTCCGTCCGCGGGGTCATCA
ACCTGCGAGGCGCGGTGGTCCCGGTGATCGACCTGGGCGTGAAGTTCGGCCTGGCCGAGACCGAGGTGACCCGCCTCACC
TGCATCCTGATCGTCGAGGCGCTGCTCGAGGGCCAGCCCACGGTCGTGGGCGTCATGGCCGACGCGGTCCGCGAGGTGAT
CGAGCTCGGGTTCGACGACGTCGAGCCGCCCCCGTCCTTCGGCACCCAGGTCCGCGTGGACTTCCTGCTCGGCATGGGCA
AGGTCGGCAAGCGCTTCGTGCTGCTGCTCGACCTCGACCGGGTGATCTCCGCCGACGAGAAGGAGTTCGCCGAGGCGGTG
CGCGACGGGCTGCCCGAGGCCGAGGCGCCCGCCGCCGAGGGCGCCGCCGGCGACGCCGCCGCCGCCGCGCCCGAGCCCGC
CGCGGAGGCGCCGCCCGCCCCGTGA

Upstream 100 bases:

>100_bases
TGGCCCTGATCCTGGACGTGGCGGGCATCCTGCGCGAGACGCTCCGCCGGGCGGCGGCGCAGGCGGCCGCCTGAGGCATC
GCGAACCCGAGGGAGGAACC

Downstream 100 bases:

>100_bases
GCCGCGCCGCCGAGGAGGGCGCGCCCCGCCGCGCCGCGCTGGTCGAACCGCGCCCGCTCGCCACGGTGAGCGACCGCGAC
TTCCTGCGCTTCCAGGCGCT

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAESTESAQRAQYLSFSLGGAEYGVGILKVKEILQYEAITRVPSTPRSVRGVINLRGAVVPVIDLGVKFGLAETEVTRLT
CILIVEALLEGQPTVVGVMADAVREVIELGFDDVEPPPSFGTQVRVDFLLGMGKVGKRFVLLLDLDRVISADEKEFAEAV
RDGLPEAEAPAAEGAAGDAAAAAPEPAAEAPPAP

Sequences:

>Translated_194_residues
MAESTESAQRAQYLSFSLGGAEYGVGILKVKEILQYEAITRVPSTPRSVRGVINLRGAVVPVIDLGVKFGLAETEVTRLT
CILIVEALLEGQPTVVGVMADAVREVIELGFDDVEPPPSFGTQVRVDFLLGMGKVGKRFVLLLDLDRVISADEKEFAEAV
RDGLPEAEAPAAEGAAGDAAAAAPEPAAEAPPAP
>Mature_193_residues
AESTESAQRAQYLSFSLGGAEYGVGILKVKEILQYEAITRVPSTPRSVRGVINLRGAVVPVIDLGVKFGLAETEVTRLTC
ILIVEALLEGQPTVVGVMADAVREVIELGFDDVEPPPSFGTQVRVDFLLGMGKVGKRFVLLLDLDRVISADEKEFAEAVR
DGLPEAEAPAAEGAAGDAAAAAPEPAAEAPPAP

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=148, Percent_Identity=33.7837837837838, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 20341; Mature: 20209

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESTESAQRAQYLSFSLGGAEYGVGILKVKEILQYEAITRVPSTPRSVRGVINLRGAVV
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHH
PVIDLGVKFGLAETEVTRLTCILIVEALLEGQPTVVGVMADAVREVIELGFDDVEPPPSF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCC
GTQVRVDFLLGMGKVGKRFVLLLDLDRVISADEKEFAEAVRDGLPEAEAPAAEGAAGDAA
CCCEEHHHHHCCCHHCCCEEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
AAAPEPAAEAPPAP
CCCCCCCCCCCCCC
>Mature Secondary Structure 
AESTESAQRAQYLSFSLGGAEYGVGILKVKEILQYEAITRVPSTPRSVRGVINLRGAVV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHH
PVIDLGVKFGLAETEVTRLTCILIVEALLEGQPTVVGVMADAVREVIELGFDDVEPPPSF
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCC
GTQVRVDFLLGMGKVGKRFVLLLDLDRVISADEKEFAEAVRDGLPEAEAPAAEGAAGDAA
CCCEEHHHHHCCCHHCCCEEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
AAAPEPAAEAPPAP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]