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The map label for this gene is cheA [H]

Identifier: 220915747

GI number: 220915747

Start: 703856

End: 705517

Strand: Reverse

Name: cheA [H]

Synonym: A2cp1_0628

Alternate gene names: 220915747

Gene position: 705517-703856 (Counterclockwise)

Preceding gene: 220915748

Following gene: 220915746

Centisome position: 14.03

GC content: 75.15

Gene sequence:

>1662_bases
ATGGACGAGCTCGAGATCGATCGCGAGGCGCTGCTCGCCACGTTCCTGGCGGAGGCGGACGAGACGTTCGCGCACATGGA
GCAGCAGCTCCTCGCGCTCGAGCGCACGCCGGAGGACGACGAGCTCCTGAACGCGCTGTTCCGCGACGTGCACACGCTGA
AGGGCGCCGCGTCGCTGGTGTCGTTCGACGGCGCGCGCGACGTGGCGCACGACCTCGAGGACGTGCTGGAGCGGCTCCGC
CAGAAGACGCTCGCGGTCACCGACGCGCTGGTGACGCTGCTGCTCCAGTCGGTGGACGTGCTCCGCCGGGCCGTGGCCGA
GGCCGAGGCCGGGGCCGGTGGGGGCGGCGCCTCGGACGCGGTCCTGGCGTTCCGCGCCAGGCTGGCCGAGGCGGCCCGGG
CGGCGGTGGCCGAGCGCGCCGCGCCCTCGGGCGCCGCCGAGGCGCCGGACGCGCACGAGCCGCACGCGCCGCACGCAGCC
GCCGCGCGCACGCTCCGCGTCGACGTGGGCAAGCTCGACCGCATGCTCAACCTGTCGGGCGAGATCGCCATCGCGCGCGG
GCGCCTGGGCGAGATGCTGGAGCGGCGTGGCGGGGTGTCGGCGGAGGACGCGCTCGACGCGCACCGCGAGGCGGACCGGC
TCTACCTCGACCTGCAGGAGCTGATCATGAAGGCCCGCATGGTGCCCATCGGGCCGACGTTCCACCAGCACGTGCGCACG
CTGCGCGACCTCGCCTCGAACCTGGGCAAGCAGGCCCGGCTGGTGATGGAGGGCGAGGACGTCGAGGTGGACACCGCGGT
CATCGAGCACATCCGCGACCCGCTGCTGCACATGGTCCGCAACGCGCTCGACCACGGCATCGAGCGGCCCGACGAGCGGC
GCGCCGCGGGCAAGCCGCCGGTGGGCACGCTCACGCTGCGCGCGTTCCACGACGCGGGCAGCATGGTGGTGCAGGTGCTG
GACGACGGGCGCGGCCTGGACGTGCGGCGCATCGCGCAGCAGGCGGTGGCGCGCGGGCTCGCCTCCGATCCCGCCCGCAT
CGGCCCCGAGGACGCGGCCGGCCTGATCTTCGAGCCGGGCCTGTCCACCGCGGACGCGGTCACCGAGCTGTCCGGCCGCG
GCGTGGGCATGGACGTGGTCCGGCGCAACATCGAGGCGCTGCGCGGCTCGGTGTCGGTGGAGAGCGAGCCGGGGCACGGC
ACCGCCATCACCCTGCGCGTCCCGCTCACCCTCGCCATCATCCAGGGCTTCAAGGTGGGCGTGGGCGGCGAGACGTACAT
CCTCCCGCTCGACGCGGTCTCCGAGTGCCTGGAGCTCCCGCCGGAGGAGACGCGGGCCGGCGCGCCCTGGGGCGTCATCA
ACGTGCGCGGGAAGCCGCTCCCGTACCTGCGGCTCCGCGACCACTTCAAGGTGGCCGGCGCCGCGCCGCAGCGCGAGAAC
GTGGTGGTGGTGCAGCACGGCGCCCAGGTGGCGGGCGTGGCCGTGGACGTGCTGCACGGCGAGAGCTCGACGGTGATCAA
GCCGCTGGGCGGGCTGGTGGGCGCCGTGGCCGGCGTCTCGGGATCGTCGATCCTGGGCAACGGCCGGGTGGCCCTGATCC
TGGACGTGGCGGGCATCCTGCGCGAGACGCTCCGCCGGGCGGCGGCGCAGGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
CCCGGTGCTCGACCGCGACGTGGGCGGCGCGCGGGGGCGCAAGCTCATCTTCCACGTGGACGACGGCGCCGCCTGGGTGC
GGCAGCTCTAGGGAGCGGTG

Downstream 100 bases:

>100_bases
GGCATCGCGAACCCGAGGGAGGAACCATGGCCGAGAGCACCGAGAGCGCGCAGCGCGCACAGTACCTGTCCTTCTCGCTG
GGGGGCGCCGAGTACGGCGT

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MDELEIDREALLATFLAEADETFAHMEQQLLALERTPEDDELLNALFRDVHTLKGAASLVSFDGARDVAHDLEDVLERLR
QKTLAVTDALVTLLLQSVDVLRRAVAEAEAGAGGGGASDAVLAFRARLAEAARAAVAERAAPSGAAEAPDAHEPHAPHAA
AARTLRVDVGKLDRMLNLSGEIAIARGRLGEMLERRGGVSAEDALDAHREADRLYLDLQELIMKARMVPIGPTFHQHVRT
LRDLASNLGKQARLVMEGEDVEVDTAVIEHIRDPLLHMVRNALDHGIERPDERRAAGKPPVGTLTLRAFHDAGSMVVQVL
DDGRGLDVRRIAQQAVARGLASDPARIGPEDAAGLIFEPGLSTADAVTELSGRGVGMDVVRRNIEALRGSVSVESEPGHG
TAITLRVPLTLAIIQGFKVGVGGETYILPLDAVSECLELPPEETRAGAPWGVINVRGKPLPYLRLRDHFKVAGAAPQREN
VVVVQHGAQVAGVAVDVLHGESSTVIKPLGGLVGAVAGVSGSSILGNGRVALILDVAGILRETLRRAAAQAAA

Sequences:

>Translated_553_residues
MDELEIDREALLATFLAEADETFAHMEQQLLALERTPEDDELLNALFRDVHTLKGAASLVSFDGARDVAHDLEDVLERLR
QKTLAVTDALVTLLLQSVDVLRRAVAEAEAGAGGGGASDAVLAFRARLAEAARAAVAERAAPSGAAEAPDAHEPHAPHAA
AARTLRVDVGKLDRMLNLSGEIAIARGRLGEMLERRGGVSAEDALDAHREADRLYLDLQELIMKARMVPIGPTFHQHVRT
LRDLASNLGKQARLVMEGEDVEVDTAVIEHIRDPLLHMVRNALDHGIERPDERRAAGKPPVGTLTLRAFHDAGSMVVQVL
DDGRGLDVRRIAQQAVARGLASDPARIGPEDAAGLIFEPGLSTADAVTELSGRGVGMDVVRRNIEALRGSVSVESEPGHG
TAITLRVPLTLAIIQGFKVGVGGETYILPLDAVSECLELPPEETRAGAPWGVINVRGKPLPYLRLRDHFKVAGAAPQREN
VVVVQHGAQVAGVAVDVLHGESSTVIKPLGGLVGAVAGVSGSSILGNGRVALILDVAGILRETLRRAAAQAAA
>Mature_553_residues
MDELEIDREALLATFLAEADETFAHMEQQLLALERTPEDDELLNALFRDVHTLKGAASLVSFDGARDVAHDLEDVLERLR
QKTLAVTDALVTLLLQSVDVLRRAVAEAEAGAGGGGASDAVLAFRARLAEAARAAVAERAAPSGAAEAPDAHEPHAPHAA
AARTLRVDVGKLDRMLNLSGEIAIARGRLGEMLERRGGVSAEDALDAHREADRLYLDLQELIMKARMVPIGPTFHQHVRT
LRDLASNLGKQARLVMEGEDVEVDTAVIEHIRDPLLHMVRNALDHGIERPDERRAAGKPPVGTLTLRAFHDAGSMVVQVL
DDGRGLDVRRIAQQAVARGLASDPARIGPEDAAGLIFEPGLSTADAVTELSGRGVGMDVVRRNIEALRGSVSVESEPGHG
TAITLRVPLTLAIIQGFKVGVGGETYILPLDAVSECLELPPEETRAGAPWGVINVRGKPLPYLRLRDHFKVAGAAPQREN
VVVVQHGAQVAGVAVDVLHGESSTVIKPLGGLVGAVAGVSGSSILGNGRVALILDVAGILRETLRRAAAQAAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=409, Percent_Identity=41.320293398533, Blast_Score=284, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58581; Mature: 58581

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDELEIDREALLATFLAEADETFAHMEQQLLALERTPEDDELLNALFRDVHTLKGAASLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SFDGARDVAHDLEDVLERLRQKTLAVTDALVTLLLQSVDVLRRAVAEAEAGAGGGGASDA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VLAFRARLAEAARAAVAERAAPSGAAEAPDAHEPHAPHAAAARTLRVDVGKLDRMLNLSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEEHHHHHHHHCCCC
EIAIARGRLGEMLERRGGVSAEDALDAHREADRLYLDLQELIMKARMVPIGPTFHQHVRT
CEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LRDLASNLGKQARLVMEGEDVEVDTAVIEHIRDPLLHMVRNALDHGIERPDERRAAGKPP
HHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
VGTLTLRAFHDAGSMVVQVLDDGRGLDVRRIAQQAVARGLASDPARIGPEDAAGLIFEPG
CCEEEEEEHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCC
LSTADAVTELSGRGVGMDVVRRNIEALRGSVSVESEPGHGTAITLRVPLTLAIIQGFKVG
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCHHHHHHHCCEEC
VGGETYILPLDAVSECLELPPEETRAGAPWGVINVRGKPLPYLRLRDHFKVAGAAPQREN
CCCCEEEEEHHHHHHHHHCCCHHHCCCCCCCEEEECCCCCCCHHHHCCCEECCCCCCCCC
VVVVQHGAQVAGVAVDVLHGESSTVIKPLGGLVGAVAGVSGSSILGNGRVALILDVAGIL
EEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEECCCCEEEEHHHHHHH
RETLRRAAAQAAA
HHHHHHHHHHCCC
>Mature Secondary Structure
MDELEIDREALLATFLAEADETFAHMEQQLLALERTPEDDELLNALFRDVHTLKGAASLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SFDGARDVAHDLEDVLERLRQKTLAVTDALVTLLLQSVDVLRRAVAEAEAGAGGGGASDA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VLAFRARLAEAARAAVAERAAPSGAAEAPDAHEPHAPHAAAARTLRVDVGKLDRMLNLSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHEEEHHHHHHHHCCCC
EIAIARGRLGEMLERRGGVSAEDALDAHREADRLYLDLQELIMKARMVPIGPTFHQHVRT
CEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LRDLASNLGKQARLVMEGEDVEVDTAVIEHIRDPLLHMVRNALDHGIERPDERRAAGKPP
HHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
VGTLTLRAFHDAGSMVVQVLDDGRGLDVRRIAQQAVARGLASDPARIGPEDAAGLIFEPG
CCEEEEEEHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCC
LSTADAVTELSGRGVGMDVVRRNIEALRGSVSVESEPGHGTAITLRVPLTLAIIQGFKVG
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCHHHHHHHCCEEC
VGGETYILPLDAVSECLELPPEETRAGAPWGVINVRGKPLPYLRLRDHFKVAGAAPQREN
CCCCEEEEEHHHHHHHHHCCCHHHCCCCCCCEEEECCCCCCCHHHHCCCEECCCCCCCCC
VVVVQHGAQVAGVAVDVLHGESSTVIKPLGGLVGAVAGVSGSSILGNGRVALILDVAGIL
EEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEECCCCEEEEHHHHHHH
RETLRRAAAQAAA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]