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The map label for this gene is nhaA1 [H]

Identifier: 220915653

GI number: 220915653

Start: 612030

End: 613202

Strand: Reverse

Name: nhaA1 [H]

Synonym: A2cp1_0534

Alternate gene names: 220915653

Gene position: 613202-612030 (Counterclockwise)

Preceding gene: 220915654

Following gene: 220915644

Centisome position: 12.19

GC content: 76.81

Gene sequence:

>1173_bases
GTGCCCGCATCCCACGTTCCCGACACCTCCAGGGGCAAGCAGCCCGATCGCGGGGGGCTCCCCGCCCGCTCGCGCGCGCT
CGCGCTCGCCATCCTCGTCCTGGCGCTGGCCGGCGCCGGCCTCGCCGCCGAGCTGACCCTGCTCCACGGCCGCGCCCACG
CCGGCGGCGCGTCCAGCTTCTGCGCCATCTCCGAGCGCGTGAACTGCGACAAGGTCGCCCTGAGCGCCTGGTCGTCGCTG
CTCGGGGTGCCCCTCGCGGCGTGGGGCCTCCTGGCGTACCTGGTCGTCGCCGCGCTCGCGCTCTCGGCGCTCCGGCGGCC
GCGCGGGGACGCCGGATGGCCGGCCGGGCTCCTGTTCGCCGCGTCGGCGTTCATGGCGGCCGGGGCCGTGTTCCTGGCGG
CGATCTCCGAGCTGGTGATCGGCTCGCTGTGCATCGTGTGCGCGGGCTCGTGGCTGGTGTCGTTCGCGCTCGCCGGCTGC
TCGTTCGCCCTGGCGCGGCGCGCCGGCGGCCCCGCGGCCGCGCTCCGGTCCGACGTGGCCACGCTGCGCGCGCGCCCGCT
CGCGTCGGCGACGGCCGCGCTCGCGCTCCTGGCCGCCTCGGGCGGGCTGCTGGCCCGCTACGCCGGTCCGCCACCCGCCC
CGGCGGGCGCGCCCGCCGCCGCGCCGGCCGCGAGCCTGGGCCCGCCCGGCTCGATCGTGCTGTACGAGTACAGCGACTAC
GAGTGCCCGTTCTGCGCCAGGAGCCACGAGGCCAACAAGCCCATCCTGGCGTCCCGGCCCGACGTGAAGGTGGTGCGGCG
CCACTTCCCGCTCGACGACACCTGCAACCCGAAGCTCATCCGGCCCTTCCACGTGGGCGCCTGCGATCTCGCCCGCGCGG
CCATCTGCGCCGAGGCGCAGGGCCGGTTCGAGCAGATGGACGACGCCTTGTTCCGCAACCAGGCGGAGAAGGCGCCGGTG
CGGGAGCTGGCCCGGCGGATCGGGCTCGACCTGCCGCGCTTCGAGGCCTGCCTCTCCTCGCCCGAGACCGAGAAGCGCCT
CGCCGACGACATCGAGAGCGCCATCCAGGCCGGCGTGCGCGGGACCCCGAGCTACGTGTACGGGGGCAAGGTCTACCCCG
GCGACCTCGCCACGCTGCTCGGCGCCAAGCCGGCGGCCGCGAGCGGCGGGTAG

Upstream 100 bases:

>100_bases
GGGCCCGGTTCTCGCTCCGCCTTCCGCTCGAGTCCCCCGCCTGACGGCGGGGGGCATCGCGAGGCAGGACGCCCGGGCGA
CTTCCGGTTACCATCCCCCC

Downstream 100 bases:

>100_bases
CGCTCCCTCGACGCCGCGGCACCCGCTCACCCTGAGCGTCCCTCGACTCCGCGCGGCCCCAGGGGCCGCGCTACGCTCGG
GATGAGCGAGCGAGCCGCAG

Product: Vitamin K epoxide reductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPASHVPDTSRGKQPDRGGLPARSRALALAILVLALAGAGLAAELTLLHGRAHAGGASSFCAISERVNCDKVALSAWSSL
LGVPLAAWGLLAYLVVAALALSALRRPRGDAGWPAGLLFAASAFMAAGAVFLAAISELVIGSLCIVCAGSWLVSFALAGC
SFALARRAGGPAAALRSDVATLRARPLASATAALALLAASGGLLARYAGPPPAPAGAPAAAPAASLGPPGSIVLYEYSDY
ECPFCARSHEANKPILASRPDVKVVRRHFPLDDTCNPKLIRPFHVGACDLARAAICAEAQGRFEQMDDALFRNQAEKAPV
RELARRIGLDLPRFEACLSSPETEKRLADDIESAIQAGVRGTPSYVYGGKVYPGDLATLLGAKPAAASGG

Sequences:

>Translated_390_residues
MPASHVPDTSRGKQPDRGGLPARSRALALAILVLALAGAGLAAELTLLHGRAHAGGASSFCAISERVNCDKVALSAWSSL
LGVPLAAWGLLAYLVVAALALSALRRPRGDAGWPAGLLFAASAFMAAGAVFLAAISELVIGSLCIVCAGSWLVSFALAGC
SFALARRAGGPAAALRSDVATLRARPLASATAALALLAASGGLLARYAGPPPAPAGAPAAAPAASLGPPGSIVLYEYSDY
ECPFCARSHEANKPILASRPDVKVVRRHFPLDDTCNPKLIRPFHVGACDLARAAICAEAQGRFEQMDDALFRNQAEKAPV
RELARRIGLDLPRFEACLSSPETEKRLADDIESAIQAGVRGTPSYVYGGKVYPGDLATLLGAKPAAASGG
>Mature_389_residues
PASHVPDTSRGKQPDRGGLPARSRALALAILVLALAGAGLAAELTLLHGRAHAGGASSFCAISERVNCDKVALSAWSSLL
GVPLAAWGLLAYLVVAALALSALRRPRGDAGWPAGLLFAASAFMAAGAVFLAAISELVIGSLCIVCAGSWLVSFALAGCS
FALARRAGGPAAALRSDVATLRARPLASATAALALLAASGGLLARYAGPPPAPAGAPAAAPAASLGPPGSIVLYEYSDYE
CPFCARSHEANKPILASRPDVKVVRRHFPLDDTCNPKLIRPFHVGACDLARAAICAEAQGRFEQMDDALFRNQAEKAPVR
ELARRIGLDLPRFEACLSSPETEKRLADDIESAIQAGVRGTPSYVYGGKVYPGDLATLLGAKPAAASGG

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 39929; Mature: 39798

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASHVPDTSRGKQPDRGGLPARSRALALAILVLALAGAGLAAELTLLHGRAHAGGASSF
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
CAISERVNCDKVALSAWSSLLGVPLAAWGLLAYLVVAALALSALRRPRGDAGWPAGLLFA
HHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ASAFMAAGAVFLAAISELVIGSLCIVCAGSWLVSFALAGCSFALARRAGGPAAALRSDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLRARPLASATAALALLAASGGLLARYAGPPPAPAGAPAAAPAASLGPPGSIVLYEYSDY
HHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
ECPFCARSHEANKPILASRPDVKVVRRHFPLDDTCNPKLIRPFHVGACDLARAAICAEAQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEECCEECCHHHHHHHHHHHHHH
GRFEQMDDALFRNQAEKAPVRELARRIGLDLPRFEACLSSPETEKRLADDIESAIQAGVR
HHHHHHHHHHHHCCHHCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
GTPSYVYGGKVYPGDLATLLGAKPAAASGG
CCCCEEECCEECCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PASHVPDTSRGKQPDRGGLPARSRALALAILVLALAGAGLAAELTLLHGRAHAGGASSF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
CAISERVNCDKVALSAWSSLLGVPLAAWGLLAYLVVAALALSALRRPRGDAGWPAGLLFA
HHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ASAFMAAGAVFLAAISELVIGSLCIVCAGSWLVSFALAGCSFALARRAGGPAAALRSDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLRARPLASATAALALLAASGGLLARYAGPPPAPAGAPAAAPAASLGPPGSIVLYEYSDY
HHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
ECPFCARSHEANKPILASRPDVKVVRRHFPLDDTCNPKLIRPFHVGACDLARAAICAEAQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEECCEECCHHHHHHHHHHHHHH
GRFEQMDDALFRNQAEKAPVRELARRIGLDLPRFEACLSSPETEKRLADDIESAIQAGVR
HHHHHHHHHHHHCCHHCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
GTPSYVYGGKVYPGDLATLLGAKPAAASGG
CCCCEEECCEECCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA