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The map label for this gene is kinB [H]

Identifier: 220915654

GI number: 220915654

Start: 613259

End: 614410

Strand: Reverse

Name: kinB [H]

Synonym: A2cp1_0535

Alternate gene names: 220915654

Gene position: 614410-613259 (Counterclockwise)

Preceding gene: 220915659

Following gene: 220915653

Centisome position: 12.22

GC content: 75.61

Gene sequence:

>1152_bases
ATGAGCGACCCCAGCGATCACCGCCCGCACCCGGCCGGCCCGGGACACCTGCAGGAGCAGGAGCAGCTCCTCCGCCTGCT
GGTGGACAGCGTGAAGGAGTACGCGATCTTCATGCTGGATCCGTCGGGCCACGTGCTCTCGTGGAACCCGGGCGCGGAGC
GGATCAAGGGCTACCCGGCGCACGAGATCGTGGGGCGGCACTTCGCGGTGTTCTTCACGCCCGAGGACGTGCGCCGGGGC
AAGCCGGCCGCGGAGCTGCGCGAGGCGGCCGAGCAGGGCTCCAGCGAGGACGAGGGCTGGCGGGTGCGCCGCGACGGCAC
GCGGTTCTTCGCGAGCGTGGTGGTCACCGCGCTCCGCGGCCCGGACGGCGCGCTCCGCGGGTTCGCGAAGATCACGCGCG
ACCTGACCGAGCGCCGGCGCGGGGAGGAGGCGCGGCGGAACCTGGCCGAGGCCCGCGAGGCGGTGCGGTCGCGCGACGAC
TTCCTGGCGGTCGCGTCGCACGAGCTGCGCACCCCGCTCACCTGCGTGCAGCTCGTGGCGCAGTCGCTCGCCCGGCAGAC
GCACGAGGGGCAGCCGGTCACCGGGCAGCAGGTGGAGCGGCTCCACCAGCTCCAGCGCCACGTGGCGCGGCTGGGCGAGC
TCGTGAGCGGGCTCCTCGACCTCGCCGAGATGTCGCGCGGCGCCCTGCAGCTCGAGCCGGCCCCGTTCGACCTGTCCGAG
CTGGTGCAGGAGGTGGCGGCGCGCTTCGAGCCGGACGTCCGGCGCAAGGGGACCGCGCTGAGCGTGCACGCCCCCGGGCC
GATCCCCGGCCGGTGGGACCGCCGCCGGGTGGCCGATGCGATCGCCGCGGTGCTCGGGAACGCGGTGAAGTACGGCGGGC
GCTCGCCGATCGAGGTCACCGCCAGCCGCGACGACCGCCGCGCGCTGGTCGTCATCGAGGACCGGGGGCCGGGCATCGCG
CCGGAGGACCAGTCGCGCGTGTTCGAGCGGTTCGAGCGCGCCGCGCCGGTGGCGCACTACCCCGGGCTCGGCGTCGGCCT
GTGGACCGCGCGGCAGATCCTGAACGCGCACGGCGGCGACATCGCGGTCGAGAGCGCGAGCGGCAAGGGGGCCCGGTTCT
CGCTCCGCCTTCCGCTCGAGTCCCCCGCCTGA

Upstream 100 bases:

>100_bases
TCGAACTGCCGCGGCGCCAGCCGCGCGCCGAGGCAAGATTCCCCCCGTCGGGTGCGCGCGAGCGTTCGCGCTGGCGCGGT
GCACCTCGTGCCTCGAGACG

Downstream 100 bases:

>100_bases
CGGCGGGGGGCATCGCGAGGCAGGACGCCCGGGCGACTTCCGGTTACCATCCCCCCGTGCCCGCATCCCACGTTCCCGAC
ACCTCCAGGGGCAAGCAGCC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSDPSDHRPHPAGPGHLQEQEQLLRLLVDSVKEYAIFMLDPSGHVLSWNPGAERIKGYPAHEIVGRHFAVFFTPEDVRRG
KPAAELREAAEQGSSEDEGWRVRRDGTRFFASVVVTALRGPDGALRGFAKITRDLTERRRGEEARRNLAEAREAVRSRDD
FLAVASHELRTPLTCVQLVAQSLARQTHEGQPVTGQQVERLHQLQRHVARLGELVSGLLDLAEMSRGALQLEPAPFDLSE
LVQEVAARFEPDVRRKGTALSVHAPGPIPGRWDRRRVADAIAAVLGNAVKYGGRSPIEVTASRDDRRALVVIEDRGPGIA
PEDQSRVFERFERAAPVAHYPGLGVGLWTARQILNAHGGDIAVESASGKGARFSLRLPLESPA

Sequences:

>Translated_383_residues
MSDPSDHRPHPAGPGHLQEQEQLLRLLVDSVKEYAIFMLDPSGHVLSWNPGAERIKGYPAHEIVGRHFAVFFTPEDVRRG
KPAAELREAAEQGSSEDEGWRVRRDGTRFFASVVVTALRGPDGALRGFAKITRDLTERRRGEEARRNLAEAREAVRSRDD
FLAVASHELRTPLTCVQLVAQSLARQTHEGQPVTGQQVERLHQLQRHVARLGELVSGLLDLAEMSRGALQLEPAPFDLSE
LVQEVAARFEPDVRRKGTALSVHAPGPIPGRWDRRRVADAIAAVLGNAVKYGGRSPIEVTASRDDRRALVVIEDRGPGIA
PEDQSRVFERFERAAPVAHYPGLGVGLWTARQILNAHGGDIAVESASGKGARFSLRLPLESPA
>Mature_382_residues
SDPSDHRPHPAGPGHLQEQEQLLRLLVDSVKEYAIFMLDPSGHVLSWNPGAERIKGYPAHEIVGRHFAVFFTPEDVRRGK
PAAELREAAEQGSSEDEGWRVRRDGTRFFASVVVTALRGPDGALRGFAKITRDLTERRRGEEARRNLAEAREAVRSRDDF
LAVASHELRTPLTCVQLVAQSLARQTHEGQPVTGQQVERLHQLQRHVARLGELVSGLLDLAEMSRGALQLEPAPFDLSEL
VQEVAARFEPDVRRKGTALSVHAPGPIPGRWDRRRVADAIAAVLGNAVKYGGRSPIEVTASRDDRRALVVIEDRGPGIAP
EDQSRVFERFERAAPVAHYPGLGVGLWTARQILNAHGGDIAVESASGKGARFSLRLPLESPA

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=30.5343511450382, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788549, Length=367, Percent_Identity=26.9754768392371, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=28.968253968254, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=374, Percent_Identity=24.331550802139, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=27.1317829457364, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=31.25, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=31.2252964426877, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=29.3859649122807, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=29.5081967213115, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=28.695652173913, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=30.7053941908714, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787374, Length=250, Percent_Identity=28, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=28.110599078341, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=231, Percent_Identity=26.8398268398268, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42116; Mature: 41985

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPSDHRPHPAGPGHLQEQEQLLRLLVDSVKEYAIFMLDPSGHVLSWNPGAERIKGYPA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCHHHHCCCCH
HEIVGRHFAVFFTPEDVRRGKPAAELREAAEQGSSEDEGWRVRRDGTRFFASVVVTALRG
HHHHCCCEEEEECHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
PDGALRGFAKITRDLTERRRGEEARRNLAEAREAVRSRDDFLAVASHELRTPLTCVQLVA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QSLARQTHEGQPVTGQQVERLHQLQRHVARLGELVSGLLDLAEMSRGALQLEPAPFDLSE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHH
LVQEVAARFEPDVRRKGTALSVHAPGPIPGRWDRRRVADAIAAVLGNAVKYGGRSPIEVT
HHHHHHHHCCCCHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ASRDDRRALVVIEDRGPGIAPEDQSRVFERFERAAPVAHYPGLGVGLWTARQILNAHGGD
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
IAVESASGKGARFSLRLPLESPA
EEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SDPSDHRPHPAGPGHLQEQEQLLRLLVDSVKEYAIFMLDPSGHVLSWNPGAERIKGYPA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCHHHHCCCCH
HEIVGRHFAVFFTPEDVRRGKPAAELREAAEQGSSEDEGWRVRRDGTRFFASVVVTALRG
HHHHCCCEEEEECHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
PDGALRGFAKITRDLTERRRGEEARRNLAEAREAVRSRDDFLAVASHELRTPLTCVQLVA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QSLARQTHEGQPVTGQQVERLHQLQRHVARLGELVSGLLDLAEMSRGALQLEPAPFDLSE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHH
LVQEVAARFEPDVRRKGTALSVHAPGPIPGRWDRRRVADAIAAVLGNAVKYGGRSPIEVT
HHHHHHHHCCCCHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ASRDDRRALVVIEDRGPGIAPEDQSRVFERFERAAPVAHYPGLGVGLWTARQILNAHGGD
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
IAVESASGKGARFSLRLPLESPA
EEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]