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The map label for this gene is tolQ [H]

Identifier: 220915411

GI number: 220915411

Start: 322974

End: 323732

Strand: Reverse

Name: tolQ [H]

Synonym: A2cp1_0290

Alternate gene names: 220915411

Gene position: 323732-322974 (Counterclockwise)

Preceding gene: 220915412

Following gene: 220915410

Centisome position: 6.44

GC content: 69.7

Gene sequence:

>759_bases
ATGTCGCTTCAGGTGATCCAGACGCTCCAGCAGCTGGCCGCGGCCCAGGCCACCCCCGAGGTCTCGTTCGACCTCCTGCA
CATGTGGAAGACGATGGGCCCGTTCGCGAAGTTCATCGCGGGCGTCCTGGCGGTGATGAGCATCTACTCGCTCGGCGTGA
TGGCCGAGCGCCTCGTCACCTTCGCCCGCGCGCAGAAGGCCTCGCGGCAGTTCGCCGCCGCGCTGCGCGACCTGCTCCCG
GCCGCGAAGTTCGGCGAGGCGGTCGAGCTCTCCCGCAAGCTGAAGCGCGGCCACCTGCCCAAGGTGCTCGGTCTCGCCAT
CGAGGAGTACAGCCACGGCGTCGAGGCGCTGAAGACCCACGGCCCGCGCGACGTCGGCAACTTCGACGTGATCGCCGCGG
TGAACCGCGCGGTGGAGCGCAGCTCGCTCCGCACCGTGAACGACCTGCGCCGCGGCCTGGGCGCGCTCGCCACCGTCGGC
TCGACCGCCCCGTTCGTCGGCCTCCTCGGCACCGTGGCCGGCATCATCACGGCCTTCCAGGCGATGGCCGCCACCGGCTC
CGGCGGTCTCGGCTCGGTGTCGGCCGGCATCGCCGAGGCGCTCGTGACGACCGCGTTCGGCCTCCTCGTCGCCATCCCCG
CGGTGATGATGTTCAACTACCTCACCAACCGCGTCGAGGACATGCAGGTGGACATCACCGACTCGGCCACCGAGCTGATG
GACTTCTTCATGAAGGAAGGCCGCAGCGAGGTGAAGTAG

Upstream 100 bases:

>100_bases
CCCACCGCCATCTGGGTCATCCTCCCGCTCCGGTTCACCGCCGGCTGATCCGCAGCACGCCTCTTCCGTCCCAAGTCATT
CTGCCTCCAAGGAGAGTTTC

Downstream 100 bases:

>100_bases
TCCCCCCCCCCGCGGCCCGCGAAGGAGACCTGACCGATGTCCATGGACGTTGGCGGCAAGGGGGTGAAGAGCGAGATCAA
CGTGACGCCGCTCGTCGACG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSLQVIQTLQQLAAAQATPEVSFDLLHMWKTMGPFAKFIAGVLAVMSIYSLGVMAERLVTFARAQKASRQFAAALRDLLP
AAKFGEAVELSRKLKRGHLPKVLGLAIEEYSHGVEALKTHGPRDVGNFDVIAAVNRAVERSSLRTVNDLRRGLGALATVG
STAPFVGLLGTVAGIITAFQAMAATGSGGLGSVSAGIAEALVTTAFGLLVAIPAVMMFNYLTNRVEDMQVDITDSATELM
DFFMKEGRSEVK

Sequences:

>Translated_252_residues
MSLQVIQTLQQLAAAQATPEVSFDLLHMWKTMGPFAKFIAGVLAVMSIYSLGVMAERLVTFARAQKASRQFAAALRDLLP
AAKFGEAVELSRKLKRGHLPKVLGLAIEEYSHGVEALKTHGPRDVGNFDVIAAVNRAVERSSLRTVNDLRRGLGALATVG
STAPFVGLLGTVAGIITAFQAMAATGSGGLGSVSAGIAEALVTTAFGLLVAIPAVMMFNYLTNRVEDMQVDITDSATELM
DFFMKEGRSEVK
>Mature_251_residues
SLQVIQTLQQLAAAQATPEVSFDLLHMWKTMGPFAKFIAGVLAVMSIYSLGVMAERLVTFARAQKASRQFAAALRDLLPA
AKFGEAVELSRKLKRGHLPKVLGLAIEEYSHGVEALKTHGPRDVGNFDVIAAVNRAVERSSLRTVNDLRRGLGALATVGS
TAPFVGLLGTVAGIITAFQAMAATGSGGLGSVSAGIAEALVTTAFGLLVAIPAVMMFNYLTNRVEDMQVDITDSATELMD
FFMKEGRSEVK

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=166, Percent_Identity=36.7469879518072, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789381, Length=90, Percent_Identity=44.4444444444444, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26787; Mature: 26655

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCC
>Mature Secondary Structure 
SLQVIQTLQQLAAAQATPEVSFDLLHMWKTMGPFAKFIAGVLAVMSIYSLGVMAERLVT
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FARAQKASRQFAAALRDLLPAAKFGEAVELSRKLKRGHLPKVLGLAIEEYSHGVEALKTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GPRDVGNFDVIAAVNRAVERSSLRTVNDLRRGLGALATVGSTAPFVGLLGTVAGIITAFQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AMAATGSGGLGSVSAGIAEALVTTAFGLLVAIPAVMMFNYLTNRVEDMQVDITDSATELM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHH
DFFMKEGRSEVK
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]