Click here to switch to the map view.

The map label for this gene is pleD [H]

Identifier: 220915240

GI number: 220915240

Start: 133977

End: 134363

Strand: Reverse

Name: pleD [H]

Synonym: A2cp1_0119

Alternate gene names: 220915240

Gene position: 134363-133977 (Counterclockwise)

Preceding gene: 220915244

Following gene: 220915234

Centisome position: 2.67

GC content: 73.13

Gene sequence:

>387_bases
ATGGCCCCCGAACCCTCCCCGCTGCGCATCCTGGTCGCCGAGGACGATCCCGCGGTGGCCCGGCTGTACACCGCCTACGC
GCAGAGCCGCGGGCACACCGTCCTCGTCGCCCACGACGGCGCCGAGGCGTTCAGCGCCGCGGCCGACCAGGGGCCCGACC
TCATCCTCCTCGACGTGGCCATGCCGAAGGTGGACGGCCGCGACGCGCTCCGCCGCCTGAAGGCCGACCCGCGGACCCAG
GGCATCCCCGTCCTCGTGATCAGCGCGCACGGGTCCGACCAGAACCTCCGCGAGCTGATGCTCGGGCTCGGCGCCTGGGA
CGTGATGGAGAAGCCGGTGGATCTCCAGATCGCGTTCAACAAGGCCGAGCGGCTGGCGCGCCGGTAG

Upstream 100 bases:

>100_bases
CGGCCCGCCGGTGGCCGACCTGCCGGACATGCCCCCGCCCGCACGAGGCACGACGGGGCGGTCGTTGCGCCGGCCGGCGG
CGGAGGTATCCTCCCCCCGG

Downstream 100 bases:

>100_bases
TCCGCCGAGCCCGGCCGGACCTTCGATCATCCCGAGCGTAGCCCGCCGCAGGCGGGCGGAGTCGAGGGACCGCCGCAGGC
GGGCGGAGTCGAGGGACCGC

Product: response regulator receiver protein

Products: NA

Alternate protein names: Stalked cell differentiation-controlling protein; Diguanylate cyclase; DGC; Diguanylate kinase [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MAPEPSPLRILVAEDDPAVARLYTAYAQSRGHTVLVAHDGAEAFSAAADQGPDLILLDVAMPKVDGRDALRRLKADPRTQ
GIPVLVISAHGSDQNLRELMLGLGAWDVMEKPVDLQIAFNKAERLARR

Sequences:

>Translated_128_residues
MAPEPSPLRILVAEDDPAVARLYTAYAQSRGHTVLVAHDGAEAFSAAADQGPDLILLDVAMPKVDGRDALRRLKADPRTQ
GIPVLVISAHGSDQNLRELMLGLGAWDVMEKPVDLQIAFNKAERLARR
>Mature_127_residues
APEPSPLRILVAEDDPAVARLYTAYAQSRGHTVLVAHDGAEAFSAAADQGPDLILLDVAMPKVDGRDALRRLKADPRTQG
IPVLVISAHGSDQNLRELMLGLGAWDVMEKPVDLQIAFNKAERLARR

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Phosphorylated PleD localizes to the differentiating pole [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 response regulatory domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR000160
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00990 GGDEF; PF00072 Response_reg [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 13875; Mature: 13744

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEPSPLRILVAEDDPAVARLYTAYAQSRGHTVLVAHDGAEAFSAAADQGPDLILLDVA
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCEEEEEEC
MPKVDGRDALRRLKADPRTQGIPVLVISAHGSDQNLRELMLGLGAWDVMEKPVDLQIAFN
CCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHCCCCEEEEEEC
KAERLARR
HHHHHHCC
>Mature Secondary Structure 
APEPSPLRILVAEDDPAVARLYTAYAQSRGHTVLVAHDGAEAFSAAADQGPDLILLDVA
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCCCEEEEEEC
MPKVDGRDALRRLKADPRTQGIPVLVISAHGSDQNLRELMLGLGAWDVMEKPVDLQIAFN
CCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHCCCCEEEEEEC
KAERLARR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA