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The map label for this gene is 220915234

Identifier: 220915234

GI number: 220915234

Start: 125456

End: 127096

Strand: Reverse

Name: 220915234

Synonym: A2cp1_0113

Alternate gene names: NA

Gene position: 127096-125456 (Counterclockwise)

Preceding gene: 220915240

Following gene: 220915233

Centisome position: 2.53

GC content: 75.62

Gene sequence:

>1641_bases
GTGCGGATCGTGCCCCTGGGCGGGCTCGGGGAGATCGGGATGAACTGCATGGCCGTCGAGTGCGACGGCCGGATCGCCGT
GGTGGACTGCGGCGTGCTCTTCCCGAACGAGAGCCTGGGCGTCGACCTGATCGCGCCGGACCTCTCCTGGCTGCGCGAGC
GGCGCGAGCAGGTGGGCGCGGTGTTCCTCACGCACGGCCACGAGGATCACCTGGGCGCGCTGCCGTTCCTGCTCCGGGAG
GTCCCGGTGCCGGTCTACGGCACGCGCTTCACGCTCGCGCTGCTCCGCCCGCGGCTCGACGAGGCGGGCGTGCGCGCCGA
TCTGCGCGAGGTCCGCCCCGGCGACGTCCGGCCCGCCGGCGACGCCTCGCCCATCGCGGCCGAGTTCTTCTCGGTCACCC
ACTCCATCCCCGACGCCTGCGGCCTGGCGCTCTCGACGCCGCAGGGGACGCTGCTCCACTCCGGCGACTTCAAGATCGAC
CCGGCGCCGGTGCGCGGCCCCGGCATGGATCTCGGCCGCATCGAGGCGCTCGGGCGCAAGGGCGTGCGGCTCCTGCTCTC
CGACTCCACCAACGCCGAGCGCGAGGGGACCTCGCTCTCGGAGTCGCAGGTGGGCCCGGCGCTGGAGCAGGCGTTCGAGC
TGGCGCGCGGCCGGGTGTTCGTGGCCTGCTTCGCCTCCAACGTCCACCGGCTGCAGCAGATCGTGGACGCGGCGCGCGCC
TTCGGCCGGCGGGTCGCGTTCCTGGGCCGCTCCATGGAGGCGAACGCGCGGCTCGCGCAGGAGCTCGGGTACCTCGAGCT
GCCCGGCTGGATGCCGGTGTCGCCCGAGGAGGCGAGGACGCTGCCGCCGCGCGAGCTGTGCGTCCTCACCACCGGCACCC
AGGGCGAGCCGCGCAGCGCGCTCGCGCGCCTCGCCCGCGGCGAGCACCCGGACCTCGCCGTCTCGCCGGGCGACCTGGTG
GTGCTGTCGTCGCGCTTCATCCCCGGGAACGAGATCGCGATCGGCCAGGTGGTGAACGAGCTCTGCCGGCGCGGCGCCGA
GGTCGCGTACGAGGGCCTCGCGCCGCTCCACGTGTCCGGCCACGCCCAGGCGGACGAGCAGCGCCGACTGATCCGGCTCG
CCCGCCCGGCCCACTTCGTGCCCATCCACGGCGAGTACCGGCACCTCTCCCGGCACGCCGCCCACGCCGCGGCCGAGGGC
GTGGCCGGACGCGACGTGCTGGTGGACGGGCAGGTGCTGGAGCTCGCCGACGCCGGCGTGCGGGTGCTGGACGAGCCGGT
GGCGACCGGCCGCGTGTACACGGACCGCGACGCGCTCCTCGGCGCCGACATCGGCGCGCTGGTGGTGCGCGACCGCCGCC
TGCTCGCCGAGACCGGCCTGTGCATCGCGGTGCTGGCCATCGAGCGGACCACCGGCGCGGTGGTGCGCGGCCCGGAGCTG
TTCGCGCGCGGCGTGGCCGGGTTCGAGGGGGCGGAGGAGGAGCTCCGCGCCGAGATCCTGGCCGGGCTGGGCGACCTCTC
GCCGAAGGCGCGCACCGATCCCGCCGAGGTGCAGGAGGCGGTGCGCCTCGCGGTGCGCCGCTTCTTCCGCCGGACCACCG
GCAAGAAGCCGCCCGTGCTACCGGTGGTCCTGGAGCTGTGA

Upstream 100 bases:

>100_bases
CAGGCTACCACGGTCGCCGGGGGGCCGCAGCCCGGAGGGCCGGCGCGCGCGCGCTGCGTCCGGGCGCGACCGGCGGTAGA
TTGGGCCCGTGGCGGCGCCG

Downstream 100 bases:

>100_bases
ACCGGGCGGCCCCGCGCCGCCGAGAGCCTGGAGGCAGCCGTGCCGAGCTTCGACGTCGTGTCCGAGGTGGACCTGATGGA
GGTCGAGAACGCGTTCAACC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MRIVPLGGLGEIGMNCMAVECDGRIAVVDCGVLFPNESLGVDLIAPDLSWLRERREQVGAVFLTHGHEDHLGALPFLLRE
VPVPVYGTRFTLALLRPRLDEAGVRADLREVRPGDVRPAGDASPIAAEFFSVTHSIPDACGLALSTPQGTLLHSGDFKID
PAPVRGPGMDLGRIEALGRKGVRLLLSDSTNAEREGTSLSESQVGPALEQAFELARGRVFVACFASNVHRLQQIVDAARA
FGRRVAFLGRSMEANARLAQELGYLELPGWMPVSPEEARTLPPRELCVLTTGTQGEPRSALARLARGEHPDLAVSPGDLV
VLSSRFIPGNEIAIGQVVNELCRRGAEVAYEGLAPLHVSGHAQADEQRRLIRLARPAHFVPIHGEYRHLSRHAAHAAAEG
VAGRDVLVDGQVLELADAGVRVLDEPVATGRVYTDRDALLGADIGALVVRDRRLLAETGLCIAVLAIERTTGAVVRGPEL
FARGVAGFEGAEEELRAEILAGLGDLSPKARTDPAEVQEAVRLAVRRFFRRTTGKKPPVLPVVLEL

Sequences:

>Translated_546_residues
MRIVPLGGLGEIGMNCMAVECDGRIAVVDCGVLFPNESLGVDLIAPDLSWLRERREQVGAVFLTHGHEDHLGALPFLLRE
VPVPVYGTRFTLALLRPRLDEAGVRADLREVRPGDVRPAGDASPIAAEFFSVTHSIPDACGLALSTPQGTLLHSGDFKID
PAPVRGPGMDLGRIEALGRKGVRLLLSDSTNAEREGTSLSESQVGPALEQAFELARGRVFVACFASNVHRLQQIVDAARA
FGRRVAFLGRSMEANARLAQELGYLELPGWMPVSPEEARTLPPRELCVLTTGTQGEPRSALARLARGEHPDLAVSPGDLV
VLSSRFIPGNEIAIGQVVNELCRRGAEVAYEGLAPLHVSGHAQADEQRRLIRLARPAHFVPIHGEYRHLSRHAAHAAAEG
VAGRDVLVDGQVLELADAGVRVLDEPVATGRVYTDRDALLGADIGALVVRDRRLLAETGLCIAVLAIERTTGAVVRGPEL
FARGVAGFEGAEEELRAEILAGLGDLSPKARTDPAEVQEAVRLAVRRFFRRTTGKKPPVLPVVLEL
>Mature_546_residues
MRIVPLGGLGEIGMNCMAVECDGRIAVVDCGVLFPNESLGVDLIAPDLSWLRERREQVGAVFLTHGHEDHLGALPFLLRE
VPVPVYGTRFTLALLRPRLDEAGVRADLREVRPGDVRPAGDASPIAAEFFSVTHSIPDACGLALSTPQGTLLHSGDFKID
PAPVRGPGMDLGRIEALGRKGVRLLLSDSTNAEREGTSLSESQVGPALEQAFELARGRVFVACFASNVHRLQQIVDAARA
FGRRVAFLGRSMEANARLAQELGYLELPGWMPVSPEEARTLPPRELCVLTTGTQGEPRSALARLARGEHPDLAVSPGDLV
VLSSRFIPGNEIAIGQVVNELCRRGAEVAYEGLAPLHVSGHAQADEQRRLIRLARPAHFVPIHGEYRHLSRHAAHAAAEG
VAGRDVLVDGQVLELADAGVRVLDEPVATGRVYTDRDALLGADIGALVVRDRRLLAETGLCIAVLAIERTTGAVVRGPEL
FARGVAGFEGAEEELRAEILAGLGDLSPKARTDPAEVQEAVRLAVRRFFRRTTGKKPPVLPVVLEL

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 58636; Mature: 58636

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVPLGGLGEIGMNCMAVECDGRIAVVDCGVLFPNESLGVDLIAPDLSWLRERREQVGA
CEEECCCCCHHHCCCEEEEEECCEEEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHCE
VFLTHGHEDHLGALPFLLREVPVPVYGTRFTLALLRPRLDEAGVRADLREVRPGDVRPAG
EEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
DASPIAAEFFSVTHSIPDACGLALSTPQGTLLHSGDFKIDPAPVRGPGMDLGRIEALGRK
CCCHHHHHHHHHHHCCCHHHCCEECCCCCCEEECCCCEECCCCCCCCCCCHHHHHHHCCC
GVRLLLSDSTNAEREGTSLSESQVGPALEQAFELARGRVFVACFASNVHRLQQIVDAARA
CEEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH
FGRRVAFLGRSMEANARLAQELGYLELPGWMPVSPEEARTLPPRELCVLTTGTQGEPRSA
HHHHHHHHCCCCCHHHHHHHHCCCEECCCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHH
LARLARGEHPDLAVSPGDLVVLSSRFIPGNEIAIGQVVNELCRRGAEVAYEGLAPLHVSG
HHHHHCCCCCCEEECCCCEEEEECCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCEEECC
HAQADEQRRLIRLARPAHFVPIHGEYRHLSRHAAHAAAEGVAGRDVLVDGQVLELADAGV
CCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEHHHCCH
RVLDEPVATGRVYTDRDALLGADIGALVVRDRRLLAETGLCIAVLAIERTTGAVVRGPEL
HHHCCCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEECHHH
FARGVAGFEGAEEELRAEILAGLGDLSPKARTDPAEVQEAVRLAVRRFFRRTTGKKPPVL
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVVLEL
EEEEEC
>Mature Secondary Structure
MRIVPLGGLGEIGMNCMAVECDGRIAVVDCGVLFPNESLGVDLIAPDLSWLRERREQVGA
CEEECCCCCHHHCCCEEEEEECCEEEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHCE
VFLTHGHEDHLGALPFLLREVPVPVYGTRFTLALLRPRLDEAGVRADLREVRPGDVRPAG
EEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
DASPIAAEFFSVTHSIPDACGLALSTPQGTLLHSGDFKIDPAPVRGPGMDLGRIEALGRK
CCCHHHHHHHHHHHCCCHHHCCEECCCCCCEEECCCCEECCCCCCCCCCCHHHHHHHCCC
GVRLLLSDSTNAEREGTSLSESQVGPALEQAFELARGRVFVACFASNVHRLQQIVDAARA
CEEEEEECCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH
FGRRVAFLGRSMEANARLAQELGYLELPGWMPVSPEEARTLPPRELCVLTTGTQGEPRSA
HHHHHHHHCCCCCHHHHHHHHCCCEECCCCCCCCCHHHCCCCCCCEEEEECCCCCCHHHH
LARLARGEHPDLAVSPGDLVVLSSRFIPGNEIAIGQVVNELCRRGAEVAYEGLAPLHVSG
HHHHHCCCCCCEEECCCCEEEEECCCCCCCCEEHHHHHHHHHHCCHHHHHCCCCCEEECC
HAQADEQRRLIRLARPAHFVPIHGEYRHLSRHAAHAAAEGVAGRDVLVDGQVLELADAGV
CCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEHHHCCH
RVLDEPVATGRVYTDRDALLGADIGALVVRDRRLLAETGLCIAVLAIERTTGAVVRGPEL
HHHCCCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEECHHH
FARGVAGFEGAEEELRAEILAGLGDLSPKARTDPAEVQEAVRLAVRRFFRRTTGKKPPVL
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVVLEL
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]