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The map label for this gene is dnaC [H]

Identifier: 220915218

GI number: 220915218

Start: 106949

End: 108370

Strand: Reverse

Name: dnaC [H]

Synonym: A2cp1_0097

Alternate gene names: 220915218

Gene position: 108370-106949 (Counterclockwise)

Preceding gene: 220915220

Following gene: 220915213

Centisome position: 2.15

GC content: 70.75

Gene sequence:

>1422_bases
ATGGCCGAATCGGATCCTGCCCGCCGCGTCGCCGAAGCCGGCGTCTCCCCCCTGCGCTCCGCGCGCGATCTCCCCCACAG
CCTCGAGGCCGAGCAGGCGGTGCTGGGCGCGATCCTGGTGGAGGAGACCGCCTTCGACCAGGTGGCGGCGCTGCTCCGGG
CCGGCGACTTCTACCTGCTCGCCCACCAGCACGTGTACGGCGCGTGCGAGGAGCTGGCCCGCGAGTCGAAGACGCTCGAC
CCCATCCTGATCCAGCAGCGGCTCGACGCGAAGGGGCTGCTCGGCTCGGCGGTCCCGCACGAGCTCCCGCTCACGCTGGC
GCGCGCCATCGGCACCGCGTCGAACGTGGGCCACTACGCGCGCACCGTGCAGGACCTGGCCCGGCTTCGCGTGATGATGC
TCACCGCGCAGCGGCTGGTGGAGCGCGGCTACGAGGCGGGCGCGAACGTCCAGCACTTCCTGGACGCCGCCCAGCAGGAG
GTGTTCGGCGCGGCGCAGGGCACCAGCGTCGACACGCTGAAGAAGATCTCCGAGCCGGTGCTGCGCGCGCTCGAGAACCT
CGAGGCGGTGCAGAAGCGGGTGCAGGCCGGCCTGTCGCCCATCACCGGCGTGCCCACCGGCATCCAGACGCTCGACCGGA
ACACGCTCGGGCTGCAGCCCGGCACGCTCACCGTCCTCGCCGCCCGCCCGTCGGTCGGCAAGACCGCCTTCGCGCTCAAC
ATCGCCACCCACGCCGCCACCAAGGCGCAGCGCAAGGTGGCGTTCTTCTCGCTGGAGATGCCCGCCGACCAGCTCGCGCT
CCGCATGCTCGCGTCCGAGGGCAAGCTCGACTGGCGCAAGCTCTCGCAGGGCCAGCTCTCCCGGCACGACTGGGACAAGC
TCGCCACCCAGGCCGACCGCATCGGCGCCGCCAGCCTGTGGCTCGACGACAACTTCGTGCTCACCCCCGTCGAGCTGCGC
TCGAAGTGCCGCAAGCTGAAGCGCGAGAACGGCGGGCTCGACCTGGTGATGATCGACTACCTGCAGCTCATGCACGCGCC
CAGCGATCGCTCCAACCAGTCGCGCGAGCAGGAGATCGCCACCATCAGCCGCTCGCTCAAGTCGCTGGCGAAGGAGCTCG
AGTGCCCCATCGTGGCGCTCTCGCAGCTGAACCGCAGCGTGGAGAAGCGCAAGGGCGAGCCCCCCATGCTCTCCGACCTC
CGCGAGTCCGGCGCCATCGAGCAGGACGCCGACATCGTGATGTTCCTGCACCGCGCGGAGGAGGACAACAAGGACGTCCA
GCAGGGCACCGCCGCCGGCGACACGCTCCCCGTGCAGCTCATCGTGGCGAAGCAGCGCCAGGGCCCCACCTGCACCATCG
ACCTGGTGTTCTTCAAGAGCACCACCTACTTCGCCGAGATGGACCGCCGGCCCCAGCAGTAG

Upstream 100 bases:

>100_bases
CCACAGCCTTTCCACCGCGTCTTTCCATGCGTTTTCGGCGGTTATCCACCGCACATCGACAATGATCGGGTCACAGTCGG
CTGGTAGGCTGCGCCGCTCG

Downstream 100 bases:

>100_bases
GCCCGTCGGCGCACCCGCCCGTCATCCCCCGACCGCCCGCGGGACCTCGTCGAGCGAGAGCAGCCCCCGGCATCTCCAGC
CCGTGGAGAGCAGCCAGGTG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MAESDPARRVAEAGVSPLRSARDLPHSLEAEQAVLGAILVEETAFDQVAALLRAGDFYLLAHQHVYGACEELARESKTLD
PILIQQRLDAKGLLGSAVPHELPLTLARAIGTASNVGHYARTVQDLARLRVMMLTAQRLVERGYEAGANVQHFLDAAQQE
VFGAAQGTSVDTLKKISEPVLRALENLEAVQKRVQAGLSPITGVPTGIQTLDRNTLGLQPGTLTVLAARPSVGKTAFALN
IATHAATKAQRKVAFFSLEMPADQLALRMLASEGKLDWRKLSQGQLSRHDWDKLATQADRIGAASLWLDDNFVLTPVELR
SKCRKLKRENGGLDLVMIDYLQLMHAPSDRSNQSREQEIATISRSLKSLAKELECPIVALSQLNRSVEKRKGEPPMLSDL
RESGAIEQDADIVMFLHRAEEDNKDVQQGTAAGDTLPVQLIVAKQRQGPTCTIDLVFFKSTTYFAEMDRRPQQ

Sequences:

>Translated_473_residues
MAESDPARRVAEAGVSPLRSARDLPHSLEAEQAVLGAILVEETAFDQVAALLRAGDFYLLAHQHVYGACEELARESKTLD
PILIQQRLDAKGLLGSAVPHELPLTLARAIGTASNVGHYARTVQDLARLRVMMLTAQRLVERGYEAGANVQHFLDAAQQE
VFGAAQGTSVDTLKKISEPVLRALENLEAVQKRVQAGLSPITGVPTGIQTLDRNTLGLQPGTLTVLAARPSVGKTAFALN
IATHAATKAQRKVAFFSLEMPADQLALRMLASEGKLDWRKLSQGQLSRHDWDKLATQADRIGAASLWLDDNFVLTPVELR
SKCRKLKRENGGLDLVMIDYLQLMHAPSDRSNQSREQEIATISRSLKSLAKELECPIVALSQLNRSVEKRKGEPPMLSDL
RESGAIEQDADIVMFLHRAEEDNKDVQQGTAAGDTLPVQLIVAKQRQGPTCTIDLVFFKSTTYFAEMDRRPQQ
>Mature_472_residues
AESDPARRVAEAGVSPLRSARDLPHSLEAEQAVLGAILVEETAFDQVAALLRAGDFYLLAHQHVYGACEELARESKTLDP
ILIQQRLDAKGLLGSAVPHELPLTLARAIGTASNVGHYARTVQDLARLRVMMLTAQRLVERGYEAGANVQHFLDAAQQEV
FGAAQGTSVDTLKKISEPVLRALENLEAVQKRVQAGLSPITGVPTGIQTLDRNTLGLQPGTLTVLAARPSVGKTAFALNI
ATHAATKAQRKVAFFSLEMPADQLALRMLASEGKLDWRKLSQGQLSRHDWDKLATQADRIGAASLWLDDNFVLTPVELRS
KCRKLKRENGGLDLVMIDYLQLMHAPSDRSNQSREQEIATISRSLKSLAKELECPIVALSQLNRSVEKRKGEPPMLSDLR
ESGAIEQDADIVMFLHRAEEDNKDVQQGTAAGDTLPVQLIVAKQRQGPTCTIDLVFFKSTTYFAEMDRRPQQ

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=446, Percent_Identity=39.6860986547085, Blast_Score=308, Evalue=7e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51856; Mature: 51725

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESDPARRVAEAGVSPLRSARDLPHSLEAEQAVLGAILVEETAFDQVAALLRAGDFYLL
CCCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AHQHVYGACEELARESKTLDPILIQQRLDAKGLLGSAVPHELPLTLARAIGTASNVGHYA
EHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHH
RTVQDLARLRVMMLTAQRLVERGYEAGANVQHFLDAAQQEVFGAAQGTSVDTLKKISEPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRALENLEAVQKRVQAGLSPITGVPTGIQTLDRNTLGLQPGTLTVLAARPSVGKTAFALN
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEE
IATHAATKAQRKVAFFSLEMPADQLALRMLASEGKLDWRKLSQGQLSRHDWDKLATQADR
HHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
IGAASLWLDDNFVLTPVELRSKCRKLKRENGGLDLVMIDYLQLMHAPSDRSNQSREQEIA
CCCEEEEECCCEEECCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHH
TISRSLKSLAKELECPIVALSQLNRSVEKRKGEPPMLSDLRESGAIEQDADIVMFLHRAE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHEEHHHHCC
EDNKDVQQGTAAGDTLPVQLIVAKQRQGPTCTIDLVFFKSTTYFAEMDRRPQQ
CCCHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEEECCHHHHHHCCCCCC
>Mature Secondary Structure 
AESDPARRVAEAGVSPLRSARDLPHSLEAEQAVLGAILVEETAFDQVAALLRAGDFYLL
CCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AHQHVYGACEELARESKTLDPILIQQRLDAKGLLGSAVPHELPLTLARAIGTASNVGHYA
EHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHH
RTVQDLARLRVMMLTAQRLVERGYEAGANVQHFLDAAQQEVFGAAQGTSVDTLKKISEPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRALENLEAVQKRVQAGLSPITGVPTGIQTLDRNTLGLQPGTLTVLAARPSVGKTAFALN
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEE
IATHAATKAQRKVAFFSLEMPADQLALRMLASEGKLDWRKLSQGQLSRHDWDKLATQADR
HHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
IGAASLWLDDNFVLTPVELRSKCRKLKRENGGLDLVMIDYLQLMHAPSDRSNQSREQEIA
CCCEEEEECCCEEECCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHH
TISRSLKSLAKELECPIVALSQLNRSVEKRKGEPPMLSDLRESGAIEQDADIVMFLHRAE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHEEHHHHCC
EDNKDVQQGTAAGDTLPVQLIVAKQRQGPTCTIDLVFFKSTTYFAEMDRRPQQ
CCCHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEEEEECCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]