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The map label for this gene is sotB [H]

Identifier: 220905488

GI number: 220905488

Start: 2683585

End: 2684775

Strand: Reverse

Name: sotB [H]

Synonym: Ddes_2226

Alternate gene names: 220905488

Gene position: 2684775-2683585 (Counterclockwise)

Preceding gene: 220905492

Following gene: 220905487

Centisome position: 93.43

GC content: 57.68

Gene sequence:

>1191_bases
ATGACCACCATAAAAACTCCGGAGGGAAGGCGCCTCTGGGTTCCTGTTTTCACGCTTGCCCTGGCTGCTTTCATTTTTGT
TACCACCGAGATACTGCCCATCGGGCTGTTGCCGGAAATTGCCGCGGACCTCGGCGAAACAGAGGCCTTCACCGGGCTTC
TTGTGGCTGTATATGCCTGGGTTGTGGCCTTGCTGTCGCTGCCCCTGACTGCTCTGACGGCCCGTTTTGAACGGCGCAAA
CTGCTGCTCTGCCTGTTTGGCGTATTCATTGCGGGCCATGTGCTTTCGGCTTTTGCGTTCAATTTTACCACCCTCATGAT
TGCCCGCATATGCGTGGCAAACGCTCACGCCGTATTCTGGTCAATCGCAAGCCCCATCGTGGTGCGCGTAACGCCGCCGG
CACTCAAGGCCAAGGGGCTTGCCATCATTATTGTAGGCGGTTCGCTGGCGACGGTGCTGGGGGTTCCGTTCAGCACGGTC
ATCGGCCAGCATTTCGGCTGGCGGGCAGCGTTTTTGATCATCGGGGCTATGGCCTTCTGCATTGCGCTGATTTTGTGGCG
ACTGCTGCCGACGCTTGAATCCAAGGATACGGGATCGTTCAAAAGCGTCCCTGCCCTGTTTCGCAACAAGGAGCTTTCAC
TGCTCTATTTGCAGACCATGCTGGCTGTGACTGGGCATTTTGTGGCCTATACCTATCTGGCGCCCCTGCTCATCCAGGTG
GGCGGCTTTACGGAAGGGGCCGTGCCGCTGTTCTTGTTGATTATGGGCCTGTCGGGCATTGCGGGCAGCATGCTTGCCGC
GCGGCTGGTGGGCAACGGGGCAAAATTCGTCTTTACTGTGCCGCCTGTGGCAATTTTTCTTTGCCTGCTGGTGCTGAACG
TTTCCATTGACAGCATCCTGCTTATCGTGCCGCTATGCATTGTATGGGGAGGCAGCATGGCGGTGCTGGGCCTGCTGTTT
CAGAGCAGGATACTTGAAATCGCGGCGCACTCCGCCGATATCGCCACATCAATATATTCGGGTATTTTCAACGTGGGCAT
CGGCGGCGGTGCGTTTATCGGCAGTATGGTGTTCAACAAGCTTGGGCTGGGCATGACGGGATACGCGGGCGCGGCGTTCT
TTTTCGCGACCATTCTGGTCAGCCTGTATGCTGCGCGGATCGGGCGCAGCGAAGGTCCGGCCGCAGGCTAA

Upstream 100 bases:

>100_bases
AATGACCGGCTGCGTCCGTTGCATTCTGCAGGGGGCGGGCGTATGCAGCACCCCGTTATTTTGCCCGCATATGGGCATAA
GACAGATATAAGGACTGACT

Downstream 100 bases:

>100_bases
GGGCGGCCCGCAGGCACATTGCCCGGGACCGTCCGGGCTGGTTCATACCCGGAAGAGCCTGCAATATCCGGTAATGTCCG
GCAATATCCGGGTATGCCCA

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTTIKTPEGRRLWVPVFTLALAAFIFVTTEILPIGLLPEIAADLGETEAFTGLLVAVYAWVVALLSLPLTALTARFERRK
LLLCLFGVFIAGHVLSAFAFNFTTLMIARICVANAHAVFWSIASPIVVRVTPPALKAKGLAIIIVGGSLATVLGVPFSTV
IGQHFGWRAAFLIIGAMAFCIALILWRLLPTLESKDTGSFKSVPALFRNKELSLLYLQTMLAVTGHFVAYTYLAPLLIQV
GGFTEGAVPLFLLIMGLSGIAGSMLAARLVGNGAKFVFTVPPVAIFLCLLVLNVSIDSILLIVPLCIVWGGSMAVLGLLF
QSRILEIAAHSADIATSIYSGIFNVGIGGGAFIGSMVFNKLGLGMTGYAGAAFFFATILVSLYAARIGRSEGPAAG

Sequences:

>Translated_396_residues
MTTIKTPEGRRLWVPVFTLALAAFIFVTTEILPIGLLPEIAADLGETEAFTGLLVAVYAWVVALLSLPLTALTARFERRK
LLLCLFGVFIAGHVLSAFAFNFTTLMIARICVANAHAVFWSIASPIVVRVTPPALKAKGLAIIIVGGSLATVLGVPFSTV
IGQHFGWRAAFLIIGAMAFCIALILWRLLPTLESKDTGSFKSVPALFRNKELSLLYLQTMLAVTGHFVAYTYLAPLLIQV
GGFTEGAVPLFLLIMGLSGIAGSMLAARLVGNGAKFVFTVPPVAIFLCLLVLNVSIDSILLIVPLCIVWGGSMAVLGLLF
QSRILEIAAHSADIATSIYSGIFNVGIGGGAFIGSMVFNKLGLGMTGYAGAAFFFATILVSLYAARIGRSEGPAAG
>Mature_395_residues
TTIKTPEGRRLWVPVFTLALAAFIFVTTEILPIGLLPEIAADLGETEAFTGLLVAVYAWVVALLSLPLTALTARFERRKL
LLCLFGVFIAGHVLSAFAFNFTTLMIARICVANAHAVFWSIASPIVVRVTPPALKAKGLAIIIVGGSLATVLGVPFSTVI
GQHFGWRAAFLIIGAMAFCIALILWRLLPTLESKDTGSFKSVPALFRNKELSLLYLQTMLAVTGHFVAYTYLAPLLIQVG
GFTEGAVPLFLLIMGLSGIAGSMLAARLVGNGAKFVFTVPPVAIFLCLLVLNVSIDSILLIVPLCIVWGGSMAVLGLLFQ
SRILEIAAHSADIATSIYSGIFNVGIGGGAFIGSMVFNKLGLGMTGYAGAAFFFATILVSLYAARIGRSEGPAAG

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=380, Percent_Identity=42.3684210526316, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI145693198, Length=356, Percent_Identity=26.9662921348315, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787947, Length=345, Percent_Identity=28.695652173913, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786595, Length=258, Percent_Identity=24.4186046511628, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41843; Mature: 41712

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIKTPEGRRLWVPVFTLALAAFIFVTTEILPIGLLPEIAADLGETEAFTGLLVAVYAW
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHH
VVALLSLPLTALTARFERRKLLLCLFGVFIAGHVLSAFAFNFTTLMIARICVANAHAVFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIASPIVVRVTPPALKAKGLAIIIVGGSLATVLGVPFSTVIGQHFGWRAAFLIIGAMAFC
HHCCCEEEEECCCCHHHCCEEEEEECCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHH
IALILWRLLPTLESKDTGSFKSVPALFRNKELSLLYLQTMLAVTGHFVAYTYLAPLLIQV
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGFTEGAVPLFLLIMGLSGIAGSMLAARLVGNGAKFVFTVPPVAIFLCLLVLNVSIDSIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHH
LIVPLCIVWGGSMAVLGLLFQSRILEIAAHSADIATSIYSGIFNVGIGGGAFIGSMVFNK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGLGMTGYAGAAFFFATILVSLYAARIGRSEGPAAG
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTIKTPEGRRLWVPVFTLALAAFIFVTTEILPIGLLPEIAADLGETEAFTGLLVAVYAW
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHH
VVALLSLPLTALTARFERRKLLLCLFGVFIAGHVLSAFAFNFTTLMIARICVANAHAVFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIASPIVVRVTPPALKAKGLAIIIVGGSLATVLGVPFSTVIGQHFGWRAAFLIIGAMAFC
HHCCCEEEEECCCCHHHCCEEEEEECCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHH
IALILWRLLPTLESKDTGSFKSVPALFRNKELSLLYLQTMLAVTGHFVAYTYLAPLLIQV
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGFTEGAVPLFLLIMGLSGIAGSMLAARLVGNGAKFVFTVPPVAIFLCLLVLNVSIDSIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHH
LIVPLCIVWGGSMAVLGLLFQSRILEIAAHSADIATSIYSGIFNVGIGGGAFIGSMVFNK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGLGMTGYAGAAFFFATILVSLYAARIGRSEGPAAG
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA