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The map label for this gene is lldP [C]

Identifier: 220905431

GI number: 220905431

Start: 2613690

End: 2615378

Strand: Reverse

Name: lldP [C]

Synonym: Ddes_2169

Alternate gene names: 220905431

Gene position: 2615378-2613690 (Counterclockwise)

Preceding gene: 220905432

Following gene: 220905426

Centisome position: 91.02

GC content: 58.85

Gene sequence:

>1689_bases
ATGTCTGTTGGAATGTTGGCCTTACTGGCGGTTATTCCGATTCTTGTGGCACTGGTCCTGATGGTGGGGCTGCGCTGGCC
CGCCACGCGGGCCATGCCGCTTGCGTGGCTTGTTTGTGCCGTCAGTGGCGTGATCGGCTGGAAACTGGACCTGTTGTACC
TTGCGGCCCTCTCGCTGCAGGGCGTGGTTGTGGCAGTTGGTGTTCTGATTATTGTTTTTGGTGCCATTCTCATCCTGTAT
ACTCTGGAAGAGAGCGGCGGCATGGAAACCATTCAGCACGGCATGCAGGGCGTCAGCCGGGACCGGCGTATCCAGGCCAT
CATCATCGGCTTCATGTTCGCGGCCTTTATTGAAGGCGCGGCCGGTTTCGGCACGCCTGCGGCCCTGGCAGCCCCGCTTT
TGCTGGCCCTTGGCTTTCCGGCCATGGCTGCCGCCGTTATCTGCCTTGTGTTCAACTCTGTGCCTGTAACCTTCGGCGCT
GTGGGAACCCCCGTTATTGTGGGCTTCGGTTTTTTGAAGGGTAATATTGCCGAGGCGGTCGCCGCCAATCCCGCTCTGCC
CTTCAACAGTTATGACGCCTTTTGCAAGGCCGTGGGCGAATGGGCTACCATCATGCACGCGCCCATGGCTATTATCCTCA
CCATCTTTATGCTGGGCTTCCTGACGCGCTTTTTCGGTCCTGAAAAGTCCTGGGCCGCGGGCTTCCGCGCCTGGAAATAC
TGCGTGTTCGCCGCTGTGTGCTTTCTTGTGCCGTACCTTTTGTGTGCCTGGCTGCTCGGACCGGAATTTCCCGCCATGCT
GGGCGGCCTTTTGGGCCTTGGTGTTGTGGTGTGGGGAACCAAGAAAGGTTTTTGCGTACCCAAGGACGTGTGGGAATTCG
CCCCTTCCAGCCAGTGGGACAAAGCCTGGACAGGCACAGTGCCCGCCAGCACCAAGACCGAGTTTCACGCCAGCATGAGC
CAGCTGCGCGCGTGGCTGCCGTATGTGATCATCTGCCTGCTGCTGGTTATCTCGCGCATTCCCTCCTTGGGGCTCAAGGG
CTGGTTGACCAGCCAGAAGATCAGCTTCAACAGCATTCTGGGTTTCAGCGGGGTCAATGCCAGCATTGATTACCTGTACC
TGCCCGGAACATTCTTTATCGTGGTGTCGCTGCTGACCATCATGTTGCATAAAATGCCCGGCCAGGCTGTTTCCCGTGCC
TGGAAGGAAAGCTTCCGCAAGATGAAGTCGCCGACCATTGCCCTGGTCTTCGCTGTGGCTATGGTGTCCATCTTCCGCGG
TTCGGCTACCAACCCTGCCGAAGTTCCCTCCATGCCTCTTGCCCTGGCTGAAGCTGTGGGTGCTTTTGCCGGTTCGGTAT
GGCCCATGCTTGCGGCTTTTGTGGGCGGCCTGGGAGCCTTTATCACCGGTTCCAATACGGTTTCTGACCTTATGTTTGCT
GAATTCCAGTGGAACATGGCCGGAACCCTGGAACTGCCGCGCCAGATCATCGTGGCTGCGCAGGCCGTGGGCGGCGCTAT
GGGCAACATGATCTGCGTGCATAATATCGTTGCCGCCTGCGCCGTTGTGGGGCTTTCCGGCCGTGAAGGCGAAGTGCTTC
GCCGCACGTTCTGGCCCTTCCTGCTGTACGGTCTTGTGGTGGGCATCATCTGCTGGGTGCTGGTGGTCGTCAACCCCACG
GTGTTCTAA

Upstream 100 bases:

>100_bases
CCGGGCAGCTTCGATCATTTATTTGGTTGAGTGAATAAAGAGCAGGGTGTACATAGATTTTTTAGAGTTATGAGAAACCC
GAGCTAACAAAGGAGTGGGC

Downstream 100 bases:

>100_bases
GGTATTCAAGCGTTTATTTTATAACCTACTGTTCCGGGGCGGCGGCCCAGGCGCCCTCGTCCCGGAACGTGCGACCCCGC
CTTGCATTGGCATCGCTTTG

Product: L-lactate transport protein

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSVGMLALLAVIPILVALVLMVGLRWPATRAMPLAWLVCAVSGVIGWKLDLLYLAALSLQGVVVAVGVLIIVFGAILILY
TLEESGGMETIQHGMQGVSRDRRIQAIIIGFMFAAFIEGAAGFGTPAALAAPLLLALGFPAMAAAVICLVFNSVPVTFGA
VGTPVIVGFGFLKGNIAEAVAANPALPFNSYDAFCKAVGEWATIMHAPMAIILTIFMLGFLTRFFGPEKSWAAGFRAWKY
CVFAAVCFLVPYLLCAWLLGPEFPAMLGGLLGLGVVVWGTKKGFCVPKDVWEFAPSSQWDKAWTGTVPASTKTEFHASMS
QLRAWLPYVIICLLLVISRIPSLGLKGWLTSQKISFNSILGFSGVNASIDYLYLPGTFFIVVSLLTIMLHKMPGQAVSRA
WKESFRKMKSPTIALVFAVAMVSIFRGSATNPAEVPSMPLALAEAVGAFAGSVWPMLAAFVGGLGAFITGSNTVSDLMFA
EFQWNMAGTLELPRQIIVAAQAVGGAMGNMICVHNIVAACAVVGLSGREGEVLRRTFWPFLLYGLVVGIICWVLVVVNPT
VF

Sequences:

>Translated_562_residues
MSVGMLALLAVIPILVALVLMVGLRWPATRAMPLAWLVCAVSGVIGWKLDLLYLAALSLQGVVVAVGVLIIVFGAILILY
TLEESGGMETIQHGMQGVSRDRRIQAIIIGFMFAAFIEGAAGFGTPAALAAPLLLALGFPAMAAAVICLVFNSVPVTFGA
VGTPVIVGFGFLKGNIAEAVAANPALPFNSYDAFCKAVGEWATIMHAPMAIILTIFMLGFLTRFFGPEKSWAAGFRAWKY
CVFAAVCFLVPYLLCAWLLGPEFPAMLGGLLGLGVVVWGTKKGFCVPKDVWEFAPSSQWDKAWTGTVPASTKTEFHASMS
QLRAWLPYVIICLLLVISRIPSLGLKGWLTSQKISFNSILGFSGVNASIDYLYLPGTFFIVVSLLTIMLHKMPGQAVSRA
WKESFRKMKSPTIALVFAVAMVSIFRGSATNPAEVPSMPLALAEAVGAFAGSVWPMLAAFVGGLGAFITGSNTVSDLMFA
EFQWNMAGTLELPRQIIVAAQAVGGAMGNMICVHNIVAACAVVGLSGREGEVLRRTFWPFLLYGLVVGIICWVLVVVNPT
VF
>Mature_561_residues
SVGMLALLAVIPILVALVLMVGLRWPATRAMPLAWLVCAVSGVIGWKLDLLYLAALSLQGVVVAVGVLIIVFGAILILYT
LEESGGMETIQHGMQGVSRDRRIQAIIIGFMFAAFIEGAAGFGTPAALAAPLLLALGFPAMAAAVICLVFNSVPVTFGAV
GTPVIVGFGFLKGNIAEAVAANPALPFNSYDAFCKAVGEWATIMHAPMAIILTIFMLGFLTRFFGPEKSWAAGFRAWKYC
VFAAVCFLVPYLLCAWLLGPEFPAMLGGLLGLGVVVWGTKKGFCVPKDVWEFAPSSQWDKAWTGTVPASTKTEFHASMSQ
LRAWLPYVIICLLLVISRIPSLGLKGWLTSQKISFNSILGFSGVNASIDYLYLPGTFFIVVSLLTIMLHKMPGQAVSRAW
KESFRKMKSPTIALVFAVAMVSIFRGSATNPAEVPSMPLALAEAVGAFAGSVWPMLAAFVGGLGAFITGSNTVSDLMFAE
FQWNMAGTLELPRQIIVAAQAVGGAMGNMICVHNIVAACAVVGLSGREGEVLRRTFWPFLLYGLVVGIICWVLVVVNPTV
F

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=508, Percent_Identity=28.1496062992126, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789347, Length=587, Percent_Identity=26.7461669505963, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 59893; Mature: 59762

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVGMLALLAVIPILVALVLMVGLRWPATRAMPLAWLVCAVSGVIGWKLDLLYLAALSLQ
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVVAVGVLIIVFGAILILYTLEESGGMETIQHGMQGVSRDRRIQAIIIGFMFAAFIEGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
AGFGTPAALAAPLLLALGFPAMAAAVICLVFNSVPVTFGAVGTPVIVGFGFLKGNIAEAV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AANPALPFNSYDAFCKAVGEWATIMHAPMAIILTIFMLGFLTRFFGPEKSWAAGFRAWKY
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
CVFAAVCFLVPYLLCAWLLGPEFPAMLGGLLGLGVVVWGTKKGFCVPKDVWEFAPSSQWD
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHCCCCCCCC
KAWTGTVPASTKTEFHASMSQLRAWLPYVIICLLLVISRIPSLGLKGWLTSQKISFNSIL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
GFSGVNASIDYLYLPGTFFIVVSLLTIMLHKMPGQAVSRAWKESFRKMKSPTIALVFAVA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
MVSIFRGSATNPAEVPSMPLALAEAVGAFAGSVWPMLAAFVGGLGAFITGSNTVSDLMFA
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHH
EFQWNMAGTLELPRQIIVAAQAVGGAMGNMICVHNIVAACAVVGLSGREGEVLRRTFWPF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LLYGLVVGIICWVLVVVNPTVF
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]