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The map label for this gene is hdrA [H]

Identifier: 220905388

GI number: 220905388

Start: 2561515

End: 2563785

Strand: Reverse

Name: hdrA [H]

Synonym: Ddes_2126

Alternate gene names: 220905388

Gene position: 2563785-2561515 (Counterclockwise)

Preceding gene: 220905389

Following gene: 220905387

Centisome position: 89.22

GC content: 59.67

Gene sequence:

>2271_bases
ATGTCCGGTAAGATTGGCGTCTATTTTGACCAGCAGAACATTGGCGGCGGCCTCGATGTAGAGGCGCTTGCCGCGCAGAC
CTCGGCAAAGTGGGGAGATCTCACTGCCGTGGTCAAGGTAGTTCCCGTGCTGGCATTGGCCGTGGATGAAATTCGGGCCG
ATATCGAGGCCCAGGGCCTGGACGGCGTGCTGCTGTGCGGCGCTTCCCCGCGTGTGGACGGCGAACTGTACCGTCTACCC
GTGCAGGTGGAACATGTGAACCTGCGTGAGCAGTGCGTGCAGGCCTACAAGAATCCGGACAGAACGCCCGTTGATTCTGC
CAGCGCGCCCGAACTGCTGACCCTCATGGCCCACGACTACGTGAATATGGGCGTGGTGAAACTGCAGAAGAGCGAAGCCC
CCGAAGCCGCTTCGGTAACGGGTGTGCAGCGCATTCTGGTGATCGGCGGCGGCTGGACCGGCCTTACGGCGGCCCTGGAA
GCTGCGGCCACGGGTTATGAAGTGGTGCTGATAGAAAAAGCCGAAAGGCTCGGCGGCGCTGCCAACAATATCCCCATGGC
TTCTCCCCTGGTTTCTCCCTGGACGGACAAGCAGCCCACAAATCTTGCGGCCAAGGTCAGTGAAGTTACGGGCAATCCCA
AGATCAAGGTCCACATGAATTCCCGCATGGAAAAGCTGGAAGGCCAGCCCGGTGAATTCAAGGCCGTTATTGCTACGGCT
TCCGGCCCTGTGGAAGTGGAAGTGGGCGCGGTGGTGCTGGCTACGGGCTGGGTTGCCCTTGACCAGAAATACCTGGCTCC
CATGGGTCTTGGCAAAAGCCCCATGGTGGTGGATGCCGCCACGTTCGGTAAAATGCTGGTGGCCGACCAGGTGAAGGCCA
ACCGCATCGCTTTTGTGCTTGATACCACGATGGCCGAGCAGGCCGTGGCCCAGGCTGCCGGGGAAAATGCGGCCGCCGGA
GATGAAGAGCCCGCCGAGGCCGCTGCTGCCGATACTGAGGAAGGGGAAGAGGTTTTTGTGAAAGAAGACCTCGAAAGCCT
TCGGCACCTGTCCTACTCCAACGCTGTCAACAGCGTGGGTATGCTGCGCCTTGCCAACACGGTCTGTGAGAAGACCAATG
ATGCCTGCCAGGCCTTTATCCTGTACAAGGATATGACCGTTCCCGGCATTCTCGAACGCTTCTACAAAAAAATGCAGGAG
CGCCTGGGCGTCATGATGACAAAGGCCGATGTGACCGGCATCCGCGAAGCGGGCGGCCACATGGTTGTGGAGTGCAAAAA
CACCCTGCTCGGCATGGACTTTGACCTTGATGTGGACATGGTTGTTCTGCCCACGGGCCTTGTGCCCACTACGGCCAAGG
ACGTGACCATCCACTTTGACTACCGCCAGGGGCCGGACTTTCCGGACTTGCAGCTGTTTGACGGCTTTGCCGACTCAAAC
TATATCTGCTTCCCCTACGAAACGCGCCGCACCGGCGTGTATGCGGCTGGCTGCGTGCGTCAGCCCCTGACCATGGACGC
CTGCGAAGAAGACGCCAAGGGCGCGGTGCTCAAGGCCGTGCAGTGCATCGAGGCATCCAGCCACGGTGTGTCTGTGCATC
CGCGTTCGGGGGACCTTTCCTACCCCCTGTTCAATATGGTGCGCTGCACCCAGTGCAAACGCTGCACGGAAGAATGCCCC
TTCGGCGCTCTGGACGACGACGAAAAGGGAACTCCCCGGCTCAATCCCACGCGCTGCCGCCGCTGCGGTACCTGTTTCGG
CGCATGCCCCGAGCGCGTCATCTCCTTCGCCAACTACAATATTGACCAGATTGGCTCCATGATCCGTGAAGTGCAGGTGC
CCAAGGACTTCAAGAAAGAAGGCCCCCGTGTGCTCATTCTGGCCTGCGAAAACGACGCCTATCCTGCCCTTGATATGGCC
GGTGAGCGCCACAAGCCCTGGAGCCCCTATTGCCGCATCATTCCCGTACGCTGCCTTGGTTCGGTCAACGCCATCTGGGT
GTCTGACGCCATGAGCAAAGGCTATGACGGCGTGATGCTGCTGGGCTGCAAGTATGGCGATGACTACCAGTGCCACTTTG
TGAAGGGTTCGGAAATCTGCGCCAAGCGTAAGGAAAATATTGCCGAGACGCTCAACCGTCTGGGCGTGGAGCCTGAGCGT
GTGGAACTGCTTGAAGTGGCCATTGACGAGTACGACAAGGTTCCCGTCATAATTGACGGCTTTGTGGATCGCATCGTGGC
CATGGGCCCCAACCCGTTCAAGGGCATGTAG

Upstream 100 bases:

>100_bases
CCGGTTGCGCGCGCATGCCCCTCGATGTGATGCGCTCGGCTCAGTCCGGTACAGCCGCCGCCCTGAAGGCGGTACAAACG
GTGAAAGGGAGGTAGGCGGC

Downstream 100 bases:

>100_bases
GAGGAAGGCAGCAATGGCACAAATTACCATCAAACCTGATCTGGAGTTTGTCAGGGCGCTGGAAGAGGCGGGGGGCGATT
CCCTCAAGAAGTGTTACCAG

Product: methyl-viologen-reducing hydrogenase delta subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MSGKIGVYFDQQNIGGGLDVEALAAQTSAKWGDLTAVVKVVPVLALAVDEIRADIEAQGLDGVLLCGASPRVDGELYRLP
VQVEHVNLREQCVQAYKNPDRTPVDSASAPELLTLMAHDYVNMGVVKLQKSEAPEAASVTGVQRILVIGGGWTGLTAALE
AAATGYEVVLIEKAERLGGAANNIPMASPLVSPWTDKQPTNLAAKVSEVTGNPKIKVHMNSRMEKLEGQPGEFKAVIATA
SGPVEVEVGAVVLATGWVALDQKYLAPMGLGKSPMVVDAATFGKMLVADQVKANRIAFVLDTTMAEQAVAQAAGENAAAG
DEEPAEAAAADTEEGEEVFVKEDLESLRHLSYSNAVNSVGMLRLANTVCEKTNDACQAFILYKDMTVPGILERFYKKMQE
RLGVMMTKADVTGIREAGGHMVVECKNTLLGMDFDLDVDMVVLPTGLVPTTAKDVTIHFDYRQGPDFPDLQLFDGFADSN
YICFPYETRRTGVYAAGCVRQPLTMDACEEDAKGAVLKAVQCIEASSHGVSVHPRSGDLSYPLFNMVRCTQCKRCTEECP
FGALDDDEKGTPRLNPTRCRRCGTCFGACPERVISFANYNIDQIGSMIREVQVPKDFKKEGPRVLILACENDAYPALDMA
GERHKPWSPYCRIIPVRCLGSVNAIWVSDAMSKGYDGVMLLGCKYGDDYQCHFVKGSEICAKRKENIAETLNRLGVEPER
VELLEVAIDEYDKVPVIIDGFVDRIVAMGPNPFKGM

Sequences:

>Translated_756_residues
MSGKIGVYFDQQNIGGGLDVEALAAQTSAKWGDLTAVVKVVPVLALAVDEIRADIEAQGLDGVLLCGASPRVDGELYRLP
VQVEHVNLREQCVQAYKNPDRTPVDSASAPELLTLMAHDYVNMGVVKLQKSEAPEAASVTGVQRILVIGGGWTGLTAALE
AAATGYEVVLIEKAERLGGAANNIPMASPLVSPWTDKQPTNLAAKVSEVTGNPKIKVHMNSRMEKLEGQPGEFKAVIATA
SGPVEVEVGAVVLATGWVALDQKYLAPMGLGKSPMVVDAATFGKMLVADQVKANRIAFVLDTTMAEQAVAQAAGENAAAG
DEEPAEAAAADTEEGEEVFVKEDLESLRHLSYSNAVNSVGMLRLANTVCEKTNDACQAFILYKDMTVPGILERFYKKMQE
RLGVMMTKADVTGIREAGGHMVVECKNTLLGMDFDLDVDMVVLPTGLVPTTAKDVTIHFDYRQGPDFPDLQLFDGFADSN
YICFPYETRRTGVYAAGCVRQPLTMDACEEDAKGAVLKAVQCIEASSHGVSVHPRSGDLSYPLFNMVRCTQCKRCTEECP
FGALDDDEKGTPRLNPTRCRRCGTCFGACPERVISFANYNIDQIGSMIREVQVPKDFKKEGPRVLILACENDAYPALDMA
GERHKPWSPYCRIIPVRCLGSVNAIWVSDAMSKGYDGVMLLGCKYGDDYQCHFVKGSEICAKRKENIAETLNRLGVEPER
VELLEVAIDEYDKVPVIIDGFVDRIVAMGPNPFKGM
>Mature_755_residues
SGKIGVYFDQQNIGGGLDVEALAAQTSAKWGDLTAVVKVVPVLALAVDEIRADIEAQGLDGVLLCGASPRVDGELYRLPV
QVEHVNLREQCVQAYKNPDRTPVDSASAPELLTLMAHDYVNMGVVKLQKSEAPEAASVTGVQRILVIGGGWTGLTAALEA
AATGYEVVLIEKAERLGGAANNIPMASPLVSPWTDKQPTNLAAKVSEVTGNPKIKVHMNSRMEKLEGQPGEFKAVIATAS
GPVEVEVGAVVLATGWVALDQKYLAPMGLGKSPMVVDAATFGKMLVADQVKANRIAFVLDTTMAEQAVAQAAGENAAAGD
EEPAEAAAADTEEGEEVFVKEDLESLRHLSYSNAVNSVGMLRLANTVCEKTNDACQAFILYKDMTVPGILERFYKKMQER
LGVMMTKADVTGIREAGGHMVVECKNTLLGMDFDLDVDMVVLPTGLVPTTAKDVTIHFDYRQGPDFPDLQLFDGFADSNY
ICFPYETRRTGVYAAGCVRQPLTMDACEEDAKGAVLKAVQCIEASSHGVSVHPRSGDLSYPLFNMVRCTQCKRCTEECPF
GALDDDEKGTPRLNPTRCRRCGTCFGACPERVISFANYNIDQIGSMIREVQVPKDFKKEGPRVLILACENDAYPALDMAG
ERHKPWSPYCRIIPVRCLGSVNAIWVSDAMSKGYDGVMLLGCKYGDDYQCHFVKGSEICAKRKENIAETLNRLGVEPERV
ELLEVAIDEYDKVPVIIDGFVDRIVAMGPNPFKGM

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR003813
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4; PF02662 FlpD [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 81831; Mature: 81699

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKIGVYFDQQNIGGGLDVEALAAQTSAKWGDLTAVVKVVPVLALAVDEIRADIEAQGL
CCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGVLLCGASPRVDGELYRLPVQVEHVNLREQCVQAYKNPDRTPVDSASAPELLTLMAHDY
CEEEEECCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
VNMGVVKLQKSEAPEAASVTGVQRILVIGGGWTGLTAALEAAATGYEVVLIEKAERLGGA
HCCCEEEEECCCCCCCHHHHCEEEEEEEECCHHHHHHHHHHHCCCEEEEEEEEHHHCCCC
ANNIPMASPLVSPWTDKQPTNLAAKVSEVTGNPKIKVHMNSRMEKLEGQPGEFKAVIATA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHCCCCCCEEEEEEEC
SGPVEVEVGAVVLATGWVALDQKYLAPMGLGKSPMVVDAATFGKMLVADQVKANRIAFVL
CCCEEEEECEEEEEECHHHHCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEE
DTTMAEQAVAQAAGENAAAGDEEPAEAAAADTEEGEEVFVKEDLESLRHLSYSNAVNSVG
EHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
MLRLANTVCEKTNDACQAFILYKDMTVPGILERFYKKMQERLGVMMTKADVTGIREAGGH
HHHHHHHHHHCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHCEEEEEHHHHHHHHCCCE
MVVECKNTLLGMDFDLDVDMVVLPTGLVPTTAKDVTIHFDYRQGPDFPDLQLFDGFADSN
EEEEECCCEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCC
YICFPYETRRTGVYAAGCVRQPLTMDACEEDAKGAVLKAVQCIEASSHGVSVHPRSGDLS
EEEECCCCCCCCEEEEHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCC
YPLFNMVRCTQCKRCTEECPFGALDDDEKGTPRLNPTRCRRCGTCFGACPERVISFANYN
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCHHHHHHHHCCC
IDQIGSMIREVQVPKDFKKEGPRVLILACENDAYPALDMAGERHKPWSPYCRIIPVRCLG
HHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCCCCCCCEEEEEECCC
SVNAIWVSDAMSKGYDGVMLLGCKYGDDYQCHFVKGSEICAKRKENIAETLNRLGVEPER
CCCEEEEEHHHHCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHH
VELLEVAIDEYDKVPVIIDGFVDRIVAMGPNPFKGM
HHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SGKIGVYFDQQNIGGGLDVEALAAQTSAKWGDLTAVVKVVPVLALAVDEIRADIEAQGL
CCCEEEEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGVLLCGASPRVDGELYRLPVQVEHVNLREQCVQAYKNPDRTPVDSASAPELLTLMAHDY
CEEEEECCCCCCCCEEEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
VNMGVVKLQKSEAPEAASVTGVQRILVIGGGWTGLTAALEAAATGYEVVLIEKAERLGGA
HCCCEEEEECCCCCCCHHHHCEEEEEEEECCHHHHHHHHHHHCCCEEEEEEEEHHHCCCC
ANNIPMASPLVSPWTDKQPTNLAAKVSEVTGNPKIKVHMNSRMEKLEGQPGEFKAVIATA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHCCCCCCEEEEEEEC
SGPVEVEVGAVVLATGWVALDQKYLAPMGLGKSPMVVDAATFGKMLVADQVKANRIAFVL
CCCEEEEECEEEEEECHHHHCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEE
DTTMAEQAVAQAAGENAAAGDEEPAEAAAADTEEGEEVFVKEDLESLRHLSYSNAVNSVG
EHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
MLRLANTVCEKTNDACQAFILYKDMTVPGILERFYKKMQERLGVMMTKADVTGIREAGGH
HHHHHHHHHHCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHCEEEEEHHHHHHHHCCCE
MVVECKNTLLGMDFDLDVDMVVLPTGLVPTTAKDVTIHFDYRQGPDFPDLQLFDGFADSN
EEEEECCCEECCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCC
YICFPYETRRTGVYAAGCVRQPLTMDACEEDAKGAVLKAVQCIEASSHGVSVHPRSGDLS
EEEECCCCCCCCEEEEHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCC
YPLFNMVRCTQCKRCTEECPFGALDDDEKGTPRLNPTRCRRCGTCFGACPERVISFANYN
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCHHHHHHHHCCC
IDQIGSMIREVQVPKDFKKEGPRVLILACENDAYPALDMAGERHKPWSPYCRIIPVRCLG
HHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCCCCCCCEEEEEECCC
SVNAIWVSDAMSKGYDGVMLLGCKYGDDYQCHFVKGSEICAKRKENIAETLNRLGVEPER
CCCEEEEEHHHHCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHH
VELLEVAIDEYDKVPVIIDGFVDRIVAMGPNPFKGM
HHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]