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The map label for this gene is hdrC [H]

Identifier: 220905387

GI number: 220905387

Start: 2560320

End: 2561501

Strand: Reverse

Name: hdrC [H]

Synonym: Ddes_2125

Alternate gene names: 220905387

Gene position: 2561501-2560320 (Counterclockwise)

Preceding gene: 220905388

Following gene: 220905386

Centisome position: 89.14

GC content: 58.63

Gene sequence:

>1182_bases
ATGGCACAAATTACCATCAAACCTGATCTGGAGTTTGTCAGGGCGCTGGAAGAGGCGGGGGGCGATTCCCTCAAGAAGTG
TTACCAGTGCGCCACATGCTCGGTGGCATGCCCACTGTCTCCTGCCAATGCGCCTTATCCGCGCAAGGAAATGGTGTGGG
CCTCCTGGGGCCTCAAGGACAAACTGCGTGGAGATATCGACCTGTGGCTTTGCCACAACTGCGGCAACTGCTCTGACCTG
TGCCCGCGCGGAGCCAAACCCGCTGATCTTATGGGCGCGGCGCGTAACGTCATTTACAAGGACCTGACCGAACCCACGGT
AGTGGGCAAGTGGATGAGCAAACCTTCGGGCCTGCCCATTCTCTTCGGCATTCCTGCTGTCATATGGCTTGTGGTGTGGT
GGATCCGCGCCGGCTTCAACGGTGGCCAGTGGTTCCCCCGCGCTGCCGATGGCCGTATTGTGTTCGGCCAGATATTCTAC
GGCGATTATACCATCGACCCCATCTTCATACTGACGTTCTTTGGCGCACTCTTCATTCTGGCGCGCGGCGTCATGAAACT
GTGGGCGCTCTTCAGGCCTGAAGGCACAACGACCGTCATCGGCAAAACAAAATGCTGGATATGGCATTTGTGGGACGTGC
TGTGGGATGAAGTCATCACGCACCGCAAGTTCGACGACTGCGAAACCGGCCCCGCCACGGGCAAGGATACCCCCAGCCGT
AAGTACGGACACTTTCTGCTGGTGTGGAGCTTTGTGATCCTGGCCTGCGTAACCGCCATAGTGGCTTTCGCCCACTGGGG
CGGCAAGGTGATACCCATCATCCACTTTGAAACGCCCATGCCGTTGACCTTCCCGGTGAAAATTCTTGCCAACATCGGCG
CGCTCATGCTGCTGCTGGGTCTGGGCTTTCTTACGGTGCGCCGTCTGCGCCTGAACCCCAGGTTCCAGGGATCCAACTGG
TACGACTGGTACCTGCTGGGCATCATCTGGCTGGTGGCAGTTACCGGTGTGCTGGCACAGTGCTTCCGCCTGGCGGACAC
CATTGTGCCCGCCTTCCTGGTGTACTACCTGCACCTGGTTTTTGTGTGGATGCTCTTTGCCTATCTGCCCTGGTCCAAAC
TCGGGCACTTTGTCTACCGCACGGCGGCCCTGCTGTACGCCCGCATGTACGGCAGAAGCTAG

Upstream 100 bases:

>100_bases
GACGAGTACGACAAGGTTCCCGTCATAATTGACGGCTTTGTGGATCGCATCGTGGCCATGGGCCCCAACCCGTTCAAGGG
CATGTAGGAGGAAGGCAGCA

Downstream 100 bases:

>100_bases
TTGGCGCGGCGTTCCCGGCGGTCAGCCGCCGGGAACGCCGACAGAGTGTGCACTGTTGGCATTAAAGTTTTATTGAATAA
AATTACGATCTCCGAGGAGG

Product: heterodisulfide reductase, transmembrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MAQITIKPDLEFVRALEEAGGDSLKKCYQCATCSVACPLSPANAPYPRKEMVWASWGLKDKLRGDIDLWLCHNCGNCSDL
CPRGAKPADLMGAARNVIYKDLTEPTVVGKWMSKPSGLPILFGIPAVIWLVVWWIRAGFNGGQWFPRAADGRIVFGQIFY
GDYTIDPIFILTFFGALFILARGVMKLWALFRPEGTTTVIGKTKCWIWHLWDVLWDEVITHRKFDDCETGPATGKDTPSR
KYGHFLLVWSFVILACVTAIVAFAHWGGKVIPIIHFETPMPLTFPVKILANIGALMLLLGLGFLTVRRLRLNPRFQGSNW
YDWYLLGIIWLVAVTGVLAQCFRLADTIVPAFLVYYLHLVFVWMLFAYLPWSKLGHFVYRTAALLYARMYGRS

Sequences:

>Translated_393_residues
MAQITIKPDLEFVRALEEAGGDSLKKCYQCATCSVACPLSPANAPYPRKEMVWASWGLKDKLRGDIDLWLCHNCGNCSDL
CPRGAKPADLMGAARNVIYKDLTEPTVVGKWMSKPSGLPILFGIPAVIWLVVWWIRAGFNGGQWFPRAADGRIVFGQIFY
GDYTIDPIFILTFFGALFILARGVMKLWALFRPEGTTTVIGKTKCWIWHLWDVLWDEVITHRKFDDCETGPATGKDTPSR
KYGHFLLVWSFVILACVTAIVAFAHWGGKVIPIIHFETPMPLTFPVKILANIGALMLLLGLGFLTVRRLRLNPRFQGSNW
YDWYLLGIIWLVAVTGVLAQCFRLADTIVPAFLVYYLHLVFVWMLFAYLPWSKLGHFVYRTAALLYARMYGRS
>Mature_392_residues
AQITIKPDLEFVRALEEAGGDSLKKCYQCATCSVACPLSPANAPYPRKEMVWASWGLKDKLRGDIDLWLCHNCGNCSDLC
PRGAKPADLMGAARNVIYKDLTEPTVVGKWMSKPSGLPILFGIPAVIWLVVWWIRAGFNGGQWFPRAADGRIVFGQIFYG
DYTIDPIFILTFFGALFILARGVMKLWALFRPEGTTTVIGKTKCWIWHLWDVLWDEVITHRKFDDCETGPATGKDTPSRK
YGHFLLVWSFVILACVTAIVAFAHWGGKVIPIIHFETPMPLTFPVKILANIGALMLLLGLGFLTVRRLRLNPRFQGSNWY
DWYLLGIIWLVAVTGVLAQCFRLADTIVPAFLVYYLHLVFVWMLFAYLPWSKLGHFVYRTAALLYARMYGRS

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrC may carry electrons from hydrogenase to hdrA [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017680
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 44499; Mature: 44368

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQITIKPDLEFVRALEEAGGDSLKKCYQCATCSVACPLSPANAPYPRKEMVWASWGLKD
CCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHEEECCCCCH
KLRGDIDLWLCHNCGNCSDLCPRGAKPADLMGAARNVIYKDLTEPTVVGKWMSKPSGLPI
HCCCCEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEE
LFGIPAVIWLVVWWIRAGFNGGQWFPRAADGRIVFGQIFYGDYTIDPIFILTFFGALFIL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHH
ARGVMKLWALFRPEGTTTVIGKTKCWIWHLWDVLWDEVITHRKFDDCETGPATGKDTPSR
HHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KYGHFLLVWSFVILACVTAIVAFAHWGGKVIPIIHFETPMPLTFPVKILANIGALMLLLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LGFLTVRRLRLNPRFQGSNWYDWYLLGIIWLVAVTGVLAQCFRLADTIVPAFLVYYLHLV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVWMLFAYLPWSKLGHFVYRTAALLYARMYGRS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQITIKPDLEFVRALEEAGGDSLKKCYQCATCSVACPLSPANAPYPRKEMVWASWGLKD
CEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHEEECCCCCH
KLRGDIDLWLCHNCGNCSDLCPRGAKPADLMGAARNVIYKDLTEPTVVGKWMSKPSGLPI
HCCCCEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEE
LFGIPAVIWLVVWWIRAGFNGGQWFPRAADGRIVFGQIFYGDYTIDPIFILTFFGALFIL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHH
ARGVMKLWALFRPEGTTTVIGKTKCWIWHLWDVLWDEVITHRKFDDCETGPATGKDTPSR
HHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KYGHFLLVWSFVILACVTAIVAFAHWGGKVIPIIHFETPMPLTFPVKILANIGALMLLLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LGFLTVRRLRLNPRFQGSNWYDWYLLGIIWLVAVTGVLAQCFRLADTIVPAFLVYYLHLV
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVWMLFAYLPWSKLGHFVYRTAALLYARMYGRS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]