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The map label for this gene is vat [H]

Identifier: 220905308

GI number: 220905308

Start: 2459690

End: 2460415

Strand: Reverse

Name: vat [H]

Synonym: Ddes_2046

Alternate gene names: 220905308

Gene position: 2460415-2459690 (Counterclockwise)

Preceding gene: 220905309

Following gene: 220905307

Centisome position: 85.63

GC content: 67.36

Gene sequence:

>726_bases
ATGGCTGCGCTCGAAAAAACGGGCATGACGCAAGAAGCGGGGCAGGCCGGCCGGGCCGGCCCTGCTGTACCCTCCGAATC
CGCCGGTACCGCAGCGCCGGAGCATGGCGCTCCGGGCTGGTGCCGCCGTCTCGGGGCTGCGCTGGAAGAGCTGTGGATAG
CCCTGCTCGGCTGGATACCCACGCCCGTGGGGCTGGCCCTGCGGCTTGCAGGCTGGCGCTGGCTTTTTGCCCGTTGCGGC
TCGGTGCGCTTCAGCACGGGGCTGAGCCTCGCAGGCTGCCGGGGTATGTGCCTGGGCAGCAACGTACGCCTTGGGCGCGG
CTGCTTTATCACTGCCACAGACGGCGAACTGGTGCTGCACGACAACGTGGCCCTGTCGCCCTATGTGCATGTGGGGGCCG
ATGCGGGCCGCATTGAAATCGGCGCGCACACGGCCGTGGGACCGGGAACGGTCATACGCGCGGCCAATCACTGCATAGCC
CGTCAGGATGTGCCCATGATGCATCAGGGGCACGTGCCGGGCGAGATCATTATTGAAGAAGACGTATGGATAGGGGCCAA
TTGCGTCATTACGCCCGATGTGCGCATCGGGCGCGGTGCGGTGGTGGGAGCGGGGGCCGTGGTTACCCGCAATGTGGCCC
CCTTCAGCATAGTGGGCGGGGTTCCGGCCCGTGTCATCGGCATGCGCGGGCAGAGCGGACAACCTGTGGGCGGCCAGATC
GCGTAA

Upstream 100 bases:

>100_bases
CGGCCAGCCGCACCTGGAGCGTGGACACGCCCGAGGACCTCGTGCGCGTCTGCCGCCTTATGGAAGGTGACGACCTTATG
AAGGAATACAGCAAATAATC

Downstream 100 bases:

>100_bases
GGGCTGTTGCCGCCAAGTCCCTTTGTGCGGGCGCTTCGTCAAAAGATATTTTTGGCCGTTAAGGCATGGCACAAGTACCT
TTCTATAAAAAAGCCCTATT

Product: transferase hexapeptide repeat containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MAALEKTGMTQEAGQAGRAGPAVPSESAGTAAPEHGAPGWCRRLGAALEELWIALLGWIPTPVGLALRLAGWRWLFARCG
SVRFSTGLSLAGCRGMCLGSNVRLGRGCFITATDGELVLHDNVALSPYVHVGADAGRIEIGAHTAVGPGTVIRAANHCIA
RQDVPMMHQGHVPGEIIIEEDVWIGANCVITPDVRIGRGAVVGAGAVVTRNVAPFSIVGGVPARVIGMRGQSGQPVGGQI
A

Sequences:

>Translated_241_residues
MAALEKTGMTQEAGQAGRAGPAVPSESAGTAAPEHGAPGWCRRLGAALEELWIALLGWIPTPVGLALRLAGWRWLFARCG
SVRFSTGLSLAGCRGMCLGSNVRLGRGCFITATDGELVLHDNVALSPYVHVGADAGRIEIGAHTAVGPGTVIRAANHCIA
RQDVPMMHQGHVPGEIIIEEDVWIGANCVITPDVRIGRGAVVGAGAVVTRNVAPFSIVGGVPARVIGMRGQSGQPVGGQI
A
>Mature_240_residues
AALEKTGMTQEAGQAGRAGPAVPSESAGTAAPEHGAPGWCRRLGAALEELWIALLGWIPTPVGLALRLAGWRWLFARCGS
VRFSTGLSLAGCRGMCLGSNVRLGRGCFITATDGELVLHDNVALSPYVHVGADAGRIEIGAHTAVGPGTVIRAANHCIAR
QDVPMMHQGHVPGEIIIEEDVWIGANCVITPDVRIGRGAVVGAGAVVTRNVAPFSIVGGVPARVIGMRGQSGQPVGGQIA

Specific function: Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1788345, Length=170, Percent_Identity=27.6470588235294, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 24757; Mature: 24626

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALEKTGMTQEAGQAGRAGPAVPSESAGTAAPEHGAPGWCRRLGAALEELWIALLGWIP
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
TPVGLALRLAGWRWLFARCGSVRFSTGLSLAGCRGMCLGSNVRLGRGCFITATDGELVLH
CCHHHHHHHHHHHEEHHHCCCEEEECCCCCCCCCCEEECCCEEECCCEEEEECCCCEEEE
DNVALSPYVHVGADAGRIEIGAHTAVGPGTVIRAANHCIARQDVPMMHQGHVPGEIIIEE
CCEEECCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEC
DVWIGANCVITPDVRIGRGAVVGAGAVVTRNVAPFSIVGGVPARVIGMRGQSGQPVGGQI
CEEECCCEEECCCCEECCCEEEECCEEEECCCCCEEEECCCCEEEEEECCCCCCCCCCCC
A
C
>Mature Secondary Structure 
AALEKTGMTQEAGQAGRAGPAVPSESAGTAAPEHGAPGWCRRLGAALEELWIALLGWIP
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
TPVGLALRLAGWRWLFARCGSVRFSTGLSLAGCRGMCLGSNVRLGRGCFITATDGELVLH
CCHHHHHHHHHHHEEHHHCCCEEEECCCCCCCCCCEEECCCEEECCCEEEEECCCCEEEE
DNVALSPYVHVGADAGRIEIGAHTAVGPGTVIRAANHCIARQDVPMMHQGHVPGEIIIEE
CCEEECCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEC
DVWIGANCVITPDVRIGRGAVVGAGAVVTRNVAPFSIVGGVPARVIGMRGQSGQPVGGQI
CEEECCCEEECCCCEECCCEEEECCEEEECCCCCEEEECCCCEEEEEECCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8344533; 3149758 [H]