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The map label for this gene is speE [H]

Identifier: 220905292

GI number: 220905292

Start: 2442277

End: 2443809

Strand: Reverse

Name: speE [H]

Synonym: Ddes_2030

Alternate gene names: 220905292

Gene position: 2443809-2442277 (Counterclockwise)

Preceding gene: 220905293

Following gene: 220905291

Centisome position: 85.05

GC content: 62.23

Gene sequence:

>1533_bases
ATGCTGGAACTGACGGTTTTTTTTAGCGGCGCCCTGGTCATGGTGCTGGAAATGGTGGGCGCGCGCGTGCTGGCCCCTTA
TGTGGGCACATCAGCCATTGTCTGGACCAGCCTCATCGGCGTGGTGCTCGCCTGTCTGGCGCTGGGGGCCTGGGCTGGCG
GCCGTATGGCCGACAGGCATCTTTCCCGCAGGGGGCTTGCCCTTGCCCTGGCCGGAGCCGGGGCGGGCAGCGCGCTTACG
GCCCTGTGTCATCCGCTGGTGGGCCAGTGGGTGACCGAGGGCATCGGCAATCTGTATGTGGCCGCTGTTGCCGCCGCTGT
GGGAATCTTCGCCTTGCCCGCCTTTTTTTTCGGCATGGTCAGCCCCTACGCCATCCGTTTGCGCATCGGCAGCCTGGACA
CGTCCGGGGCCACGGTAGGGCGGTTGTACGCCCTTTCCACGGCGGGCAGCATTCTGGGAACCTTTCTGGGCGGGTTTGTG
CTCATATCGTTTTTTGGCAGCTCGTCCATCTTGTGGGGGGTGGCTGTCTGCATGCTGGCCCTTTCATTGTGCAATGCGCC
GGGCGGGGCCAAGGGCAGGGCAGCCCTGCTGGCCCTCTGCATTTTGGGAACCGCGATCAACGGCATGTACGGAAACTGGC
GCGAAGACAGAGGCAGCATGCATCTTGTGGAAAGCCCCTATAACAGCATCCGCGTTTACGAAGGCACGGACTGGGGCGAG
GGCGGCCGCGCCGTGCGGCTCATGGCTACGGACCCGGGGTACAGCCAGTCGGGCATGTATCTTGACGCACCGGACGAGCT
TTATTTTCAGTATACGCGGTTTTATGCTCTGGGTCCCTACTTTGTGCCTCATGCCCGCTCCATACTGATGCTGGGCGGCG
GGGGCTATTCCGTGCCCAAATGGATTCTGGCGGGCAAATCGGCCCTGGCTGCCCCCGAAGATGTGCGCATGACTGTTGTG
GAAATAGATCCGGCCATGACTGACGTGGCCCGGCGCTGGTTTGCCCTGGGCGACGACGTGCGCCTTTCGGTACGCCACGA
AGACGCCCGTGCCTTTCTGAACAGGCAGGACGGGCGTTTTGACCTGGTTTTTGTGGATGTGTTCAACTCGCACTATGCGG
TTCCCTTTCAGATGGGAACGGTAGAGGCGGCGCGGGCTTTGCGGCGGGCCGTGGCCCCGGGCGGCGCCGTGCTCATGAAC
GTCATTTCTGCCGTGGAAGGAGAGGACGGCCGCCTGTTTCAGAGTATTTTCAAGGCATTGTCCACATCATTCGCAGAGGT
GCAGGTATACTGCGTGTCGCGTCCCGACAGGCCCGGCGAGGTGCAGAACCTTATGGTGGCGGCTTTTCCTGAAAAAAGAG
ACAGGGCCGCACCGCTGGCCGCTGGGAGCACACAGGTACAGCTCACGGAGCAGAAGCCTGTGGAAATGATGCTGGCTACA
AGGTACACAGGGCCGCTGGATTTTGCTACACTGCCCCTGACCGACGATTTTGCCCCGGTGGAGCGTTACGCCCTCATGCT
GCTGCGGCAGTGA

Upstream 100 bases:

>100_bases
GCGGTTCTGCACATTGCTGCAGGAGGTCAGACGTTCTGTTTCTGAGACAGCATTTTTTCATTGGGTCTTGTCCCGGAGCA
AGAAGCCGGAAAGGAGTGCC

Downstream 100 bases:

>100_bases
TCCCTGCTGCTGTGCCTTCCGTGTCGCCGTTTTTCTGCGGGGAGCGCTCCGCACGGGGTTTTGTGATGCTGCGCCGCAGT
CTGGCCCCCTTGCGGGATGG

Product: Spermine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MLELTVFFSGALVMVLEMVGARVLAPYVGTSAIVWTSLIGVVLACLALGAWAGGRMADRHLSRRGLALALAGAGAGSALT
ALCHPLVGQWVTEGIGNLYVAAVAAAVGIFALPAFFFGMVSPYAIRLRIGSLDTSGATVGRLYALSTAGSILGTFLGGFV
LISFFGSSSILWGVAVCMLALSLCNAPGGAKGRAALLALCILGTAINGMYGNWREDRGSMHLVESPYNSIRVYEGTDWGE
GGRAVRLMATDPGYSQSGMYLDAPDELYFQYTRFYALGPYFVPHARSILMLGGGGYSVPKWILAGKSALAAPEDVRMTVV
EIDPAMTDVARRWFALGDDVRLSVRHEDARAFLNRQDGRFDLVFVDVFNSHYAVPFQMGTVEAARALRRAVAPGGAVLMN
VISAVEGEDGRLFQSIFKALSTSFAEVQVYCVSRPDRPGEVQNLMVAAFPEKRDRAAPLAAGSTQVQLTEQKPVEMMLAT
RYTGPLDFATLPLTDDFAPVERYALMLLRQ

Sequences:

>Translated_510_residues
MLELTVFFSGALVMVLEMVGARVLAPYVGTSAIVWTSLIGVVLACLALGAWAGGRMADRHLSRRGLALALAGAGAGSALT
ALCHPLVGQWVTEGIGNLYVAAVAAAVGIFALPAFFFGMVSPYAIRLRIGSLDTSGATVGRLYALSTAGSILGTFLGGFV
LISFFGSSSILWGVAVCMLALSLCNAPGGAKGRAALLALCILGTAINGMYGNWREDRGSMHLVESPYNSIRVYEGTDWGE
GGRAVRLMATDPGYSQSGMYLDAPDELYFQYTRFYALGPYFVPHARSILMLGGGGYSVPKWILAGKSALAAPEDVRMTVV
EIDPAMTDVARRWFALGDDVRLSVRHEDARAFLNRQDGRFDLVFVDVFNSHYAVPFQMGTVEAARALRRAVAPGGAVLMN
VISAVEGEDGRLFQSIFKALSTSFAEVQVYCVSRPDRPGEVQNLMVAAFPEKRDRAAPLAAGSTQVQLTEQKPVEMMLAT
RYTGPLDFATLPLTDDFAPVERYALMLLRQ
>Mature_510_residues
MLELTVFFSGALVMVLEMVGARVLAPYVGTSAIVWTSLIGVVLACLALGAWAGGRMADRHLSRRGLALALAGAGAGSALT
ALCHPLVGQWVTEGIGNLYVAAVAAAVGIFALPAFFFGMVSPYAIRLRIGSLDTSGATVGRLYALSTAGSILGTFLGGFV
LISFFGSSSILWGVAVCMLALSLCNAPGGAKGRAALLALCILGTAINGMYGNWREDRGSMHLVESPYNSIRVYEGTDWGE
GGRAVRLMATDPGYSQSGMYLDAPDELYFQYTRFYALGPYFVPHARSILMLGGGGYSVPKWILAGKSALAAPEDVRMTVV
EIDPAMTDVARRWFALGDDVRLSVRHEDARAFLNRQDGRFDLVFVDVFNSHYAVPFQMGTVEAARALRRAVAPGGAVLMN
VISAVEGEDGRLFQSIFKALSTSFAEVQVYCVSRPDRPGEVQNLMVAAFPEKRDRAAPLAAGSTQVQLTEQKPVEMMLAT
RYTGPLDFATLPLTDDFAPVERYALMLLRQ

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 54590; Mature: 54590

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELTVFFSGALVMVLEMVGARVLAPYVGTSAIVWTSLIGVVLACLALGAWAGGRMADRH
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LSRRGLALALAGAGAGSALTALCHPLVGQWVTEGIGNLYVAAVAAAVGIFALPAFFFGMV
HHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPYAIRLRIGSLDTSGATVGRLYALSTAGSILGTFLGGFVLISFFGSSSILWGVAVCMLA
CCEEEEEEEECCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LSLCNAPGGAKGRAALLALCILGTAINGMYGNWREDRGSMHLVESPYNSIRVYEGTDWGE
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCC
GGRAVRLMATDPGYSQSGMYLDAPDELYFQYTRFYALGPYFVPHARSILMLGGGGYSVPK
CCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHEECCEECCCCCEEEEECCCCCCCCH
WILAGKSALAAPEDVRMTVVEIDPAMTDVARRWFALGDDVRLSVRHEDARAFLNRQDGRF
HHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCCCCCCE
DLVFVDVFNSHYAVPFQMGTVEAARALRRAVAPGGAVLMNVISAVEGEDGRLFQSIFKAL
EEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
STSFAEVQVYCVSRPDRPGEVQNLMVAAFPEKRDRAAPLAAGSTQVQLTEQKPVEMMLAT
CCCCEEEEEEEECCCCCCCHHHHEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
RYTGPLDFATLPLTDDFAPVERYALMLLRQ
CCCCCCCEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLELTVFFSGALVMVLEMVGARVLAPYVGTSAIVWTSLIGVVLACLALGAWAGGRMADRH
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LSRRGLALALAGAGAGSALTALCHPLVGQWVTEGIGNLYVAAVAAAVGIFALPAFFFGMV
HHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPYAIRLRIGSLDTSGATVGRLYALSTAGSILGTFLGGFVLISFFGSSSILWGVAVCMLA
CCEEEEEEEECCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LSLCNAPGGAKGRAALLALCILGTAINGMYGNWREDRGSMHLVESPYNSIRVYEGTDWGE
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCC
GGRAVRLMATDPGYSQSGMYLDAPDELYFQYTRFYALGPYFVPHARSILMLGGGGYSVPK
CCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHEECCEECCCCCEEEEECCCCCCCCH
WILAGKSALAAPEDVRMTVVEIDPAMTDVARRWFALGDDVRLSVRHEDARAFLNRQDGRF
HHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCCCCCCE
DLVFVDVFNSHYAVPFQMGTVEAARALRRAVAPGGAVLMNVISAVEGEDGRLFQSIFKAL
EEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
STSFAEVQVYCVSRPDRPGEVQNLMVAAFPEKRDRAAPLAAGSTQVQLTEQKPVEMMLAT
CCCCEEEEEEEECCCCCCCHHHHEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
RYTGPLDFATLPLTDDFAPVERYALMLLRQ
CCCCCCCEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA