Click here to switch to the map view.

The map label for this gene is lutB [H]

Identifier: 220905253

GI number: 220905253

Start: 2396971

End: 2399121

Strand: Reverse

Name: lutB [H]

Synonym: Ddes_1991

Alternate gene names: 220905253

Gene position: 2399121-2396971 (Counterclockwise)

Preceding gene: 220905254

Following gene: 220905249

Centisome position: 83.49

GC content: 59.18

Gene sequence:

>2151_bases
ATGCATGACGCCCTTAAAAGCAGCTCCGGTTACCACAAGGAACTGGACGAAGCCCTGAACGACGAATTTTTGCGTCGCAC
CCTCGACACCTTTGCCGTGGCCTATCGCGCCAACCGCGAAGCCGTGTTCAAAGAAGTGGACGAACGCGCCCTCATTGCCC
AGGTGGCCGATGCCAAGGACTACGCCTGTCAGCATATGGAAGAACTGTACACCCAGTTCAAGGCCGAAGCTGAAAAGCGT
GGTGTGCATGTGCACCGCGCCGCTACGGCTGCCGAAGCCAACGAGATCATTTCGCGCATTGCCAGGGAAAACAACGTCAA
GCGCGTAGTGAAGTCCAAGTCGATGACGGCTGAAGAAATCGAGCTTACTCCTGCCCTTGAGGCCCAGGGCCTCATTGTGG
ATGAAACCGACCTTGGCGAATGGATCATCCAGTTGCGGCACGAAGGCCCTTCCCACATGGTCATGCCCGCCATCCATCTT
TCACGCTATCAGGTGGCCGATGACTTCACCAAGGCCACCGGCGTAAAGCAGGATTCGGACGTGCAGCACCTGGTCAAGGT
GGCCCGTGTGCAGCTGCGCCGCAAGTTCATTGCCGCGGATATGGGCATCAGCGGCTGTAACTTCGCCGTGGCCGAAAACG
GCTCGGTGTCCACCGTGACCAACGAGGGCAACGCCCGCATGGTCACCACACTGCCGCGCGTGCATGTGGCCATTGCCGGT
CTGGACAAGCTCGTTGCCAAGCTGGACGACGCCCTTACGGCCCTGCTGGTGCTGCCCCGCAACGCCACTGCCCAGCGCAT
CACCTCCTACGTCACCTGGATGTGCGGCGCGGGTCCCTGCGCGGCCAATGCGGACGATAAAAAGATCATGCATGTGGTCT
TTCTGGACAACGGGCGTACCGAGATTGCCAAGGATCCGCTGTTCAAGCAGATATTCCGCTGCGTGCGCTGCGGCGCCTGC
GCCAACGTCTGCCCCGTGTACCGCCTGGTGGGCGGCCACAAGATGGGCTACATCTACATTGGCGCCATTGGCCTTATTCT
TACCTACTTCTTCCACGGTAAAGACCGCGCGCGCATTCTGAGCCAGAACTGCATGGGATGCGAATCCTGCGCCAATGTGT
GCGCCGGCGGCATCGAGCTGCCGCGCCTCATCCGCGAAATCCGCGCGCGTCTCAATGAAGAGCAGGGCGCTCCCATTGAA
GCCAACCTGCTGTCGGCCGTCATGAAGAACCGCAAGCTCTTCCACCGGCTGCTCAAGTTCGCCAGCTTTGCCCAGAAGCC
CTTTACCCGCGGAACGCAGTTCCAGCGTCACCTGCCCTCAATATTTATGGGCAAGCACAACTTCAAGGCGCTGCCCGCCA
TCGCCAACAAGTCCTTCCGTGACCGCTGGCCCGAAATTGCGCCCAGGGTGCAGAATCCCACCATGCGTGTGGCCATCTTC
AGCGGCTGCGCCCAGGACTTCATCTACCCCGAGCAGCTGGAAGCCTGCGTGAAAATTCTTGCCGCCAAAAATGTGGCGGT
GGAATTCCCCATGGACCAGTCCTGCTGCGGCCTGCCCCTGGAAATGATGGGACAGCGCAAAACCTCCATTGATGTGGCCA
AGCAGAACATCGCGGCTTTCCGCGGCGGCAACTATGACTACATCATCACGCTCTGCGCAAGCTGCGCCGGGCACCTCAAA
CATCATTATCCGCAGATCCTGGACAAGGATTACGCAGTGGTGGAAGGTCAGGCCTTTGCGGCCAAGGTCATTGATTTCAG
CTCTTTTGTGCATGACGTGCTGGGCCTCAAGCCCGAAGACTTCCACAAGTCCGGGCAGAAGGTCACCTATCATGCTTCGT
GCCACCTCTGTCGTGGCCTGGGCGTGAAAAAGGCCCCCCGTGAGCTTATCGCTGACGCGGCGGAATACGTACCCTGCGAG
GAAGAAGAAGTCTGCTGCGGCTTTGGTGGCAGCTACTCCGTGAAGTTCCCCGAAATATCGGCGCAGCTTCTGGAAAAGAA
AATCAACAATATGAAGGCCACCGGAGCCGACCGCCTGGTGGTGGACTGCCCCGGCTGCGTCATGCAGCTGCGCGGCGGCG
CTGAAAAGCAGGGGCTGAAGATCAAGGTCGACCACATTTCGGAATTGCTGGCCGACAATCTGAAAAAATAA

Upstream 100 bases:

>100_bases
GGTGACGGGTCCCAGCCGCACGGCTGATATCGAACGTGTGGCTGCCGTGGGCGTACATGGCCCGCTGGAACTCCACATCA
TTCTTCTGGAGGACTAACCC

Downstream 100 bases:

>100_bases
GCCCTTCCGATAAACAGGTAAAAACAAAAACGCCGCTTGCTGATCCAAGCGGCGTTTTTGTTTTGGTGTGATGCCGGTCG
GCTGGCGGCTCAAAAAACTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MHDALKSSSGYHKELDEALNDEFLRRTLDTFAVAYRANREAVFKEVDERALIAQVADAKDYACQHMEELYTQFKAEAEKR
GVHVHRAATAAEANEIISRIARENNVKRVVKSKSMTAEEIELTPALEAQGLIVDETDLGEWIIQLRHEGPSHMVMPAIHL
SRYQVADDFTKATGVKQDSDVQHLVKVARVQLRRKFIAADMGISGCNFAVAENGSVSTVTNEGNARMVTTLPRVHVAIAG
LDKLVAKLDDALTALLVLPRNATAQRITSYVTWMCGAGPCAANADDKKIMHVVFLDNGRTEIAKDPLFKQIFRCVRCGAC
ANVCPVYRLVGGHKMGYIYIGAIGLILTYFFHGKDRARILSQNCMGCESCANVCAGGIELPRLIREIRARLNEEQGAPIE
ANLLSAVMKNRKLFHRLLKFASFAQKPFTRGTQFQRHLPSIFMGKHNFKALPAIANKSFRDRWPEIAPRVQNPTMRVAIF
SGCAQDFIYPEQLEACVKILAAKNVAVEFPMDQSCCGLPLEMMGQRKTSIDVAKQNIAAFRGGNYDYIITLCASCAGHLK
HHYPQILDKDYAVVEGQAFAAKVIDFSSFVHDVLGLKPEDFHKSGQKVTYHASCHLCRGLGVKKAPRELIADAAEYVPCE
EEEVCCGFGGSYSVKFPEISAQLLEKKINNMKATGADRLVVDCPGCVMQLRGGAEKQGLKIKVDHISELLADNLKK

Sequences:

>Translated_716_residues
MHDALKSSSGYHKELDEALNDEFLRRTLDTFAVAYRANREAVFKEVDERALIAQVADAKDYACQHMEELYTQFKAEAEKR
GVHVHRAATAAEANEIISRIARENNVKRVVKSKSMTAEEIELTPALEAQGLIVDETDLGEWIIQLRHEGPSHMVMPAIHL
SRYQVADDFTKATGVKQDSDVQHLVKVARVQLRRKFIAADMGISGCNFAVAENGSVSTVTNEGNARMVTTLPRVHVAIAG
LDKLVAKLDDALTALLVLPRNATAQRITSYVTWMCGAGPCAANADDKKIMHVVFLDNGRTEIAKDPLFKQIFRCVRCGAC
ANVCPVYRLVGGHKMGYIYIGAIGLILTYFFHGKDRARILSQNCMGCESCANVCAGGIELPRLIREIRARLNEEQGAPIE
ANLLSAVMKNRKLFHRLLKFASFAQKPFTRGTQFQRHLPSIFMGKHNFKALPAIANKSFRDRWPEIAPRVQNPTMRVAIF
SGCAQDFIYPEQLEACVKILAAKNVAVEFPMDQSCCGLPLEMMGQRKTSIDVAKQNIAAFRGGNYDYIITLCASCAGHLK
HHYPQILDKDYAVVEGQAFAAKVIDFSSFVHDVLGLKPEDFHKSGQKVTYHASCHLCRGLGVKKAPRELIADAAEYVPCE
EEEVCCGFGGSYSVKFPEISAQLLEKKINNMKATGADRLVVDCPGCVMQLRGGAEKQGLKIKVDHISELLADNLKK
>Mature_716_residues
MHDALKSSSGYHKELDEALNDEFLRRTLDTFAVAYRANREAVFKEVDERALIAQVADAKDYACQHMEELYTQFKAEAEKR
GVHVHRAATAAEANEIISRIARENNVKRVVKSKSMTAEEIELTPALEAQGLIVDETDLGEWIIQLRHEGPSHMVMPAIHL
SRYQVADDFTKATGVKQDSDVQHLVKVARVQLRRKFIAADMGISGCNFAVAENGSVSTVTNEGNARMVTTLPRVHVAIAG
LDKLVAKLDDALTALLVLPRNATAQRITSYVTWMCGAGPCAANADDKKIMHVVFLDNGRTEIAKDPLFKQIFRCVRCGAC
ANVCPVYRLVGGHKMGYIYIGAIGLILTYFFHGKDRARILSQNCMGCESCANVCAGGIELPRLIREIRARLNEEQGAPIE
ANLLSAVMKNRKLFHRLLKFASFAQKPFTRGTQFQRHLPSIFMGKHNFKALPAIANKSFRDRWPEIAPRVQNPTMRVAIF
SGCAQDFIYPEQLEACVKILAAKNVAVEFPMDQSCCGLPLEMMGQRKTSIDVAKQNIAAFRGGNYDYIITLCASCAGHLK
HHYPQILDKDYAVVEGQAFAAKVIDFSSFVHDVLGLKPEDFHKSGQKVTYHASCHLCRGLGVKKAPRELIADAAEYVPCE
EEEVCCGFGGSYSVKFPEISAQLLEKKINNMKATGADRLVVDCPGCVMQLRGGAEKQGLKIKVDHISELLADNLKK

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=399, Percent_Identity=36.0902255639098, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1786497, Length=238, Percent_Identity=32.3529411764706, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1788576, Length=417, Percent_Identity=23.9808153477218, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI48994913, Length=421, Percent_Identity=22.0902612826603, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 79289; Mature: 79289

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDALKSSSGYHKELDEALNDEFLRRTLDTFAVAYRANREAVFKEVDERALIAQVADAKD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YACQHMEELYTQFKAEAEKRGVHVHRAATAAEANEIISRIARENNVKRVVKSKSMTAEEI
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
ELTPALEAQGLIVDETDLGEWIIQLRHEGPSHMVMPAIHLSRYQVADDFTKATGVKQDSD
ECCCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCH
VQHLVKVARVQLRRKFIAADMGISGCNFAVAENGSVSTVTNEGNARMVTTLPRVHVAIAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCEEEEECCHHHHHHHH
LDKLVAKLDDALTALLVLPRNATAQRITSYVTWMCGAGPCAANADDKKIMHVVFLDNGRT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCC
EIAKDPLFKQIFRCVRCGACANVCPVYRLVGGHKMGYIYIGAIGLILTYFFHGKDRARIL
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
SQNCMGCESCANVCAGGIELPRLIREIRARLNEEQGAPIEANLLSAVMKNRKLFHRLLKF
HHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ASFAQKPFTRGTQFQRHLPSIFMGKHNFKALPAIANKSFRDRWPEIAPRVQNPTMRVAIF
HHHHHCCCCCCCHHHHHCCHHHCCCCCCCCCHHHHCCCHHHCCHHHCCCCCCCCEEEEEE
SGCAQDFIYPEQLEACVKILAAKNVAVEFPMDQSCCGLPLEMMGQRKTSIDVAKQNIAAF
HHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
RGGNYDYIITLCASCAGHLKHHYPQILDKDYAVVEGQAFAAKVIDFSSFVHDVLGLKPED
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHH
FHKSGQKVTYHASCHLCRGLGVKKAPRELIADAAEYVPCEEEEVCCGFGGSYSVKFPEIS
HHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCEEECCHHH
AQLLEKKINNMKATGADRLVVDCPGCVMQLRGGAEKQGLKIKVDHISELLADNLKK
HHHHHHHHHCCCCCCCCEEEEECCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MHDALKSSSGYHKELDEALNDEFLRRTLDTFAVAYRANREAVFKEVDERALIAQVADAKD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YACQHMEELYTQFKAEAEKRGVHVHRAATAAEANEIISRIARENNVKRVVKSKSMTAEEI
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
ELTPALEAQGLIVDETDLGEWIIQLRHEGPSHMVMPAIHLSRYQVADDFTKATGVKQDSD
ECCCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCH
VQHLVKVARVQLRRKFIAADMGISGCNFAVAENGSVSTVTNEGNARMVTTLPRVHVAIAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCEEEEECCHHHHHHHH
LDKLVAKLDDALTALLVLPRNATAQRITSYVTWMCGAGPCAANADDKKIMHVVFLDNGRT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCC
EIAKDPLFKQIFRCVRCGACANVCPVYRLVGGHKMGYIYIGAIGLILTYFFHGKDRARIL
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
SQNCMGCESCANVCAGGIELPRLIREIRARLNEEQGAPIEANLLSAVMKNRKLFHRLLKF
HHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ASFAQKPFTRGTQFQRHLPSIFMGKHNFKALPAIANKSFRDRWPEIAPRVQNPTMRVAIF
HHHHHCCCCCCCHHHHHCCHHHCCCCCCCCCHHHHCCCHHHCCHHHCCCCCCCCEEEEEE
SGCAQDFIYPEQLEACVKILAAKNVAVEFPMDQSCCGLPLEMMGQRKTSIDVAKQNIAAF
HHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
RGGNYDYIITLCASCAGHLKHHYPQILDKDYAVVEGQAFAAKVIDFSSFVHDVLGLKPED
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHH
FHKSGQKVTYHASCHLCRGLGVKKAPRELIADAAEYVPCEEEEVCCGFGGSYSVKFPEIS
HHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCEEECCHHH
AQLLEKKINNMKATGADRLVVDCPGCVMQLRGGAEKQGLKIKVDHISELLADNLKK
HHHHHHHHHCCCCCCCCEEEEECCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA