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The map label for this gene is zraR [H]

Identifier: 220904833

GI number: 220904833

Start: 1883306

End: 1883686

Strand: Reverse

Name: zraR [H]

Synonym: Ddes_1566

Alternate gene names: 220904833

Gene position: 1883686-1883306 (Counterclockwise)

Preceding gene: 220904834

Following gene: 220904832

Centisome position: 65.56

GC content: 57.74

Gene sequence:

>381_bases
ATGCGCGCACTGTTTGTGGACGACGAACTGGAATTTCTTGAACTTATGCAAAAACGCCTTGCCCGGCGCGGCATGGAAGT
GGTCACTGCCCCCGACGGGCAGACCGCGCTGAATATGGTGGAAGAAAACCTCGCTTCCGGCGGTGAACCTTTCAATATTG
TGGTGATGGACGTGCGCATGCCCGGCATGGACGGCCTTGAAACCCTGCGGCACATGAAGCAGAAATCTCCCGGTCTGCCC
GTCATACTGCTGACGGGCCATGCCTGCATGGGGGTGGCTGTGGAGGGGCTTGACCTTGGCGCGTATGACTACATGCTCAA
GCCCGTAGCCATCAGCGAGCTTATCATCAAGATGGAGGAAGCGGTTCGCTCCGCTGTGTAA

Upstream 100 bases:

>100_bases
CTAACTATACGCTCCGGCGTCACTTGCTGCACGAGACACGTCATCGGTATCGGCCCTGGCTTGGCCTGGCCGAGACATTG
CCTGAAACCGAGGAGGCCCC

Downstream 100 bases:

>100_bases
GATGGCGCTCCTCAAATATTTGCGGCACTGGATAGGGCGGGACCAGCCCGGGGAGCCAGACCCTGAGGAACTGGCCCGGG
AGGAAGAGCTGAAGATGCGC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MRALFVDDELEFLELMQKRLARRGMEVVTAPDGQTALNMVEENLASGGEPFNIVVMDVRMPGMDGLETLRHMKQKSPGLP
VILLTGHACMGVAVEGLDLGAYDYMLKPVAISELIIKMEEAVRSAV

Sequences:

>Translated_126_residues
MRALFVDDELEFLELMQKRLARRGMEVVTAPDGQTALNMVEENLASGGEPFNIVVMDVRMPGMDGLETLRHMKQKSPGLP
VILLTGHACMGVAVEGLDLGAYDYMLKPVAISELIIKMEEAVRSAV
>Mature_126_residues
MRALFVDDELEFLELMQKRLARRGMEVVTAPDGQTALNMVEENLASGGEPFNIVVMDVRMPGMDGLETLRHMKQKSPGLP
VILLTGHACMGVAVEGLDLGAYDYMLKPVAISELIIKMEEAVRSAV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=37.7049180327869, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=36.1344537815126, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790299, Length=117, Percent_Identity=37.6068376068376, Blast_Score=79, Evalue=7e-17,
Organism=Escherichia coli, GI1789402, Length=123, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1786784, Length=123, Percent_Identity=30.8943089430894, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=126, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1790552, Length=94, Percent_Identity=37.2340425531915, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=27.0491803278689, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=124, Percent_Identity=29.8387096774194, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=31.9672131147541, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 13833; Mature: 13833

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
8.7 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
8.7 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALFVDDELEFLELMQKRLARRGMEVVTAPDGQTALNMVEENLASGGEPFNIVVMDVRM
CCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEC
PGMDGLETLRHMKQKSPGLPVILLTGHACMGVAVEGLDLGAYDYMLKPVAISELIIKMEE
CCCCHHHHHHHHHHCCCCCCEEEEECCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AVRSAV
HHHHCC
>Mature Secondary Structure
MRALFVDDELEFLELMQKRLARRGMEVVTAPDGQTALNMVEENLASGGEPFNIVVMDVRM
CCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEC
PGMDGLETLRHMKQKSPGLPVILLTGHACMGVAVEGLDLGAYDYMLKPVAISELIIKMEE
CCCCHHHHHHHHHHCCCCCCEEEEECCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
AVRSAV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]