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The map label for this gene is radA [H]

Identifier: 220904700

GI number: 220904700

Start: 1713730

End: 1715106

Strand: Reverse

Name: radA [H]

Synonym: Ddes_1432

Alternate gene names: 220904700

Gene position: 1715106-1713730 (Counterclockwise)

Preceding gene: 220904701

Following gene: 220904699

Centisome position: 59.69

GC content: 61.29

Gene sequence:

>1377_bases
ATGGCGAAACTACGTGAAATATATATATGCTCTTCGTGTGGTGCGCAGACAATGCAATGGCGGGGGCAGTGTCCCGGCTG
CCATGAGTGGAACACGCTGGAAGCCTCGGTACAGGCCCGTTCTTCGGGCAAGACTCGCACATCTCTGGGCGACAGCAGCG
CGTCCGGACGCCCCGTTGCCCTGTGCCAGGTGGAGGACGCAGGTCACGAACCTTACGGTAGCGGTCTGCAAGCCCTGGAC
AGGGTGCTGGGCAAGGGGCTTGTACCCGGGGCGGCCATTCTTGTGGGCGGCGAGCCCGGCATAGGCAAATCCACGCTTCT
TTTGCAGGTGGCCGGGCTTGTGGCCGCTCAGATGGCTTCTGCCGGTCGTCCCGTGCTGTACGCCAGTGGTGAGGAATCGC
TGCCGCAGATCAAGGGCAGGGCCGAGCGTCTGGGCATGCTTGACCCCAATCTGCTGGCCCTTGCCACGTCCCGCGTGGAA
GACGTGGTAGAGGCCGCTAATGCGCAAAATCCGGCCCTGCTCGTAGTGGACTCGGTGCAGACCCTCACAAGTCTTGAGGC
CGAAGGCTTGCCCGGCAATGTCAGCCAGGTGCGGGCCGTTGCCACTTCTTTGCTTGAACTGTGCCGCCGACTGGGCTGCA
CTCTCATACTTGTGGGGCATGTGACCAAGGATGGGGTGCTGGCCGGGCCGAGGCTGCTGGAGCATATGGTGGACACGGTC
ATTTCTCTTGAAGGCGACCGGCGGCAGATGTTCCGCCTGTTGCGCGTGTTCAAGAACCGTTTTGGTCCCAATGAGGAACT
GCTGGTATTTCGCATGGGCCAGCGGGGCATGGAAGTGGTGGATGACCCTTCCACATTTTTTCTCGGCCAGCGCGACGCGT
CCTTGTCGGGTACGGCGGTGGTTATGGCTGTGGACGGCCAGCGGCCCCTTGCAGTAGAGGTGCAGGCTCTTGTGTCCCGC
ACTTTTCTGAGCATTCCGCGCCGCGCTGCTCTGGGTTTTGATGTGGGCCGCCTGCACCTGCTTTTGGCCGTGCTTGAAAA
AAGGCTCAAGCTCAACTTTGCCCAGGTGGATATTTACGCCAAGGTGGGCGGAGGCATGAAGCTCAACGAGCCGGGACTGG
ATCTCGCCCTGGTAGCTGCGGTGCTTTCATCCTATTATGACGTGCCATTGCCCGAAAAAAGCGTGCTGTGGGGTGAAGTG
GACCTTAACGGGCAGGTGCGTCCTGTGGCCGCGCAGGATCTGCGCCTTACTCAGGCCCGGCGTCTGGGCTTTGACCCCAT
TGTGCACCCCGGGGATGAAAAGGGCGGCATTGCGACCATCGCAGCCTTGCAGCAGCGGCTTTTTCACCGCCGTCACAAAG
CGGAGGATGGTGAGTGA

Upstream 100 bases:

>100_bases
AACTATATAAAGTTTCCTTTTTCGTCCCTCTGGCGTTTGCTTGCGCAGGCGTCGGGTAACCTGCCTTGCGCCCTCCGTGC
TTTTTCCGTAGGCTTGAAGC

Downstream 100 bases:

>100_bases
TGGCGCTGGAAGTGGAACGCAAATTTCCGGATGTAAAGCTGGACAGCCTGCGCCGCAAGCTTGCCGAGGCGGGTGCTTTT
TGTCTTGGCGCGCACTTTGA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MAKLREIYICSSCGAQTMQWRGQCPGCHEWNTLEASVQARSSGKTRTSLGDSSASGRPVALCQVEDAGHEPYGSGLQALD
RVLGKGLVPGAAILVGGEPGIGKSTLLLQVAGLVAAQMASAGRPVLYASGEESLPQIKGRAERLGMLDPNLLALATSRVE
DVVEAANAQNPALLVVDSVQTLTSLEAEGLPGNVSQVRAVATSLLELCRRLGCTLILVGHVTKDGVLAGPRLLEHMVDTV
ISLEGDRRQMFRLLRVFKNRFGPNEELLVFRMGQRGMEVVDDPSTFFLGQRDASLSGTAVVMAVDGQRPLAVEVQALVSR
TFLSIPRRAALGFDVGRLHLLLAVLEKRLKLNFAQVDIYAKVGGGMKLNEPGLDLALVAAVLSSYYDVPLPEKSVLWGEV
DLNGQVRPVAAQDLRLTQARRLGFDPIVHPGDEKGGIATIAALQQRLFHRRHKAEDGE

Sequences:

>Translated_458_residues
MAKLREIYICSSCGAQTMQWRGQCPGCHEWNTLEASVQARSSGKTRTSLGDSSASGRPVALCQVEDAGHEPYGSGLQALD
RVLGKGLVPGAAILVGGEPGIGKSTLLLQVAGLVAAQMASAGRPVLYASGEESLPQIKGRAERLGMLDPNLLALATSRVE
DVVEAANAQNPALLVVDSVQTLTSLEAEGLPGNVSQVRAVATSLLELCRRLGCTLILVGHVTKDGVLAGPRLLEHMVDTV
ISLEGDRRQMFRLLRVFKNRFGPNEELLVFRMGQRGMEVVDDPSTFFLGQRDASLSGTAVVMAVDGQRPLAVEVQALVSR
TFLSIPRRAALGFDVGRLHLLLAVLEKRLKLNFAQVDIYAKVGGGMKLNEPGLDLALVAAVLSSYYDVPLPEKSVLWGEV
DLNGQVRPVAAQDLRLTQARRLGFDPIVHPGDEKGGIATIAALQQRLFHRRHKAEDGE
>Mature_457_residues
AKLREIYICSSCGAQTMQWRGQCPGCHEWNTLEASVQARSSGKTRTSLGDSSASGRPVALCQVEDAGHEPYGSGLQALDR
VLGKGLVPGAAILVGGEPGIGKSTLLLQVAGLVAAQMASAGRPVLYASGEESLPQIKGRAERLGMLDPNLLALATSRVED
VVEAANAQNPALLVVDSVQTLTSLEAEGLPGNVSQVRAVATSLLELCRRLGCTLILVGHVTKDGVLAGPRLLEHMVDTVI
SLEGDRRQMFRLLRVFKNRFGPNEELLVFRMGQRGMEVVDDPSTFFLGQRDASLSGTAVVMAVDGQRPLAVEVQALVSRT
FLSIPRRAALGFDVGRLHLLLAVLEKRLKLNFAQVDIYAKVGGGMKLNEPGLDLALVAAVLSSYYDVPLPEKSVLWGEVD
LNGQVRPVAAQDLRLTQARRLGFDPIVHPGDEKGGIATIAALQQRLFHRRHKAEDGE

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=435, Percent_Identity=42.2988505747126, Blast_Score=335, Evalue=3e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49066; Mature: 48935

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLREIYICSSCGAQTMQWRGQCPGCHEWNTLEASVQARSSGKTRTSLGDSSASGRPVA
CCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEE
LCQVEDAGHEPYGSGLQALDRVLGKGLVPGAAILVGGEPGIGKSTLLLQVAGLVAAQMAS
EEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
AGRPVLYASGEESLPQIKGRAERLGMLDPNLLALATSRVEDVVEAANAQNPALLVVDSVQ
CCCCEEEECCCCCCHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHH
TLTSLEAEGLPGNVSQVRAVATSLLELCRRLGCTLILVGHVTKDGVLAGPRLLEHMVDTV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
ISLEGDRRQMFRLLRVFKNRFGPNEELLVFRMGQRGMEVVDDPSTFFLGQRDASLSGTAV
HHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCCEE
VMAVDGQRPLAVEVQALVSRTFLSIPRRAALGFDVGRLHLLLAVLEKRLKLNFAQVDIYA
EEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
KVGGGMKLNEPGLDLALVAAVLSSYYDVPLPEKSVLWGEVDLNGQVRPVAAQDLRLTQAR
EECCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
RLGFDPIVHPGDEKGGIATIAALQQRLFHRRHKAEDGE
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKLREIYICSSCGAQTMQWRGQCPGCHEWNTLEASVQARSSGKTRTSLGDSSASGRPVA
CCCEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEE
LCQVEDAGHEPYGSGLQALDRVLGKGLVPGAAILVGGEPGIGKSTLLLQVAGLVAAQMAS
EEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
AGRPVLYASGEESLPQIKGRAERLGMLDPNLLALATSRVEDVVEAANAQNPALLVVDSVQ
CCCCEEEECCCCCCHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHH
TLTSLEAEGLPGNVSQVRAVATSLLELCRRLGCTLILVGHVTKDGVLAGPRLLEHMVDTV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
ISLEGDRRQMFRLLRVFKNRFGPNEELLVFRMGQRGMEVVDDPSTFFLGQRDASLSGTAV
HHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCCEE
VMAVDGQRPLAVEVQALVSRTFLSIPRRAALGFDVGRLHLLLAVLEKRLKLNFAQVDIYA
EEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
KVGGGMKLNEPGLDLALVAAVLSSYYDVPLPEKSVLWGEVDLNGQVRPVAAQDLRLTQAR
EECCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
RLGFDPIVHPGDEKGGIATIAALQQRLFHRRHKAEDGE
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]