Click here to switch to the map view.

The map label for this gene is ruvA [H]

Identifier: 220904537

GI number: 220904537

Start: 1497101

End: 1497715

Strand: Reverse

Name: ruvA [H]

Synonym: Ddes_1268

Alternate gene names: 220904537

Gene position: 1497715-1497101 (Counterclockwise)

Preceding gene: 220904538

Following gene: 220904536

Centisome position: 52.12

GC content: 57.07

Gene sequence:

>615_bases
ATGATAGCCTATCTTGAGGGCCGCCTGGCCGAAACATGGGGCAACACCTGTCTGCTCATTACCGAAAACGGCGTGGGCTA
TGCAGTGGCCTTGCCTGCGCATACCCTGTCCGTCCTGCCAGGCCGGGGAGAGCACCTTGCCCTGTATACCAGTCTCGCCG
TGCGCGAAGACGCGCTTGAACTTTTCGGATTTGCCACTTTTGAAGAGCGGCAGACGTTTGAGGTACTCATATCCATATCC
AAGGTGGGAGCGCGTACCGCTTTGTCCATTCTTTCCATTTACAGGCCCGAAGATCTGCGACGCATCGTGTTTGAAGAAGA
CGTGATGGCCCTCACCCGTGTTTCGGGCATCGGCAAGAAAACCGCGCAGCATGTTTTTCTGGAACTTAAATACAAACTCA
AGGTGGATGATGTTCCGCAGGCTGCGGTGCTGGCTTCCACGGGGGAAAGGCCGGGATCCGTCTTCAGGGATGTGCTCGAT
GGCCTTGCCAACCTGGGCTACGCTGAAGATGAGTGTGCCCCGATGGTCAAAAAGCTGCTGCATGAAGAACCTGATCTGGA
TGTGACCGGCGCGCTCAGGGCTGCCTTGAAGGCCCTGGCCAGGGGGAGAGCCTGA

Upstream 100 bases:

>100_bases
GGCCTATTTGAAAAAACAGGGCATTCGGTTATGCTGGCTGCGGTATGCGCACCTGTGGGGCTGCGCTGCCGGTATTATCC
ATCTGACCCGCAAGGAATCC

Downstream 100 bases:

>100_bases
TGGCGGAAACTTGTCAGCCCCAGGGGGCCGTCAATATTGATGAAAGCGTACGGCCGCGCAGTCTGGAAGATTTTATCGGT
CAGGATGACCTGCGGGCCAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIAYLEGRLAETWGNTCLLITENGVGYAVALPAHTLSVLPGRGEHLALYTSLAVREDALELFGFATFEERQTFEVLISIS
KVGARTALSILSIYRPEDLRRIVFEEDVMALTRVSGIGKKTAQHVFLELKYKLKVDDVPQAAVLASTGERPGSVFRDVLD
GLANLGYAEDECAPMVKKLLHEEPDLDVTGALRAALKALARGRA

Sequences:

>Translated_204_residues
MIAYLEGRLAETWGNTCLLITENGVGYAVALPAHTLSVLPGRGEHLALYTSLAVREDALELFGFATFEERQTFEVLISIS
KVGARTALSILSIYRPEDLRRIVFEEDVMALTRVSGIGKKTAQHVFLELKYKLKVDDVPQAAVLASTGERPGSVFRDVLD
GLANLGYAEDECAPMVKKLLHEEPDLDVTGALRAALKALARGRA
>Mature_204_residues
MIAYLEGRLAETWGNTCLLITENGVGYAVALPAHTLSVLPGRGEHLALYTSLAVREDALELFGFATFEERQTFEVLISIS
KVGARTALSILSIYRPEDLRRIVFEEDVMALTRVSGIGKKTAQHVFLELKYKLKVDDVPQAAVLASTGERPGSVFRDVLD
GLANLGYAEDECAPMVKKLLHEEPDLDVTGALRAALKALARGRA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=34.3137254901961, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22256; Mature: 22256

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAYLEGRLAETWGNTCLLITENGVGYAVALPAHTLSVLPGRGEHLALYTSLAVREDALE
CEEEECCCHHHHCCCEEEEEEECCCCEEEEECCHHHHHCCCCCCEEEEEHHHHHHHHHHH
LFGFATFEERQTFEVLISISKVGARTALSILSIYRPEDLRRIVFEEDVMALTRVSGIGKK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
TAQHVFLELKYKLKVDDVPQAAVLASTGERPGSVFRDVLDGLANLGYAEDECAPMVKKLL
HHHHEEEEEEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HEEPDLDVTGALRAALKALARGRA
CCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIAYLEGRLAETWGNTCLLITENGVGYAVALPAHTLSVLPGRGEHLALYTSLAVREDALE
CEEEECCCHHHHCCCEEEEEEECCCCEEEEECCHHHHHCCCCCCEEEEEHHHHHHHHHHH
LFGFATFEERQTFEVLISISKVGARTALSILSIYRPEDLRRIVFEEDVMALTRVSGIGKK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
TAQHVFLELKYKLKVDDVPQAAVLASTGERPGSVFRDVLDGLANLGYAEDECAPMVKKLL
HHHHEEEEEEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HEEPDLDVTGALRAALKALARGRA
CCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA