Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 220904536

GI number: 220904536

Start: 1496118

End: 1497101

Strand: Reverse

Name: ruvB [H]

Synonym: Ddes_1267

Alternate gene names: 220904536

Gene position: 1497101-1496118 (Counterclockwise)

Preceding gene: 220904537

Following gene: 220904535

Centisome position: 52.1

GC content: 55.39

Gene sequence:

>984_bases
ATGGCGGAAACTTGTCAGCCCCAGGGGGCCGTCAATATTGATGAAAGCGTACGGCCGCGCAGTCTGGAAGATTTTATCGG
TCAGGATGACCTGCGGGCCAACCTGCGCGTCTACTTAGACGCTGCCCGTGAACGTGGCAAAGCGCTTGATCATACGCTTT
TTTACGGCAACCCCGGCTTGGGCAAGACTACGCTTGCCCAGATCATGGCCACGGAGCTTGGCGTCAACCTTGTGTGTACT
TCAGGGCCGGTGCTTGAACGCAGTGGCGATTTAGCCGCTATTCTCACAAATCTTGGCAGCCACGATATTCTTTTTGTTGA
TGAAATTCATCGCATGCCCATCGCGGTTGAAGAAGTGCTGTATCCGGCCATGGAGGACTTCAAGCTTGATCTGGTTATCG
GTCAGGGACCAGCGGCCCGCACCGTGAAGATTGACCTTGAACCCTTTACCCTGGTGGGAGCCACCACGCGCATGGGGCTT
ATTTCTTCCCCTTTGCGCGACCGTTTCGGTATTGTGGCACGGCTTGAGTATTACAGTTCGGCTGATCTGGCCCGGGTGGT
GCAGCGAACCGCCCGCATTCTCGGTGTGACCATCACGCCTGATGGTGCGGAGGAAATAGGGCGCCGTTCACGTGGTACGC
CGCGTATTGCCAACCGGCTGCTGCGTCGCGTACGAGATTTTGCTCTTGTGCACGGCAACGGGCAGGTGAACGGACATGAA
GCCTCCGTTGCGCTCAAGCGCATGGACGTGGATGAGCACGGTCTGGATCAGATGGACCGTAAACTCTTGGAAGTACTTAT
TAAACACTATGATGGCGGCCCGGTAGGCATAAAAACGCTGGCGGTCGCCTGTTCTGAAGAAGTGCGCACAATTGAAGATA
TTTATGAACCGTACCTTATCCAGTGCGGTTTTCTCAAACGTACTCCGCGTGGCCGTATGGCCACCGCACGGGCTTATACC
CACCTGAAATTGCTGCTTTCCTGA

Upstream 100 bases:

>100_bases
GTGCCCCGATGGTCAAAAAGCTGCTGCATGAAGAACCTGATCTGGATGTGACCGGCGCGCTCAGGGCTGCCTTGAAGGCC
CTGGCCAGGGGGAGAGCCTG

Downstream 100 bases:

>100_bases
TACGCAACCGGAAGTCTCTTGCAAGCAGGCGGAGTTTTACGGCTTGCCTCGCGGCTGTCAGACCGTTTCGTGTCCCCATT
TCTTTTTGGCATCGGCAAGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAETCQPQGAVNIDESVRPRSLEDFIGQDDLRANLRVYLDAARERGKALDHTLFYGNPGLGKTTLAQIMATELGVNLVCT
SGPVLERSGDLAAILTNLGSHDILFVDEIHRMPIAVEEVLYPAMEDFKLDLVIGQGPAARTVKIDLEPFTLVGATTRMGL
ISSPLRDRFGIVARLEYYSSADLARVVQRTARILGVTITPDGAEEIGRRSRGTPRIANRLLRRVRDFALVHGNGQVNGHE
ASVALKRMDVDEHGLDQMDRKLLEVLIKHYDGGPVGIKTLAVACSEEVRTIEDIYEPYLIQCGFLKRTPRGRMATARAYT
HLKLLLS

Sequences:

>Translated_327_residues
MAETCQPQGAVNIDESVRPRSLEDFIGQDDLRANLRVYLDAARERGKALDHTLFYGNPGLGKTTLAQIMATELGVNLVCT
SGPVLERSGDLAAILTNLGSHDILFVDEIHRMPIAVEEVLYPAMEDFKLDLVIGQGPAARTVKIDLEPFTLVGATTRMGL
ISSPLRDRFGIVARLEYYSSADLARVVQRTARILGVTITPDGAEEIGRRSRGTPRIANRLLRRVRDFALVHGNGQVNGHE
ASVALKRMDVDEHGLDQMDRKLLEVLIKHYDGGPVGIKTLAVACSEEVRTIEDIYEPYLIQCGFLKRTPRGRMATARAYT
HLKLLLS
>Mature_326_residues
AETCQPQGAVNIDESVRPRSLEDFIGQDDLRANLRVYLDAARERGKALDHTLFYGNPGLGKTTLAQIMATELGVNLVCTS
GPVLERSGDLAAILTNLGSHDILFVDEIHRMPIAVEEVLYPAMEDFKLDLVIGQGPAARTVKIDLEPFTLVGATTRMGLI
SSPLRDRFGIVARLEYYSSADLARVVQRTARILGVTITPDGAEEIGRRSRGTPRIANRLLRRVRDFALVHGNGQVNGHEA
SVALKRMDVDEHGLDQMDRKLLEVLIKHYDGGPVGIKTLAVACSEEVRTIEDIYEPYLIQCGFLKRTPRGRMATARAYTH
LKLLLS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=309, Percent_Identity=61.1650485436893, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 36097; Mature: 35966

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETCQPQGAVNIDESVRPRSLEDFIGQDDLRANLRVYLDAARERGKALDHTLFYGNPGL
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHCHHHHEEHHHHHCCCHHCCEEEECCCCC
GKTTLAQIMATELGVNLVCTSGPVLERSGDLAAILTNLGSHDILFVDEIHRMPIAVEEVL
CHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEEHHHCCCHHHHHHH
YPAMEDFKLDLVIGQGPAARTVKIDLEPFTLVGATTRMGLISSPLRDRFGIVARLEYYSS
HHHHHCCEEEEEEECCCCCEEEEEECCCEEEECCHHHHHHHHCCHHHHHCCEEEEHHHCC
ADLARVVQRTARILGVTITPDGAEEIGRRSRGTPRIANRLLRRVRDFALVHGNGQVNGHE
HHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHH
ASVALKRMDVDEHGLDQMDRKLLEVLIKHYDGGPVGIKTLAVACSEEVRTIEDIYEPYLI
HHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
QCGFLKRTPRGRMATARAYTHLKLLLS
ECCCCCCCCCCCHHHHHHHHHEEEEEC
>Mature Secondary Structure 
AETCQPQGAVNIDESVRPRSLEDFIGQDDLRANLRVYLDAARERGKALDHTLFYGNPGL
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHCHHHHEEHHHHHCCCHHCCEEEECCCCC
GKTTLAQIMATELGVNLVCTSGPVLERSGDLAAILTNLGSHDILFVDEIHRMPIAVEEVL
CHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEEHHHCCCHHHHHHH
YPAMEDFKLDLVIGQGPAARTVKIDLEPFTLVGATTRMGLISSPLRDRFGIVARLEYYSS
HHHHHCCEEEEEEECCCCCEEEEEECCCEEEECCHHHHHHHHCCHHHHHCCEEEEHHHCC
ADLARVVQRTARILGVTITPDGAEEIGRRSRGTPRIANRLLRRVRDFALVHGNGQVNGHE
HHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHH
ASVALKRMDVDEHGLDQMDRKLLEVLIKHYDGGPVGIKTLAVACSEEVRTIEDIYEPYLI
HHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
QCGFLKRTPRGRMATARAYTHLKLLLS
ECCCCCCCCCCCHHHHHHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA