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The map label for this gene is celB [H]

Identifier: 220904479

GI number: 220904479

Start: 1422650

End: 1424293

Strand: Direct

Name: celB [H]

Synonym: Ddes_1209

Alternate gene names: 220904479

Gene position: 1422650-1424293 (Clockwise)

Preceding gene: 220904478

Following gene: 220904482

Centisome position: 49.51

GC content: 53.89

Gene sequence:

>1644_bases
ATGCCTGTTGTTCATGCCCGGGCCGGACAATTGCCCCTGCCTGAAGATCTTGAAAATATCCCGGCGCTTGTCAGCGCCTA
TTTTACAGAATATCCCAATCCCGCAATTCCGGCCCAGCGTGTGAGTTTCGGAACTTCCGGGCATAGAGGTTCTTCGCAGC
TTCATACCTTTAATGAAGAGCATATATACGCCATTACACAGGCAGTATGCGACTATAGAAAGGTCAAAGGCATTGACGGT
CCTCTTTTTCTCGGCGGTGATACTCACGCTCTGTCTGAAGCGGCTTTTCGTTCTGCCCTTGAAGTTCTGGTAGCCAACGA
TGTGCATGTGCGCATTGCACCACGTGGCATCTACACTGCCACCCCCGCCATATCACATGCCATATTGCGTTGGAATGCAG
GGCGCTCCAAGGGGTTGGCCGATGGTATCGTTATTACCCCCTCGCATAACCCCCCTCGCGATGGCGGATTCAAGTACAAC
CCCCCACACGGGGGGCCGGCAGAGACCGACGTTACCGACAGGATAGAAAAAGGAGCCAATGCCTATCTTGAAAACGGCAA
TCGCGGAGTTCATCTCACACACCTGCGGGCGGCGCAGTCCTCTTCGCTGGTGGAAGAATACAACTTTATCCGCACCTATG
TGGATGACTTGCCTAATGTCCTGGATGTAAAGGCCATCGCAGCCTCGGGCCTGCGACTTGGCGTTGATCCGCTTGGCGGA
GCGAGCCTGCAAATGTGGGAACCCATAGCTGACGCCTATGGGATTGAAATTACTGTGGTGAATAAAGCCGTGGACCCCAC
ATTCCGTTTTGTGCCTTTTGATAAGGACGGGAAAATCCGTATGGACTGCTCCTCGCCTTATGCCATGAATGGCCTTCTTG
AGATGCGTGACCGTTTTGATCTGGCCGTTGCCTGCGACCCCGATTCAGACCGCCACGGCATTGTCACGGGGCAGGGGTTG
ATGAACCCCAATCACTTCCTGTCTGTAGCCGCATGGTATTTGTTCCGTACGCGCCGCTCATGGTCATCTGCCAGTGGCAT
TGGCAAGACATTGGTAACCAGTGCTCTGCTGGACAGAGTGGGGCAGGAAGCAAACCGCCCGGTGGTAGAAGTGCCTGTGG
GGTTCAAGTGGTTCGTACCCTATCTTTTGAACGGACATTGTGGAATGGGGTGTGAAGAAAGCGCCGGGGCTTCGTTTCTG
CGCTTTGATGGCAGTCCATGGAGCACCGATAAGGATGGTCCTCTCATGTGCCTGCTGGCAGCGGAAATGTTGGCTGTGGA
GCAATCCTCCCCCGCTGAACTGTATGAAAAACTTACAGAACGCTTGGGCTGCCCAGTATATCAGCGGCTGGATGCCCCTG
CCGATGATCAGGTGCGCGCGAAGCTCAAGGCTTTAACGCCGGAAAGCGCTGATATTGCCAGCCTTGGCGGTTCGCCAGTT
ACAGAAATTATTACCAGAGCGCCTGGTAATGATGCTCCCATTGGGGGTATTAAAATTTCCAGCGCAGATGGCTGGTTTGC
TGTCCGCCCCTCGGGAACAGAACCCATATGCAAGGTGTATACAGAAAGTTTCAAGGGAGAAGAGCATCTTTGCGGCATAC
AAAAGGACGCCATGAACTTCCTGGAGCGACTGCTGAAAGACTGA

Upstream 100 bases:

>100_bases
TTCTGTGCGGAGGTAAAAGATAATCTGGTCTGAATGTCATGTCGCAGGCGTGACAATCCATAATATCTTATGGTAATTAA
CAAGACAGTGGAGGTACATC

Downstream 100 bases:

>100_bases
GCCTGAAAAACATAGCCTTCATGGCGCATATGTAATATAAAAAGCTCTCTTTCTACATTAGGAGAGCTTTTTATATAAAT
GGTATTTCCGGTTGGAATAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MPVVHARAGQLPLPEDLENIPALVSAYFTEYPNPAIPAQRVSFGTSGHRGSSQLHTFNEEHIYAITQAVCDYRKVKGIDG
PLFLGGDTHALSEAAFRSALEVLVANDVHVRIAPRGIYTATPAISHAILRWNAGRSKGLADGIVITPSHNPPRDGGFKYN
PPHGGPAETDVTDRIEKGANAYLENGNRGVHLTHLRAAQSSSLVEEYNFIRTYVDDLPNVLDVKAIAASGLRLGVDPLGG
ASLQMWEPIADAYGIEITVVNKAVDPTFRFVPFDKDGKIRMDCSSPYAMNGLLEMRDRFDLAVACDPDSDRHGIVTGQGL
MNPNHFLSVAAWYLFRTRRSWSSASGIGKTLVTSALLDRVGQEANRPVVEVPVGFKWFVPYLLNGHCGMGCEESAGASFL
RFDGSPWSTDKDGPLMCLLAAEMLAVEQSSPAELYEKLTERLGCPVYQRLDAPADDQVRAKLKALTPESADIASLGGSPV
TEIITRAPGNDAPIGGIKISSADGWFAVRPSGTEPICKVYTESFKGEEHLCGIQKDAMNFLERLLKD

Sequences:

>Translated_547_residues
MPVVHARAGQLPLPEDLENIPALVSAYFTEYPNPAIPAQRVSFGTSGHRGSSQLHTFNEEHIYAITQAVCDYRKVKGIDG
PLFLGGDTHALSEAAFRSALEVLVANDVHVRIAPRGIYTATPAISHAILRWNAGRSKGLADGIVITPSHNPPRDGGFKYN
PPHGGPAETDVTDRIEKGANAYLENGNRGVHLTHLRAAQSSSLVEEYNFIRTYVDDLPNVLDVKAIAASGLRLGVDPLGG
ASLQMWEPIADAYGIEITVVNKAVDPTFRFVPFDKDGKIRMDCSSPYAMNGLLEMRDRFDLAVACDPDSDRHGIVTGQGL
MNPNHFLSVAAWYLFRTRRSWSSASGIGKTLVTSALLDRVGQEANRPVVEVPVGFKWFVPYLLNGHCGMGCEESAGASFL
RFDGSPWSTDKDGPLMCLLAAEMLAVEQSSPAELYEKLTERLGCPVYQRLDAPADDQVRAKLKALTPESADIASLGGSPV
TEIITRAPGNDAPIGGIKISSADGWFAVRPSGTEPICKVYTESFKGEEHLCGIQKDAMNFLERLLKD
>Mature_546_residues
PVVHARAGQLPLPEDLENIPALVSAYFTEYPNPAIPAQRVSFGTSGHRGSSQLHTFNEEHIYAITQAVCDYRKVKGIDGP
LFLGGDTHALSEAAFRSALEVLVANDVHVRIAPRGIYTATPAISHAILRWNAGRSKGLADGIVITPSHNPPRDGGFKYNP
PHGGPAETDVTDRIEKGANAYLENGNRGVHLTHLRAAQSSSLVEEYNFIRTYVDDLPNVLDVKAIAASGLRLGVDPLGGA
SLQMWEPIADAYGIEITVVNKAVDPTFRFVPFDKDGKIRMDCSSPYAMNGLLEMRDRFDLAVACDPDSDRHGIVTGQGLM
NPNHFLSVAAWYLFRTRRSWSSASGIGKTLVTSALLDRVGQEANRPVVEVPVGFKWFVPYLLNGHCGMGCEESAGASFLR
FDGSPWSTDKDGPLMCLLAAEMLAVEQSSPAELYEKLTERLGCPVYQRLDAPADDQVRAKLKALTPESADIASLGGSPVT
EIITRAPGNDAPIGGIKISSADGWFAVRPSGTEPICKVYTESFKGEEHLCGIQKDAMNFLERLLKD

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=531, Percent_Identity=24.4821092278719, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI290463102, Length=434, Percent_Identity=26.2672811059908, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI21361621, Length=434, Percent_Identity=26.036866359447, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786904, Length=544, Percent_Identity=53.6764705882353, Blast_Score=576, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17535441, Length=452, Percent_Identity=28.0973451327434, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322722, Length=525, Percent_Identity=25.1428571428571, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323752, Length=455, Percent_Identity=23.7362637362637, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864244, Length=395, Percent_Identity=26.3291139240506, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59282; Mature: 59150

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVHARAGQLPLPEDLENIPALVSAYFTEYPNPAIPAQRVSFGTSGHRGSSQLHTFNEE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCCCC
HIYAITQAVCDYRKVKGIDGPLFLGGDTHALSEAAFRSALEVLVANDVHVRIAPRGIYTA
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEC
TPAISHAILRWNAGRSKGLADGIVITPSHNPPRDGGFKYNPPHGGPAETDVTDRIEKGAN
CHHHHHHHEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCH
AYLENGNRGVHLTHLRAAQSSSLVEEYNFIRTYVDDLPNVLDVKAIAASGLRLGVDPLGG
HHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCCC
ASLQMWEPIADAYGIEITVVNKAVDPTFRFVPFDKDGKIRMDCSSPYAMNGLLEMRDRFD
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCC
LAVACDPDSDRHGIVTGQGLMNPNHFLSVAAWYLFRTRRSWSSASGIGKTLVTSALLDRV
EEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GQEANRPVVEVPVGFKWFVPYLLNGHCGMGCEESAGASFLRFDGSPWSTDKDGPLMCLLA
HHHHCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHHHH
AEMLAVEQSSPAELYEKLTERLGCPVYQRLDAPADDQVRAKLKALTPESADIASLGGSPV
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCCHH
TEIITRAPGNDAPIGGIKISSADGWFAVRPSGTEPICKVYTESFKGEEHLCGIQKDAMNF
HHHHHCCCCCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHCCCCHHHCCCHHHHHHH
LERLLKD
HHHHHCC
>Mature Secondary Structure 
PVVHARAGQLPLPEDLENIPALVSAYFTEYPNPAIPAQRVSFGTSGHRGSSQLHTFNEE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCCCC
HIYAITQAVCDYRKVKGIDGPLFLGGDTHALSEAAFRSALEVLVANDVHVRIAPRGIYTA
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEC
TPAISHAILRWNAGRSKGLADGIVITPSHNPPRDGGFKYNPPHGGPAETDVTDRIEKGAN
CHHHHHHHEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCH
AYLENGNRGVHLTHLRAAQSSSLVEEYNFIRTYVDDLPNVLDVKAIAASGLRLGVDPLGG
HHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCCC
ASLQMWEPIADAYGIEITVVNKAVDPTFRFVPFDKDGKIRMDCSSPYAMNGLLEMRDRFD
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCC
LAVACDPDSDRHGIVTGQGLMNPNHFLSVAAWYLFRTRRSWSSASGIGKTLVTSALLDRV
EEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GQEANRPVVEVPVGFKWFVPYLLNGHCGMGCEESAGASFLRFDGSPWSTDKDGPLMCLLA
HHHHCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHHHH
AEMLAVEQSSPAELYEKLTERLGCPVYQRLDAPADDQVRAKLKALTPESADIASLGGSPV
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCCHH
TEIITRAPGNDAPIGGIKISSADGWFAVRPSGTEPICKVYTESFKGEEHLCGIQKDAMNF
HHHHHCCCCCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHCCCCHHHCCCHHHHHHH
LERLLKD
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]