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The map label for this gene is ftsK [H]

Identifier: 220904475

GI number: 220904475

Start: 1416111

End: 1418558

Strand: Direct

Name: ftsK [H]

Synonym: Ddes_1205

Alternate gene names: 220904475

Gene position: 1416111-1418558 (Clockwise)

Preceding gene: 220904474

Following gene: 220904476

Centisome position: 49.28

GC content: 57.68

Gene sequence:

>2448_bases
TTGAGTCTGCTCAGTTTTGACGCCAATGACCCCAGCCTCAACCATGTGGTCAGTGGCACTGTCGAAGTGCATAACAAGGC
TGGCCTTTTTGGCGCGTATACCGCGGGATTCCTCAACGACGTGTTTGGCGTGGCCGCCTTCCTCTGTCCGCTGGTTTTCG
GCGCATTGGGGGCGGCCTACGTCTCTCCTGCCTATGGCATGCACTGGTGGCGCTGGTGCGGCTTTTTTCTGCTTACCATC
TGTTTGCTTGTTGCTGGGGCGGCCTGGGATTTTTCCATCGGCGACATCTGGGGCGGCGGCATGGTCGGCAATGCTTTGCA
CAGCAATGCCAGCCGCTATCTCAGTCCGGGCGGTTCTGCCCTTGTGTGGTTTTTTGTCTTCCTGGCCGGGCTTCAGCTTG
CCTGGAATATCTCATGGTTTACCCTGGCCGGTCGGTTTGCCCACTGGTTGCGTGGCAAGCTTGAGGCAAGGTTTGCGTCC
ACAGAAGCCGGACAAGACGAAAAAACAAAAAAATCTGGCAAAAATGCTTCATCGTCAGGCAAGTCTGCCGCTCGTGAGCA
AGTCTTGCCTGAAATAGTGCGGCATACGTCGGAAGCCGTCACTGCGGAAAGCGAAGAAAAGCAACCTGCCCGTTTCCGGC
TGTCCTGGCCCATTTGGGGTTTTTTATCCCGCTGGCGCGATCGCCTGGGGGACATTCATCCCACAGCGGACTCCCTGCCT
GAAGTTTATGAAGAAAAAACTGTGGATCCAGGGGGCGCAGAATCTACGGCTCCTCTTGTTCCGGCTGATGCGGGGGACGA
TCCCTTCGCCGTGGCCCAGGACCTGAGCGGCCAGCCGTTGGTGGAGCAGGAGGGGGCAGTGTCGGATGAATCCATGCCGC
CCGTGCGGAAAAGTTCCGCCGTAGCAACTGCCGATGCAGCACCAGGAACGATTACTCCTGCCACTTCTCCTGGCGAGGCC
GGGCCTGCTAAAAAAAGCGGCCTGGGCGGTATGGTTGCTTCGGCATTTCGTAAAAAAGCGGCCCCCCCATTGCCGGGACT
TGACCTGCTGGCCCCTCCTTCTGCCAAAAGTGGTGGACTCAGCCGTGAAGATATTCAGGCCAGAGGCCAGGCGCTCATGG
CTTGTCTTAATGATTTTGATATCCAGAGTGAGCTTGTGCGCATCACTCCCGGCCCCGTGGTCACTATGTATGCGGTGCGT
CCGGCTCCCGGCATTCGCGTAAGCCGTATCGCCAACCTGAGCGATGACCTCGCCCTTGCTCTCAAGGCCGTGGCCATCCG
TATTCAAGCACCCATTCCCGGCTCTGACACCGTGGGGATAGAAATTCCCAACGAGCAACGCGAAACTGTCAATTTTCGTG
AACTGGCCGCTTCCGAAGCGTTTCGTAACGGCTGCGGTCCGCTGACAATGATTCTTGGCAAGGATATCGCGGGCAAGCCG
TTTATGGCAGATCTGGCACGCATGCCGCACCTTCTTGTGGCCGGAGCCACGGGAGCGGGCAAGAGTGTTTGCCTGAACGG
CATTCTCGTCAGCCTGCTGTACCGCACCCAGCCGCAGGATATGCAGCTGCTGCTTATAGACCCCAAGCGCATTGAAATGG
CTGTGTATGCCGACGCTCCGCACCTGGTGCACCCGGTGGTCACGGAGATGAATGAAGCCAAAAATGCTCTGGACTGGGCC
GTGCATGAAATGGATCGGCGTTATGCCGCCATGGCTCGTCTGGGGGTGCGCAATGTTGCAGGATTTAATCAAAAACTGGC
TGCGTACAAGGATGGCCTGCCGCCGGATTTCTCCGATCTGGAACCATTGCCCTATCTTGTTATTGTGATTGACGAACTGG
CCGACCTCATGATGACTGCGGCCCGCGAGGTCGAAACAAGTATTGTGCGCTTGGCACAGCTGGCGCGCGCGGCCGGAATT
CATATGATTCTGGCCACACAGAGGCCCAGCGTGGACGTGGTCACCGGCCTCATCAAAGCCAACTTTCCTTGCCGTATTTC
ATTCCAGGTCACTTCCAAGCATGACTCGCGCACCATTCTTGACCAGGTAGGGGCCGAACATCTGCTTGGCCGGGGCGATA
TGCTGTTCAAGCCCAGCGGGGGAAGACTGCAGCGCCTGCACGGTCCGTTCCTTAGTGATGAAGAAGTGCAGAGCGTGGTA
AATCACTGGAAGCGCCAGTTAAGCCCATCCTACAAGATCGACTTTGCCCAGTGGGGAATTGATGCTGCCGTTGCCGGCAA
CGGCAGCGGGGGGGGGGATGCGGCTCAGGACCCCCTGTATGGCGAGGTTCAGGCTTTCGTAAGCGAACAGGGCAGGGCAT
CAATTTCTCTTGTGCAGCGCCGCTTTAAAATTGGCTTTAACCGTGCGGCACGCCTGATTGAACAATTGGAACATGACGGT
ATCATTGGCCCGGCAGACGGCAGCAAGCCCCGCGCGGTGGTCAAATAA

Upstream 100 bases:

>100_bases
GGAATAATGCCCGGTTCGGGAGGGTAGCCCTACGGACGCCCATAAATTCAGCCGCGAACTTCTTGGCCTTTTTCTGCTCT
TCTGGGCACTGCTGCTTTTA

Downstream 100 bases:

>100_bases
CCTGAGCAGATTTTTTTTGAGATTGATTTTTCTGTCAGAGGCCCCACCGGGCCGTGGAGGTTGTATGCGTATGTTGCGCG
CGGCTATCGCCGCAATGGCC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MSLLSFDANDPSLNHVVSGTVEVHNKAGLFGAYTAGFLNDVFGVAAFLCPLVFGALGAAYVSPAYGMHWWRWCGFFLLTI
CLLVAGAAWDFSIGDIWGGGMVGNALHSNASRYLSPGGSALVWFFVFLAGLQLAWNISWFTLAGRFAHWLRGKLEARFAS
TEAGQDEKTKKSGKNASSSGKSAAREQVLPEIVRHTSEAVTAESEEKQPARFRLSWPIWGFLSRWRDRLGDIHPTADSLP
EVYEEKTVDPGGAESTAPLVPADAGDDPFAVAQDLSGQPLVEQEGAVSDESMPPVRKSSAVATADAAPGTITPATSPGEA
GPAKKSGLGGMVASAFRKKAAPPLPGLDLLAPPSAKSGGLSREDIQARGQALMACLNDFDIQSELVRITPGPVVTMYAVR
PAPGIRVSRIANLSDDLALALKAVAIRIQAPIPGSDTVGIEIPNEQRETVNFRELAASEAFRNGCGPLTMILGKDIAGKP
FMADLARMPHLLVAGATGAGKSVCLNGILVSLLYRTQPQDMQLLLIDPKRIEMAVYADAPHLVHPVVTEMNEAKNALDWA
VHEMDRRYAAMARLGVRNVAGFNQKLAAYKDGLPPDFSDLEPLPYLVIVIDELADLMMTAAREVETSIVRLAQLARAAGI
HMILATQRPSVDVVTGLIKANFPCRISFQVTSKHDSRTILDQVGAEHLLGRGDMLFKPSGGRLQRLHGPFLSDEEVQSVV
NHWKRQLSPSYKIDFAQWGIDAAVAGNGSGGGDAAQDPLYGEVQAFVSEQGRASISLVQRRFKIGFNRAARLIEQLEHDG
IIGPADGSKPRAVVK

Sequences:

>Translated_815_residues
MSLLSFDANDPSLNHVVSGTVEVHNKAGLFGAYTAGFLNDVFGVAAFLCPLVFGALGAAYVSPAYGMHWWRWCGFFLLTI
CLLVAGAAWDFSIGDIWGGGMVGNALHSNASRYLSPGGSALVWFFVFLAGLQLAWNISWFTLAGRFAHWLRGKLEARFAS
TEAGQDEKTKKSGKNASSSGKSAAREQVLPEIVRHTSEAVTAESEEKQPARFRLSWPIWGFLSRWRDRLGDIHPTADSLP
EVYEEKTVDPGGAESTAPLVPADAGDDPFAVAQDLSGQPLVEQEGAVSDESMPPVRKSSAVATADAAPGTITPATSPGEA
GPAKKSGLGGMVASAFRKKAAPPLPGLDLLAPPSAKSGGLSREDIQARGQALMACLNDFDIQSELVRITPGPVVTMYAVR
PAPGIRVSRIANLSDDLALALKAVAIRIQAPIPGSDTVGIEIPNEQRETVNFRELAASEAFRNGCGPLTMILGKDIAGKP
FMADLARMPHLLVAGATGAGKSVCLNGILVSLLYRTQPQDMQLLLIDPKRIEMAVYADAPHLVHPVVTEMNEAKNALDWA
VHEMDRRYAAMARLGVRNVAGFNQKLAAYKDGLPPDFSDLEPLPYLVIVIDELADLMMTAAREVETSIVRLAQLARAAGI
HMILATQRPSVDVVTGLIKANFPCRISFQVTSKHDSRTILDQVGAEHLLGRGDMLFKPSGGRLQRLHGPFLSDEEVQSVV
NHWKRQLSPSYKIDFAQWGIDAAVAGNGSGGGDAAQDPLYGEVQAFVSEQGRASISLVQRRFKIGFNRAARLIEQLEHDG
IIGPADGSKPRAVVK
>Mature_814_residues
SLLSFDANDPSLNHVVSGTVEVHNKAGLFGAYTAGFLNDVFGVAAFLCPLVFGALGAAYVSPAYGMHWWRWCGFFLLTIC
LLVAGAAWDFSIGDIWGGGMVGNALHSNASRYLSPGGSALVWFFVFLAGLQLAWNISWFTLAGRFAHWLRGKLEARFAST
EAGQDEKTKKSGKNASSSGKSAAREQVLPEIVRHTSEAVTAESEEKQPARFRLSWPIWGFLSRWRDRLGDIHPTADSLPE
VYEEKTVDPGGAESTAPLVPADAGDDPFAVAQDLSGQPLVEQEGAVSDESMPPVRKSSAVATADAAPGTITPATSPGEAG
PAKKSGLGGMVASAFRKKAAPPLPGLDLLAPPSAKSGGLSREDIQARGQALMACLNDFDIQSELVRITPGPVVTMYAVRP
APGIRVSRIANLSDDLALALKAVAIRIQAPIPGSDTVGIEIPNEQRETVNFRELAASEAFRNGCGPLTMILGKDIAGKPF
MADLARMPHLLVAGATGAGKSVCLNGILVSLLYRTQPQDMQLLLIDPKRIEMAVYADAPHLVHPVVTEMNEAKNALDWAV
HEMDRRYAAMARLGVRNVAGFNQKLAAYKDGLPPDFSDLEPLPYLVIVIDELADLMMTAAREVETSIVRLAQLARAAGIH
MILATQRPSVDVVTGLIKANFPCRISFQVTSKHDSRTILDQVGAEHLLGRGDMLFKPSGGRLQRLHGPFLSDEEVQSVVN
HWKRQLSPSYKIDFAQWGIDAAVAGNGSGGGDAAQDPLYGEVQAFVSEQGRASISLVQRRFKIGFNRAARLIEQLEHDGI
IGPADGSKPRAVVK

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=482, Percent_Identity=50.4149377593361, Blast_Score=467, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 87340; Mature: 87208

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLSFDANDPSLNHVVSGTVEVHNKAGLFGAYTAGFLNDVFGVAAFLCPLVFGALGAAY
CCEEECCCCCCCCHHEEECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSPAYGMHWWRWCGFFLLTICLLVAGAAWDFSIGDIWGGGMVGNALHSNASRYLSPGGSA
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCHH
LVWFFVFLAGLQLAWNISWFTLAGRFAHWLRGKLEARFASTEAGQDEKTKKSGKNASSSG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
KSAAREQVLPEIVRHTSEAVTAESEEKQPARFRLSWPIWGFLSRWRDRLGDIHPTADSLP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHH
EVYEEKTVDPGGAESTAPLVPADAGDDPFAVAQDLSGQPLVEQEGAVSDESMPPVRKSSA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
VATADAAPGTITPATSPGEAGPAKKSGLGGMVASAFRKKAAPPLPGLDLLAPPSAKSGGL
EEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SREDIQARGQALMACLNDFDIQSELVRITPGPVVTMYAVRPAPGIRVSRIANLSDDLALA
CHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHCCCHHHHHH
LKAVAIRIQAPIPGSDTVGIEIPNEQRETVNFRELAASEAFRNGCGPLTMILGKDIAGKP
HHHHHEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCC
FMADLARMPHLLVAGATGAGKSVCLNGILVSLLYRTQPQDMQLLLIDPKRIEMAVYADAP
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCC
HLVHPVVTEMNEAKNALDWAVHEMDRRYAAMARLGVRNVAGFNQKLAAYKDGLPPDFSDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC
EPLPYLVIVIDELADLMMTAAREVETSIVRLAQLARAAGIHMILATQRPSVDVVTGLIKA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHC
NFPCRISFQVTSKHDSRTILDQVGAEHLLGRGDMLFKPSGGRLQRLHGPFLSDEEVQSVV
CCCEEEEEEEECCCCHHHHHHHHCHHHHCCCCCEEECCCCCCHHHHCCCCCCHHHHHHHH
NHWKRQLSPSYKIDFAQWGIDAAVAGNGSGGGDAAQDPLYGEVQAFVSEQGRASISLVQR
HHHHHHCCCCCEEEHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
RFKIGFNRAARLIEQLEHDGIIGPADGSKPRAVVK
HHHHCHHHHHHHHHHHHHCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
SLLSFDANDPSLNHVVSGTVEVHNKAGLFGAYTAGFLNDVFGVAAFLCPLVFGALGAAY
CEEECCCCCCCCHHEEECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSPAYGMHWWRWCGFFLLTICLLVAGAAWDFSIGDIWGGGMVGNALHSNASRYLSPGGSA
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCHH
LVWFFVFLAGLQLAWNISWFTLAGRFAHWLRGKLEARFASTEAGQDEKTKKSGKNASSSG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCC
KSAAREQVLPEIVRHTSEAVTAESEEKQPARFRLSWPIWGFLSRWRDRLGDIHPTADSLP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHH
EVYEEKTVDPGGAESTAPLVPADAGDDPFAVAQDLSGQPLVEQEGAVSDESMPPVRKSSA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
VATADAAPGTITPATSPGEAGPAKKSGLGGMVASAFRKKAAPPLPGLDLLAPPSAKSGGL
EEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
SREDIQARGQALMACLNDFDIQSELVRITPGPVVTMYAVRPAPGIRVSRIANLSDDLALA
CHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHCCCHHHHHH
LKAVAIRIQAPIPGSDTVGIEIPNEQRETVNFRELAASEAFRNGCGPLTMILGKDIAGKP
HHHHHEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCCCC
FMADLARMPHLLVAGATGAGKSVCLNGILVSLLYRTQPQDMQLLLIDPKRIEMAVYADAP
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCC
HLVHPVVTEMNEAKNALDWAVHEMDRRYAAMARLGVRNVAGFNQKLAAYKDGLPPDFSDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC
EPLPYLVIVIDELADLMMTAAREVETSIVRLAQLARAAGIHMILATQRPSVDVVTGLIKA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHC
NFPCRISFQVTSKHDSRTILDQVGAEHLLGRGDMLFKPSGGRLQRLHGPFLSDEEVQSVV
CCCEEEEEEEECCCCHHHHHHHHCHHHHCCCCCEEECCCCCCHHHHCCCCCCHHHHHHHH
NHWKRQLSPSYKIDFAQWGIDAAVAGNGSGGGDAAQDPLYGEVQAFVSEQGRASISLVQR
HHHHHHCCCCCEEEHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
RFKIGFNRAARLIEQLEHDGIIGPADGSKPRAVVK
HHHHCHHHHHHHHHHHHHCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]