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The map label for this gene is lolA [H]

Identifier: 220904476

GI number: 220904476

Start: 1418623

End: 1419300

Strand: Direct

Name: lolA [H]

Synonym: Ddes_1206

Alternate gene names: 220904476

Gene position: 1418623-1419300 (Clockwise)

Preceding gene: 220904475

Following gene: 220904477

Centisome position: 49.37

GC content: 50.15

Gene sequence:

>678_bases
ATGCGTATGTTGCGCGCGGCTATCGCCGCAATGGCCCTGTGTCTCATTATGACTTCATTTGCAACGGCACAGAATACTGA
TATGGCTGCGGCCATCCAGGCGCGTTATGAAAAGCTTGGTTCCTTTGCTGCTGACTTCGACCAGACCCTTACACATAAAG
AAAGCGGCGCTGTAGAAAAAAGGCAAGGCAAGCTGCTTTTTAAAAAACCTCTGCTCATCCGCTGGCAAACGGTAACCCCA
CATGAAGAAACGCTTGTTGTGACAGGAAAAGAAATCTGGAACTATATTCCGGAAGAAGAAGTCGCCTACCGTTATCCGCC
AAGCTTGGTTCAGGATTCACGCAGTATTATTCAAGTTATTACGGGGCAGGCCGCGCTTACTAAAGACTTCGACGTAAAAG
CCGAGGGCAGGGAGGATGGCCTCTCCAAACTGCGCCTTTTCCCCAAGGAACCGGCGCCACAAATGGTGGAAGCCGTTATC
TGGGTGGAGCCTGACACCGGATATATCCGGCGGGCCAGCATCCTGGATTTTTACGGCAACAGTAATGAAGTGCGCTTTAA
TCGCTTTTCTCCGGACGTCAGCATCAAAGCTTCTGAATTCAGCTTTACACCGCCTAAGGGCGTGGATGTTGAAGATCGCA
TTGATAGCGCCGTACCCGAAAAAGAATTGTTTCGGTAA

Upstream 100 bases:

>100_bases
GCAGACGGCAGCAAGCCCCGCGCGGTGGTCAAATAACCTGAGCAGATTTTTTTTGAGATTGATTTTTCTGTCAGAGGCCC
CACCGGGCCGTGGAGGTTGT

Downstream 100 bases:

>100_bases
CGCCGGAAAAAGCGGATAATCAAGAGGAACTGATCAAGCCGTGACGCAAAATGCGTCACGGCTTTTCTTCCCCTGATTTT
TGAGTGACGTAGCGTGGGGA

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRMLRAAIAAMALCLIMTSFATAQNTDMAAAIQARYEKLGSFAADFDQTLTHKESGAVEKRQGKLLFKKPLLIRWQTVTP
HEETLVVTGKEIWNYIPEEEVAYRYPPSLVQDSRSIIQVITGQAALTKDFDVKAEGREDGLSKLRLFPKEPAPQMVEAVI
WVEPDTGYIRRASILDFYGNSNEVRFNRFSPDVSIKASEFSFTPPKGVDVEDRIDSAVPEKELFR

Sequences:

>Translated_225_residues
MRMLRAAIAAMALCLIMTSFATAQNTDMAAAIQARYEKLGSFAADFDQTLTHKESGAVEKRQGKLLFKKPLLIRWQTVTP
HEETLVVTGKEIWNYIPEEEVAYRYPPSLVQDSRSIIQVITGQAALTKDFDVKAEGREDGLSKLRLFPKEPAPQMVEAVI
WVEPDTGYIRRASILDFYGNSNEVRFNRFSPDVSIKASEFSFTPPKGVDVEDRIDSAVPEKELFR
>Mature_225_residues
MRMLRAAIAAMALCLIMTSFATAQNTDMAAAIQARYEKLGSFAADFDQTLTHKESGAVEKRQGKLLFKKPLLIRWQTVTP
HEETLVVTGKEIWNYIPEEEVAYRYPPSLVQDSRSIIQVITGQAALTKDFDVKAEGREDGLSKLRLFPKEPAPQMVEAVI
WVEPDTGYIRRASILDFYGNSNEVRFNRFSPDVSIKASEFSFTPPKGVDVEDRIDSAVPEKELFR

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=201, Percent_Identity=27.363184079602, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 25392; Mature: 25392

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLRAAIAAMALCLIMTSFATAQNTDMAAAIQARYEKLGSFAADFDQTLTHKESGAVEK
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RQGKLLFKKPLLIRWQTVTPHEETLVVTGKEIWNYIPEEEVAYRYPPSLVQDSRSIIQVI
HCCCEEEECCEEEEEEECCCCCCEEEEECHHHHCCCCCCCCEECCCHHHHHHHHHHHHHH
TGQAALTKDFDVKAEGREDGLSKLRLFPKEPAPQMVEAVIWVEPDTGYIRRASILDFYGN
HCCHHCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHEEEEEEECCCCCCEEHHHEEEECCC
SNEVRFNRFSPDVSIKASEFSFTPPKGVDVEDRIDSAVPEKELFR
CCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MRMLRAAIAAMALCLIMTSFATAQNTDMAAAIQARYEKLGSFAADFDQTLTHKESGAVEK
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RQGKLLFKKPLLIRWQTVTPHEETLVVTGKEIWNYIPEEEVAYRYPPSLVQDSRSIIQVI
HCCCEEEECCEEEEEEECCCCCCEEEEECHHHHCCCCCCCCEECCCHHHHHHHHHHHHHH
TGQAALTKDFDVKAEGREDGLSKLRLFPKEPAPQMVEAVIWVEPDTGYIRRASILDFYGN
HCCHHCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHEEEEEEECCCCCCEEHHHEEEECCC
SNEVRFNRFSPDVSIKASEFSFTPPKGVDVEDRIDSAVPEKELFR
CCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA